• 제목/요약/키워드: the end of Chosun

검색결과 258건 처리시간 0.028초

Preparation and Characterization of Piroxicam/Poloxamer Solid Dispersion Prepared by Melting Method and Solvent Method

  • Yu, Hang;Chun, Myung-Kwan;Choi, Hoo-Kyun
    • Journal of Pharmaceutical Investigation
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    • 제37권1호
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    • pp.1-5
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    • 2007
  • Solid dispersions of piroxicam were prepared by melting method using poloxamer as a carrier. The results of DSC and XRD studies showed that the amorphous farm of piroxicam coexisted with the crystalline form in the solid dispersions. However, the ratio of crystalline form of piroxicam in the solid dispersion prepared by melting method decreased in comparison with the same ratio of the solid dispersion prepared by solvent method. As the ratio of poloxamer in the solid dispersion increased, the ratio of the amorphous form of piroxicam in the solid dispersion increased. The dissolution rate of piroxicam from the solid dispersions was significantly higher than that from piroxicam powder. In comparison to the solid dispersion prepared by solvent method, the dissolution rate of piroxicam from the solid dispersion prepared by melting method was higher. As the ratio of poloxamer in the solid dispersion prepared by melting method increased, the initial dissolution rate decreased, however, the total amount dissolved at the end of the study increased.

입자상물질의 광학밀도 및 농도측정에 적용된 저가형 광학 부품의 성능평가 (Performance Evaluation of Low-cost Optical Components used for Measuring the Optical Density and Concentration of Particulate Matter(PM))

  • 백영조;홍터기;황철홍;박설현
    • 한국안전학회지
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    • 제31권5호
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    • pp.1-6
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    • 2016
  • The performance of a set of low-cost optical components used for measuring the optical density of PM particles was evaluated in the present study. To this end, the set of low-cost optical components was replaced with that of general optical components used to measure the PM optical density under identical experimental conditions. The optical densities measured from the set of general optical components were then compared to those obtained from the set of low-cost optical components. While the optical density is measured, another key parameter, the dimensionless extinction constant of PM particles (which is needed to optically measure the PM concentration) was also determined in the present study. The experimental results indicate that the optical density and PM concentration measurements performed by low-cost optical components are feasible, producing trackable variations in the OD and concentrations compared to values obtained from the set of general optical components.

A study on pressurizer cutting scenario for radiation dose reduction for workers using VISIPLAN

  • Lee, Hak Yun;Kim, Sun Il;Song, Jong Soon
    • Nuclear Engineering and Technology
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    • 제54권7호
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    • pp.2736-2747
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    • 2022
  • The operations in the design lifecycle of a nuclear power plant targeted to be decommissioned lead to neutron activation. Operations in the decommissioning process include cutting, decontamination, disposal, and processing. Among these, cutting is done close to the target material, and thus workers are exposed to radiation. As there are only a few studies on pressurizers, there arises the need for further research to assess the radiation exposure dose. This study obtained the specifications of the AP1000 pressurizer of Westinghouse and the distribution of radionuclide inventory of a pressurizer in a pressurised water reactor for evaluation based on literature studies. A cutting scenario was created to develop an optimal method so that the cut pieces fill a radioactive solid waste drum with dimensions 0.571 m × 0.834 m. The estimated exposure dose, estimated using the tool VISIPLAN SW, in terms of the decontamination factor (DF) ranged from DF-0 to DF-100, indicating that DF-90 and DF-100 meet the ICRP recommendation on exposure dose 0.0057 mSv/h. At the end of the study, although flame cutting was considered the most efficient method in terms of cutting speed, laser cutting was the most reasonable one in terms of the financial aspects and secondary waste.

Companies Entering the Metabus Industry - Major Big Data Protection with Remote-based Hard Disk Memory Analysis Audit (AUDIT) System

  • Kang, Yoo seok;Kim, Soo dong;Seok, Hyeonseon;Lee, Jae cheol;Kwon, Tae young;Bae, Sang hyun;Yoon, Seong do;Jeong, Hyung won
    • 통합자연과학논문집
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    • 제14권4호
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    • pp.189-196
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    • 2021
  • Recently, as a countermeasure for cyber breach attacks and confidential leak incidents on PC hard disk memory storage data of the metaverse industry, it is required when reviewing and developing a remote-based regular/real-time monitoring and analysis security system. The reason for this is that more than 90% of information security leaks occur on edge-end PCs, and tangible and intangible damage, such as an average of 1.20 billion won per metaverse industrial security secret leak (the most important facts and numerical statistics related to 2018 security, 10.2018. the same time as responding to the root of the occurrence of IT WORLD on the 16th, as it becomes the target of malicious code attacks that occur in areas such as the network system web due to interworking integration when building IT infrastructure, Deep-Access-based regular/real-time remote. The concept of memory analysis and audit system is key.

산화제 첨가에 따른 백금 전극 물질의 연마 특성 (Polishing Characteristics of Pt Electrode Materials by Addition of Oxidizer)

  • 고필주;김남훈;이우선
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2006년도 제37회 하계학술대회 논문집 C
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    • pp.1384-1385
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    • 2006
  • Platinum is a candidate of top and bottom electrode in ferroelectric random access memory and dynamic random access memory. High dielectric materials and ferroelectric materials were generally patterned by plasma etching, however, the low etch rate and low etching profile were repoted. We proposed the damascene process of high dielectric materials and ferroelectric materials for patterning process through the chemical mechanical polishing process. At this time, platinum as a top electrode was used for the stopper for the end-point detection as Igarashi model. Therefore, the control of removal rate in platinum chemical mechanical polishing process was required. In this study, an addition of $H_{2}O_{2}$ oxidizer to alumina slurry could control the removal rate of platinum. The removal rate of platinum rapidly increased with an addition of 10wt% $H_{2}O_{2}$ oxidizer from 24.81nm/min to 113.59nm/min. Within-wafer non-uniformity of platinum after chemical mechanical polishing process was 9.93% with an addition of 5wt% $H_{2}O_{2}$ oxidizer.

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Endoscopic Precise 3D Surface Profiler Based on Continuously Scanning Structured Illumination Microscopy

  • Park, Hyo Mi;Joo, Ki-Nam
    • Current Optics and Photonics
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    • 제2권2호
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    • pp.172-178
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    • 2018
  • We propose a precise 3D endoscopic technique for medical and industrial applications. As the 3D measuring principle, the continuously scanning structured illumination microscopy (CSSIM), which enables to obtain 3D sectional images by the synchronous axial scanning of the target with the lateral scanning of the sinusoidal pattern, is adopted. In order to reduce the size of the probe end, the illumination and detection paths of light are designed as coaxial and a coherent imaging fiber bundle is used for transferring the illumination pattern to the target and vice versa. We constructed and experimentally verified the proposed system with a gauge block specimen. As the result, it was confirmed that the 3D surface profile was successfully measured with $16.1{\mu}m$ repeatability for a gauge block specimen. In order to improve the contrast of the sinusoidal illumination pattern reflected off on the target, we used polarizing optical components and confirmed that the visibility of the pattern was suitable in CSSIM.

조선시대(朝鮮時代) 창덕궁(昌德宮) 희정당(熙政堂)의 편전(便殿) 전용(轉用)에 대하여 (On the Huijongdang's Diversion to Pyonjon of the Changduk Palace in the Chosun Dynasty)

  • 김동욱
    • 건축역사연구
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    • 제3권1호
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    • pp.9-22
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    • 1994
  • In Pyonjon, Kings received high-ranked officials, heard preachings of classical literatures. State affairs were also discussed here. In palaces of the Chosun Dynasty, Pyonjon used to be regarded as the most important building second to the main hall. In Changduk palace, Sonjongjon was the original Pyonjon. But, before the end of the 17th century, Huijongdang began to be called Pyonjon, and after the 19th century, Huijongdang became Pyonjon officially. Sonjongjon was located beside the main hall, while Huijongdang before the King's bedroom. The floor of the former building was covered with brick but Huijongdang covered with ondol and wooden floorings. In Sonjongjon, every man sit on the chair, but in Huijongdang King and officials used to sit down on the floor. The fact that Huijongdang became Pyonjon replacing to Sonjongjon meant change of building arrangement in the palace and usage of inner space.

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REAL HYPERSURFACES IN THE COMPLEX HYPERBOLIC QUADRIC WITH CYCLIC PARALLEL STRUCTURE JACOBI OPERATOR

  • Jin Hong Kim;Hyunjin Lee;Young Jin Suh
    • 대한수학회지
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    • 제61권2호
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    • pp.309-339
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    • 2024
  • Let M be a real hypersurface in the complex hyperbolic quadric Qm*, m ≥ 3. The Riemannian curvature tensor field R of M allows us to define a symmetric Jacobi operator with respect to the Reeb vector field ξ, which is called the structure Jacobi operator Rξ = R( · , ξ)ξ ∈ End(TM). On the other hand, in [20], Semmelmann showed that the cyclic parallelism is equivalent to the Killing property regarding any symmetric tensor. Motivated by his result above, in this paper we consider the cyclic parallelism of the structure Jacobi operator Rξ for a real hypersurface M in the complex hyperbolic quadric Qm*. Furthermore, we give a complete classification of Hopf real hypersurfaces in Qm* with such a property.

토끼의 두개골내에 형성된 골결손부에서 $HA/{\beta}-TCP$ composite powders의 골형성에 관한 조직학적 연구 (Bone formation effect of $HA/{\beta}-TCP$ composite powders in rabbit calvarial bone defects;Histologic study)

  • 이광호;장현선;박주철;김흥중;김종관;김병옥
    • Journal of Periodontal and Implant Science
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    • 제36권1호
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    • pp.1-14
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    • 2006
  • The purpose of the present study was to evaluate the histologic results of bone cavities that were surgically created in the calvaria of rabbit and filled with $HA/{\beta}-TCP$ composite powders, which had been developed in Korea (Dentium, Korea). Ten young adult rabbits were used. Four defects were surgically produced in calvaria of each rabbit. Each rabbit was anesthetized with Ketamine-HCI (5 mg/kg, Yuhan Cor. Korea) and Xylazine-HCI (1.5 ml/kg, Yuhan Cor. Korea)). An incision was made to the bony cranium and the periosteum was reflected. Using a trephine bur (external diameter: 8 mm, 3i, USA), 4 'through-and-through' bone defects were created with copious irrigation, and classified into 4 groups: control group: no graft materials, experimental group I: normal saline + graft materials: experimental group II: venous blood + graft materials: experimental group III: graft materials only. The defects were randomly filled with graft materials. The defects were closed with resorbable suture material. At the end of the surgical procedure, all animals received a single intramuscular injection of antibiotics Gentamicin (0.1 mg/kg, Dae Sung Microb. Korea). Rabbits were sacrificed with phentobarbital (100 mg/kg) intravenously at 1-, 2-, 4-, 6- and 8-week after. Specimens were treated with hydrochloric acid decalcifying solution (Fisher Scientific, Tustin, CA) and sectioned by bisecting the 8 mm diameter defects. The histologic specimens were prepared in the general method with H & E staining at 6 ${\mu}m$ in thickness. The results were as follows; 1. New bone formation showed from after 2-week of surgery in defect area. As time lapsed, lots of new bone formation and mature bones showed. 2. Histologically, degree of new bone formation could not be discerned among the experimental groups. But, for experimental group II, lots of cells gathered around graft materials after 1-week of surgery, new bone formed slightly faster and than the others at 1-week after. For experimental group I, a few inflammatory finding showed around graft material at after 1-week and after 2-week of surgery. 3. No bone formation did show for control group. Based on histologic results, the new $HA/{\beta}-TCP$ composite powders appeared to act as a scaffolding material for regeneration of osseous defects.

Antioxidant effect of chitosan in the renal failure

  • Yoon, Hyun-Joong;Kim, Young-Ho;Park, Haeng-Soon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.145.1-145.1
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    • 2003
  • Oxidative stress has been implicated in a range of disease states, including end-stage renal failure treated with hemodialysis [Westhuyzen J. et al, 2003]. Free radicals react with biological molecules and destroy the structure of cells, which eventually causes free-radical induced disease such as cancer, renal failure, aging, etc. Exogenous or endogenously produced nitric oxide (NO) inhibits superoxide-stimulated urea permeability. In the inner medulla, superoxide generation by local oxidases may stimulate urea transport, and the role of endogenous No may be to dampen this effect by decreasing superoxide levels [Zimpelmann J. et al, 2003 (Epub ahead of print)]. (omitted)

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