• Title/Summary/Keyword: the Independent Investigation Method

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γ-aminobutyric Acid Content in House Rat and Fowl Brain (집쥐와 닭 뇌의 γ-Aminobutyric acid 함량)

  • Huh, Rhin Sou
    • Korean Journal of Veterinary Research
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    • v.11 no.1
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    • pp.59-63
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    • 1971
  • Current interest in ${\gamma}$-aminobutyric acid (GABA) has arisen from the convergence of several independent line of investigation leading to the demonstration that this and related substances are normal products of brain metabolism and that GABA has an important physiological action upon brain function as well as upon certain peripheral nervous structures. The interest for neurophysiologists has been enhanced by the importance of the discovery for the role of humoral mediator of synaptic transmission or regulator of neuronal activity in the central nervous system, particularly if it may shed some elight upon the nature of central inhibitory processes. In accordance with such an interest and importance, this work was performed in order to standardize the normal content as a preliminary investigation of so-called night active and daytime active animals GABA content in their brains when they are exposed to light and darkness. The method, through which the estimation has made in this work, was paper chromatographic method developed by Maynert and Klingman for the estimation of GABA content in animal tissues. The results obtained are summerized as follows: 1) GABA content in the cerebral cortex of house rat ranged from 90 to $310{\mu}g/gm$ of wet weight. 2) The content of GAGA ranging from 130 to $510{\mu}g/gm$ of wet weight was occurred from midbrain of the rat. 3) GABA content was ranged from 30 to $150 {\mu}g/gm$ of wet weight of the rat cerebellum. 4) The contents of fowl cerebral cortex, midbrain, and cerebellum are estimated as ranging 230-590, 250-620, $50-280{\mu}g/gm$ of wet weight, respectively. As a result, it may be concluded that among three brain tissues of both animals the midbrain is the highest region in GABA content. Fowl brain, on the other side, contains more higher GABA content than the house rat brain does.

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Analysis of the Operation Status and Function based on the Overseas Accident Investigation Agency (국외 재난원인조사기구의 운영 현황 및 기능분석)

  • Lee, Kyung-Su;Yang, Seung-Ho;Kim, Yeon-Ju;Park, Jihye;Kim, Tai-Hoon;Kim, Hyunju
    • Journal of the Society of Disaster Information
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    • v.17 no.3
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    • pp.442-453
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    • 2021
  • Purpose: The objective of this study is to suggest desirable direction of Korean accident investigation organization by analyzing the operation status and way of overseas developed countries' investigation agency. Method: To accomplish the objective of this study, we were examined four main characteristics of accident investigation agencies of the U.S., Japan, and Sweden, focusing on (1); the background of the establishment, (2);organizational structure, (3);major tasks and functions, (4); accident investigation procedures. Result: First, the purpose of its establishment and task is to prevent recurrence of disasters and accidents, at the same time, administrating and researching duties such as legal system, policy, recommending improvement and conducting scientific disaster-cause analysis to contribute safety for the government. Second, it is operated as an independent organization under the president, not belonging to the ministry, in order to enable fair investigation in an impartial position. Third, it has the authority to be recognized for its expertise in the results of investigation. In other words, it is operated as a permanent organization with professional personnel, and secures authority through the accident research with indepth investigation and high-quality recommendations. Conclusion: The overseas investigation agencies rapidly manage and coordinate their operational practices in order to resolve national requirements and social conflicts with fairness, accuracy and expertise in accident investigations. In order to prevent the recurrence of similar events, Korea needs to efficiently reconstruct its investigative functions distributed by each government department. In addition, institutional improvement is needed to make general adjustments at the national level, organize and operate control tower for when the accident has happened.

Investigation on the Factors Determining the Size Distribution of Gold Nanoparticles in the Citrate Reduction Method

  • Kang, Ae-Yeon;Park, Dae-Keun;Lee, Cho-Yeon;Yun, Wan-Soo
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.554-554
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    • 2012
  • Controlling the size distribution of gold nanoparticles (NPs) is of great importance due to the fact that their properties are strongly dependent upon the size distribution as well as the size itself. In the citrate reduction method for gold NP synthesis, the citrate works as (1) a reducing agent, (2) a surfactant, and also (3) a weak base: it raises the pH of the whole reaction mixture. Here, we have extensively studied the all three roles of the citrate, by adding other reagents separately (NaBH4, CTAB, and NaOH) for the independent control of the three roles of the citrate. Among the roles of the citrate, that as a weak base was found to be the most critical parameter affecting the size distribution of gold NPs and the size distribution became much more improved with the increase of the solution pH, while adding a supplementary surfactant or reducing agent resulted in the formation of less homogeneous NPs.

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Numerical investigation of SHS steel beam-columns strengthened using CFRP composite

  • Keykha, Amir Hamzeh
    • Steel and Composite Structures
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    • v.25 no.5
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    • pp.593-601
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    • 2017
  • Carbon Fiber Reinforced Polymer (CFRP) is one of the materials used to strengthen steel structures. Most studies on strengthening steel structures have been done on steel beams and steel columns. No independent study, to the researcher's knowledge, has studied the effect of CFRP strengthening on steel beam-columns, and it seems that there is a lack of understanding on behavior of CFRP strengthening on steel beam-columns. However, this study explored the use of adhesively bonded CFRP flexible sheets on retrofitting square hollow section (SHS) steel beam-columns, using numerical investigations. Finite Element Method (FEM) was employed for modeling. To determine the ultimate load of SHS steel beam-columns, ten specimens, eight of which were strengthened with the different coverage length and with one and two CFRP layers, with two types of section (Type A and B) were analyzed. ANSYS was used to analyze the SHS steel beam-columns. The results showed that the CFRP composite had no similar effect on the slender and stocky SHS steel beam-columns. The results also showed that the coverage length, the number of layers, and the location of CFRP composites were effective in increasing the ultimate load of the SHS steel beam-columns.

An Analysis on the Research Method of Elderly Residents' Opinion towards the Physical Environments of the Facilities for the Elderly : Focusing on Foreign Academic Journal Articles since 1990 (노인시설의 물리적 환경에 대한 거주노인 의견 조사방법의 분석 : 1990년 이후 해외 학술논문자료를 중심으로)

  • Lee, Min-Ah
    • Journal of Families and Better Life
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    • v.33 no.2
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    • pp.35-51
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    • 2015
  • The purpose of this study was to provide information for research about residents' opinion toward the physical environments of elderly facilities, through the analysis and investigation on the research methodology of foreign academic journal articles from 1990 to 2014. The study results were as follows: Firstly, purposive sampling was a large majority of both facilities and elderly residents. In quantitative studies, many researchers have conducted simple random, cluster, or stratified sampling. Diverse facilities in area, size, location, and etc. should be considered for participation. The qualifications for residents' participation should be considered as well, so that they all could have autonomy for study participation. Secondly, questionnaire and semi-structured guide were likely to be used in independent and resident care facilities. On the other hand in assisted living and long-term care facilities, open questions and visual material were used as well. A compatible scale should be developed so that elderly having variable functional level could participate independently in the study. Thirdly, in data collection process, compliance with research ethics and well trained interviewer's skill were important for residents' active responses and minimization of response errors. Enough research period of time and mixed study in data collection will decrease the response error.

Systematic Approach for Predicting Irregular Wave Transformation (불규칙파랑의 계통적 취급수법)

  • 권정곤
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.2 no.2
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    • pp.83-95
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    • 1990
  • It can be assumed that the ocean waves consist of many independent pure sinusoidal components which progress in arbitrary directions. To analyze irregular sea waves, both the spectrum method and the individual wave method have been used. The spectral approach is valid in the region where the water depth is deep and the linear property of velocity distribution is predominent, while the individual wave analysis method in the region where the water depth is shallow and the wave nonlinearity is significant. Therefore, to investigate the irregular wave transformation from the deep water to the shallow water region, it is necessary to relate the frequency spectrum which is estimated by the spectrum analysis method to the i oint probability distribution of wave height, period and direction affected by the boundary condition of the individual wave analysis method. It also becomes important to define the region where both methods can be applied. This study is a part of investigation to establish a systematic approach for analyzing the irregular wave transformation. The region where the spectral approach can be applied is discussed by earring out the experiments on the irregular wave transformation in the two-dimensional wave tank together with the numerical simulation. The applicability of the individual wave analysis method for predicting irregular wave transformation including wave shoaling and breaking and the relation between frequency spectrum and joint probability distribution of wave height and period are also investigated through the laboratory experiment and numerical simualtion.

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Resolving a velocity inversion at the geotechnical scale using the microtremor (passive seismic) survey method

  • Roberts James C.;Asten Michael W.
    • Geophysics and Geophysical Exploration
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    • v.7 no.1
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    • pp.14-18
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    • 2004
  • High levels of ambient noise and safety factors often limit the use of 'active-source' seismic methods for geotechnical investigations in urban environments. As an alternative, shear-wave velocity-depth profiles can be obtained by treating the background microtremor wave field as a stochastic process, rather than adopting the traditional approach of calculating velocity based on ray path geometry from a known source. A recent field test in Melbourne demonstrates the ability of the microtremor method, using only Rayleigh waves, to resolve a velocity inversion resulting from the presence of a hard, 12 m thick basalt flow overlying 25 m of softer alluvial sediments and weathered mudstone. Normally the presence of the weaker underlying sediments would lead to an ambiguous or incorrect interpretation with conventional seismic refraction methods. However, this layer of sediments is resolved by the microtremor method, and its inclusion is required in one-dimensional layered-earth modelling in order to reproduce the Rayleigh-wave coherency spectra computed from observed seismic noise records. Nearby borehole data provided both a guide for interpretation and a confirmation of the usefulness of the passive Rayleigh-wave microtremor method. Sensitivity analyses of resolvable modelling parameters demonstrate that estimates of shear velocities and layer thicknesses are accurate to within approximately $10\%\;to\;20\%$ using the spatial autocorrelation (SPAC) technique. Improved accuracy can be obtained by constraining shear velocities and/or layer thicknesses using independent site knowledge. Although there exists potential for ambiguity due to velocity-thickness equivalence, the microtremor method has significant potential as a site investigation tool in situations where the use of traditional seismic methods is limited.

An Investigation into the Nurturing Strategy of Korean Young Designers in the International Market Expansion - Based on London's Young Designers' Support Programs - (국내 신진패션디자이너의 해외시장 진출 전략 연구 - 영국 런던시의 지원 사업을 기초로 -)

  • Kim, Hye Eun
    • Fashion & Textile Research Journal
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    • v.18 no.3
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    • pp.272-281
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    • 2016
  • From the year 2000 on, Seoul has aimed to be a fashion city, and thus has been supporting young designers through Seoul Fashion Creative Studio, Generation Next, Le Dome, Concept Korea, etc. London is famous for nurturing young designers through the joint help of government, schools and industries: Alexander McQueen, Christopher Kane and Peter Pilotto are successful cases. Therefore, this research aims to suggest a direction for policies aimed at helping young designers in the international market, on the basis of London's nurturing programs and ideas from a literature review and case studies. The results are below. Firstly, a step-by-step supporting program is recommended. Secondly, long-lasting, sustainable programs are considered essential to support designers after the end of their contracts. Thirdly, practical assistance is preferred to monetary funding in order to lighten the designers' lot and in the interests of transparency. The mentoring service should be strengthened for the designers to eventually become independent. The support should be tailor-made according to items. Fourthly, the supporting programs should be promoted. Fifthly, government and industries should collaborate. Sixthly, 'de minimis' against overlapped support should be legislated. For these, the change of supporting method can be helpful; an independent administrative organisation plans and collects funds from governments and companies. Through these programs and any subsequent studies, Seoul could become a fashion city where young designers play active roles at a global level.

Investigation of Prior Technology and Development Case for Consecutive Excavation Technique of Shield TBM (연속굴착 쉴드 TBM 기술 관련 해외기술 및 개발사례 조사)

  • Mun-Gyu Kim;Jung-Woo Cho;Hyeong-seog Cha
    • Tunnel and Underground Space
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    • v.33 no.5
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    • pp.299-311
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    • 2023
  • Continuous excavation technologies are developed to improve the excavation rate of shield TBM. Continuous excavation is a technology that provides thrust to segments, excluding being installed one, to reduce tunneling downtime. This paper investigated the prior technology related to continuous excavation segments. The main technology was classified into helical segment, honeycomb segment, and conventional segment methods. The helical segment method has not been applied in actual construction yet, and the honeycomb segment method has not succeeded in commercialization. The continuous excavation method using conventional segments has been successfully demonstrated. The thrust force and operation method of the thrust jacks for the semi-continuous technology were analyzed. Continuous excavation TBM research is also progressing in Korea, and through the analysis of successful cases, the need to develop independent continuous excavation methods has been identified.

A Study on Growth and Development Information and Growth Prediction Model Development Influencing on the Production of Citrus Fruits

  • Kang, Heejoo;Lee, Inseok;Goh, Sangwook;Kang, Seokbeom
    • Agribusiness and Information Management
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    • v.6 no.1
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    • pp.1-11
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    • 2014
  • The purpose of this study is to develop the growth prediction model that can predict growth and development information influencing on the production of citrus fruits. The growth model was developed to predict the floral leaf ratio, number of fruit sets, fruit width, and overweight fruits depending on the main period of growth and development by considering the weather factors because the fruit production is influenced by weather depending on the growth and development period. To predict the outdoor-grown citrus fruit production, the investigation result for the standard farms is used as the basic data; in this study, we also understood that the influence of weather factors on the citrus fruit production based on the data from 2004 to 2013 of the outdoor-grown citrus fruit observation report in which the standard farms were targeted by the Agricultural Research Service and suggested the growth and development information prediction model with the weather information as an independent variable to build the observation model. The growth and development model for outdoor-grown citrus fruits was assumed by using the Ordinary Least Square method (OLS), and the developed growth prediction model can make a prediction in advance with the weather factors prior to the observation investigation for the citrus fruit production. To predict the growth and development information of the production of citrus fruits having a great ripple effect as a representative crop in Jeju agriculture, the prediction result regarding the production applying the weather factors depending on growth and development period could be applied usefully.