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Design of the LDO Regulator with 2-stage wide-band OTA for High Speed PMIC (고속 PMIC용 2단 광대역 OTA방식의 LDO 레귤레이터 설계)

  • Kwon, Bo-Min;Song, Han-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.4
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    • pp.1222-1228
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    • 2010
  • This paper presents a design of the CMOS LDO regulator with a fast transient response for a high speed PMIC(power management integrated circuit). Proposed LDO regulator circuit consists of a reference voltage circuit, an error amplifier and a power transistor. 2-stage wide-band OTA buffer between error amplifier and power transistor is added for a good output stability. Although conventional source follower buffer structure is simple, it has a narrow output swing and a low S/N ratio. In this paper, we use a 2-stage wide-band OTA instead of source follower structure for a buffer. From HSPICE simulation results using a $0.5{\mu}m$ CMOS standard technology, simulation results were 16 mV/V line regulation and 0.007 %/mA load regulation.

Oxidative Cleavage Products of ${\zeta}-Carotene$ (${\zeta}-Carotene$의 산화개열산물)

  • Kim, Seon-Jae
    • Korean Journal of Food Science and Technology
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    • v.32 no.5
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    • pp.985-990
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    • 2000
  • ${\zeta}-Carotene$ was subjected to ozonolysis in ice-cold dichloromethane. The ozonolysis products were fractionated with a silica column and the carbonyl fraction was analyzed by ODS-HPLC with a photodiode array detector. ${\zeta}-Carotene$ was solubilized in toluene, and then oxidized by incubating at $37^{\circ}C$, 72 hr under atmospheric oxygen. Carbonyl compound and acidic compound were produced. In comparison with autoxidation and ozonolysis, each compound showed the same retention time and UV-vis spectra were identical to the reference cleavage products prepared by ozonolysis of ${\zeta}-carotene$. Absorption spectrum of acidic compound was similar to that of standard 4,5-didehydrogeranyl geranyl acid which is known to possess biological activity. Thus, eccentric cleavage of ${\zeta}-carotene$ was confirmed to occur in vitro under oxidation condition.

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Qualitative and quantitative PCR detection of insect-resistant genetically modified rice Agb0101 developed in korea (해충저항성 유전자변형 벼 Agb0101에 대한 PCR 검정)

  • Shin, Kong-Sik;Lee, Jin-Hyoung;Lim, Myung-Ho;Woo, Hee-Jong;Qin, Yang;Suh, Seok-Cheol;Kweon, Soon-Jong;Cho, Hyun-Suk
    • Journal of Plant Biotechnology
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    • v.40 no.1
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    • pp.18-26
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    • 2013
  • Genetically modified (GM) rice Agb0101, which expresses the insecticidal toxin modified cry1Ac (mcry1Ac1) gene, was developed by the Rural Development Administration in Korea. To monitor the probable release of Agb0101 in the future, it is necessary to develop a reliable detection method. Here, we developed the PCR detection method for monitoring and tracing of GM rice. The primer pair (RBEgh-1/-2) from a starch branching enzyme (RBE4) gene was designed as an endogenous reference, giving rise to an expected PCR amplicon of 101 bp. For the qualitative PCR detection, construct- and event-specific primers were designed on the basis of integration sequence of T-DNA. Event-specific PCRs amplified specifically 5'- or 3'-junction region spanning the native genome DNA and the integrated gene construct, while none of amplified product was shown on crops, rice varieties, and other insect-resistant transgenic rice lines. The event-specific real-time PCR method was performed using TaqMan probe and plasmid pRBECrR containing both rice endogenous gene RBE4 sequence and 5'-junction sequence as the reference molecule. The absolute limit of quantification (LOQ) of real-time PCR was established with around 10 copies for one plasmid molecule pRBECrR. Thereafter, the different amounts of transgenic rice (1, 3, 5, and 10%, respectively) were quantified by using the established real-time PCR method, with a range below 19.55% of the accuracy expressed as bias, 0.06-0.40 of standard deviation (SD) and 3.80-7.01% of relative standard deviations (RSD), respectively. These results indicate that the qualitative and quantitative PCR methods could be used effectively to detect the event Agb0101 in monitoring and traceability.

Consideration of the Effect according to Variation of Material and Respiration in Cone-Beam CT (Cone-Beam CT에서 물질 및 호흡 변화가 영상에 미치는 영향에 대한 고찰)

  • Na, Jun-Young;Kim, Jung-Mi;Kim, Dae-Sup;Kang, Tae-Young;Baek, Geum-Mun;Kwon, Gyeong-Tae
    • The Journal of Korean Society for Radiation Therapy
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    • v.24 no.1
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    • pp.15-21
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    • 2012
  • Purpose: Image Guided Radiation Therapy (IGRT) has been carried out using On-Board Imager system (OBI) in Asan Medical Center. For this reason, This study was to analyze and evaluate the impact on Cone-Beam CT according to variation of material and respiration. Materials and Methods: This study was to acquire and analyze Cone-Beam CT three times for two material: Cylider acryl (lung equvalent material, diameter 3 cm), Fiducial Marker (using clinic) under Motion Phantom able to adjust respiration pattern randomly was varying period, amplitude and baseline vis-a-vis reference respiration pattern. Results: First, According to a kind of material, when being showed 100% in the acryl and 120% in the Fiducial Marker under the condition of same movement of the motion phantom. Second, According to the respiratory alteration, when being showed 1.13 in the baseline shift 1.8 mm and 1.27 in the baseline shift 3.3 mm for acryl. when being showed 1.01 in 1 sec of period and 1.045 in 2.5 sec of period for acryl. When being showed 0.86 in 0.7 times the standard of amplitude and 1.43 in 1.7 times the standard of amplitude for acryl. when being showed 1.18 in the baseline shift 1.8 mm and 1.34 in the baseline shift 3.3 mm for Fiducial Marker. when being showed 1.0 in 1 sec of period and 1.0 in 2.5 sec of period for Fiducial Marker. When being showed 0.99 in 0.7 times the standard of amplitude and 1.66 in 1.7 times the standard of amplitude for Fiducial Marker. Conclusion: The effect of image size of CBCT was 20% in the case of Fiducial marker. The impact of changes in breathing pattern was minimum 13% - maximum 43% for Arcyl, min. 18% - max. 66% for Fiducial marker. This difference makes serious uncertainty. So, Must be stabilized breathing of patient before acquiring CBCT. also must be monitored breathing of patient in the middle of acquire. If you observe considerable change of breathing when acquiring CBCT. After Image Guided, must be need to check treatment site using fluoroscopy. If a change is too big, re-acquiring CBCT.

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Review of Emergency Procedures for CANDU Reactors (캔두형 원자력 발전소 비상절차서 검토)

  • Kim, S.R.;Kwon, J.S.;Cho, J.H.;Park, S.H.;Nam, S.K.
    • Nuclear Engineering and Technology
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    • v.27 no.4
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    • pp.571-581
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    • 1995
  • The generation, verification and validation of Emergency Procedures for Nuclear Power Plant is a difficult and complex process. Atomic Energy Control Board(AECB) requires that emergency procedure and plan be produced before obtaining the Operating License, that is, detailed plans and procedures to handle emergency situations for both on-site actions and off-site actions be developed. In this report Emergency Operating Procedures Standard for Canadian Nuclear Utilities which makes reference to U. S. practices and the current direction of emergency procedures for CAN-DU reactors are reviewed and compared based on scope(events covered), methodology (event-oriented or symptom-oriented or hybrid) and format(method of presentation) preponderantly, and an attempt is made to integrate these procedures and as a result the recommended strategy for Wolsong unit 2, 3, & 4 is presented as event-specific procedures, generic procedures(when event is not diagnosed) and whose format is combination of logic diagram and text.

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Fundamental research to investigate methods of vocational competency enforcement in field of home economics education - revision of the current NCS based vocational highschool education curriculum and investigation in change of direction in vocational home economics education - (가정과교육에서의 직업역량 강화 방안 탐색을 위한 기초 연구 - NCS 기반 고교 직업교육과정 개정과 가사실업계 직업교육의 변화 방향 탐색 -)

  • Jang, Myung Hee
    • Journal of Korean Home Economics Education Association
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    • v.26 no.4
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    • pp.129-146
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    • 2014
  • This study is a fundamental research in the field of home economics education to enforce vocational competencies. It was carried out in the purpose of examining the recent economical and social environmental changes and its management system related to the vocational training in the field of home economics education. It seeks change in direction in relation to the National Competency Standard(NCS) based on revisions in the educational system. The method of study was mostly through reference and data analysis, professional advisory and public hearing. The main research results are as follows. First, the main environmental change factors in relation to vocational training have been integrated to the changes in; population structure, gender related economic activities, generation composition, communications technology, and innovation of living technique. These change factors are forecasting innovations in related industries, lifestyle changes, demand for manpower and changes in capabilities required for each specific profession. Second, according to the analysis of current home economics education training, vocational home educations high school accounts for 9.4% of the total number of specialized high schools, where 8 standard departments are specialized in and characterized into 137 different department names. Despite differences among departments, overall employment rate of graduates were measured 44.7%, which rates above the entrance rate of 41.9%. These numbers show great change since 2010(overall employment rate 16.9%, entrance rate 75.2%), a meaningful outcome resulting from changes in policy from the previous employment-centered education system. Third, NCS based on high school vocational home economics education system revision and investigations in change of direction in vocational home economics, this study attempts to provide background for revision from the development of NCS. It also provides proposals for restructuring division of current classification and departments of home economics education, and propositions for further future research.

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A Proposal on Digital Cable TV Menu for 20's (20대 사용자를 위한 디지털 케이블 TV 메뉴 제안)

  • Kim, Yong-Seong;Noh, Ji-Hye;Park, Su-Bin;An, So-Hyeon;Yeoun, Myeong-Heum
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.1053-1058
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    • 2009
  • Digital cable TV(DCATV) is totally different with a existing TV which is passive, and can pick the contents anytime we want. It is very popular in many houses and we can see bright future with this. This study will show a standard that is a suitable and convenient VOD menu category for 20's through a various usability test. Moreover it will be provided new menu style and GUI through the preferences. For this, we found expected problems first through the heuristic analysis and did iterative usability test to verify and improve these problems. As a result of that, we improved errors of VOD menu structure and suggested new menu style including metaphor, colour and icon users can recognize easily. That is, VOD categories should be grouped among definite meanings. And we found using convenience is more important than new discovery of method on menu style for experienced users. This study can be not only based data when DCATV menu is renewed but also can be used as a reference data when designing other DCATV menu.

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Evaluation of Uncertainty of IMRT QA Using 2Dimensional Array Detector for Head & Neck Patients (두경부암에서 2차원 배열 검출기를 이용한 IMRT QA의 불확실성에 대한 연구)

  • Ban, Tae-Joon;Lee, Woo-Suk;Kim, Dae-Sup;Baek, Geum-Mun;Kwak, Jung-Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.23 no.2
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    • pp.97-102
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    • 2011
  • Purpose: IMRT QA using 2Dimensional array detector is carried out with condition for discrete dose distribution clinically. And it can affect uncertainty of evaluation using gamma method. We analyze gamma index variation according to grid size and suggest validate range of grid size for IMRT QA in Hospital. Materials and Methods: We performed QA using OniPro I'mRT system software version 1.7b on 10 patients (head and neck) for IMRT. The reference dose plane (grid size, 0.1 cm; location, [0, 0, 0]) from RTP was compared with the dose plane that has different grid size (0.1 cm, 0.5 cm, 1.0 cm, 2.0 cm, 4.0 cm) and different location (along Y-axis 0 cm, 0.2 cm, 0.5 cm, 1.0 cm). The gamma index variation was evaluated by observing the level of changes in Gamma pass rate, Average signal, Standard deviation for each case. Results: The average signal for each grid size showed difference levels of 0%, -0.19%, -0.04%, -0.46%, -8.32% and the standard deviation for each grid size showed difference levels of 0%, -0.30%, 1.24%, -0.70%, -7.99%. The gamma pass rate for each grid size showed difference levels of 0%, 0.27%, -1.43%, 5.32%, 5.60%. The gamma evaluation results according to distance in grid size range of 0.1 cm to 1.0 cm showed good agreement with reference condition (grid size 0.1 cm) within 1.5% and over 5% in case of the grid size was greater than 2.0 cm. Conclusion: We recognize that the grid size of gamma evaluation can make errors of IMRT QA. So we have to consider uncertainty of gamma evaluation according to the grid size and apply smaller than 2 cm grid size to reduce error and increase accuracy clinically.

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A study of sagittal condylar inclination and occlusal plane inclination of two semiadjustablearticulators with different reference plane (기준면이 다른 반조절성 교합기의 전방시상과로각과 교합평면경사각에 대한 연구)

  • Kim, Hyo-Jung;Lee, Sung-Bok;Choi, Dae-Gyun;Bak, Jin
    • The Journal of Korean Academy of Prosthodontics
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    • v.46 no.4
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    • pp.420-430
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    • 2008
  • Statement of problem & Purpose: Articulators are very important for education and overall clinical situation in the field of prosthodontics, however preexisting articulators are designed and built based on maxillofacial structures and mean values of mandibular movement of Western people. Purpose of this research is to find out a adequate basis for applicating these articulators, presently used for clinical education, for Korean. Material and methods: 59 Korean adults (41 males, 18 females), aged between 24 to 41, where selected for this study. Two pairs of both maxillary and mandibular models were made for each examinee. These models where attached to both KaVo PROTARevo 7 and Hanau Modular semiadjustable articulators by using facebow transfer, than sagittal condylar inclination, occlusal plane inclination and position of mandibular on the articulator where measured. Result and conclusion: 1. Mean sagittal condylar inclination for KaVo PROTAR semiadjustable articulator was $33.75^{\circ}$(standard deviation $12.46^{\circ}$) meanwhile Hanau Modular semiadjustable articulator showed $40.72^{\circ}$(standard deviation $12.09^{\circ}$) for mean sagittal condylar inclination. 2. Mean occlusal plane inclination for KaVo PROTAR semiadjustable articulator was $-2.76{\circ}$(standard deviation $3.63^{\circ}$) meanwhile Hanau Modular semiadjustable articulator showed $11.87^{\circ}$ (standard deviation $3.63^{\circ}$) for mean occlusal plane inclination. 3. On the average center of the mandibular dentition were in the range of 5 to 7 mm of the central position of the articulator. Both anterior and posterior dentition were positioned at the center of the articulator vernacularly for KaVo PROTAR semiadjustable articulators, meantime for Hanau Modular semiadjustable articulator, anterior dentition was positioned 5 mm downwards and 3mm upwards for posterior dentition from vertically central position of the articulator.

Evaluation of the Feasibility of Applying Metabolic Target Volume in 4D RT Using PET/CT Image (4D RT에서 PET/CT Image를 이용한 Metabolic Target Volume 적용의 유용성 평가)

  • Kim, Chang-Uk;Chun, Keum-Sung;Huh, Kyung-Hoon;Kim, Yeon-Shil;Jang, Hong-Seok;Jung, Won-Gyun;Xing, Lei;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.174-182
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    • 2010
  • In this study, we evaluated feasibility of applying MTV (Metabolic Target Volume) to respiratory gated radiotherapy for more accurate treatment using various SUV (Standard Uptake Value) from PET images. We compared VOI (Volume of Interest) images from 50%, 30% and 5% SUV (standard uptake volume) from PET scan of an artificial target with GTV (Gross Tumor Volume) images defined by percentage of respiratory phase from 4D-CT scan for respiratory gated radiotherapy. It is found that the difference of VOI of 30% SUV is reduced noticeably comparing with that of 50% SUV in longitudinal direction with respect to total GTV of 4D-CT image. Difference of VOI of 30% SUV from 4D-PET image defined by respiratory phase from 25% inhalation to 25% exhalation, and GTV from 4D-CT with the same phase is shown below 0.6 cm in maximum. Thus, it is better to use 4D-PET images than conventional PET images for applying MTV to gated RT. From the result that VOI of 5% SUV from 4D-PET agrees well with reference image of 4D-CT in all direction, and the recommendation from department of nuclear medicine that 30% SUV be advised for defining tumor range, it is found that using less than 30%SUV will be more accurate and practical to apply MTV for respiratory gated radiotherapy.