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Association of total dietary antioxidant capacity with oxidative stress and metabolic markers among patients with metabolic syndrome (대사증후군 환자 및 위험군의 식사 내 총 항산화능과 산화스트레스 및 대사 지표의 연관성)

  • Ham, Dongwoo;Jun, Shinyoung;Kang, Minji;Shin, Sangah;Wie, Gyung-Ah;Baik, Hyun Wook;Joung, Hyojee
    • Journal of Nutrition and Health
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    • v.50 no.3
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    • pp.246-256
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    • 2017
  • Purpose: This study aimed to investigate the association of total dietary antioxidant capacity (TAC) with oxidative stress and metabolic markers among patients with metabolic syndrome according to gender. Methods: A total of 346 subjects aged 30~59 years with two or more risk factors of metabolic syndrome were recruited from a general hospital near Seoul in South Korea between 2010 and 2012 based on data from the medical checkup. Biochemical indices for oxidative stress and metabolic markers were measured. Food consumption data from 3-day food records were linked with the antioxidant capacity database for commonly consumed Korean foods to estimate individual's TAC. Results: Average dietary TAC of the study subjects was 132.0 mg VCE/d/1,000 kcal in men and 196.4 mg VCE/d/1,000 kcal in women. Levels of ${\gamma}$-glutamyltransferase (GGT), systolic blood pressure, diastolic blood pressure, and blood triglycerides were reduced significantly according to increasing TAC in men, but there was no significant trend in women. Intakes of total flavonoids and carotenoids were significantly negatively correlated with GGT (p < 0.05) and d-ROMs (p < 0.01) in men, whereas those of ${\alpha}$-tocopherol (p < 0.05) and ${\gamma}$-tocopherol (p < 0.05) were positively correlated with biological antioxidant potential (BAP) in women. The odds ratio of high oxidative stress indices and abnormal metabolic markers according to TAC level were not significant in either men or women. Conclusion: The results show that dietary TAC was partially associated with oxidative stress and metabolic markers among patients with metabolic syndrome. Further research is required for elucidating the association between dietary TAC and incidence of metabolic syndrome and chronic diseases within a large population in prospective studies.

Differential Association of History of Premenstrual Syndrome/Premenstrual Dysphoric Disorder with Vasomotor Symptoms According to Menopausal Stage (폐경 단계에 따른 월경전 증후군/월경전 불쾌장애의 과거력과 혈관운동증상의 차별적 연관성)

  • Hyun, Hong-Dae;Joe, Sook-Haeng;Jeong, Hyun-Ghang;Ko, Young-Hoon;Kwon, Eunjoo;Kim, Hyekyeong;Ko, Seung-Duk
    • Korean Journal of Psychosomatic Medicine
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    • v.23 no.1
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    • pp.57-65
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    • 2015
  • Objectives:Within the normal reproductive cycles of women, dramatic fluctuations of sexual hormones occur in the premenstrual and menopausal periods. In both periods, women are vulnerable to mood disturbances and show several somatic complaints. Based on these common clinical profiles and physiological changes, a relationship between vasomotor symptoms and the premenstrual syndrome has been suggested. However, attempts to establish such a link have yielded inconclusive results. The purpose of this study was to investigate the association between histories of premenstrual syndrome and menopausal vasomotor symptoms within different menopausal stages. Methods:This cross-sectional study recruited Korean women aged 45-64 years who were perimenopausal and postmenopausal from 16 branch offices of the Korean Association of Health Promotion. All subjects completed self-report questionnaires that asked about a history of premenstrual syndromes, vasomotor symptoms, and several other variables. Results:A total of 1054 participants(361 perimenopausal women and 693 postmenopausal women) completed the study. Severity of premenstrual symptoms significantly correlated with postmenopausal vasomotor symptoms, only in late perimenopausal(r=0.213, p=0.010) and early postmenopausal women(r=0.246, p<0.001). After adjusting for several factors related to vasomotor symptoms, a history of premenstrual syndrome was a significant predictor of moderate to very severe vasomotor symptoms in late perimenopausal(OR=5.197, p=0.005) and early postmenopausal women(OR=3.017, p=0.010). Conclusions:This study suggests that a history of premenstrual syndrome/premenstrual dysphoric disorder is differentially associated with vasomotor symptoms in the menopausal stage. Prospective studies with larger population are needed to confirm these findings

Results of radiofrequency catheter ablation in children and adolescent with tachyarrhythmia (소아 청소년 부정맥 환자에서 고주파 전극도자 절제술의 이용 성적)

  • Chang, Young Beom;Lee, Seung Hyun;Kang, Eun Young;Rhee, Kyoung-Suk;Joo, Chan Uhng
    • Clinical and Experimental Pediatrics
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    • v.50 no.11
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    • pp.1085-1090
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    • 2007
  • Purpose : Radiofrequency catheter ablation (RFCA) has become an effective therapeutic modality for treating pediatric tachyarrhythmias. Using conventional RFCA catheters, ablation of parahisian accessory pathways may be difficult and have high risk for heart block. We reviewed the efficacy and complications of the RFCA in children and adolescent with arrhythmias including parahisian accessory pathways. Methods : We studied 48 patients (aged 2 years to 20 years) who had undergone RFCA from August 2003 to March 2007. We reviewed clinical findings, electrophysiologic studies, RFCA data, complications, and follow-up results of the patients. Results : Mean age of the patients was 13.1 years. Numbers and types of arrhythmias (age, acute success rate) were as follows: 19 WPW syndrome including 5 parahisian accessory pathways ($13.7{\pm}4.6yr$, 18/19), 11 atrioventricular reentrant tachycardia with concealed bypass tract ($12.3{\pm}5.0yr$, 10/11), 13 atrioventricular nodal reentrant tachycardia ($12.6{\pm}4.4yr$, 13/13), 4 atrial flutter ($13.0{\pm}7.4yr$, 3/4), and 1 ventricular tachycardia (20 yr, 1/1). Associated cardiac structural lesion was not detected in 48 patients. The recurrence rate was 6.5%, and the final success rate was 93.8%. Conclusion : These results suggest that RFCA is a highly effective treatment method in children and adolescent with tachyarrhythmia.

Effects of Supplementation of Trace Nutrients on Hanwoo Heifers (Bos taurus coreanae) under Hilly Pasture Grazing System (산지 방목기간 중 미량영양소 급여가 한우 암소의 생산성에 미치는 영향)

  • Yang, Seung Hak;Yang, Byoung Chul;Chung, Ki Yong;Jang, Sun Sik;Lee, Eun Mee;Cho, Sang Rae;Lee, Suk Dong;Park, Hyung Soo;Kwon, Eung Gi
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.4
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    • pp.387-392
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    • 2016
  • This study was conducted to ameliorate the productive performance of Hanwoo cow using hill pasture grazing system. Twenty seven animals aged 9 were designed to divide with 3 groups which were Control (restricted concentrate and hay for 5 months), T1 (restricted concentrate and pasture grazing ad libitum for 5 months) and T2 (restricted concentrate, 30 g/head of mineral nutrients and pasture grazing ad libitum for 5 months). Average daily gains increased higher in the order of T2, Control and T1. The conception rate of Control, T1 and T2 after artificial insemination during post-grazing period were 88.9%, 100%, 100%, respectively. In conclusion, the results indicated that hill pasture grazing system might enhance not only the productive performance of Hanwoo cow but also profit for conventional feeding system.

A Study on Nutritional Status of the Long-lived Elderly People in Kyungnam (경남 일부지역 장수노인의 영양섭취상태에 관한 연구)

  • 최희정;김경업;김성희;강동희;정효숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.5
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    • pp.877-884
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    • 2002
  • This study was carried out to examine nutrients intake and food preference in 100 elderly people aged over 85 years residing in Namhae-gun Kyungnam. Mean daily energy intake and Korean recommended dietary allowances (RDA) percent were 1547.6$\pm$452.7 kcal and 91.5%, respectively. Mean daily intakes of protein (63.1$\pm$28.2 g), iron (16.7$\pm$11.2 mg), vitamin Bi (1.0410.4 mg) and vitamin C (97.0$\pm$45.3 mg) were higher than RDA. The intakes of calcium (418.1$\pm$189.7 mg) and vitamin B2 (0.94$\pm$0.5 mg) were shown to be 58.4% and 78.4% of the RDA. Females had higher intakes of energy and most other nutrients than males. Major food source of energy and protein intakes was rice and cereals, and that of lipid intake was meat, fish, egg and beans. Cooked rice, all kind of vegetables, fish, yogurt and sugars were preferred to the subjects. The most preferred taste was sweet.

Changes of Physicochemical Properties during Fermentation of Peach Wine and Quality Improvement by Ultrafiltration (복숭아주 발효시 이화학적 특성변화와 한외여과에 의한 품질 향상)

  • 정재호;목철균;임상빈;박영서
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.4
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    • pp.506-512
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    • 2003
  • Peach wine was fermented at $25^{\circ}C$ for 2 weeks using Saccharomyces cerevisiae KCCM 12224, aged at 15$^{\circ}C$ for 14 weeks, and its physicochemical and microbiological changes were investigated. The viable bacterial cell numbers, 1.4$\times$10$^3$ CFU/mL at the beginning of fermentation, increased to 2.8$\times$10$^{6}$ CFU/mL after 2 weeks, but decreased to 7.0$\times$10$^3$ CFU/mL after 14 weeks. The viable yeast cell numbers were changed from 3.4$\times$10$^2$ CFU/mL to 2.4$\times$10$^{7}$ CFU/mL during fermentation, and decreased to 4.0$\times$10$^4$ CFU/mL after aging. Turbidity total sugar content, reducing sugar content, solid content and b value of peach wine decreased during fermentation but acidity, alcohol content, L and a value increased. Most physicochemical properties except alcohol content and reducing sugar content were not changed significantly during aging. When peach wine was filtered through 0.45 ${\mu}{\textrm}{m}$ nitrocellulose membrane followed by various ultrafiltration membranes with different molecular weight cut-off values, Biomax 100K membrane, with 79 liter/$m^2$/h (LMH) of initial flux, was suitable for ultrafiltration process of peach wine. These membrane filtration treatments resulted in complete removal of microorganisms and decrease in turbidity and alcohol content without changes in other chemical properties. The physicochemical properties of peach wine were not changed and any microorganisms were not found during the storage at 3$0^{\circ}C$ for 12 Weeks.

Serum 25-hydroxyvitamin D levels are associated with dental caries experience in Korean adolescents: the 2010~ 2014 Korean National Health and Nutrition Examination Surveys (청소년에서 혈중 비타민 D 농도와 치아우식 경험 간의 연관성 : 2010~ 2014 국민 건강영양조사)

  • Choi, Soyeon;Seo, Deog-Gyu;Hwang, Ji-Yun
    • Journal of Nutrition and Health
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    • v.51 no.4
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    • pp.287-294
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    • 2018
  • Purpose: This study was conducted to evaluate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and dental caries experience in Korean adolescents based on the 2010 ~ 2014 Korean National Health and Nutrition Examination Surveys. Methods: The study subjects were 2,655 Korean adolescents aged 10 to 18 years. Subjects were classified into four groups according to their serum 25(OH)D levels. We used logistic regression to evaluate the relationship between vitamin D and for dental caries experience after adjusting for age, household income level, recipient of basic livelihood, tooth brushing and visiting dental clinics. Result: Multiple logistic regression analysis showed that serum 25(OH)D insufficiency (20 ng/mL ${\leq}25(OH)D$ < 30 ng/mL) was associated with increased odd ratios (ORs) for dental caries experience in boys (OR = 2.577, 95% CI = 1.013-6.557), compared with serum 25(OH)D sufficiency (25(OH)D ${\geq}30ng/mL$). Conclusion: The serum 25(OH)D levels were found to be related to risk of dental caries experience in Korean adolescent boys.

A study of the frequency and characteristics of minor clinical manifestations in children with atopic dermatitis (소아 아토피피부염 환자의 부증상 빈도 및 특징에 대한 연구)

  • Cho, Ji Eun;Jeon, You Hoon;Yang, Hyeon Jong;Pyun, Bok Yang
    • Clinical and Experimental Pediatrics
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    • v.52 no.7
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    • pp.818-823
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    • 2009
  • Purpose : We aimed to evaluate the frequency and characteristics of minor clinical manifestations of atopic dermatitis (AD) in Korean children to aid the diagnosis and treatment of AD. Methods : From April 2007 to December 2007, we enrolled 106 children (aged 1 month [infants] to 15 years) diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital. Clinical manifestations were examined and laboratory findings (total and specific immunoglobulin E [IgE] levels and peripheral blood eosinophil count) were analyzed and compared. Results : Minor symptoms, in order of frequency, included xerosis (78.3%), aggravation due to environmental or emotional stress (43.4%), lichenification (35.8%), orbital darkening (34.0%), periauricular eczema (33.0%), and cutaneous infection (31.1%). Older children (${\geq}2$ years) showed more orbital darkening (P=0.01), horizontal crease (P=0.01), and lichenification (P=0.001) than infants. Patients with severe AD (scoring atopic dermatitis [SCORAD] score, ${\geq}40$) showed higher frequencies of xerosis (P= 0.04), cutaneous infection (P=0.03), ichthyosis (P=0.18), keratosis pilaris (P=0.02), pityriasis alba (P=0.07), recurrent conjunctivitis (P=0.02), orbital darkening (P=0.001), aggravation due to environmental or emotional stress (P=0.05), facial eczema (P=0.001), lichenification (P=0.001), and hand/foot eczema (P=0.04) than those with mild-to-moderate AD. Children with atopic eczema showed more facial eczema (P=0.01) and lichenification (P=0.04) than those with non-atopic eczema. Conclusion : The clinical manifestations of AD were similar to those established by Hanifin and Rajka. However, we need to develop our own diagnostic criteria for AD, because the frequencies shown by our subjects differed from those observed in other countries.

Risk Factors Affecting Severity of Menopausal Symptoms in Early and Late Postmenopasusal Woman (초기와 후기 폐경후기 여성에서의 폐경기 증상의 심각도와 위험 요인들)

  • Kim, Jong-Hun;Lee, Moon-Soo;Yang, Jae-Won;Ko, Young-Hoon;Ko, Seung-Duk;Joe, Sook-Haeng
    • Korean Journal of Psychosomatic Medicine
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    • v.17 no.2
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    • pp.52-61
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    • 2009
  • Objectives : The aim of this study was to assess health-related quality of life and evaluate the risk factors affecting severity of menopausal symptoms in early and late postmenopausal women based on the stages of reproductive aging workshop(STRAW) paradigm. Methods : This cross-sectional study examined 497 Korean postmenopausal women aged 41-59 years in Seoul and Gyeonggi province. We divided subjects into early postmenopause group and late postmenopause group. Menopause Rating Scale(MRS) was used to measure the quality of life. MRS scores, sociodemographic variables, smoking, alcohol use, age at menopause, and risk factors such as attitude to menopause, depression, history of premenstrual dysphoric disorder were compared between early and late postmenopause groups. Multiple regression analysis was performed in each group to assess the independent contribution of several variables. Results : Early postmenopause group showed significantly higher MRS scores, more negative attitude toward menopause, higher scores of depressive symptoms than late postmenopause group. Moderate to very severe hot flush group showed significantly, more negative attitude toward menopause, higher score of depressive symptoms, and higher MRS scores than none to mild hot flush groups. Depressive symptoms and attitude toward menopause contributed to the severity of menopausal symptom in both early and late postmenopause groups. Chronological age, age at menopause, history of PMDD contributed to severity of menopausal symptoms in early postmenopause group while marital status and occupation contributed in late postmenopause group. Conclusion : Health-related quality of life in postmenopause women was significantly lower in early postmenopause group than the late. Attitude toward menopause and depressive symptoms contributed significantly to quality of life in both early and late postmenopause groups but other variables contributed differently in each group. Further studies on clinical samples of postmenopausal women in order to confirm quality of life and its risk factor are needed to be done.

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Visual fatigue in Watching 3 Dimension Television (3D TV 시청에 있어서 시청 피로)

  • Yoon, Jeong Ho;Lee, Ikhan;Kim, Taehyun;Kim, Jae-Do
    • Journal of Korean Ophthalmic Optics Society
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    • v.17 no.1
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    • pp.47-52
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    • 2012
  • Purpose: This study was to evaluate visual fatigue with passing of watching 3D TV in short term and with experience of watching 3DTV in long term. Methods: 98 adult subjects aged $33.5{\pm}5.5$ years (22 to 51 years; 12 females and 86 males) agreed to participate in this study. Subjects were asked to watch 52 inch LED 2D and 3D television (Shutter glasses method) at 2.7 meters for 65minutes with wearing their habitual glasses or contact lenses. For evaluating visual fatigue, subjects were verbally responded to 11 questions : eye straining, eye paining, dry eye, sore eye, watery eye, photophobia, blur vision, diplopia, eye fatigue, headache, and dizziness with scale 0 to 3 at each measurement while watching 3D and 2D TV. Results: The mean scores of visual fatigue were $2.08{\pm}2.14$, $3.19{\pm}3.02$, $3.40{\pm}3.37$, $3.53{\pm}3.07 $for after 5 minutes, 25 minutes, 45 minutes, and 65 minutes respectively for 3D TV, and $0.40{\pm}1.03$, $0.22{\pm}0.70$, $0.22{\pm}0.58$, and $0.17{\pm}0.52$ after 25, 45, and 65 minutes respectively for 2D TV. Visual fatigue for watching 3D TV was significantly higher than for watching 2D TV at all measurements sessions (paired t-test, p < 0.001). The visual fatigue significantly increased during watching 3D TV for 65 minutes (p < 0.001, RM-ANOVA). The visual fatigue during watching 3D TV was significantly increased until 25 minutes (paired t-test, p < 0.001), stable after that. For correlation between visual fatigue and 3D watching experience, the more 3D watching experiences were significantly the less visual fatigues in photophobia, blur vision, diplopic and dizzy symptoms (ANOVA, all F(1, 96) = 4.500, all p < 0.05), but there was not significantly different in the other symptoms (ANOVA, F (1, 96) = 2.123, p = 0.148). Conclusions: Visual fatigue for watching 3D TV was higher than for watching 2D TV, increase by 25 minutes. It was different by symptoms for correlation between visual fatigue and 3D watching experience.