• 제목/요약/키워드: the standard of reference

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모집단 분포를 이용한 핵의학 혈액검사의 통계적 품질관리의 유용성 (Availability of Statistical Quality Control of Nuclear Medicine Blood Test Using Population Distribution)

  • 천준홍;조은빛;유선희;김년옥
    • 핵의학기술
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    • 제20권1호
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    • pp.37-41
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    • 2016
  • 정도관리(Quality Control)는 오차를 최소한으로 하여 검사의 신뢰도를 증진 시키는 것을 목적으로 하고 있으며 이러한 정도관리 활동을 통해 환자의 진단과 치료방침에 영향을 주는 핵의학 혈액 검사의 신뢰도가 확보되고 있다. 이에 연구자들은 신뢰도 향상의 추가적인 기법으로 건강검진 수검자를 대상으로 시행한 핵의학 혈액검사의 모집단 분포를 이용한 통계적 품질관리의 유용성을 평가해 보고자 한다. 2014년 1월부터 2014년 12월까지 서울아산병원 건강증진센터를 이용한 건강검진 수검자 41,341명을 대상으로 핵의학 혈액 검사 12종목에 대해 통계 분석을 시행 하였다. 통계분석은 핵의학 혈액 검사 12종목에 대한 결과 보고 치를 참고치 이내, 참고치 이상, 참고치 이하의 세 가지 그룹의 월간 백분율로 구분하여 모집단 분포의 평균값과 표준편차, 그리고 표준편차 지수(Standard Deviation Index: SDI)를 산출 하였고 그 결과 모집단 분포의 표준편차는 모든 그룹에서 대부분 ${\pm}2SD$ 이내의 결과를 보였다. 건강검진 수검자에 대한 핵의학 혈액검사 12종목(AFP, CEA, CA19-9, CA125, PSA, TSH, FT4, Anti-Tg-Ab, Anti-TPO-Ab, Calcitonin, 25-OH-VitD3, Insulin)의 모집단 분포를 분석한 결과 월간 백분율의 표준편차 지수(SDI)가 ${\pm}2.0$ 이상인 경우는, 1월과 3월 Insulin검사에서 각각 2.3, 2.4, 5월 Anti-Tg-Ab검사에서 2.2, 그리고 9월 CA19-9에서 2.2의 결과를 보였다. 이는 검사 Kit 시약의 이상 (동위원소 시약의 최대 결합률 저하), 검사반응 시간의 저하가 원인 이었다. 연구대상이 되는 전체의 속성을 포함하고 모집단 분포의 특성을 이용한 통계적 품질관리는 검사실에서 시행하고 있는 내부정도관리 프로그램을 보완하는 역할을 할 수 있으리라 생각된다.

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GPS 가상기준점 자료의 정확도 분석 (Accuracy Analysis of GPS Virtual Reference Station's Data)

  • 이용창
    • 한국측량학회:학술대회논문집
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    • 한국측량학회 2004년도 춘계학술발표회논문집
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    • pp.91-96
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    • 2004
  • More recently, multiple reference based RTK GPS techniques(VRS : Virtual Reference System) are becoming increasingly important for many precise GPS applications in many countries to overcome the constrained distance limitations of standard RTK systems. The precision of the position solutions of the rover receiver is closely connected with that of the corresponding virtual reference points(VRPs). The objective of this paper is to investigate the accuracy and performance of the VRPs on the test network for static positioning in post processing mode. For this, some VRPs at the inside and outside of test network have made in post mode, and the overall analysis results were presented by comparing the solution for the VRPs from the existed GPS reference station with the true values of the coordinates used to produce the observation data. The results show the reasonable accuracies of VRPs in the network area by using the VRS concept in post mode.

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보정계수 산출에 의한 신광원용 표준램프 광속의 검증 (The verification of Luminous flux of Reference illuminant for New light source by the calculated correction factor)

  • 황명근;신상욱;이진우
    • 전기학회논문지
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    • 제58권2호
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    • pp.369-372
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    • 2009
  • When measuring the luminous flux of a light source at the integrating sphere photometer, it can know the luminous flux to compare the standard lamp with the specimen lamp at the same location. But in case of PLS(plasma lighting system, microwave discharged lamp), that two lamps are cannot be the same location. If the reference illuminant and specimen lamp are cannot measure identical location, we should measure the variation of the luminous flux. For the outcome we can turn out a correction factor to revise and reflect it. But the better way is calibrate the specimen lamp locate the identical location of reference illuminant measured. In this thesis, we've test to find the correction factor for consider that change the measuring location. And it turns out the correction factor. From this, it presents the result to make a select for the reference illuminant which is against the illuminant type for newly produce.

Test Results of Dual-Use Wide-Area Differential GPS System for Extending the Operational Coverage

  • Kap Jin Kim;Jae Min Ahn
    • Journal of Positioning, Navigation, and Timing
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    • 제12권3호
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    • pp.307-314
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    • 2023
  • Wide-Area Differential Global Positioning System (WADGPS) is a system that operates a number of reference stations to provide correction information to improve the accuracy of GPS users, and it is available to service users within the area where the wide-area reference stations are installed. Recently, as positioning information has been used in various applications, the need for WADGPS for precise navigation in long-distance spaced areas where the wide-area reference stations cannot be installed has been raised. This paper tested the user navigation performance outside the wide-area reference stations of the WADGPS system, which serves both GPS Precise Positioning Service (PPS) and Standard Positioning Service (SPS) users. Static and dynamic tests were conducted using vehicles, and as a result, position accuracy improvement through WADGPS was confirmed even at points hundreds of kilometers outside the network area of the wide-area reference stations. Through this, the performance of the PPS/SPS correction system and the possibility of expanding the service area were confirmed.

Clinical Validation of a Deep Learning-Based Hybrid (Greulich-Pyle and Modified Tanner-Whitehouse) Method for Bone Age Assessment

  • Kyu-Chong Lee;Kee-Hyoung Lee;Chang Ho Kang;Kyung-Sik Ahn;Lindsey Yoojin Chung;Jae-Joon Lee;Suk Joo Hong;Baek Hyun Kim;Euddeum Shim
    • Korean Journal of Radiology
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    • 제22권12호
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    • pp.2017-2025
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    • 2021
  • Objective: To evaluate the accuracy and clinical efficacy of a hybrid Greulich-Pyle (GP) and modified Tanner-Whitehouse (TW) artificial intelligence (AI) model for bone age assessment. Materials and Methods: A deep learning-based model was trained on an open dataset of multiple ethnicities. A total of 102 hand radiographs (51 male and 51 female; mean age ± standard deviation = 10.95 ± 2.37 years) from a single institution were selected for external validation. Three human experts performed bone age assessments based on the GP atlas to develop a reference standard. Two study radiologists performed bone age assessments with and without AI model assistance in two separate sessions, for which the reading time was recorded. The performance of the AI software was assessed by comparing the mean absolute difference between the AI-calculated bone age and the reference standard. The reading time was compared between reading with and without AI using a paired t test. Furthermore, the reliability between the two study radiologists' bone age assessments was assessed using intraclass correlation coefficients (ICCs), and the results were compared between reading with and without AI. Results: The bone ages assessed by the experts and the AI model were not significantly different (11.39 ± 2.74 years and 11.35 ± 2.76 years, respectively, p = 0.31). The mean absolute difference was 0.39 years (95% confidence interval, 0.33-0.45 years) between the automated AI assessment and the reference standard. The mean reading time of the two study radiologists was reduced from 54.29 to 35.37 seconds with AI model assistance (p < 0.001). The ICC of the two study radiologists slightly increased with AI model assistance (from 0.945 to 0.990). Conclusion: The proposed AI model was accurate for assessing bone age. Furthermore, this model appeared to enhance the clinical efficacy by reducing the reading time and improving the inter-observer reliability.

Performance Evaluation of a BACnet-based Fire Detection and Monitoring System for use in Buildings

  • Song Won-Seok;Hong Seung-Ho
    • International Journal of Control, Automation, and Systems
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    • 제4권1호
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    • pp.70-76
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    • 2006
  • The objective of this paper is to propose a reference model of a fire detection and monitoring system using MS/TP protocol. The reference model is designed to satisfy the requirements of response time and flexibility. The reference model is operated on the basis of BACnet, a standard communication protocol for building automation systems. Validity of the reference model was examined using a simulation model. This study also evaluated the performance of the BACnet-based fire detection and monitoring system in terms of network-induced delay. Simulation results show that the reference model satisfies the requirements of the fire detection and monitoring system.

H.264 부호화를 위한 고속 다중 참조 화면 결정 기법 (Fast Multiple Reference Frame Selection for H.264 Encoding)

  • 정진우;최윤식
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.419-420
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    • 2006
  • In the new video coding standard H.264/AVC, motion estimation (ME) is allowed to search multiple reference frames for improve the rate-distortion performance. The complexity of multi-frame motion estimation increases linearly with the number of used reference frame. However, the distortion gain given by each reference frame varies with the video sequence, and it is not efficient to search through all the candidate frames. In this paper, we propose a fast mult-frame selection method using all zero coefficient block (AZCB) prediction and sum of difference (SAD) of neighbor block. Simulation results show that the speed of the proposed algorithm is up to two times faster than exhaustive search of multiple reference frames with similar quality and bit-rate.

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CMOS 아날로그 셀 라이브레이 설계에 관한 연구-CMOS 온-칩 전류 레퍼런스 회로 (A study on a CMOS analog cell-library design-A CMOS on-chip current reference circuit)

  • 김민규;이승훈;임신일
    • 전자공학회논문지A
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    • 제33A권4호
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    • pp.136-141
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    • 1996
  • In this paper, a new CMOS on-chip current reference circit for memory, operational amplifiers, comparators, and data converters is proposed. The reference current is almost independent of temeprature and power-supply variations. In the proposed circuit, the current component with a positive temeprature coefficient cancels that with a negative temperature coefficient each other. While conventional curretn and voltage reference circuits require BiCMOS or bipolar process, the presented circuit can be integrated on a single chip with other digiral and analog circits using a standard CMOS process and an extra mask is not needed. The prototype is fabricated employing th esamsung 1.0um p-well double-poly double-metal CMOS process and the chip area is 300um${\times}$135 um. The proposed reference current circuit shows the temperature coefficient of 380 ppm/.deg. C with the temperature changes form 30$^{\circ}C$ to 80$^{\circ}C$, and the output variation of $\pm$ 1.4% with the supply voltage changes from 4.5 V to 5.5 V.

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Computerized bone age estimation system based on China-05 standard

  • Yin, Chuangao;Zhang, Miao;Wang, Chang;Lin, Huihui;Li, Gengwu;Zhu, Lichun;Fei, Weimin;Wang, Xiaoyu
    • Advances in nano research
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    • 제12권2호
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    • pp.197-212
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    • 2022
  • The purpose of this study is to develop an automatic software system for bone age evaluation and to evaluate its accuracy in testing and feasibility in clinical practice. 20394 left-hand radiographs of healthy children (2-18 years old) were collected from China Skeletal Development Survey data of 1998 and China Skeletal Development Survey data of 2005. Three experienced radiologists and China-05 standard maker jointly evaluate the stages of bone development and the reference bone age was determined by consensus. 1020 from 20394 radiographs were picked randomly as test set and the remaining 19374 radiographs as training set and validation set. Accuracy of the automatic software system for bone age assessment is evaluated in test set and two clinical test sets. Compared with the reference standard, the automatic software system based on RUS-CHN for bone age assessment has a 0.04 years old mean difference, ±0.40 years old in 95% confidence interval by single reading, a 85.6% percentage agreement of ratings, a 93.7% bone age accuracy rate, 0.17 years old of MAD, 0.29 years old of RMS; Compared with the reference standard, the automatic software system based on TW3-C RUS has a 0.04 years old mean difference, a ±0.38 years old in 95% confidence interval by single reading, a 90.9% percentage agreement of ratings, a 93.2% bone age accuracy rate, a 0.16 years of MAD, and a 0.28 years of RMS. Automatic software system, AI-China-05 showed reliably accuracy in bone age estimation and steady determination in different clinical test sets.