Browse > Article
http://dx.doi.org/10.5667/tang.2015.0016

A proposal for an experimental model of the static blood syndrome in the traditional Korean medicine  

Lim, Dahae (Department of Korean Physiology, College of Pharmacy, Kyung Hee University)
Go, Jihyun (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Kang, Sangwoo (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Hong, Sungwei (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Kim, Juok (Department of Korean Pharmaceutical Science, College of Pharmacy, Kyung Hee University)
Yoou, Myoung-schook (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Kim, Na-Rae (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Kim, Hee-Yun (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Park, Chan-Lee (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University)
Publication Information
CELLMED / v.5, no.4, 2015 , pp. 25.1-25.2 More about this Journal
Abstract
Static blood (SB) is a traditional Korean medicine disease symptom caused by a blood amassment, which refers to a pathological product of blood circulating poorly or accumulating in the interior. The growth and denaturalization of various organizations, inflammatory response and blood circulation disorder are regarded pathological conditions of SB. Endometrial hyperplasia (EH) is a state of excessive proliferation of the cells of the endometrium. Therefore, we suggest the EH mouse model as the experimental animal model of SB.
Keywords
static blood; traditional Korean medicine; experimental animal model; endometrial hyperplasia;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Michael HR, Gordon IK, Wojciech P. Histology : A Text and Atlas. 4th ed. (Baltimore, U.S.A; Lippincott Williams & Wilkins), 2002.
2 Nam EJ, Lee YK, Lee DN, Kim HJ. Clinical Study on the Effect of Gyebongnyeong capsule in the Treatment of Primary Dysmenorrhea. Koran J Oriental Physiology & Pathology 2006;20:1364-1368.
3 Park SH, Lee JH, Kim MR, Hwang KJ, Kim HS. Detection of thioredoxin reductase-1 using proteomic analysis in endometrium with endometriosis. Korean Society of Obstetrics Gynecology. 2009;95:94.
4 Yang CH, Almomen A, Wee YS, Jarboe EA, Peterson CM, Janát-Amsbury MM. An estrogen-induced endometrial hyperplasia mouse model recapitulating human disease progression and genetic aberrations. Cancer Med. 2015;4:1039-1050.   DOI
5 Yoon YJ, Cho JH, Jang JB, Lee JM, Lee CH, Lee KS. A study on the Correlation between Primary dysmenorrhea and Blood stasis. The Journal of Oriental Obstetrics & Gynecology. 2009;22:148-160.
6 Lax S. Precursor lesions of endometrial carcinoma: diagnostic approach and molecular pathology. Pathologe. 2011;32:255-264.   DOI
7 Lee SH, Kang MW, Lee H, Lee SY. Effectiveness of Bee-venom Acpuncture and Ouhyul Herbal Acpuncture in Herviation of Nucleus Pulposus-comparison with Acpuncture Therapy Only. The Journal of Korean Acupuncture & Moxibustion Society. 2007;24:197-205.
8 Erdemoglu E, Güney M, Giray SG, Take G, Mungan T. Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia. Eur J Obstet Gynecol Reprod Biol. 2009;145:195-199.   DOI
9 Kim MR, Lee JH, Seo SS, Chang HJ, Hwang KJ, Kim YA, Park DW. Increased Proliferating Activity and Bcl-2 Protein Expression in Eutopic Endometrium with Endometriosis. Korean J Obstet Gynecol. 2005;48:1942-1949.
10 Kim SW, Joo SG, Goo BS. Literatual Study on Cause and Treatment of Amnesia. J of Oriental Neuropsychiatry, 2001;12:69-84.
11 Krstic RV. Human Microscopic Anatomy. 3rd ed. (New York, U.S.A: Springer), pp. 412-13, 1997.