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http://dx.doi.org/10.5352/JLS.2019.29.4.442

A Study on the Anti-wrinkle Properties of Cosmetics Containing Essential Oil from Chrysanthemum boreale MAKINO  

Choi, In Ho (Division of Cosmetic and Biotechnology, College of Life and Health Science, Hoseo University)
Hwang, Dae Il (Division of Cosmetic and Biotechnology, College of Life and Health Science, Hoseo University)
Kim, Do Yoon (Division of Cosmetic and Biotechnology, College of Life and Health Science, Hoseo University)
Kim, Ha Bin (Division of Cosmetic and Biotechnology, College of Life and Health Science, Hoseo University)
Lee, Hwan Myung (Division of Cosmetic and Biotechnology, College of Life and Health Science, Hoseo University)
Publication Information
Journal of Life Science / v.29, no.4, 2019 , pp. 442-446 More about this Journal
Abstract
We recently reported the characteristics of Chrysanthemum boreale MAKINO essential oil (CBMEO) at different harvesting stages and its in vitro antioxidant, whitening, skin regeneration, and antiwrinkle properties. In the present study, we investigated the effectiveness of cosmetic creams containing 0.1% of CBMEO in terms of wrinkle reduction and safety. The participants were 22 women aged 42 to 60 y with natural wrinkles. All the participants applied the CBMEO-containing cream to the eye area for 8 weeks. Visual observations of the skin by a dermatologist were used to assess the safety of the product, and improvements in skin wrinkles (roughness) were analyzed using a skin visiometer. Neither the CBMEO-containing cream nor the placebo caused abnormal reactions, such as erythema or allergies, during the test period. The CBMEO-containing cream-exposed test regions showed a greater reduction in the roughness index as compared with those of the placebo-exposed control regions. The R1, R2, and R3 indices showed a statistically significant decrease in the test regions as compared with the placebo control regions after using the cream for 2 weeks (p<0.05). Therefore, this study demonstrated that CBMEO-containing cosmetics are safe for human use and that they have skin wrinkle improvement properties. In the future, CBMEO may be a promising product for use in the development of functional anti-wrinkle cosmetics.
Keywords
Anti-wrinkle; Chrysanthemum boreale Makino; elasticity; safety; skin visiometer;
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1 Kim, D. Y., Hwang, D. I., Yoon, M. S., Choi, I. H. and Lee, H. M. 2016. Effect of hydrosol extracted from chrysanthemum boreale Makino flower on proliferation and migration in human skin keratinocyte. J. Soc. Cosmet. Scientists Korea 42, 95-101.   DOI
2 Kim, D. Y., Won, K. J., Hwang, D. I., Park, S. M., Kim, B. and Lee, H. M. 2018. Chemical composition, antioxidant and anti-melanogenic activities of essential oils from Chrysranthemum boreale makino at different harvesting stages. Chem. Biodivers. 15, 1-13.
3 Kim, D. Y., Won, K. J., Yoon, M. S., Hwang, D. I., Yoon, S. W., Park, J. H., Kim, B. and Lee, H. M. 2015. Chrysanthemum boreale flower floral water inhibits platelet-derived growth factor-stimulated migration and proliferation in vascular smooth muscle cells. Pharm. Biol. 53, 725-734.   DOI
4 Kim, D. Y., Won, K. J., Yoon, M. S., Hwang, D. I., Yoon, S. W., Park, J. H., Kim, B. and Lee, H. M. 2015. Chrysanthemum boreale Makino essential oil induces keratinocyte proliferation and skin regeneration. Nat. Prod. Res. 29, 562-564.   DOI
5 Kim, J. M., Jeon, S. W., Lee, W. G., Nam, H. J. and Kim, Y. B. 2010. Study of preventing methods for skin aging and wrinkles. J. Physiol. Pathol. Kor. Med. 24, 533-542.
6 Kim, W. S., Park, B. S., Park, S. H., Kim, H. K. and Sung, J. H. 2009. Anti-wrinkle effect of adipose-derived stem cell: activation of dermal fibroblast by secretory factors. J. Dermatol. Sci. 53, 96-102.   DOI
7 Lee, H. H. 1999. The study of ageing phenomena and Anti-wrinkle treatment. J. Kor. Soc. Cosm. 5, 615-631.
8 Lee, H. K., Back, J. H., Koh, J. S., Park, D. H., Lee, J. S. and Jung, E. S. 2006. Correlation between skin roughness and dermal density of skin wrinkle evaluation. J. Soc. Cosmet. Scientists Korea 32, 123-127.
9 Lee, S. H., Hong, S. J., Kim, S. Y., Yang, H. I., Lee, J. D., Choi, D. Y., Lee, D. I. and Lee, Y. H. 2003. Randomized controlled double blind study of bee venom therapy on rheu matoid arthritis. J. Acupunct. Res. 20, 9-17.
10 Sangwan, N., Farooqi, A., Shabif, F. and Sangwan, R. 2001. Regulation of essential oil production in plants. Plant Growth Regul. 34, 3-21.   DOI
11 Yang, G., Lee, K., An, D. G., Lee, M. H., Ham, I. H. and Choi, H. Y. 2012. Effect of Chrysanthemi borealis flos on atopic dermatitis induced by 1-chloro 2, 4-dinitrobenzene in NC/ Nga mouse. Immunopharmacol. Immunotoxicol. 34, 413-418.   DOI
12 Yeo, J. J., Hsing, L. C., Yang, C. S., Jeong, S. I., Seo, E. S. and Jang, I. S. 2007. Effect of mahuang for weight loss in healthy adults : A double-blind, controlled, randomized, clinical Trial. J. Kor. Med. 28, 63-71.
13 Kang, S. J., Kim, A. J., Lee, M. S. and Lee, Y. H. 2010. Anti-wrinkle effect of oriental medicine cosmetics containing black ginseng. JKAIS. 11, 3325-3329.
14 Burt, S. 2004. Essential oils: their antibacterial properties and potential applications in foods a review. Int. J. Food Microbiol. 94, 223-253.   DOI
15 Choi, S. K., Park, K. D., Kim, D. A., Lee, D. W. and Kim, Y. J. 2014. Preparation of camel milk liposome and its antiaging effects. J. Soc. Cosmet. Scientists Korea 40, 155-162.   DOI
16 Figueiredo, A. C., Barroso, J. G., Pedro, L. G. and Scheffer, J. J. C. 2008. Factors affecting secondary metabolite production in plants: volatile components and essential oils. Flavour Frag. J. 23, 213-226.   DOI
17 Kim, B. S., Park, S. J., Kim, M. K., Kim, Y. H., Lee, S. B., Lee, K. H., Choi, N. Y., Lee, Y. R., Lee, Y. E. and You, Y. O. 2015. Inhibitory effects of Chrysanthemum boreale essential oil on biofilm formation and virulence factor expression of Streptococcus mutans. Evid.-based Complement Altern. Med. 2015, 1-11.
18 Kim, D. Y. 2016. Study on characterization and biological activities of essential oil from Korean indigenous plants. Ph. D. dissertation, Hoseo University, Asan, Korea.