• 제목/요약/키워드: the exponential function

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The Study of Trnascriptional Regulated Gene, $hrp^{2+}$, in Yeast

  • Choi, In-Soon
    • Journal of Life Science
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    • 제11권2호
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    • pp.111-115
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    • 2001
  • This study was designed to clone the SNF2/SW12 helicase-related genes from the fission yeast Schizosaccha-romyces pombe and thereafter to elucidate the common functions of the proteins in this family. The $hrp^{2+}$gene was cloned by polymerase chain reaction amplification using degenerative primers from conserved SNF2 motifs within the ERCC6 gene, which encodes a protein involved in DNA excision repair. Like other SNF2/SW12 family proteins, the deduced amino acid sequence of Hrp2 contains DNA-dependent ATPase/7 helicase domains as well as the chromodomain and the DNA binding domain. This configuration is similar to that of mCHD1 (mouse chromo-ATPase/helicase-DNA-dinding protein 1), suggesting that Hrp2 is a S. pombe homolog of mCHD1, which is thought to function in altering the chromatin structure to control the gene expression. To characterize the function of Hrp2, 4 Uracil-Hrp2 fusion protein, it was purified near homogeneity by affinity chromatography on $Ni^{2+}$-NTA agarose, DEAE-Sepharose ion exchange arid Sephacryl S-200 gel filtration chromatographies. The purified fusion protein exhibited DNA-dependent ATPase activity, which was stimulated by both double-stranded and single-stranded DNA. To determine the steady-state level of $hrp^{2+}$ transcripts during growth, cells were cultured in medium and collected at every 2hr to prepare total RNAs. The northern blot analysis showed that the level of $hrp^{2+}$ transcripts reached its maximum before the cells entered the exponential growth phase and then decreased gradually, This result implies that Hrp2 may be required at early stages of cell growth.h.

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Strengthening of prestressed girder-deck system with partially debonding strand by the use of CFRP or steel plates: Analytical investigation

  • Haoran Ni;Riliang Li;Riyad S. Aboutaha
    • Computers and Concrete
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    • 제31권4호
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    • pp.349-358
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    • 2023
  • This paper describes an in-depth analysis on flexural strength of a girder-deck system experiencing a strand debonding damage with various strengthening systems, based on finite element software ABAQUS. A detailed finite element analysis (FEA) model was developed and verified against the relevant experimental data performed by other researchers. The proposed analytical model showed a good agreement with experimental data. Based on the verified FE model, over a hundred girder-deck systems were investigated with the consideration of following variables: 1) debonding level, 2) span-to-depth ratio (L/d), 3) strengthening type, 4) strengthening material thickness. Based on the data above, a new detailed analytical model was developed and proposed for estimating residual flexural strength of the strand-debonding damaged girder-deck system with strengthening systems. It was demonstrated that both finite element model and analysis model could be used to predict flexural behaviors for debonding damaged prestressed girder-deck systems. Since the strands are debonding from surrounding concrete over a certain zone over the length of the beam, the increase of strain in strands can be linked with a ratio ψ, which is Lp/c. The analytical model was proposed and developed regarding the ratio ψ. By conducting procedure of calculating ψ, the ψ value varies from 9.3 to 70.1. Multiple nonlinear regression analysis was performed in Software IBM SPSS Statistics 27.0.1 to derive equation of ψ. ψ equation was curved to be an exponential function, and the independent variable (X) is a linear function in terms of three variables of debonding level (λ), span length (L), and amount of strengthening material (As). The coefficient of determinate (R2) for curve fitting in nonlinear regression analysis is 0.8768. The developed analytical model was compared to the ultimate capacities computed by FEA model.

Remaining life prediction of concrete structural components accounting for tension softening and size effects under fatigue loading

  • Murthy, A. Rama Chandra;Palani, G.S.;Iyer, Nagesh R.
    • Structural Engineering and Mechanics
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    • 제32권3호
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    • pp.459-475
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    • 2009
  • This paper presents analytical methodologies for remaining life prediction of plain concrete structural components considering tension softening and size effects. Non-linear fracture mechanics principles (NLFM) have been used for crack growth analysis and remaining life prediction. Various tension softening models such as linear, bi-linear, tri-linear, exponential and power curve have been presented with appropriate expressions. Size effect has been accounted for by modifying the Paris law, leading to a size adjusted Paris law, which gives crack length increment per cycle as a power function of the amplitude of a size adjusted stress intensity factor (SIF). Details of tension softening effects and size effect in the computation of SIF and remaining life prediction have been presented. Numerical studies have been conducted on three point bending concrete beams under constant amplitude loading. The predicted remaining life values with the combination of tension softening & size effects are in close agreement with the corresponding experimental values available in the literature for all the tension softening models.

변형 커버리지 함수를 고려한 ENHPP 소프트웨어 신뢰성장 모형에 관한 비교 연구 (The Comparative Study for ENHPP Software Reliability Growth Model based on Modified Coverage Function)

  • 김희철;김평구
    • 한국컴퓨터정보학회논문지
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    • 제12권6호
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    • pp.89-96
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    • 2007
  • 유한고장수를 가진 비동질적인 포아송 과정에 기초한 모형들에서 잔존 오류 1개당 고장 발생률은 일반적으로 상수, 혹은 단조증가 및 단조 감소 추세를 가지고 있다. 소프트웨어 제품의 정확한 인도시기를 예측하거나 효용성 및 신뢰성을 예측하기 위해서는 소프트웨어 테스팅 과정에서 중요한 요소인 테스트 커버리지를 이용하면 보다 효율적인 테스팅 작업을 할 수 있다. 본 논문에서는 기존의 소프트웨어 신뢰성 모형인 지수 커버리지 모형과 S-커버리지 모형을 적용하고 이 분야에 적용 될 수 있는 변형 커버리지 모형(중첩모형 및 혼합모형) 비교 문제를 제안하였다. 고장 간격시간으로 구성된 자료를 이용한 모수추정 방법은 최우추정법과 수치해석 방법인 이분법을 사용하여 모수 추정을 실시하고 효율적인 모형 선택은 편차자승합(SSE)을 이용하였다.

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생태네트워크와 접근성 분석에 의한 서울시 미집행 도시공원의 보전 우선순위 평가 (Assessing conservation priorities of unexecuted urban parks in Seoul using ecological network and accessibility analyses)

  • 강완모;송영근;성현찬;이동근
    • 한국환경복원기술학회지
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    • 제21권2호
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    • pp.53-64
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    • 2018
  • This study aims to quantitatively evaluate the conservation priorities of unexecuted urban parks in Seoul both from an ecological and public perspective. To this end, two methodologies, ecological network analysis based on graph and circuit theory and accessibility analysis, were employed in order to assess ecological connectivity of and public accessibility to unexecuted parks, respectively. This study applied linkage-mapping methods (shortest path and current flow betweenness centrality) of connectivity analysis to an integrated map of landscape permeability. The population-weighted accessibility to unexecuted parks was measured based on a negative exponential distance decay function. As a result, for both ecological connectivity and accessibility, Gwanaksan, Suraksan, and Bulamsan urban natural parks are found to be the most important (rank 1-3) to be conserved. For these sites, inner park areas with conservation priorities for connectivity and accessibility were identified. The findings of the study can be used for giving conservation priority to the unexecuted urban parks in terms of long-term sustainable urban planning.

The Distribution Characteristics of Polychlorinated Biphenyls in Rural Atmosphere

  • Yeo, Hyun-Gu;Park, Minkyu;Chun, Man-Young;Young Sunwoo
    • Journal of Korean Society for Atmospheric Environment
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    • 제18권E3호
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    • pp.143-151
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    • 2002
  • Atmospheric concentrations of polychlorinated biphenyl (PCB) congeners were measured every two weeks from July, 1999 to January, 2000 at Hankyong University in Ansung, Kyounggi-do. Atmospheric concentrations of ∑$_{24}$PCB showed a range of 19.8~71.9 pg/m3. The highest concentration of PCB homolog was tri-CBs (sum of PCB 18, 27, 28, 33, 38) which had a comparatively higher vapor pressure than other homologs. The contribution ratio of lighter PCB homologs (tri-CBs) to total PCBs was 44.5%, and these homologs were the main components of PCBs. The ratio PCB homologs/deca-CB (PCB 209) suggested that the contribution of vapor phase PCBs increased greatly in summer relative to other seasons. In addition, the regression lines for PCB homologs/deca-CB (PCB 209) and temperature ($^{\circ}C$) appeared as an exponential function with high correlation (R2>0.67, p< 0.01). This suggests that the concentration of vapor phase PCB homologs increases steeply with increasing temperature.

Probabilistic Analysis of Drought Characteristics in Pakistan Using a Bivariate Copula Model

  • Jehanzaib, Muhammad;Kim, Ji Eun;Park, Ji Yeon;Kim, Tae-Woong
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2019년도 학술발표회
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    • pp.151-151
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    • 2019
  • Because drought is a complex and stochastic phenomenon in nature, statistical approaches for drought assessment receive great attention for water resource planning and management. Generally drought characteristics such as severity, duration and intensity are modelled separately. This study aims to develop a relationship between drought characteristics using a bivariate copula model. To achieve the objective, we calculated the Standardized Precipitation Index (SPI) using rainfall data at 6 rain gauge stations for the period of 1961-1999 in Jehlum River Basin, Pakistan, and investigated the drought characteristics. Since there is a significant correlation between drought severity and duration, they are usually modeled using different marginal distributions and joint distribution function. Using exponential distribution for drought severity and log-logistic distribution for drought duration, the Galambos copula was recognized as best copula to model joint distribution of drought severity and duration based on the KS-statistic. Various return periods of drought were calculated to identify time interval of repeated drought events. The result of this study can provide useful information for effective water resource management and shows superiority against univariate drought analysis.

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장기 저장되는 일회성 시스템의 수명 관리 프로그램에 대한 연구 (A Study on Shelf-life Management Program of Long-term Storage One-shot System)

  • 박동인;심행근
    • 한국산학기술학회논문지
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    • 제21권1호
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    • pp.628-633
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    • 2020
  • 본 논문에서는 일회성 시스템이 장기 저장되는 동안 수명을 관리하기 위한 프로그램에 대해 연구하였다. 일회성 시스템은 주로 장기간 저장 또는 비운용 상태로 유지되다 임무수행시 일회성으로 운용되는 특징이 있으며, 일회성에 해당하는 기능은 주로 화약과 같은 시효성 품목을 통해 발휘된다. 이러한 시효성 품목은 저장 기간이 경과됨에 따라 성능과 특성이 변화하는 품목으로서 장기 저장간 정상 상태를 유지하기 위한 수명 관리가 매우 중요하며, 체계적인 수명 관리를 위해서는 관리 기준 설정이 필요하다. 수명 관리 기준과 현재 신뢰도를 비교하여 수명연장을 결정하며, 차기 수명평가 시기를 결정하는 방법을 지수분포와 와이블분포별로 제시한다. 수명평가 결과 시험데이터를 지속적으로 누적하며 수명분포의 모수를 최신화하고 신뢰도 변화를 확인하여, 수명을 연장하거나 만료를 판정한다. 또한, 일회성 시스템인 K000 신관의 ASRP 시험데이터를 활용하여 제안된 수명 관리 프로그램에 따라 수명 관리가 어떻게 이뤄지게 되는지 적용 가능성을 확인하였다.

접지된 다층 유전체위의 저항띠 격자구조에 의한 TE 산란의 해 (Solution of TE Scattering by a Resistive Strip Grating Over Grounded Dielectric Multilayers)

  • 윤의중
    • 한국통신학회논문지
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    • 제31권9A호
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    • pp.913-919
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    • 2006
  • 본 논문에서는 스트립 폭과 격자주기, 비유전율, 유전체 층의 두께, 그리고 TE(transverse electric) 평면파의 입사각에 따른 접지된 다층 유전체위의 저항띠 격자구조에 의한 TE 산란 문제를 수치해석 방법인 FGMM(Fourier-Galerkin Moment Method)을 이용하여 해석하였다. 유도되는 표면전류밀도는 간단한 함수인 지수함수를 사용하여 Fourier 급수로 전개하였다. 전반적으로 다층유전체의 비유전율과 두께가 증가함에 따라 반사전력이 증가하였고, 반사전력의 급변점들은 공진효과에 기인한 것으로 과거에 wood's anomallies$^{[7]}$라고 불리워졌다. 제안된 방법의 검증을 위하여 기존의 완전도체 경우인 균일 저항율 R = 0에 대한 정규화된 반사전력의 수치결과는 기존 논문들과 일치하였다.

접지된 유전체 평면위의 저항띠 격자구조에 의한 TE 산란 해석 (Analysis of the TE Scattering by a Resistive Strip Grating Over a Grounded Dielectric Plane)

  • 윤의중
    • 한국항행학회논문지
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    • 제10권3호
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    • pp.198-204
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    • 2006
  • 본 논문에서는 스트립 폭과 격자주기, 유전체 층의 비유전율과 두께, 그리고 TE(transverse electric) 평면파의 입사각에 따른 접지된 유전체 평면위의 저항띠 격자구조에 의한 TE 산란 문제를 수치해석 방법인 FGMM(Fourier-Galerkin Moment Method)를 이용하여 해석하였다. 유도되는 표면전류밀도는 간단한 함수인 지수 함수를 사용하여 Fourier 급수로 전개하였다. 유전체층의 비유전율과 두께가 증가함에 따라 반사전력이 증가하였고, 반사전력의 급변점들은 공진효과에 기인한 것으로 과거에 wood's anomallies[7]라고 불리워졌다. 제안된 방법의 검증을 위하여 기존의 완전도체 경우인 균일 저항율 R = 0에 대한 정규화된 반사전력의 수치결과는 기존의 논문들과 일치하였다.

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