Browse > Article
http://dx.doi.org/10.5762/KAIS.2017.18.3.534

A Study on the Antioxidative Effects of Zostera marina and its Application in Cosmatics  

Lee, So-Yeon (Division of Biomedicinal & Cosmetics, Mokwon University)
Yang, Jae-Chan (Division of Biomedicinal & Cosmetics, Mokwon University)
Kim, Bo-Ae (Division of Biomedicinal & Cosmetics, Mokwon University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.3, 2017 , pp. 534-544 More about this Journal
Abstract
In order to use the sea flowering plant, Zostera marina, as a cosmetic ingredient, this study was conducted to evaluate its antioxidant effect. We confirmed the formulation stability of the emulsion containing Zostera marina extracts. We studied the antioxidant activity of the dissolved Zostera marina extracts through the DPPH (1,1-Diphenyl-2-picrylhydrazy) radical scavenging activity assay and SOD (superoxide dismutase)-like activity assay. Also, the pH, viscosity and particle dispersion of the emulsion containing Zostera marina extracts were measured using a Turbiscan LAB. The emulsions were measured at one-week intervals in a thermostat chamber ($25^{\circ}C{\pm}1^{\circ}C$, $40^{\circ}C{\pm}1^{\circ}C$) for 28 days. The extracts of Zostera marina showed a DPPH radical scavenging rate of 86.21% and SOD-like activity of 99.24% at 5.00 mg/ml and exhibited a dose-dependent increase in their antioxidant activity. We measured the stability of the pH, viscosity and emulsion particles using the Turbiscan LAB in a thermostat chamber for 28 days. The formulations to which the Zostera marina extracts were added were considered to be stable, due to their negligible physical property changes over time during storage. The results suggest that the Zostera marina extracts with 70% ethanol (v/v) could be used in cosmetics as an antioxidant for the anti-aging of skin.
Keywords
Antioxidant; Emulsion Stability; Skin Aging; Turbiscan LAB; Zostera marina;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
연도 인용수 순위
1 A.A.M Botterweck, H Verhagen, R.A Goldbohm, J Kleinjans, P.A van den Brandt, "Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study", vol. 38, no. 7, pp. 599-605, 2000,   DOI
2 H. S. Jung, M. Y. Song, H. S. Kim, H. H. Seo, J. H. Lee, K. R. Lee, I. Hong, S. H. Moh, "Development of Anti-Wrinkle Materials using Galloyl-Peptide Derivatives", Journal of the Korea Academia-Industrial cooperation Society, vol. 16, no. 8, pp. 5452-5457, 2015. DOI: http://dx.doi.org/10.5762/KAIS.2015.16.8.5452   DOI
3 M. J. Kim, Y. G. Kim, H. S. Kim, C. Cheong, K. H. Jang, S. A. Kang, "Effects of Antioxidant Activities in Ethanol Extract of Apple Peel, Grape Peel, and Sweet Potato Peel as Natural Antioxidant", Journal of the Korea Academia-Industrial cooperation Society, vol. 15, no. 6, pp. 3766-3773, 2014. DOI: http://dx.doi.org/10.5762/KAIS.2014.15.6.3766   DOI
4 H. S. Kim, M. J. Kim, C. Cheong, S. A. Kang, "Antioxidant Properties in Water and 70% Ethanol Extracts of Houttuynia Cordata Thunb", Journal of the Korea Academia-Industrial cooperation Society, vol. 14, no. 10, pp. 5091-5096, 2013. DOI: http://dx.doi.org/10.5762/KAIS.2013.14.10.5091   DOI
5 E. I. Khasina, E. A. Kolenchenko, M. N. Sgrebneva, V. V. Kovalev, Yu. S. Khotimchenko, "Antioxidant Activities of a Low Etherified Pectin from the Seagrass Zostera marina", Russian Journal of Marine Biology, vol. 29, no. 4, pp. 259-261, 2003. DOI: https://doi.org/10.1023/A:1025493128327   DOI
6 K. F. Hua, H. Y. Hsu, Y. C. Su, I. F. Lin, S. S. Yang, Y. M. Chen, L. K. Chao, "Study on the Antiinflammatory Activity of methanol Extract from Seagrass Zostera japonica", J. Agric. Food Chem., vol. 54, no. 2, pp. 306-311, 2006. DOI: https://doi.org/10.1021/jf0509658   DOI
7 H. G. Kang, T. J. Kim, H. J Bae, H. J. Moon, M. K. Kim, D. H. Kim, S. w. Han, H. J. Lee, H. Y. Yang, M. K. Kim, "Effects of Reactive Oxygen Species on DNA Stability in Human Spermatozoa", Korean Journal of Biomedical Laboratory Sciences, vol. 7, no. 4, pp. 181-190, 2001.
8 K. Apel, H. Hirt, "Reactive oxygen species: metabolism, oxidative stress, and signal transduction", Annual Review of Plant Biology, vol. 55, pp. 373-472, 2004. DOI: https://doi.org/10.1146/annurev.arplant.55.031903.141701   DOI
9 J. K. Hong, "A Study on Skin Aging Caused by Free-Radical and on Efficacy of Antioxidant Vitamins", Asian Journal of Beauty and Cosmetology, vol. 7, no. 2, pp. 51-62, 2009.
10 C. M. Bergamini, S. Gambetti, A. Dondi, C. Cervellati, "Oxygen, Reactive Oxygen Species and Tissue Damage", Current Pharmaceutical Design, vol. 10, no. 14, pp. 1611-1626, 2004. DOI: https://doi.org/10.2174/1381612043384664   DOI
11 J. C. Ansel, T. A. Luger, D. Lowry, P. Perry, D. R. Roop, J. D. Mountz, "The expression and modulation of IL-1 alpha in murine keratinocytes", JOURNAL OF IMMUNOLOGY, vol. 140, no. 7, pp. 2274-2282, 1988.
12 L. Zuo, A. H. Hallman, W. J. Roberts, P. D. Wagner, M. C. Hogan, "Superoxide release from contracting skeletal muscle in pulmonary TNF-${\alpha}$ overexpression mice", A J P: Regulatory, Integrative and Comparative Physiology, vol. 306, no. 1, pp. 1522-1490, 2013.
13 G. M. Halliday, "Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis", Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, vol. 571, no. 1, pp. 107-120. 2004.   DOI
14 B. L. Diffey, P. R. Tanner, P. J. Matts, N. J. Frank, "In vitro assessment of the broad-spectrum ultraviolet protection of sunscreen products", Journal of the American Academy of Dermatology, vol. 43, no. 6, pp. 1024-1035, 2000. DOI: https://doi.org/10.1067/mjd.2000.109291   DOI
15 P. M. Elias, "Epidermal Lipids, Barrier Function, and Desquamation", Journal of Investigative Dermatology, vol. 80, pp. 44-49, 1983. DOI: https://doi.org/10.1111/1523-1747.ep12537108   DOI
16 W. Brand-Williams , M. E. Cuvelier, C. Berset, "Use of a free radical method to evaluate antioxidant activity", LWT - Food Science and Technology, vol. 28, no. 1, pp. 25-30, 1994. DOI: https://doi.org/10.1016/S0023-6438(95)80008-5   DOI
17 S. Chanda, R. Dave In vitro models for antioxidant activity evaluation and some medicinal plants possessing antioxidant properties: An overview, African Journal of Microbiology Research vol. 3, no. 13, pp. 981-996, 2009.
18 Y. J. Lee, A Study on Mineral and Alginic acid Contents by Different Pars of Sea Mustards(Undaria pinnatifida), Korean J. FOOD CULTURE, vol. 19, no. 6, pp. 691-700, 2004.
19 K. J. Cho, W. K. Cho, J. P. Lee, M. S. Kim, J. S. Kim, S. J. Hwang, "Evaluation of Glyceryl Monooleate(GMO) W/O Emulsion Stability by using Turbiscan (R)LAB", Journal of Pharmaceutical Investigation, vol. 39, no. 4, pp. 249-255, 2009. DOI: https://doi.org/10.4333/KPS.2009.39.4.249   DOI
20 C. Lemarchand, P. Couvreur, C. Vauthiera, D. Costantini, R. Gref, "Study of emulsion stabilization by graft copolymers using the optical analyzer Turbiscan LAB", International Journal of Pharmaceutics, vol. 254, no. 1, pp. 77-82, 2003. DOI: https://doi.org/10.1016/S0378-5173(02)00687-7   DOI
21 I. H. Song, "Changes in Fine Structures of keratinocytes Differentiation in Vitro-Study for Artificial Skin-", the Korean J, Anat., vol. 29, no. 2, pp. 159-170, 1996.
22 Y. Yamaguchi, K. Takahashi, B. Z. Zmudzka, A. Kornhauser, S. A. Miller, T. Tadokoro, W. Berens, J. Z. Beer, V. J. Hearing, "Human skin responses to UV radiation: pigment in the upper epidermis protects against DNA damage in the lower epidermis and facilitates apoptosis", the FASEB J., vol. 20, no. 9, pp. 1486-1488, 2006.   DOI
23 E. L. Seifert, C. Estey, J. Y. Xuan, M. E. Harper, "Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2 Emission during Long-chain Fatty Acid Oxidation", The Journal of Biological Chemistry, vol. 285, pp. 5748-5758, 2010. DOI: https://doi.org/10.1074/jbc.M109.026203   DOI
24 J. W. Kim, B. J. Cho, G. S. Han, "Effects of gradual loaded exercise on antioxidative enzymes response in normal and obese men", Journal of the Korea Academia-Industrial cooperation Society, vol. 11, no. 10, pp. 3820-3825, 2010.   DOI
25 M. Y. Choi, H. S. Song, H. S. Hur, S. S. Sim, "Whitening activity of luteolin related to the inhibition of cAMP pathway in ${\alpha}$-MSH-stimulated B16 melanoma cells", Archives of Pharmacal Research, vol. 31, no. 9, pp. 1166-1171, 2008. DOI: https://doi.org/10.1007/s12272-001-1284-4   DOI
26 M. E. Jung, J. W. Hong, J. I. Lee, C. S.Kong, J. S. Chang, Y. W. Seo, "Inhibitory Effect of Zostera japonica on Growth of Human Cancer Cells", Ocean and Polar Research, vol. 34, no. 4, pp. 385-394, 2012. DOI: https://doi.org/10.4217/OPR.2012.34.4.385   DOI
27 J. W. Hong, M. E. Jung, J. I. Lee, H. J. Kim, J. S. Chang, Y. W. Seo,"Cytotoxic Effect of Zostera asiatica on Growth of Human Cancer Cells", KSBB Journal, vol. 27, no. 4, pp. 227-231, 2012. DOI: https://doi.org/10.7841/ksbbj.2012.27.4.227   DOI
28 G. Seelinger, I. Merfort, C. M. Schempp, "Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin", Planta Medica, vol. 74, no. 14 pp. 1667-1744, 2008. DOI: https://doi.org/10.1055/s-0028-1088314   DOI
29 J. H. Kim, Y. H. Cho, S. M. Park, K. E. Lee, J. J. Lee, B. C. Lee, H. B. Pyo, K. S. Song, H. D. Park, Y. P. Yun, "Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves ofzostera marina L.", Archives of Pharmacal Research vol. 27, no. 2, pp. 177-183 2004. DOI: https://doi.org/10.1007/BF02980103   DOI
30 M. J. Kim, Y. G. Kim, H. S. Kim, C. Cheong, K. H. Jang, S. A. Kang, "Effects of Antioxidant Activities in ethanol Extract of Apple Peel, Grape Peel, and Sweet Potato Peel as Natural Antioxidant", Journal of the Korea Academia-Industrial cooperation Society, vol. 15, no. 6, pp. 3766-3773, 2014. DOI: http://dx.doi.org/10.5762/KAIS.2013.14.10.5091   DOI
31 H. S. Kim, H. Yun, "The Antioxidant Effect of Cheonggukjang, Fermented Using the New Strain, Bacillus amyloliquefaciens NBF11-1", Journal of the Korea Academia-Industrial cooperation Society, vol. 16, no. 8, pp. 5343-5350, 2015. DOI: http://doi.org/10.5762/KAIS.2015.16.8.5343   DOI