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Study on Physicochemical Properties of Pesticide. (I) Water Solubility, Hydrolysis, Vapor Pressure, and n-Octanol/water Partition Coefficient of Captafol (농약의 물리화학적 특성연구 (I) Captafol의 수용성, 가수분해, 증기압, 옥탄올/물 분배계수)

  • Kim, Jeong-Han;Lee, Sung-Kyu;Kim, Yong-Hwa;Kim, Kyun
    • Applied Biological Chemistry
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    • v.40 no.1
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    • pp.71-75
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    • 1997
  • Important physicochemical properties of captafol [N-(1,1,2,2-tetrachloro-ethylthio)cyclohex-4-ene-1,2-dicarboximide], water solubility, vapor pressure, hydrolysis and octanol/water partition coefficient(Kow) were measured based on the standard EPA and OECD methods. Water solubility of the chemical was 2.24 ppm at $25^{\circ}C$. Half-life by hydrolysis at $25^{\circ}C$ in the buffer solution of pH 3.0, pH 7.0, and pH 8.0 was 77.8 hr, 6.54 hr and 0.72 hr, respectively, demonstrating instability in alkaline solution. The half-life in acid condition was not significantly different by temperature change, however, that in neutral or alkaline solution became shorter at $40^{\circ}C$. Hydrolysis study with a reference compound, diazinon, proved that the experimental method of the present study is reliable. Vapor pressure of captafol, $8.27{\times}10^{-9}$ torr at $20^{\circ}C$, was calculated from the equation, log P=6.94-(4401.6/T) plotted on the experiment results under different temperature conditions, 40, 50, and $60^{\circ}C$. pressure of captafol, the contamination of captafol would not happen easily in environment by vaporization. High Kow value of 1,523 was observed and this might result in bioconcentration through food chain when captafol was exposed. However, affecting human health through aquatic bioaccumulation is not likely to occur due to its rapid hydrolysis in the environment.

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Survey and method validation of simultaneous quantitative analysis of T-2 and HT-2 toxins in cereals (곡류 중 T-2 및 HT-2 독소 동시 정량분석의 유효성 검증 및 실태조사)

  • Paek, Ockjin;Kang, Teabeom
    • Food Science and Preservation
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    • v.22 no.4
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    • pp.559-566
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    • 2015
  • The aim of this study was to develop an analytical method for determination of T-2 toxin and HT-2 toxin level in cereals and to survey their levels using LC-MS/MS. The T-2 and HT-2 toxins were simultaneously analyzed by electrospray ionization with a positive ion mode and multiple reaction monitoring (MRM) after filteration and immuno-affinity column clean-up. A matrix-matched standard calibration used for quantification and recoveries of T-2 and HT-3 toxins were in the range of $100.6{\pm}7.2%$ and $96.8{\pm}9.4%$, respectively. Limits of detection and quantification of T-2 and HT-2 toxins were estimated to be 0.5 and $1.5{\mu}g/kg$, respectively. Each repeatability (RSRr) of T-2 and HT-2 toxins was determined to be 0.9~6.0%, and 4.9~6.1%, respectively. Total 115 samples cereals were collected from 9 types of cereals for analysis. The positive percentages of T-2 and HT-2 toxins obtained from collected samples were found to be 72% and 80%, respectively. The contamination level of T-2 toxin and HT-2 toxin in cereals were $37.1{\mu}g/kg$, and $5.4{\mu}g/kg$, respectively. Therefore, this study suggests that the developed method could be an useful analytical method to determine the T-2 and HT-2 toxin level in cereals and the present data could be used as a reference to estimate the risk assessment.

Analysis of Culture Filtrate Antigens of Aspergillus fumigatus Strains and of Antibody Responce in Patients with Aspergillosis by Immunoblotting (Immunoblotting 에 의한 Aspergillus fumigatus 균주(菌株)의 항원분석(抗原分析)과 이 균(菌)에 감염(感染)된 환자의 항체반응(抗體反應)에 관한 연구)

  • Kim, Sang-Jae;Kim, Sin-Ok;Hong, Young-Pyo
    • The Korean Journal of Mycology
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    • v.17 no.2
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    • pp.66-75
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    • 1989
  • Heterogeneity in antigenic composition of Aspergillus fumigatus isolates from clinical specimens and in antibody response of patients infected with this fungus was investigated by immunoblotting. A considerable quantitative and qualitative difference was found in composition of the culture filtrate antigens derived from a reference strain (ATCC 13073) and 8 clinical isolates of A. fumigatus on SDS-PAGE and immunoblots. The crude CF antigen of a strain AFG7 was selected to identify the serologically reactive and specific components by immunoblotting. Out of more than 36 components separated by electrophoresis, transblotted to nitrocellulose sheet, and reacted with sera that showed a positive reaction to A. fumigatus or other fungal antigens on immunodiffusion tests, merely four or so were found useful to serodiagnosis of aspergillosis. An antigen of 82KD was found most reactive and specific component so as to be contained in the standard preparation. Several other components, for example 11KD, 26KD, 30KD and 31KD, also possessed relatively high reactivity and specificity and seemed to be worth while purifying and characterizing. Antibody binding activity (reactivity) of the antigenic components was clearly shown on immunoblots because some were faintly stained with Coomassie blue but darkly stained on immunoblots, while some others behaved contrary to them. A number of components seemed to carry not only species specific but cross reactive antigenic determinants. Immunoblotting proved very useful to identify serologically reactive and specific components that should be present in the antigen to be employed to the serodiagnosis of aspergillosis.

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Image Quality Assessment Model of Natural Scene Based on Normal Distribution Analysis (일반 장면의 정규분포 분석을 기반으로 한 화질 측정 모형)

  • Park, Hyung-Ju;Har, Dong-Hwan
    • Science of Emotion and Sensibility
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    • v.16 no.3
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    • pp.373-386
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    • 2013
  • In this research, we specify the image consumers' preferred image quality ranges based on objective image quality evaluation factors and follow a method which measures preference of the natural image scenes. In other words, according to No-Reference, we select dynamic range, color, and contrast as factors of image quality measurements. For collecting sample images, we choose the preferred 200 landscapes which have over 30 recommendations by image consumers on the internet photo gallery. According to the scores of three objective factors of image quality measurements, the final expected score which means the image quality preference is measured and its total score is 100 points. In the main test, the actual image sample shows dynamic range 10 stop, LAB mean value L:54.7, A:2.96, B:-15.84, and RSC contrast 376.9. Total 200 image samples' normal distribution z value represents in dynamic range 0.21, LAB mean value L:0.15, A:0.38, B:0.13, and RSC contrast 0.08. In the standard normal distribution table, we can convert the z value as a percentage; dynamic range is 8.32%, LAB mean value is L:5.96%, A:14.8%, B:5.17%, and RSC contrast is 3.19%. And then, we convert the percentage values into the scores of 100; dynamic range is 91.68, LAB mean value is 91.36, and RSC contrast is 96.81. Therefore, we can conclude that the sample image's total mean score is 94.99 based on three objective image quality factors. Throughout our proposed image quality assessment model, we can measure the preference value of natural scenes. Also, we can specify the preferred image quality representation ranges and measure the expected image quality preference.

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Estimation of Longitudinal Dynamic Stability Derivatives for a Tailless Aircraft Using Dynamic Mesh Method (Dynamic Mesh 기법을 활용한 무미익 비행체 종축 동안정 미계수 예측)

  • Chung, Hyoung-Seog;Yang, Kwang-Jin;Kwon, Ky-Beom;Lee, Ho-Keun;Kim, Sun-Tae;Lee, Myung-Sup;Reu, Taekyu
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.3
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    • pp.232-242
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    • 2015
  • For stealth performance consideration, many UAV designs are adopting tailless lambda-shaped configurations which are likely to have unsteady dynamic characteristics. In order to control such UAVs through automatic flight control system, more accurate estimation of dynamic stability derivatives becomes essential. In this paper, dynamic stability derivatives of a tailless lambda-shaped UAV are estimated through numerically simulated forced oscillation method incorporating dynamic mesh technique. First, the methodology is validated by benchmarking the CFD results against previously published experimental results of the Standard Dynamics Model(SDM). The dependency of initial angle of attack, oscillation frequency and oscillation magnitude on the dynamic stability derivatives of a tailless UAV configuration is then studied. The results show reasonable agreements with experimental reference data and prove the validity and efficiency of the concept of using CFD to estimate the dynamic derivatives.

KFDA TLD Dose Quality Audit and Measurement Uncertainty (식품의약품안전청의 치료방사선 선량보증과 측정불확도)

  • Jeong, Hee-Kyo;Lee, Hyun-Ku;Kim, Gwe-Ya;Yang, Hyun-Kyu;Lim, Chun-Il
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2004.11a
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    • pp.153-156
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    • 2004
  • Korea Food and Drug Administration(KFDA) has peformed the calibration of therapy level dosimeters for Co-60 radiation since 1979. The reference standard ionization chamber has been calibrated at BIPM in France. The uncertainty on the KFDA calibration coefficients is 0.9 %(k=2) for air kerma and absorbed dose to water. Since 1999 a national quality audit program for ensuring dosimetry accuracy in Korea radiotherapy centers has been performed by the KFDA. The uncertainty associated with the determination of the absorbed dose to water from the TLD readings for high energy x-ray is 1.6 %(k=1). The correction factors for energy, non-linearity dose response, and TLD holder are used in the dose determination. Agreement between the user stated dose and KFDA measured dose within ${\pm}$ 5 % is considered acceptable. KFDA TLD postal dose quality audit program was peformed for 71 beam qualities of 53 domestic radiotherapy centers in 2003. The results for quality assurance showed that 63 out of 71 beam qualifies (89 %) satisfied the acceptance limit. The second audit was carried out for the centers outside the limit and ail of them have been corrected.

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The Error Pattern Analysis of the HMM-Based Automatic Phoneme Segmentation (HMM기반 자동음소분할기의 음소분할 오류 유형 분석)

  • Kim Min-Je;Lee Jung-Chul;Kim Jong-Jin
    • The Journal of the Acoustical Society of Korea
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    • v.25 no.5
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    • pp.213-221
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    • 2006
  • Phone segmentation of speech waveform is especially important for concatenative text to speech synthesis which uses segmented corpora for the construction of synthetic units. because the quality of synthesized speech depends critically on the accuracy of the segmentation. In the beginning. the phone segmentation was manually performed. but it brings the huge effort and the large time delay. HMM-based approaches adopted from automatic speech recognition are most widely used for automatic segmentation in speech synthesis, providing a consistent and accurate phone labeling scheme. Even the HMM-based approach has been successful, it may locate a phone boundary at a different position than expected. In this paper. we categorized adjacent phoneme pairs and analyzed the mismatches between hand-labeled transcriptions and HMM-based labels. Then we described the dominant error patterns that must be improved for the speech synthesis. For the experiment. hand labeled standard Korean speech DB from ETRI was used as a reference DB. Time difference larger than 20ms between hand-labeled phoneme boundary and auto-aligned boundary is treated as an automatic segmentation error. Our experimental results from female speaker revealed that plosive-vowel, affricate-vowel and vowel-liquid pairs showed high accuracies, 99%, 99.5% and 99% respectively. But stop-nasal, stop-liquid and nasal-liquid pairs showed very low accuracies, 45%, 50% and 55%. And these from male speaker revealed similar tendency.

A Study on Patients Dose and Image Quality according to Source to Image receptor Distance in Abdomen Radiography: comparison of ESD measured and DRLs in other countries (복부일반촬영시 선원과 검출기간의 거리변화에 따른 영상 화질 및 피폭선량에 관한 연구)

  • Jang, Ji-Sung;Choi, Weon-Keun;Jung, Jae-Yon;Lee, Kwan-Sub;Ha, Dong-Yoon
    • Korean Journal of Digital Imaging in Medicine
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    • v.14 no.2
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    • pp.39-46
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    • 2012
  • Purpose : The purpose of this study was to reduce Entrance Surface Dose and maintain image quality by changing Source to Image receptor Distance. And we'd like to compare ESD on this study to DRLs in other contries. Materials and Methods : We used indirect DR system(Definium 8000, General Electric, USA)and phantom(ART-200X, Flukebiomedical, USA),glass dosimeters(GD-352M, Asahi Techno Glass, Japan)for this study. The imagies were obtained throuh 80kVp fixed, and different tube currents using AEC mode in $16{\times}16$(inch) field size and changing Source to Image receptor Distance from 100 cm to 130 cm per 10 cm unit. The phantom with attaching 5 glass dosimeters on abdomonal skin was set at supine and erect position as a anterioposterial projection on detector For measuring Entrance Surface Dose. Image analysis was conducted by histograms of Image J(1.46r) which was given from National Institutes of Health(NIH). Results : Due to inverse square law of distance, the tube currents were increasing 42.6 % in supine position and 32.6 % in erect position according to the change of Source to Image receptor Distance. While Entrance Surface Doses were rapidly decreasing 14.2 % in supine position and 29.4 % in erect position according to the change of Source to Image receptor Distance. As the results of histogram using Image J, pixel mean values from 100 cm to 110 cm, 120 cm and 130 cm were decreasing each 1.4%, 2.5%, 2.7%, 4.5%, 2.2 %, 5.8 % in supine, erect position. While standard deviations from 100 cm to 110 cm, 120 cm and 130 cm were increasing each 1.4 %, 2.5 %, 2.5 %, 4.0 %, 2.0 %, 4.9 % Consequently, there are no significant differences in abdomen images taken. Conclusion: As the results described above, we strongly recommend using long Sourceto Image receptor Distance than 100cm that we have been using. So, we should deliver less Entrance Surface Dose to the patients while maintaining image quality in abdomen radiography.

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A Hardwired Location-Aware Engine based on Weighted Maximum Likelihood Estimation for IoT Network (IoT Network에서 위치 인식을 위한 가중치 방식의 최대우도방법을 이용한 하드웨어 위치인식엔진 개발 연구)

  • Kim, Dong-Sun;Park, Hyun-moon;Hwang, Tae-ho;Won, Tae-ho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.11
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    • pp.32-40
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    • 2016
  • IEEE 802.15.4 is the one of the protocols for radio communication in a personal area network. Because of low cost and low power communication for IoT communication, it requires the highest optimization level in the implementation. Recently, the studies of location aware algorithm based on IEEE802.15.4 standard has been achieved. Location estimation is performed basically in equal consideration of reference node information and blind node information. However, an error is not calculated in this algorithm despite the fact that the coordinates of the estimated location of the blind node include an error. In this paper, we enhanced a conventual maximum likelihood estimation using weighted coefficient and implement the hardwired location aware engine for small code size and low power consumption. On the field test using test-beds, the suggested hardware based location awareness method results better accuracy by 10 percents and reduces both calculation and memory access by 30 percents, which improves the systems power consumption.

Determination of vitamin B1 and B3 contents in Korean domestic foods using high performance liquid chromatography (고성능 액체크로마토그래피를 이용한 국내 식품자원의 비타민 B1과 B3 함량 분석)

  • Song-Yee Lee;So-Ra Choi;Eun-Ju Song;Eun-Ju Kim;Hyun-Ah Han
    • Food Science and Preservation
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    • v.30 no.1
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    • pp.98-108
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    • 2023
  • The purpose of this study was to determine the vitamin B1 and B3 contents in 135 Korean domestic foods using high performance liquid chromatography (HPLC). The Standard Reference Material (SRM) 3233 and in-house control (grain, whole wheat and flour mixture) were used for quality control/assurance. As a result, vitamin B1 was only detected in 54 of the 135 foods, ranging from 0.019 mg/100 g to 28.218 mg/100 g. Among the foods tested, the vitamin B1 content was highest in ramen powder (28.218 mg/100 g) and lowest in boiled jjolmyeon (0.019 mg/100 g). In contrast, vitamin B3 was detected in 108 of the 135 foods, ranging from 0.077 mg/100 g to 32.412 mg/100 g. We found that the vitamin B3 content was highest in beef liver (32.412 mg/100 g) and lowest in boiled chicken heart (0.077 mg/100 g). The results of this study will be used as a nutritional database for the update of the Korean food composition table and will hence contribute to improving public health.