• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.1
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• pp.23-28
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• 2004

The aim of this study is to assess the anti-irritation activities of mung bean (Phaseolus aureus) extract against various irritants used in cosmetics. For its antidotal activity, mung bean has been used as a medicinal or cosmetic material since ancient times. However, there have been few reports describing the biological activities of these beans and no comprehensive surveys of the constituents. We obtained an ethanolic extract of mung bean and isolated the major constituents, such as vitexin and isovitexin. And we previously reported that the mung bean extract containing vitexin and isovitexin had excellent antioxidant and anti-inflammatory activities. To investigate the mechanisms of anti-inflammatory activity of mung bean extract, we examined the inhibitory effects on histamine release from rat peritoneal mast cells and lipoxygenase activity. Mung bean extract inhibited histamine release in a concentration dependent manner but showed no inhibitory activity in the 5-lipoxygenase assay. And, clinical studies were conducted to evaluate the anti-irritation effects of mung bean extract against various irritants used in cosmetics such as lactic acid, retinol, and preservatives. When 2.0％ of mung bean extract was applied to cosmetic formulae containing each of irritants, it revealed considerable anti-irritation efficacy. Our results of the human patch test with 20 volunteers showed that this extract reduced skin irritations caused by 5.0％ lactic acid, 4000 IU retinol, and 1.0％ preservative mixture by about 60％, 30％, and 50％ respectively. The stinging potential test for assessing subjective irritation also showed that the extract reduced the unpleasant sensations by about 50∼30％. Finally, we performed a double-blind usage test with 30 subjects to compare formulae containing mung bean extract with placebo. From the results of questionnaires for 4 weeks of use, we confirmed the excellent anti-irritation effect of mung bean extract. Conclusively, we could discover new material that had anti-irritation effects and apply this mung bean extract to the final cosmetic products successfully.

• Journal of Life Science
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• v.29 no.4
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• pp.442-446
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• 2019

We recently reported the characteristics of Chrysanthemum boreale MAKINO essential oil (CBMEO) at different harvesting stages and its in vitro antioxidant, whitening, skin regeneration, and antiwrinkle properties. In the present study, we investigated the effectiveness of cosmetic creams containing 0.1% of CBMEO in terms of wrinkle reduction and safety. The participants were 22 women aged 42 to 60 y with natural wrinkles. All the participants applied the CBMEO-containing cream to the eye area for 8 weeks. Visual observations of the skin by a dermatologist were used to assess the safety of the product, and improvements in skin wrinkles (roughness) were analyzed using a skin visiometer. Neither the CBMEO-containing cream nor the placebo caused abnormal reactions, such as erythema or allergies, during the test period. The CBMEO-containing cream-exposed test regions showed a greater reduction in the roughness index as compared with those of the placebo-exposed control regions. The R1, R2, and R3 indices showed a statistically significant decrease in the test regions as compared with the placebo control regions after using the cream for 2 weeks (p<0.05). Therefore, this study demonstrated that CBMEO-containing cosmetics are safe for human use and that they have skin wrinkle improvement properties. In the future, CBMEO may be a promising product for use in the development of functional anti-wrinkle cosmetics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.3
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• pp.534-544
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• 2017

In order to use the sea flowering plant, Zostera marina, as a cosmetic ingredient, this study was conducted to evaluate its antioxidant effect. We confirmed the formulation stability of the emulsion containing Zostera marina extracts. We studied the antioxidant activity of the dissolved Zostera marina extracts through the DPPH (1,1-Diphenyl-2-picrylhydrazy) radical scavenging activity assay and SOD (superoxide dismutase)-like activity assay. Also, the pH, viscosity and particle dispersion of the emulsion containing Zostera marina extracts were measured using a Turbiscan LAB. The emulsions were measured at one-week intervals in a thermostat chamber ($25^{\circ}C{\pm}1^{\circ}C$, $40^{\circ}C{\pm}1^{\circ}C$) for 28 days. The extracts of Zostera marina showed a DPPH radical scavenging rate of 86.21% and SOD-like activity of 99.24% at 5.00 mg/ml and exhibited a dose-dependent increase in their antioxidant activity. We measured the stability of the pH, viscosity and emulsion particles using the Turbiscan LAB in a thermostat chamber for 28 days. The formulations to which the Zostera marina extracts were added were considered to be stable, due to their negligible physical property changes over time during storage. The results suggest that the Zostera marina extracts with 70% ethanol (v/v) could be used in cosmetics as an antioxidant for the anti-aging of skin.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.4
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• pp.349-357
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• 2014

In this study, the shoot clumps extract of tissue-cultured Raoulia australis using the bioreactor culture system was tested for use a natural cosmetic ingredient. Tissue-cultured R. australis shoot clumps extract was tested anti-oxidant and anti-inflammatory activity for a cosmetic application. R. australis is a wild herbaceous plant of the asteraceae growing in New Zealand and Australia. Previous studies have reported anti-viral activity of the inhibitory effects for the growth of viruses induced meningitis, bronchitis and respiratory diseases but other biological effects are unknown. The shoot clumps extract of tissue-cultured R. australis showed higher anti-oxidant effect and anti-inflammatory effect than the natural R. australis extract. In DPPH, NBT and ABTS assay, the shoot clumps extract of tissue-cultured R. australis enhanced radical scavenging activity (up to 10~25% at $50{\mu}L/mL$) more than the natural R. australis extract. Also, the shoot clumps extract of tissue-cultured R. australis inhibited expression of iNOS and COX-2 protein in LPS-stimulated Raw 264.7 macrophages more than the natural R. australis extract. From this study, the shoot clumps extract of tissue-cultured R. australis displayed strong possibility as a new natural cosmetic ingredient for skin-care products.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.1
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• pp.83-90
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• 2011

Priming refers to the incidental activation of knowledge structures, such as trait concepts and stereotypes, by the current situational context. Many studies have shown that the recent use of a trait construct or stereotype, even in an earlier or unrelated situation, carries over for a time to exert an unintended, passive influence on the interpretation of behavior. Recent researches have shown that attitudes and other affective reaction can be triggered automatically by the mere presence of relevant objects and events. So assuming that behavioral responses to fragrance are also represented mentally, they should also be capable of becoming automatically activated, by the same principles that govern the development of automaticity of other representations. On the basis of this theory, this study examined the effect of fragrance on the quality of cosmetic products.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.4
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• pp.321-330
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• 2022

This study attempted to establish an optimal multi-compound simultaneous analysis method that can secure reliable results for 15 - preservatives, 2 - sun screens and 1 - antioxidants of cosmetics using HPLC-PDA. Since the potential of hydrogen (pH) in the mobile phase affects the acid dissociation constant (pKa) of the preservatives, and the peak retention time shift and area change were observed. The peak separation condition was established by adjusting the pH to 0.1% H₃PO₄ addition (mL) when preparing the mobile phase. As a results of method validation, the linearity correlation coefficient (R²) of above 0.999 were obtained, and accuracy 87.9 ~ 101.1%, 0.1 ~ 7.6% precision for two types of cosmetics (cream and shampoo). It was found that the limit of detection (LOD) was 0.1 ~ 0.2 mg/kg and the limit of quantitation (LOQ) was 2.0 ~ 4.0 mg/kg. In addition, it was possible to simultaneously separate p-anisic acid, a natural compound that was difficult to separate in HPLC due to the small difference from methylparaben, a synthetic preservatives. Through this study, it will be effectively used to secure quality control and safety for compound that need restrictions on use cosmetics.

• Journal of Korea Entertainment Industry Association
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• v.15 no.7
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• pp.271-280
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• 2021

The purpose of this study was to conduct a subjective and objective evaluation to verify the improvements in acne skin conditions followed by the use of foam cleanser, skin toner, and a facial pack that contains bamboo vinegar. The research targets are 20 male and female high school students in Gwangju and Jeolla regions with acne skin of grade II and above based on the Korean Acne Grading System (KAGS). For the experiment, the subjects were classified between an experimental group with 10 subjects who used bamboo vinegar foam cleanser, skin toner, and facial pack and a control group with 10 subjects who used foam cleanser, skin toner, and facial pack without bamboo vinegar, and the subjects had to use the foam cleanser, skin toner, and facial pack for 12 weeks. In the case of skin improvement effects founded upon the objective measurement values, the experimental group showed a greater improvement for reducing the pores in the forehead, nose ridge, and left cheek (p<.001) compared to the control group, and the experiment group had higher satisfaction overall even for the skin improvement effects based on the subjective evaluation tool (p<.05, p<.001). The overall values of the satisfaction of the cosmetics showed that the experiment group had higher values (p<.01, p<.001) compared to the control group for the foam cleanser, skin toner, and facial pack, and there were statistically significant differences for usability in details (p<.01, p<.001). In conclusion, it was proven that bamboo vinegar is an effective natural cosmetic product material to improve acne skin conditions.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.1
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• pp.77-84
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• 2024

Four children's cosmetic sets were purchased online, labeled for use from 4 years of age, and 81 components of each were analyzed for lead, cadmium, arsenic, antimony, nickel, cobalt, copper, chromium, and mercury by inductive coupled plasma - mass spectrometry (ICP - MS). The average metal concentrations were as follows: 0.82 ㎍/g for lead, 0.03 ㎍/g for cadmium, 0.97 ㎍/g for arsenic, 0.52 ㎍/g for antimony, 2.32 ㎍/g for nickel and 0.01 ㎍/g for mercury which was lower than the acceptable standards for all products. Higher mean values of lead, antimony, cobalt, and copper were detected in imported than domestic products (p < 0.05). There was a statistically significant difference in the average values of heavy metals according to the type of cosmetics (p < 0.05), with eyeshadow showing the highest mean values of arsenic 2.47 ㎍/g, nickel 6.36 ㎍/g, and chromium 11.06 ㎍/g. and the highest mean concentrations were 1.20 ㎍/g for lead, 1.17 ㎍/g for antimony, and 23.60 ㎍/g for copper in blusher. The levels of cobalt in the 81 children's cosmetics were ND ~ 5.23 ㎍/g, copper were ND ~ 379.61 ㎍/g, and chromium were detected ND ~ 36.95 ㎍/g, respectively. Brown colored cosmetics had the highest mean concentrations of nickel and cobalt. Purple-colored cosmetics had the highest mean concentration of lead and chromium.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.4
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• pp.413-420
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• 2016

Hydroxy acid has been used to enhance anti-aging and skin moisturization by peeling effect on the skin stratum corneum, and thus it has been widely used in topical products and cosmetic products. Among them, the effect that appears most effectively in a short period of time has been reported to be effected by the pH of the cosmetic formulations. However, there are many difficulties in use due to irritation caused by pH and concerns about side effects. The purpose of this study was to evaluate the effect of applying cosmetics with (1) varying concentrations, (2) types and (3) pH of hydroxy acid on human skin. 22 healthy adults were stained with DHA (dihydroxyacetone) and DC (dansyl chloride) on the forearm, and the skin exfoliation effect was measured after application of the test products. (1) The application of GA (glycolic acid) increased the desquamation by concentration dependent. (2) the test product prepared with neutral pH showed no exfoliation effect. In contrast, SA (salicylic acid) showed a statistically significant exfoliation effect at both acidic pH and neutral pH. (3) The neutral pH SA showed excellent exfoliation effect on bot DHA and DC stained stratum corneum. These results suggest that it is possible to manufacture safe cosmetics without damaging the skin barrier, providing an opportunity to use cosmetics that are expected to exfoliate to people, whose skin is sensitive to pH.

• Applied Microscopy
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• v.49
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• pp.2.1-2.11
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• 2019

Nanomaterials (NMs) find widespread use in different industries that range from agriculture, food, medicine, pharmaceuticals, and electronics to cosmetics. It is the exceptional properties of these materials at the nanoscale, which make them successful as growth promoters, drug carriers, catalysts, filters and fillers, but a price must be paid via the potential toxity of these materials. The harmful effects of nanoparticles (NPs) to environment, human and animal health needs to be investigated and critically examined, to find appropriate solutions and lower the risks involved in the manufacture and use of these exotic materials. The vast number and complex interaction of NM/NPs with different biological systems implies that there is no universal toxicity mechanism or assessment method. The various challenges need to be overcome and a number of research studies have been conducted during the past decade on different NMs to explore the possible mechanisms of uptake, concentrations/dosage and toxicity levels. This review article examines critically the recent reports in this field to summarize and present opportunities for safer design using case studies from published literature.