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Factors Affecting Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease using Health-Related Quality of Life Instrument with 8 Items (Health-Related Quality of Life Instrument with 8 Items을 사용한 만성폐쇄성폐질환 환자의 건강관련 삶의 질 영향요인)

  • Kim, Seon-Ha;Kim, Miok
    • The Journal of the Korea Contents Association
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    • v.22 no.8
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    • pp.347-357
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    • 2022
  • This study was attempted to identify the health-related quality of life of Chronic Obstructive Pulmonary Disease (COPD) patients and factors influencing the quality of life, focusing on Health-related quality of life with 8 items (HINT-8). The subjects of this study were 451 adults aged 40 years or older who performed lung function tests and whose ratio is less than 0.7 by measuring forced respiratory volume in 1 second [FEV1] to forced vital capacity in the 2019 National Health and Nutrition Examination Survey, It was analyzed using SAS program. As a result, both the HINT-8 index and EuroQol five-dimensions 3-level version (EQ-5D-3L) index were appropriate as tools to measure the health-related quality of life in COPD patients, and the factors affecting the health-related quality of life were age, gender, income, and smoking status, comorbidities, stress, and subjective health status. Therefore, in order to improve the health-related quality of life of COPD patients, an individualized management program suitable for the characteristics of subjects such as the low-income class and the elderly, including smoking cessation education and stress management, should be developed and applied.

Effects of Red-ginseng Extracts on the Activation of Dendritic Cells (고려홍삼의 수지상세포 활성화 효과)

  • Kim, Do-Soon;Park, Jueng-Eun;Seo, Kwon-Il;Ko, Sung-Ryong;Lee, Jong-Won;Do, Jae-Ho;Yee, Sung-Tae
    • Journal of Ginseng Research
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    • v.30 no.3
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    • pp.117-127
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    • 2006
  • Ginseng is a medicinal herb widely used in Asian countries. Dendritic cells(DCs) play a pivotal role in the initiation of T cell-mediated immune responses, making them an attractive cellular adjuvant for use in cancer vaccines. In this study, we examined the effects of Red-ginseng(water extract, edible and fermented ethyl alcohol extract, crude saponin) on the DCs phenotypic and functional maturation. Immature DCs were cultured in the presence of GM-CSF and IL-4, and the generated immature DCs were stimulated by water extract, edible and fermented ethyl alcohol extract, crude saponin and LPS, respectively, for 24hours. The expression of surface co-stimulatory molecules, including MHC(major histocompatibility complex) class II, CD40, CD80 and CD86, was increased on DCs that were stimulated with crude saponin, but antigen-uptake capacity was decreased. The antigen-presenting capacity of Red-ginseng extracts-treated DCs as analyzed by allogeneic T cells proliferation and IL-2, $IFN-{\gamma}$ production was increased. Furthermore, $CD4^+$ and $CD8^+$ syngeneic T cell(OVA-specific) proliferation and $IFN-{\gamma}$ production was significantly increased. However, $CD4^+$ syngeneic T cell secreted higher levels of IL-2 in responding but not $CD8^+$ syngeneic T cell. These results indicate the immunomodulatory properties of Red-ginseng extracts, which might be therapeutically useful in the control of cancers and immunodeficient diseases through the up-regulation of DCs maturation.

Mechanical Properties of a High-temperature Superconductor Bearing Rotor in a 10 kWh Class Superconductor Flywheel Energy Storage System (10 kWh급 초전도 베어링 회전자의 기계적 특성 평가)

  • Park, B.J.;Jung, S.Y.;Kim, C.H.;Han, S.C.;Park, B.C.;Han, S.J.;Doo, S.G.;Han, Y.H.
    • Progress in Superconductivity
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    • v.13 no.1
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    • pp.58-63
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    • 2011
  • Recently, superconductor flywheel energy storage systems (SFESs) have been developed for application to a regenerative power of train, a power quality improvement, the storage of distributed power sources such as solar and wind power, and a load leveling. As the high temperature superconductor (HTS) bearings offer dynamic stability without the use of active control, accurate analysis of the HTS bearing is very important for application to SFESs. Mechanical property of a HTS bearing is the main index for evaluating the capacity of an HTS bearing and is determined by the interaction between the HTS bulks and the permanent magnet (PM) rotor. HTS bearing rotor consists of PM and iron collector and the proper dimension design of them is very important to determine a supporting characteristics. In this study, we have optimized a rotor magnet array, which depends on the limited bulk size and performed various dimension layouts for thickness of the pole pitch and iron collector. HTS bearing rotor was installed into a single axis universal test machine for a stiffness test. A hydraulic pump was used to control the amplitude and frequency of the rotor vibration. As a result, the stiffness result showed a large difference more than 30 % according to the thickness of permanent magnet and iron collector. This is closely related to the bulk stiffness controlled by flux pining area, which is limited by the total bulk dimension. Finally, the optimized HTS bearing rotor was installed into a flywheel system for a dynamic stability test. We discussed the dynamic properties of the superconductor bearing rotor and these results can be used for the optimal design of HTS bearings of the 10kWh SFESs.

Characteristics of Bearing Capacity for SCP Composite Ground reinforced by the Sheet piles Restraining Deformation (변위억제형 Sheet pile 설치에 따른 SCP복합지반의 지지력 특성)

  • Park, Byung-Soo
    • Journal of Navigation and Port Research
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    • v.30 no.8 s.114
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    • pp.711-719
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    • 2006
  • A series of geotechnical centrifuge model tests and numerical modelling have been performed to study engineering characteristics of the composite ground reinforced by both the Sand Compaction Piles(SCPs) and the deformation-reducing sheet piles. The research has covered several key issues such as the load-settlement relation, the stress concentration ratio and the final water content of the ground Totally three centrifuge tests have been conducted by changing configuration of the sheet piles, i.e., a test without the sheet pile, a test with the sheet pile at a single side and a test with the sheet piles at the both sides. In the model tests, a vertical load was applied in-flight on the ground surface. On the other hand, class-C type numerical modelling has been performed by using the SAGE-CRISP to compare the centrifuge test results using an elasto-plastic model for SCPs and the Modified Cam Clay model for the soft clay. It has been found that the sheet piles can restraint failure of foundation, thereby increasing yield stress of the ground. The stress concentration ratio was in the range of $2{\sim}4$. In addition, numerical analysis results showed reductions both in the ground heave($20{\sim}30%$) and in the horizontal movement($28{\sim}43%$), demonstrating the deformation-reducing effect of the sheet piles.

An Extraction of Inefficient Factors and Weight for Improving Efficiency of the Curtain wall Life Cycle Process (커튼월 Life Cycle Process의 효율성 향상을 위한 비효율 요인 밑 중요도 도출)

  • Jung Soon-Oh;Kim Yea-Sang;Yoon Su-Won;Chin Sangyoon
    • Korean Journal of Construction Engineering and Management
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    • v.6 no.4 s.26
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    • pp.101-112
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    • 2005
  • Recently, a curtain wall construction is a exterior finishing components which is most used for shortening time in high-rise building as well as the class of key management factors in cost and schedule control. Also, it is recognized that an effective management for curtain wall process is a major subject to accomplish the project successfully. However, as the current management for curtain wall construction is focused on the construction stage, it makes problems such as errors in business performance, rework by mistakes and duplications, errors and omissions by ineffective information management and there has never been any efficient management from a view of the entire Curtain Wall Life-cycle process. Therefore, the aim of this study is to suggest a stage check point for process improvement in the curtain wall Life-cycle process through current curtain wall process analysis, and then to investigate the cause of waste factors using the Muda method from the Toyota Production System and extract the weighted effects of the waste factors using the analytical hierarchy process method. According to the result, Most of the inefficient factors happened in architectural design stage of the entire curtain wall Life-cycle process and my research identified that detail factors of them are a delay of decision making and an approval in changes, a deficit of engineering capacity and a delay of approval in architectural design drawings by owner, etc.

Etiologic and Immunologic Characteristics of Thoroughbred Horses with Bacterial Infectious Upper Respiratory Disease at the Seoul Race Park

  • Ryu, Seung-Ho;Koo, Hye-Cheong;Park, Young-Kyung;Kim, Jun-Man;Jung, Woo-Kyung;Davis, William C.;Park, Yong-Ho;Lee, Chang-Woo
    • Journal of Microbiology and Biotechnology
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    • v.19 no.9
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    • pp.1041-1050
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    • 2009
  • Equine respiratory disease is a common cause of poor performance and training interruptions. The higher incidence rate of infectious upper respiratory disease (IURD) in thoroughbred racehorses at the Seoul Race Park coincided with the frequent stabling season, shorter stabling periods, and younger ages in this study. Incidence rates were also correlated with significantly lower proportions of cells expressing MHC class II-, CD2 antigen-, $CD4^+$- or $CD8^+$-T lymphocyte-, and B lymphocyte in IURD patients compared with healthy control groups in the summer and fall and in 2-and-3-year-old groups. The data suggested that movement and new environments may have resulted in immunosuppression and inappropriate responses to respiratory pathogens in IURD patients. The IURD incidence decreased with age, perhaps by the acquisition of immunity, and study results suggested that immunologic protection was associated with IURD, particularly in young thoroughbred racehorses. Streptococci isolates were identified in 11 of 72 IURD horses, and 3 of these isolates were identified as Streptococcus. equi subsp. equi. S. equi subsp. zooepidemicus was isolated from 2 of 23 IURD horses in the spring (8.7%), 5 of 23 in the summer (21.7%), and 1 of 6 in winter (16.7%). S. equi subsp. zooepidemicus (5%) was also identified in 3 of 61 isolates from clinically normal horses. Racetracks should implement anti-IURD protective measures by assessing the capacity of equine immunologic protection at the Park and by limiting the introduction of specific respiratory pathogens (such as S. equi subsp. equi) by preventing the access of infected but subclinical horses with a specified respiratory pathogen-free certification system prior to Park entry.

Charge-discharge Characteristics of $LiCoO_2/Li$ Rechargeable Cell ($LiCoO_2/Li$ 2차전지의 충방전 특성)

  • Moon, S.I.;Doh, C.H.;Jeong, E.D.;Kim, B.S.;Park, D.W.;Yun, M.S.;Yeom, D.H.;Jeong, M.Y.;Park, C.J.;Yun, S.K.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1993.05a
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    • pp.79-84
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    • 1993
  • This paper describes the development of lithium rechargeable cell. $LiCoO_2$ is recently recognized as a suitable cathode active material of a high voltage, high energy lithium rechargeable batteries because $Li^+$ ion can be electrochemically deintercalated/intercalated from/to $Li_xCoO_2$. The transition metal oxide of $LiCoO_2$ was investigated for using as a cathode active material of 4V class Li rechargeable cell. $LiCoO_2$ cathode was prepared by using a active material of 85 wt%, graphite powder of 12 wt% as a conductor and poly-vinylidene fluoride of 3 wt% as a binder. The electrochemical and charge/discharge properties of $LiCoO_2$ were investigated by cyclic voltammetry and galvanostatic charge/discharge. The open circuit voltage of prepared $LiCoO_2$ electrode exhibited approximately. potential range between 3.32V and 3.42V. During the galvanostatic charge/discharge, $LiCoO_2/Li$ cell showed stable cycling behavior at scan rate of 1mV/sec and potential range between 3.6V and 4.2V. Also its coulombic efficiency as function of cycling was 81%~102%. In this study the $LiCoO_2/Li$ cell showed the available discharge capacity of 90.1 mAh/g at current density of $1mA/cm^2$ and cell discharge voltage range between 3.6V~4.2V.

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A study on AI Education in Graduate School through IPA (대학원 인공지능교육의 방향 탐색: IPA를 활용하여)

  • Yoo, Jungah
    • Journal of The Korean Association of Information Education
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    • v.23 no.6
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    • pp.675-687
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    • 2019
  • As interest in artificial intelligence increases, each university has been establishing a special graduate school with artificial intelligence major, and recently, the Korea government has established various support policies for artificial intelligence education. However, each university has a lot of difficulties because it has little experience in operating graduate education with the latest field of artificial intelligence and it is not easy to find experts. In this study, the response of graduate school students majoring in artificial intelligence was analyzed using IPA technique, and the direction of education of graduate school artificial intelligence major was searched. Among the 40 items surveyed by IPA, 12 items such as systematization of artificial intelligence curriculum, progress of class considering learning level, improvement of academic relations with guidance professors were extracted as items to be improved first. On the other hand, 8 items such as assistant capacity, and relationship with colleagues were overloaded, and twelve items such as instructor's lecture competency, appropriateness of educational contents, learner's artificial intelligence skills and knowledge, and attitude acquisition were to be maintained. In addition, eight items such as convergence education curriculum and diversity of education methods were all low in importance and performance. It is suggested that AI graduate school should be divided into two tracks(technical specialization, convergence expansion) by educational goal, and each track should be conducted by level-specific educational contents and methods suitable for student level. The curriculum should be elaborate and systematic to acquire AI knowledge, skills, and attitudes, and should have an individualized guidance system centered on excellent faculty members.

A Study on the Establishment and Application of Evaluation Criteria for Old Railway Station Considering the Level of Railway Service (철도 서비스수준을 고려한 노후철도역사 평가기준 마련 및 적용방안)

  • Kim, Kyung Ho;Kim, Si Gon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.44 no.1
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    • pp.101-108
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    • 2024
  • The total number of railroad stations managed in Korea is 322 (including general and wide-area railways), and a considerable number of stations are aging. In terms of the size of the existing railway station and the number of entrances, it has not been possible to secure adequate service capacity, and the demand for station improvement is increasing due to changes in surrounding conditions such as urban development. In the past, railroad stations were focused on the simple function of a connection passage in terms of maintenance or management, but in recent years, railroad stations are also changing to an atmosphere that they should be reborn as a user-centered comfortable, convenient, and safe service provision space. In this study, a case study related to the improvement of the old railway station was conducted to derive an improvement plan that meets the improvement standard of the old station, and the service level evaluation standard was developed. By introducing the concept of service level (LOS) in the development model, station congestion, station movement convenience, and station safety were selected as evaluation indicators. In addition, this development model applied an analytical stratification technique to divide various evaluation elements of each indicator into major and detailed elements and derive the relative importance of the elements by class. Priority for improvement was derived using the ratio of the number of E and F on the LOS for each facility. Based on this study, it is expected to be helpful in using it as an evaluation criterion for improving objective and equitable railway station.

Relationship between Oxygen Uptake and Cardiac Output on Maximal Treadmill Exercise in Marathoners by Improved Impedance Cardiography (Treadmill 최대 운동시 Impedance 심장기록법의 개선에 의한 마라톤 선수의 심박출량과 산소소비량과의 관계)

  • Kang, Doo-Hee;Hwang, Soo-Kwan;Yeon, Dong-Soo;Yuh, Seon-Hee;Kim, Deok-Won
    • The Korean Journal of Physiology
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    • v.24 no.2
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    • pp.249-260
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    • 1990
  • Maximal cardiac output and oxygen uptake $(VO_{2max})$ were measured during treadmill exercise for seven top-class marathoners and nine non-athletes using impedance cardiograph developed by one of the authors (DW Kim). Results of this study are summarized as belows. 1) New shoes with sponge and silicon rubber attached to the soles were developed to reduce motion artifact during treadmill exercise. Ensemble everaging techneque with the developed shoes was also used to improve the measurement of stroke volume using impedance cardiography. 2) Maximal cardiac output of the athletes, 14.98 L/min, was significantly higher than that of the non-athletes, 13.46 L/min. As maximal heart rate of the marathoners is lower than that of non-athletes, stroke volume of the former is significantly larger than that of the latter. 3) $VO_{2max}$ of the marathoners, 59.38 ml/kg/min, was higher than that of the non-athletes, 40.22 ml/kg/min. At the anaerobic threshold. $VO_{2max}$ of the former was 62.3% of $VO_{2max}$ and this was significantly higher than that of the non-athletes, 57.2%, This results indicates that the marathoners have higher aerobic capacity than the non-athletes. 4) The marathoners showed larger $VO_2$ than the non-athletes at the same cardiac output, indicating that a-v $O_2$ of the former is higher than that of the latter. 5) Maximal systolic pressure of the marathoners was higher than that of the non-athletes, and so was maximal rate-pressure products. These results indicate that heart oxygen consumption rate $(hVO_2)$ of the marathoner is higher than that of the non-athletes is mainly due to higher stroke volume. And higher oxygen consumption of the marathoners is due to higher stroke volume. And higher oxygen consumption of the marathoners is due to their larger a-v $O_2$. The marathoners show both higher threshold and $VO_{2max}$. Especially, measurement of cardiac output during treadmill exercise by improved impedance cardiography is expected to contribute in study of cardiac function of athletes.

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