• Title/Summary/Keyword: the Far East

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The Inhibitory Effects of Glycyrrhiza uralensis on human Platelet Aggregation and Thrombus Formation

  • Seung Na Ko;Ji Won Son;Gyu Ri Kim;Min Seon Kim;Yea Jin Lee;Seung Ju Kim;Ji Hyeon Shin;Da In Jo;Woo Young Bok;Hye Gyo Oh;Hyuk-Woo Kwon
    • Biomedical Science Letters
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    • v.29 no.4
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    • pp.242-248
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    • 2023
  • Platelets are activated at the sites of vascular injury by a number of molecules, including adenosine diphosphate, collagen and thrombin. The full platelet aggregation is absolutely essential for the normal hemostasis. Glycyrrhiza glabra is a well-known medicinal herb that grows in various parts of the world and is known to have various effects such as antioxidant, anti-inflammatory, anti-atherogenic, anti-osteoporotic and skin-whitening. However, the platelet inhibitory effect of Glycyrrhiza glabra extract (GGE) has not been identified. In this study, we investigated if GGE inhibited platelet aggregation. We observed that GGE inhibited collagen-induced platelet aggregation, Ca2+ mobilization, and thromboxane A2 generation. In addition, GGE suppressed phosphorylation of phosphatidylinositol-3 kinase (PI3K), Akt and elevated phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R), vasodilator stimulated phosphoprotein (VASP). Taken together, GGE showed strong antiplatelet effects and may be used to block platelet-mediated cardiovascular diseases.

Main Regularities of Eco-geographical Differentiation in Endemic Element of the Russian Far East Flora

  • Kozhevnikov, Andrey Evhenjevicz
    • Korean Journal of Plant Taxonomy
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    • v.37 no.4
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    • pp.363-386
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    • 2007
  • Endemic element of the Russian Far East (RFE) flora includes 497 species of 150 genera and 46 families. The level of endemism in structure of regional natural flora reaches 11.1% as a whole, and in structure of its native fraction - 13.1%. As a result of chorologic and ecocenotic analysis of RFE flora endemic element it is revealed that it consists of 8 main geographical groups and 7 main floristic complexes. The largest number of endemic species is concentrated in Arctic - Alpine & Montane (140, 28.2%), Forest (107, 21.5%) and Maritime (88, 17.7%) floristic complexes as well as in Russian Far East - West-Pacific (136, 27.4%), Japan Sea (88, 17.7%) and North-East-Asian - Beringian (69, 13.9%) geographical groups. It's possible to distinguish three main areas with similar eco-geographical differentiation of endemics on RFE as follows: (1) North-East Asia sector of RFE which North-East-Asian - Beringian and Maritime Okhotia - Beringian geographical groups approximately correspond to, (2) Continental part of East Asia sector of RFE (West - Okhotian, Amur - Okhotian, Amur - Ussirian, Okhotsk Sea and Japan Sea groups) and (3) Oceanic part of East Asia sector (Russian Far East - West Pacific group). Taxonomical variety of RFE endemics on these territories makes up accordingly (1) - 99 species (19.9%), (2) - 259 (52.8%) and (3) - 136 (27.4%).

The Implementation of DMX-512 Control Software based on Windows for Effective LED Control (효과적으로 LED를 제어하기 위한 Windows기반의 DMX512 컨트롤 소프트웨어 구현)

  • Yang, Byung-Chul;Ji, Han-Kyul;Shin, Hyun-Taek;Ko, Kwang-Hyuk;Shin, Ye-Ho;Hyun, Deuk-Chang;Lee, Deok-Jin
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.1962_1963
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    • 2009
  • DMX-512 protocol is a lighting protocol which can control the various lighting fixtures by linking as networks. Recently many lighting fixtures corresponding to DMX-512 have been manufactured. The software which makes LED Control of lighting fixtures easy and simple, is proposed in this paper. The complicated interface and production method were improved and each mode was divided for simple production and reducing confusion of operator. The producing effects were confirmed by simulation results.

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A Design of 2.5kV Power IGBT for High Power (2.5kV급 Power IGBT 소자의 설계 및 제작에 관한 연구)

  • Kang, Ey-Goo;Ann, Byoung-Sup;Nam, Tae-Jin;Kim, Bum-June;Lee, Young-Hon;Chung, Hun-Suk
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.143-143
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    • 2009
  • 본 논문은 2500V급 planar type의 NPT(Nun-Punch Through)형 IGBT설계 및 제작에 앞서 IGBT(Insulated Gate Bipolar Transistor)소자가 갖는 구조적 변수가 전기적 특성 (Breakdown Voltage, Turnoff Time, Saturation Voltage, 등)결과에 미치는 영향을 분석하여 IGBT 소자가 갖는 구조적 손실을 최적화 하는데 목표를 두었다. 최적화의 진행은 공정 시뮬레이터인 Tsuprem4와 디바이스 분석 시뮬레이터인 MEDICI를 이용하여 소자가 갖는 각각의 parameter값이 전기적 특성에 미치는 영향을 분석함으로 진행 되어졌으며, 향후 고속철 등과 같은 대용량 산업에 기여할 것으로 판단된다.

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Freshwater Snails in the Southren Russian Far East

  • Prozorova, L.A.
    • The Korean Journal of Malacology
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    • v.13 no.2
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    • pp.97-108
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    • 1997
  • A review of literature and original data on content and distribution of gastropods, inhabition fresh bodies of water in the Southern Russian Far East is presented. The annotated list includes 98 species in 19 genera and 10 fimilies of Gastuopoda.

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The Study of Language Sign Classification using EEG of motor language area (운동언어영역의 EEG를 이용한 언어 부호 분류에 관한 연구)

  • Yang, Dong-Seuk;Jeong, Yong-Bae;Lee, June-Hwan;Cho, Han-Jin
    • Proceedings of the Korea Contents Association Conference
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    • 2011.05a
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    • pp.571-572
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    • 2011
  • 지금까지 뇌와 관련된 언어, 감정, 시각, 촉각 등 의학적 영역에서 뇌에 관한 연구들이 활발히 이루어져 왔다. 그러나 이러한 의학적, 심리학적 성과와 IT와의 융합 및 응용은 아직 초보적인 단계이다. 따라서 의학적으로 입증된 뇌 영역에서 발생하는 뇌파에 대해 보다 세밀한 분석 및 연구를 통해 실질적인 응용 가능한 BCI를 구현해보고자 한다.

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Design of 80 V Grade Low-power Semiconductor Device (80 V급 저전력 반도체 소자의 관한 연구)

  • Sim, Gwan Pil;Ann, Byoung Sup;Kang, Ye Hwan;Hong, Young Sung;Kang, Ey Goo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.26 no.3
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    • pp.190-193
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    • 2013
  • Power MOSFET and Power IGBT is develop in power savings, high efficiency, small size, high reliability, fast switching, low noise. Power MOSFET can be used high-speed switching transistors devices. Power MOSFET is devices the voltage-driven approach switching devices are design to handle on large power, power supplies, converters. In this paper, design the 80V MOSFET Planar Gate type, and design the Trench Gate type for realization of low on-resistance. For both structures, by comparing and analyzing the results of the simulation and characterization.

Voltage-Current-luminance Characteristics of Organic : Light-Emitting Diodes depending on Hole-Injection Buffer Layer (유기 발광 소자에서 정공 주입 버퍼층에 의한 전압-전류-휘도 특성)

  • Jeong Joon;Kim Tag-Yong;Ko Keel-Young;Lee Deok-Jin;Hong Jin-Woong
    • 한국컴퓨터산업교육학회:학술대회논문집
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    • 2003.11a
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    • pp.49-54
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    • 2003
  • In this work, we have seen the effect of hole-transporting layer in organic light-emitting diodes using N,N'-biphenyl-N,N'-bis-(3-methylphenyl)-[1,1'-biphenyl]-4,4'-diamine(TPD) and N,N'-biphenyl-N,N'-bis-(1-naphenyl)-[1,1'-biphenyl]-4,4'-diamine(NPB). NPB is regarded as a better hole trans porting material than TPD, since it has a higher glass transition temperature$(T_g)$. And current -voltage, luminance-voltage and external quantum efficiency of device were measured with the thickness variation of buffer layer using copper phathalocyanine(CuPc) and polytetrafluoroethylene (PTFE) at room temperature. We have obtained an improvement of External quantum efficiency when the CuPc 30[nm] and PTFE 1.0[nm] is used.

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Chronology and environment of the Palaeolithic and Neolithic cultures on the southern Russian Far East

  • Kuzmin, Yaroslav V.
    • The Korean Journal of Quaternary Research
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    • v.16 no.2
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    • pp.39-56
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    • 2002
  • The results of geoarchaeological studies of the prehistoric cultural complexes on the Russian Far East (Primorye, or Maritime Province; the Amur River basin; and Sakhalin Island) are presented. Upper Palaeolithic sites are dated to ca. 40,000-10,500 B.P. They existed during the mild climate of the Chernoruchie interstadial (ca. 40,000-21,000 B.P.); during harsh climate at the Last Glacial Maximum, ca. 20,000-18,000 B.P., in several places on the Russian Far East (Primorye, Amur River basin, and Sakhalin); and during climatic amelioration in the Late Glacial time, ca. 16,000-10,500 B.P. The earliest Neolithic sites, represented by Osipovka and Gromatukha cultures, existed at ca. 13,000-10,000 B.P. in the environment of coniferous forests with admixture of broadleaved taxa. Since ca. 8000 B.P., Neolithic cultures appeared in all of the Russian Far East. They existed until ca. 3000 B.P., first during the Holocene Climatic Optimum, ca. 8000-5000 B.P., in the environment of coniferous-broadleaved forests, and later, at ca. 5000-3000 B.P., in the environment of birch-oak and coniferous forests.

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