• Research in Plant Disease
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• v.26 no.4
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• pp.279-282
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• 2020

In 2019, symptoms of Botrytis mold on the peony (Paeonia lactiflora Pall.) 'Sarah Bernhardt' were observed during a survey of the commercial greenhouses of Gangjin County, South Korea. The initial symptoms, small brown spots, were observed mainly at the leaf margins. The lesions extended to the interior of leaves forming irregular spots in which abundant conidia developed. Fungal colonies were obtained from surface-sterilized tissue excised from growing edges of the lesions that were transferred to potato dextrose agar. Melanized irregular sclerotia were formed in these colonies after 40 days at 8℃. Molecular phylogeny based on sequences of genes for glyceraldehyde-3-phosphate dehydrogenase, heat-shock protein 60, and RNA polymerase subunit II were highest for the PBC-2 isolate to the type strains of Botrytis cinerea, rather than other Botrytis species associated with peony diseases. Following Koch's postulates, healthy Sarah Bernhardt plants were inoculated with a foliar application of conidial suspensions of the isolate PBC-2. Following incubation under humidity with a 12 hr photoperiod for 7 days, symptoms developed on the leaf margins that were identical to those observed in the greenhouses. This study is the first report of Botrytis blight caused by B. cinerea on peonies grown in commercial greenhouses in South Korea.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.4
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• pp.574-579
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• 2005

Optimal management of indoor air quality in a confined pig house, especially in winter, is indispensable for preventing infectious respiratory disease to workers and animals. This study was performed to elucidate the correlation of aerial contaminants and climate factors in a confinement. It was observed that indoor air contaminants ion in the confinement was the highest at 2:00-5:00 pm in a day, followed by 8:00-11:00 pm and 8:00-11:00 am. This was attributed to the increase of pig activities in the afternoon. The concentration of total dust and total airborne bacteria was found to have a significant correlation with temperature and relative humidity (p<0.05). Correlation of total dust and total airborne bacteria, total dust and ammonia, and total dust and odor were shown statistically significant at 95% confidence level. In conclusion, temperature and total dust concentration correlated significantly with all the parameters except for hydrogen sulfide ($H_2S$). This could be explained by the fact the dryness of pig feces by increase of interior temperature and resuspension of feed deposited on the floor by the pig activity, resulted in high generation of dust which adsorbed and carried the airborne bacteria and odor compounds in a confined pig house. It was proved that the adsorptive capacity of dust with ammonia ($NH_3$) was higher than that with hydrogen sulfide ($H_2S$).

• Journal of Sasang Constitutional Medicine
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• v.22 no.1
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• pp.9-16
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• 2010

1. Background: GalgeunNabokja-Tang(葛根蘿葍子湯) is suggested as treatment and prescription of Exterior Heat syndrome Diarrhea(表熱證泄瀉) in Donguisusebowon Tae-eumin Interior febrile disease induced form the liver affected by heat("東醫壽世保元" "太陰人肝受熱裏熱病論"), but is not recorded the treatment contents in Sinjungbang("新定太陰人病應用要藥二十四方"). 2. Methods: Accordingly, the writer surveyed, compared, and arranged the relevant contents by collecting books of doctors of Four-Constitutional Medicine(四象醫) since Lee Je-ma including Lee Je-ma's books. 3. Results: and Conclusions: 1) The treatment contents in GalgeunNabokja-Tang are thought to be valid to have the criterion as the contents of appearing in SanggyohyuntoDonguisusebowon Boyubang("詳校懸吐東醫壽世保元" "補遺方"). 2) The origin in GalgeunNabokja-Tang is GalgeunNabokja-Tang in Bimang-lok("備忘錄"). And the period of having made treatment for the first time may be estimated to be the one between Donguisuse- bowonSasangchobonguan("東醫壽世保元四象草本卷") and HamsansachonDonguisusebowonGabogubon ("咸山沙村東醫壽世保元甲午舊本"). 3) GalgeunNabokja-Tang is thought to be probably what Han Du-jeong recorded in Boyubang by searching for what Lee Je-ma modified some of GalgeunNabokja-Tang in Bimang-lok while writing Pathological Syndromes("病證論") in Donguisusebowon("東醫壽世保元").

• Journal of Korean Medical classics
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• v.30 no.2
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• pp.99-112
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• 2017

Objectives : 28 prescriptions with the name 'Dossi' can be found in Yixuerumen, and all these prescriptions are highly useful due to their clinical effectiveness. Among them, Dossisosihotang has an important role as the essential prescription utilizing harmonizing and releasing formula. Therefore, this paper aims to ponder upon this prescription. Methods : Dossisosihotang's origin and effectiveness were studied, and the findings served as the basis for analyzing the varied forms of this prescription which came about in the later generations in order to consider more detailed usage of this prescription. Results & Conclusions : Dossisosihotang directs its patient to consume sosihotang added with chenpi, shaoyao, chuanxiong, then simmered, and added with three spoons worth of raw wormwood juice. Its origin can be traced back to shachechuifa's 'Sihossanghaeeum,' and it is mainly effective for treating the blood aspect syndrome of lesser yang disease such as women's cold damage and heat entering the blood chamber. In treating the symptom of half-exterior and half-interior, taohua developed prescriptions depending on the syndrome, such as Sihijigyungtang, Sihohamhyoungtang, Samhosambacktang, Siryungtang, Sihosamultang, Sigalhaegitang, and Samhoseoggotang. These prescriptions became widely known for their clinical efficacy, leading to many later generations of clinical doctors to use them.

• KIEAE Journal
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• v.10 no.1
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• pp.19-24
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• 2010

Modern people are spending most of time in interior area. Indoor air environmental problem is one of the most effective factors influenceable to human health. Furthermore, saving energy and making ventilation system for pleasant indoor environment are necessary when it is faced shortage of energy over the world. In our country's case, it is already imposed that required quantity of air ventilation in buildings is 0.7 times per hour on "The regulation on building engineering system". As on the rise of the interests about Indoor air environment, Heat and Carbon dioxide emissions from User's metabolism, activity, furniture, and construction materials etc. could be the causes of Indoor air pollution. If these materials stays in Indoor air for so long, it could directly influence the user's health condition with a disease. As of building's sterilization improved that raised more mechanical ventilation. It also leads much energy waste in a period of high price of fossil fuel. Therefore, the way that saves energy and effective control of indoor ventilation is urgently needed. So, this study places the purpose on validating volume of indoor ventilation and user's comfortable degree by comparison CO2 emission rate through changing floor temperature.

• Journal of The Korea Institute of Healthcare Architecture
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• v.29 no.2
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• pp.49-60
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• 2023

Purpose: This study aims to establish detailed spatial planning by identifying the needs for a seclusion module for emergency psychiatric patients. Methods: The necessity of medical space with seclusion function was analyzed from spatial, medical, and social perspectives. The needs for a space capable of performing three medical functions: protection, isolation, and treatment, was analyzed. Among various types of mobile medical facilities, seclusion space was considered suitable for utilizing modular construction methods, as it is the most rational method that can satisfy the environmental level of fixed healthcare facilities' space. Therefore, seclusion modules based on modular construction were planned, consisting of two protective units for stabilizing patients with psychiatric illness, one for treatment unit that can accommodate both internal and external treatment, and another one for an infectious disease isolation unit equipped with negative pressure equipment. Implications: This study analyzed the necessary medical functions of the interior space of the mobile stabilization module based on the spatial analysis of existing medical facilities, and proposed alternative spatial configurations according to treatment, seclusion, isolation functions.

• Journal of Society of Preventive Korean Medicine
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• v.28 no.2
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• pp.19-29
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• 2024

Objective : Pattern identification in Korean Medicine is a core value, leading to a quantitative and qualitative increase in related studies. This study aims to identify trends in newly published research and discuss pattern identification. Method : We reviewed studies from 2015 to 2023 using the Oriental Medicine Advanced Searching Integrated System provided by the Korea Institute of Oriental Medicine. The keywords used were: pattern identification, cold-heat, deficiency-excess, exterior-interior, yin-yang, phlegm-retained fluid, static blood, qi-blood, qi deficiency, blood deficiency, yin deficiency, yang deficiency, and four-constitution. Results : A total of 150 studies met the inclusion criteria. These comprised 84 observational studies, including case reports, 2 experimental studies, and 64 literature reviews. Most studies were published in the Korean Journal of Oriental Physiology and Pathology. On average, 17.1 studies were published annually, although the number of studies has decreased over the years. Network analysis revealed that the main keyword in titles was pattern identification (n=122), followed by study (n=68) and patients (n=34). Conclusion : These findings highlight trends in studies related to pattern identification, with a focus on its standardization. Considering the limitations of pattern identification, a shift towards a disease-centered approach is recommended.

• CELLMED
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• v.5 no.4
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• pp.25.1-25.2
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• 2015

Static blood (SB) is a traditional Korean medicine disease symptom caused by a blood amassment, which refers to a pathological product of blood circulating poorly or accumulating in the interior. The growth and denaturalization of various organizations, inflammatory response and blood circulation disorder are regarded pathological conditions of SB. Endometrial hyperplasia (EH) is a state of excessive proliferation of the cells of the endometrium. Therefore, we suggest the EH mouse model as the experimental animal model of SB.

• Journal of Sasang Constitutional Medicine
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• v.33 no.4
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• pp.23-31
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• 2021

Objective The case report showed that sudden hearing loss and tinnitus after trigeminal schwannoma surgery were improved with Yeoldahansotang-gamibang. Method The patient was diagnosed with Taeeumin interior heat (Ganyeol) disease based on the original symptoms of Taeeumin. He was treated with herbal medicine and acupuncture treatment. Puretone audiometry (PTA), speech audiometry, tinnitus handicap inventory (THI) and the original symptoms were investigated before and after the treatment. Results Right side PTA score was significantly reduced, speech audiometry was improved in speech reception threshold (SRT), word recognition score (WRS) and most comfortable level (MCL) and THI score decreased from 40 to 0, which showed normalizing hearing function. And the patient revealed improvements in sleeping, digestion, stooling, perspiration and facial sensation after treatment. Conclusion This study suggests that Yeoldahansotang-gamibang is effective on sudden hearing loss and tinnitus after surgery by correcting the imbalanced energy of Taeeumin.

• The Journal of Korean Medical History
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• v.35 no.1
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• pp.69-86
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• 2022

This study examined guange (關格) in Yixuerumen (醫學入門) from a new perspective and evaluated its value in terms of emergency medicine. We compared and analyzed the definition, symptoms, and treatment methods of guange in Yixuerumen with related clinical presentations in modern medicine. Guange includes nausea and vomiting, dysphagia, dysuria, and constipation without diarrhea. A representative disease related to dysuria is uremia, while one related to constipation, nausea, and vomiting is enterocleisis, and and a third related to dysphagia is chronic esophagitis and esophagus cancer. Li Chan, the author of Yixuerumen, recognized guange as an emergency of serious eating and elimination disorder as various symptoms of diseases (病症) gradually get worse from the perspective of external diseases (外感病) and miscellaneous diseases (雜病) and handled it in various ways including yin-tonifying medicinals (補陰藥), qi-tonifying medicinals (補氣藥), qi-regulating formulas (理氣劑), phlegm-dispelling formulas (去痰劑), and "water rising, fire falling" formulas (水升火降) in addition to emetic formulas (催吐劑), diuretic formulas (滲利劑), and interior-attacking formula (攻裏劑). Concepts like guange in Yixuerumen were somewhat useful when handling the applicable emergencies at the level of then medical treatment.