• Title/Summary/Keyword: the effect of multiple roles

Search Result 89, Processing Time 0.031 seconds

Effect of Capsaicin on Delayed Rectifier $K^+$ Current in Adult Rat Dorsal Root Ganglion Neurons

  • Hahn, Jung-Hyun;Chung, Sung-Kwon;Bang, Hyo-Weon
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.4 no.1
    • /
    • pp.9-14
    • /
    • 2000
  • $K^+$ currents play multiple roles in the excitability of dorsal root ganglion (DRG) neurons. Influences on these currents change the shape of the action potential, its firing threshold and the resting membrane potential. In this study, whole cell configuration of patch clamp technique had been applied to record the blocking effect of capsaicin, a lipophilic alkaloid, on the delayed rectifier $K^+$ current in cultured small diameter DRG neurons of adult rat. Capsaicin reduced the amplitude of $K^+$ current in dose dependent manner, and the concentration-dependence curve was well described by the Hill equation with $K_D$ value of $19.1{\mu}M.$ The blocking effect of capsaicin was reversible. Capsaicin $(10 {\mu}M)$ shifted the steady-state inactivation curve in the hyperpolarizing direction by about 15 mV and increased the rate of inactivation. The voltage dependence of activation was not affected by capsaicin. These multiple effects of capsaicin may suggest that capsaicin bind to the region of $K^+$ channel, participating in inactivation process.

  • PDF

The Impacts of Threat Emotions and Price on Indonesians' Smartphone Purchasing Decisions

  • PRADANA, Mahir;WISNU, Aditya
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.8 no.2
    • /
    • pp.1017-1023
    • /
    • 2021
  • This research aims to determine the effect of customers' threat emotion and price on the decision to purchase a certain smartphone product. This study uses a quantitative method with a type of descriptive and causal research. It employs non-probability sampling with purposive sampling, with 385 respondents to answer the questionnaires. Data analysis techniques used descriptive analysis and multiple linear regression analysis. Based on the results of descriptive analysis of emotion, price and purchasing decisions are in sync with each other. The results of multiple linear regression analysis techniques indicate the threat emotion and brand trust are influential against the positive decision to purchase smartphone products. The magnitude of the influence of emotions and price have simultaneous effect on purchasing decisions and other decision variables, which are not included in this study, also play minor role in determining purchase intention, such as product quality, brand image and others. Partially, threat emotion and brand trust have a positive effect toward purchasing decisions. The magnitude of the highest influence was the one of price, then followed by emotional threats. The findings of this study suggest that psychological and behavioral effects also play important roles in determining customers' purchase decision.

Regional Relative Price Disparities and Their Driving Forces

  • Chang, Eu Joon;Kim, Young Se
    • East Asian Economic Review
    • /
    • v.21 no.3
    • /
    • pp.201-230
    • /
    • 2017
  • This paper studies the long-run behavior of relative price dispersion among cities in Korea with a special emphasis on heterogeneous transitional patterns of price level dynamics. Formal statistical tests indicate considerable evidence for rejecting the null of relative price level convergence among the majority of cities over the sample period of 1985-2015. The analysis of gravity model suggests that the effect of transportation costs on intercity price level differentials is limited, while other socioeconomic factors, such as income, input factor prices, demographic structure, and housing price growth, play key roles in accounting for persistent regional price level disparities. Individual price levels are found to be better explained by a multiple-component model, and the deviations from PPP may be attributed to distinct stochastic common trends that are characterized by income and demographic structure.

The Structural Path Model of Adolescents′ Internet Addiction and Expected Self-Control (청소년의 인터넷 중독현상과 자기통제기대의 구조적 경로모형에 관한 연구)

  • 박재성
    • Korean Journal of Health Education and Promotion
    • /
    • v.21 no.3
    • /
    • pp.1-17
    • /
    • 2004
  • The purpose of this study is to evaluate the roles of expected self-control and expected self-control results in explaining adolescents' Internet addiction. In the study model, expectations of self-control and self-control results directly determine Internet addiction and Internet use time meditates the impacts of expectations of self-control and self-control results on Internet addiction. The study subjects are 1,080 middle and high school students in Busan. Stratified cluster sampling is applied by school type and school year. The response rate is 96%(l,037cases). This study develops the scales of expected self-control and expected self-control results. The scales of Internet addiction are devised by using the concept of functional dependency such as salience, withdrawal symptoms, mood modification, tolerance, relapse, and conflict. For verifying the study model, path analysis and multiple regression models are applied for identifying path significants and evaluating confounding effects of control variables, respectively. Moreover, multi partial F-test is performed for selecting the best regression model. Expected self-control is a significant determinant of Internet addiction and Internet use time that also significantly explains Internet addiction. The total effect of expected self-control towards Internet addiction is -.95. The total effect is comprised with the direct effect (-.71) and the indirect effect(-.24). In this result, the direct effect refers a curative effect since expected self-control directly reduces the level of Internet addiction, and the indirect effect refers a preventive effect because self-control can reduce time of Internet use that is a direct determinant of Internet addiction. In the test of the confounding effects of control variables, there are no confounding effects in the models of multiple regression. It implies a robustness of the study model as regards control variables. In conclusion, improving adolescents' expected self-control can control Internet addiction level. This finding implies that a health promotion program for improving expected self-control can be a cost effective method compared to other approaches.

The Effect of Paternal Involvement on the Self-Esteem in Early Adolescence (아버지의 양육참여 실태 및 청소년의 자아존중감에 대한 아버지 양육참여의 영향)

  • Kim, Hee Hwa
    • Korean Journal of Child Studies
    • /
    • v.26 no.5
    • /
    • pp.311-330
    • /
    • 2005
  • The purpose of this study was to examine the paternal involvement tendency and its effect on adolescent's self-esteem for boys and girls. Subjects were 607 1st and 2nd grade middle school students in Busan. The data were analyzed by t-test, one-way Anova, Pearson's correlation, and multiple regression analysis. The results were as follows. The scores on paternal involvement were influenced by the amount of time spent with parents, 5days work a week of father, flexibility of leaving work-time of mother, regularity of holiday work of mother as well as adolescents' and fathers' sociodemographic characteristic. For boys, self-esteem was influenced by all sub-scales of paternal involvement : the leisure-life, proffering information, academic support, eveηday life, material support, discipline, and tradition-inheritance. For girls, self-esteem was influenced by leisure-life, proffering information, academic support, everyday life, and material supports.

  • PDF

The Relationship between Toddlers' Negative Emotionality and Mothers' Parenting Stress: The Moderating Roles of Husbands' Cooperation, Mother-Teacher Partnership, and Other Social Support (걸음마기 아동의 부정적 정서성과 어머니의 양육스트레스 간 관계: 남편 및 보육교사의 협력과 주위도움의 조절효과)

  • Park, Hyeon Ju;Kim, Hee Jung;Ahn, Sun Hee
    • Journal of Families and Better Life
    • /
    • v.34 no.6
    • /
    • pp.55-67
    • /
    • 2016
  • The purpose of this study was to examine the relationship between Toddlers'negative emotionality and mothers' parenting stress and the moderating roles of a husbands'cooperation, mother-teacher partnership, and other social support. The participants of this study were 248 mothers with toddlers aged 24-35 months. The method of research used was the questionnaire method. The collected data were mainly analyzed by descriptive statistics, t-test, one-way ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation and multiple regression analysis. The main results of this study were as follows. First, there were differences in mother's parenting stress according to individual characteristics such as mothers employment status, parenting costs, mother's feeling of pregnancy. Second, a moderator effect of a husbands' cooperation was found in the relationship between toddlers'negative emotionality and mothers' parenting stress. Therefore, it was confirmed that husband's cooperation is more of an important factor in nursing children with negative emotions than other support systems.

The effects of a chronic disease/disability and stress from health on depressive symptoms among one-person households: A focus on the moderating effect of social support (1인 가구의 만성질환 및 장애여부, 건강 스트레스와 우울감과의 관계: 사회적 지지 조절효과를 중심으로)

  • Chung, Hyeeun
    • Human Ecology Research
    • /
    • v.57 no.2
    • /
    • pp.201-211
    • /
    • 2019
  • This study examines the effects of chronic disease/disability and stress from health on depressive symptoms among one-person households living in Seoul and Gyeonggi Province in Korea. This study also investigates the moderating effect of social support on the relationship between 1)having a chronic disease/disability and depressive symptoms as well as 2)stress from health and depressive symptoms. This study used data from an online survey targeting one-person households living in Seoul and Gyeonggi Province. The final sample included 499 one-person households. Using a multiple regression analysis with SPSS 20.0, results showed that having a chronic disease/disability was associated with a higher level of depressive symptoms. In addition, stress from health was associated with a higher level of depressive symptoms. In regard to the roles of social support, economic support and emotional support had a direct negative effect on depressive symptoms. Emotional support had a moderating effect on the relationship between having a chronic disease/disability and depressive symptoms. In addition, emotional support also had a moderating effect on the relationship between stress from health and depressive symptoms. Based on these findings, this study suggests that policy makers should reduce the economic burden from a chronic disease/disability and help one-person households to strengthen their social support network.

An Exploratory Research on Moderate Effect of Supply Chain CSR and Co-Existence Activities to Relations Between Supplier Development and Performances (공급업체 개발 활동과 성과에 대한 공급사슬 CSR 및 상생협력의 조절 효과에 대한 탐색적 연구)

  • Park, Jeong Soo;Chang, Deok Shin;Kim, Youn Sung
    • Journal of Korean Society for Quality Management
    • /
    • v.41 no.1
    • /
    • pp.39-52
    • /
    • 2013
  • Purpose: The purpose of this study was to investigate if purchasing companies' efforts of supplier development activities to supplier companies have positive impacts on the purchasing companies' performance as the first step. In the second step, we tried to confirm if the concept of Supply Chain Corporate Social Responsibility activities and Coexistence activities take the roles of moderate variable on relationship between supplier development and three performances respectively. Methods: The collected data through survey were analysed using multiple regression for the first step of the study and moderate regression for the second one of it. Results: The results of this study are as follows; supplier development efforts effect on all three performances positively. Moreover, Supply Chain CSR has significant moderate effect on relationship between supplier management and corporate performances, while Coexistence does between supplier management and logistics performances. In the case of relationship between supplier management and production performances, both Supply Chain CSR and Coexistence show significant moderate effect. Conclusion: Manufacturing companies in Korea need to make effort of supplier development in selective way when they want to practice Supply Chain CSR and Coexistence concurrently considering strategies and objectives.

The effect of Multiple Positions in the Board on the Quality of Internal Accounting Control System (이사의 겸임이 내부회계관리제도의 품질에 미치는 영향)

  • Jung, Woo-Sung
    • Journal of the Korea Convergence Society
    • /
    • v.13 no.1
    • /
    • pp.365-373
    • /
    • 2022
  • The purpose of this study is to determine the effect of concurrent appointment as a director on the quality of the internal accounting management system (IACS). For analysis, 9,343 KOSPI & KOSDAQ company-year data from 2014-2019, excluding the financial industry, were used. As a result of the analysis, it was confirmed that the quality of IACS decreased as the number of multiple positions in the director increased. Although there is a difference in the roles of inside and outside directors, it was found that the quality of IACS decreases equally as the number of board members. According to the business hypothesis, this can be said to be the result of the agency problem within the company because directors, who were more busy with concurrent positions as directors, did not put sufficient effort into their work. This study suggests that information on the concurrent position of directors can be a new indicator that reflects the characteristics of the board in evaluating the effectiveness of corporate governance.

Study on Relationship between Self-Directed Learning and Career Preparation behavior of College Students: Major Satisfaction, Positive psychological capital, Job-Seeking Stress mediation effect

  • IL Hyun, Yun
    • International Journal of Advanced Culture Technology
    • /
    • v.12 no.2
    • /
    • pp.136-143
    • /
    • 2024
  • The purpose of this study is to analyze the mediating effects of major satisfaction, positive psychological capital, and job-Seeking Stress in the relationship between college students' self-directed learning and career preparation behavior. For this purpose, the study was conducted on 253 college students. The parallel mediation effect was analyzed using SPSS (24.0). Process Macro and Bootstrapping. The following results were confirmed. First, self-directed learning, major satisfaction, positive psychological capital, job-Seeking stress, and career preparation behavior were found to have a mutually significant influence relationship. Second, in the relationship between self-directed learning and career preparation behavior, major satisfaction, positive psychological capital, and job-seeking stress were confirmed to be variables that affect the parallel mediation effect and serial multiple mediation effect.Third, college students' self-directed learning was found to increase career preparation behavior through the mediating roles of major satisfaction, positive psychological capital, and employment stress. Therefore, in order to increase the career outcomes and success rates of college students, their own efforts, professors, and schools must create diverse environments and develop programs for college students' careers. Additionally, follow-up research must continue to supplement this.