• Journal of the Korean Society for Library and Information Science
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• v.42 no.4
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• pp.391-415
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• 2008

Gwa-ik Wonjong Gongsin-Nokgwon(佐翼原從功臣錄券) is a book which recorded the titles of position and the names of retainers who made Se-jo into Chosun dynasty's king. This study aims to research into existing 4 books of Gwa-ik Wonjong Gongsin-Nokgwon, which were to analyze the reasons of grant, structure and forms, the characteristics of meritorious retainers' official positions and social status. As the result, Gwa-ik Wonjong Gongsin-Nokgwon is the metal typologic book which was made up Choju-Gapin(初鑄甲寅) letter type. The structure of the Gwa-ik Wonjong Gongsin-Nokgwon was composed of the beginning(卷首) the body(本文) the end(卷末). Gwa-ik Wonjong meritorious retainers formed the total of 2,356 persons(1st grade: 80 persons, 2nd grade: 846 persons, 3rd grade: 1,430 persons) with 295 official titles. Also an analysis of their social status confirmed that 2,265 persons were Yang-ban(兩班) which constituted the largest group, Jung-in(中人) were 71 persons, Chun-in(賤人) were 11 persons and Yang-in(良人) were 9 persons.

• Journal of Korean Library and Information Science Society
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• v.40 no.4
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• pp.427-456
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• 2009

Jwa-lee Wonjong Gongsin-Nokgwon(佐理原從功臣錄券) is a book which recorded the titles of position and the names of retainers who made Sung-jong into Chosun dynasty's king. This study aims to research into existing only 1 books of Jua-ik Wonjong Gongsin-Nokgwon, which were to analyze the reasons of grant, structure and forms, the characteristics of meritorious retainers' official positions and social status. As the result, Jwa-lee Wonjong Gongsin-Nokgwon is the metal typologic book which was made up Eul-hae(乙亥) letter type. The structure of the Jwa-lee Wonjong Gongsin-Nokgwon was composed of the beginning(卷首) the body(本文) the end(卷末). Jwa-lee Wonjong meritorious retainers formed the total of 1,059 persons(1st grade : 64 persons, 2nd grade : 272 persons, 3rd grade : 723 persons) with 513 official titles. Also an analysis of their family name confirmed that 1,059 persons were "Lee" which constituted the largest group(21%), "Kim" were second group(15%).

• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.74-80
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• 2011

Population pharmacokinetics for gentamicin were compared with 20 Korean patients (14 male and 6 female) and 25 Caucasian appendicitis patients (16 male and 9 female). Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope(KS) of the relationship between K versus creatinine clearance(Ccr), the apparent volume of distribution (V), the slope(VS) of the relationship between V versus weight, gentamicin clearance(CL) and the slope(CS) of the relationship between CL versus Ccr and the V. The output includes two marginal probability density function(PDF), means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were$0.402{\pm}0.129hr^{-1}$ ($0.00486{\pm}0.00197[hr{\cdot}mL/min/1.73m^2]^{-1}$) and $0.425{\pm}0.137hr^{-1}$($0.00432{\pm}0.00168[hr{\cdot}mL/min/1.73m^2]^{-1}$) for Korean and Caucasian populations, respectively. The mean V(VS) were not different at $14.3{\pm}3.69L$($0.241{\pm}0.0511L/kg$) and $15.8{\pm}4.81L$($0.236{\pm}0.0531L/kg$) for Korean and Caucasian populations, respectively (P>0.2). The mean CL(CS) were $5.68{\pm}1.69L/hr$ ($0.0714{\pm}0.0222L/kg[hr{\cdot}mL/min/1.73m^2]$) and $6.29{\pm}1.84L/hr$ ($0.0629{\pm}0.0189L/kg[hr{\cdot}mL/min/1.73m^2]$) for Korean and Caucasian populations, respectively. There are no differences in gentamicin pharmacokinetics between Korean and Caucasian appendicitis patients.

• YAKHAK HOEJI
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• v.56 no.1
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• pp.48-54
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• 2012

Enviromental differences in gentamicin pharmacokinetics by using population pharmacokinetic methods were compared with 20 Korean patients and 24 Korean-American appendicitis patients. Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum (NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant (K), the slope (KS) of the relationship between K versus creatinine clearance ($C_{cr}$), the apparent volume of distribution (V), the slope (VS) of the relationship between V versus weight, gentamicin clearance (CL) and the slope (CS) of the relationship between CL versus $C_{cr}$ and the V. The output includes two marginal probability density function (PDF), means, medians, modes, variance and CV%. The mean K (KS) were $0.402{\pm}0.129\;h^{-1}(0.00486{\pm}0.00197\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ and $0.411{\pm}0.135\;h^{-1}(0.00475{\pm}0.00180\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ for Korean and Korean-American populations, respectively. The mean V (VS) were not different at $14.3{\pm}3.6l(0.241{\pm}0.0511l/kg)$ and $15.1{\pm}3.84l(0.239{\pm}0.0492l/kg)$ for Korean and Korean-American populations, respectively (p>0.2). The mean CL (CS) were $5.68{\pm}1.69l/h(0.0714{\pm}0.0222l/kg[h{\cdot}ml/min/1.73\;m^2])$ and $5.70{\pm}1.77l/h(0.0701{\pm}0.0215l/kg[h{\cdot}ml/min/1.73\;m^2])$ for Korean and Korean-American populations, respectively. There were no enviromental differences in gentamicin pharmacokinetics between Korean and Korean-American appendicitis patients.

• Journal of the Korea Concrete Institute
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• v.22 no.1
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• pp.103-111
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• 2010

An efficient design concept for earthquake loads, which is called performance based design, has been standard design in USA, Europe and Japan since those countries experienced severe earthquake damage at end of 90's. For general design, struttie model well predicts the strength of the disturbed region, however, it does not provide ductility information at the failure. Therefore, simple tools which are able to predict both the strength and the ductility of RC structures are in demand. 2D lattice model is introduced in this study as an analysis tool for the RC structures subject to earthquake. Experimental correlation studies indicate the 2D lattice model quite well predict the strength as well as the ductility of RC structures.

• Fire Science and Engineering
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• v.30 no.1
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• pp.37-42
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• 2016

The dimensionless extinction constants of smoke particles produced from burning of soy methyl ester (B100) biodiesel and ultra low sulfur diesel (ULSD) fuels were measured. To this end, optical measurements of smoke volume fraction with the aid of a He-Ne laser at 633 nm were compared to the simultaneous gravimetric measurements. The average value of measured dimensionless extinction constants at 633 nm was 11.8 for biodiesel smoke particles and 11.1 for diesel smoke particles, respectively whose values are very comparable withing the range of measurement uncertainty (${\pm}10.1%$). The analysis of Raman spectroscopy revealed that overall characteristics of light extinction between particles produced from each fuel may differ from each other.

• Communications of Mathematical Education
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• v.24 no.3
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• pp.745-776
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• 2010

In this research, cases of classes for enhancing mathematical creativity are examined in order to explore how to improve methods of math instructions. The objective of the research is to design a creative, efficient math class of superior quality, supplementing the current educational curricula. To this end, features and elements of creative math class are classified into three categories: assignment characteristics, teacher's role, and teaching environment. Based on these, two high school teachers were selected for case study of creative instructions. By observing and analyzing their classes, the research identified main elements of creative classes and their characteristics according to the three categories. The research also explored how to revitalize creative math class by eliciting opinions of researchers and educational experts.

• Journal of Korean Biological Nursing Science
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• v.1 no.1
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• pp.100-114
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• 1999

This study was done to investigate the effects of rapidly-rotating shift work of two-day interval on fatigue level and the concentration of urinary 17-KS, $Na^+,\;Cl^-$. The subjects were 20 nursing college students(control group) and 15 nurses in a university hospital and the study was done from Apr. 21 to May 4th, 1999. In the test group, each 5 nurses were allocated to day shift(8 AM-4 PM), evening shift(4 PM-12 MN) and night shift(12 MN-8 AM) respectively. The fatigue level were measured 30 minutes after work start on the 2nd day of work shift. Urine specimens were collected at 8 AM, 4 PM and 12 MN on the 2nd day of work shift in the control group and 30 minutes before and after work on the 2nd day of work shift in the test group. The data were analyzed with SPSS(for Window, ver 7.5). Statistical analysis was performed by using t-test, paired t-test and ANOVA. The results were as follows. 1. The perceived fatigue level in shift work 1) The physical and mental fatigue level were significantly higher in night shift than that in day or evening shift(p<0.05). In the neuro-sensory fatigue level, night shift showed higher tendency than that in day or evening shift, but there were no significant differences between each shifts. 2) Comparison between the control group and the test group: Physical fatigue level was significantly higher in night shift than that in day or evening shift of the control group(P<.001). Mental fatigue level was significantly higher in day or night shift than that in evening shift of the control group(P<.05). In the neuro-sensory fatigue level, test group showed higher tendency than that in the control group, but there were no significant differences between two groups. 3) The total fatigue level was higher in night shift than that in day shift or evening shift(P<.05). In comparing with the control group, night shift and day shift showed higher total fatigue level than that in the control group(p<0.05). 2. The concentration of urinary 17-KS, $Na^+$ and $Cl^-$ In the control group, urinary 17-KS, $Na^+$ and $Cl^-$ showed higher level in afternoon that in morning and night. In the test group, cr in day and evening shift and $Na^+$ in evening shift showed higher level at the end of work. The 17-KS concentration at the begining and the end of work in three shift groups were lower than those in control group(p<0.05), however, $Cl^-$ concentration at the begining of work in day shift, and the end of work in day and evening shift were higher than those in control group(p<0.05). $Cl^-$ concentration at the begining and end of work in night shift were considerably higher than those in control group repectively(p<0.1, p<001). $Na^+$ concentration showed a higher tendency in three shift groups except at the begining of work in night shift, but there were no statistical difference. In comparing concentration of the 17-KS, $Na^+$ and $Cl^-$ among the shift groups, 17-KS concentration showed a lower tendency and $Na^+,\;Cl^-$ showed a higher tendency in night shift: The result of this study showes that biorhythm of shift work nurse was irregular. Fatigue level as the subjective index for evaluating the health problem concerning shift work was higher in night shift and proved to be in accordance with the concentration of urinary 17-KS, $Na^+$ and $Cl^-$ used as objective indices. Disturbation of biorhythm and work stress due to night shift seems to cause the health problem of nurses and decrease of work efficiency. It is considered that work regualtion is necessary for the rational management of the nursing administration.

• Korean Journal of Optics and Photonics
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• v.27 no.5
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• pp.165-173
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• 2016

In this paper, we propose a three-dimensional (3D) scanning system based on two line lasers. This system uses two line lasers with different wavelengths as light sources. 532-nm and 630-nm line lasers can compensate for missing scan data generated by geometrical occlusion. It also can classify two laser planes by using the red and green channels. For automatic registration of scanning data, we control a stepping motor and divide the motor's rotational degree of freedom into micro-steps. To this end, we design a control printed circuit board for the laser and stepping motor, and use an image processing board. To compute a 3D point cloud, we obtain 200 and 400 images with laser lines and segment lines on the images at different degrees of rotation. The segmented lines are thinned for one-to-one matching of an image pixel with a 3D point.

• Korean Journal of Microbiology
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• v.52 no.3
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• pp.278-285
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• 2016

The bifunctional PheA protein, having chorismate mutase and prephenate dehydratase (CMPD) activities, is one of the key regulatory enzymes in the aromatic amino acid biosynthesis in Escherichia coli, and is negatively regulated by an end-product, phenyalanine. Therefore, PheA protein has been thought as useful for protein engineering to utilize mass production of essential amino acid phenylalanine. To obtain feedback resistant PheA protein against phenylalanine, we mutated by using random mutagenesis, extensively screened, and obtained $pheA^{FBR}$ gene encoding a feedback resistant PheA protein. The mutant PheA protein contains substitution of Leu to Phe at the position of 118, displaying that higher affinity (about $290{\mu}M$) for prephenate in comparison with that (about $850{\mu}M$) of wild type PheA protein. Kinetic analysis showed that the saturation curve of $PheA^{FBR}$ against phenyalanine is hyperbolic rather than that of $PheA^{WT}$, which is sigmoidal, indicating that the L118F mutant enzyme has no cooperative effects in prephenate binding in the presence of phenylalanine. In vitro enzymatic assay showed that the mutant protein exhibited increased activity by above 3.5 folds compared to the wild type enzyme. Moreover, L118F mutant protein appeared insensitive to feedback inhibition with keeping 40% of enzymatic activity even in the presence of 10 mM phenylalanine at which the activity of wild type $PheA^{WT}$ was not observed. The substitution of Leu to Phe in CMPD may induce significant conformational change for this enzyme to acquire feedback resistance to end-product of the pathway by modulating kinetic properties.