• 제목/요약/키워드: terpenoids

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A better understanding of traditional uses of Careya arborea Roxb.: Phytochemical and pharmacological review

  • Ambardar, Nupur;Aeri, Vidhu
    • 셀메드
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    • 제3권4호
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    • pp.28.1-28.7
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    • 2013
  • Careya arborea Roxb. (Lecythidaceae) is a significant medicinal plant known as kumbhi in Ayurveda. Though, most of the plant parts are used in traditional systems of medicine, bark and leaves constitute the important medicinal parts. The present review gives an account of the updated information on its phytochemical and pharmacological properties. The review reveals that numerous phytochemical constituents have been isolated from the plant possessing hepatoprotective, antioxidant, antimicrobial, anticoagulant, analgesic, antidiarrhoeal and various other important activities. Leaves are used in filaria, colic, loose motions and ulcers. Bark is used as an antipyretic, abortifacient, antipruritic and in smallpox, urinary discharges and rheumatic pain. Since last few decades, extensive exploration has been done to establish the biological activities and pharmacology of the extracts and plentiful chemical constituents including flavonoids, tannins, alkaloids, terpenoids and many other have been isolated.

Pentacyclic Triterpenoids from Mallotus apelta

  • Kiem, Phan-Van;Minh, Chau-Van;Huong, Hoang-Thanh;Nam, Nguyen-Hoai;Lee, Jung-Joon;Kim, Young-Ho
    • Archives of Pharmacal Research
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    • 제27권11호
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    • pp.1109-1113
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    • 2004
  • A new triterpene (1) and six known pentacyclic terpenoids (2-7) were isolated from the methanol extract of the dried leaves from Mallotus apelta. Based on the spectral and chemical evidence, their structures were determined to be 3$\alpha$-hydroxyhop-22(29)-ene (1), hennadiol (2), friedelin (3), friedelanol (4), epifriedelanol (5), taraxerone (6), and epitaraxerol (7).

Anticancer and Antiviral Effect of Some Triterpenes Isolated from the Natural Sources

  • Kim, Young-Sup;Choi, Sang-Un;Lee, Chong-Ock;Lee, Chong-Kyo;Ryu, Shi-Yong
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.138-139
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    • 2002
  • The diverse, widespread, and exceedingly numerous family of natural products constructed from five carbon building-units and so comprising compounds with $C_{5}$, $C_{10}$, $C_{15}$, $C_{20}$, ${\cdots}$, $C_{40}$ skeletons (together with a few higher members) are synoymously termed terpenes or terpenoids. Among the terpene classes, the triterpenes ($C_{30}$ skeletones) form the largest group and are widely distributed in the plant kingdom, either in the free state or as esters or glycosides, although a few important members found in the animal kingdom such as squalene and a number of tetracyclic component including lanosterol. (omitted)

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쑥에 들어 있는 生長 抑制物質의 作用 (Allelopathic Effects of Growth Inhibitor from Artemisia princeps var. orientalis)

  • Kil, Bong-Seop;Young-Sik Kim;Kyeong-Won Yun
    • The Korean Journal of Ecology
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    • 제14권2호
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    • pp.121-135
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    • 1991
  • A number of laboratory experimentes have performed to elucidate water-soluble of volatile substances from wormwood plant(artemisia princeps var. orientalis) as growth inhibitor or phytotoxicant. in germination tests with aqueous extracts of leaves, stems and roots of the wormwood plants, most tested species showed that relative germination ratio was inversely proportional to comcentration of the extracats. and seedling elongation and dry weight of the species were heavily inhibited with the extracts, incubated leaves, volatile substances of the leaves and soil underneath wormwood plants. gas Chromatography was employed to find out possible phytotoxic substances or growth inhibitors of wormwood leaves. ten substantes have isolated, and most of them were identified as terpenoids.

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Constituents from the Non-Polar Fraction of Artemisia apiacea

  • Lee, Sanghyun;Kim, Kyoung-Soon;Shim, Sang-Hee;Park, You-Mie;Kim, Bak-Kwang
    • Archives of Pharmacal Research
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    • 제26권11호
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    • pp.902-905
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    • 2003
  • Five compounds of terpenoids and coumarins were isolated from the non-polar fraction of Artemisia apiacea by open column chromatography. Their structures were elucidated as $\alpha$-amyrin (1), $\beta$-amyrin (2), $\beta$-sitosterol (3), 5,6,7-trimethoxycoumarin (4) and 6-methoxy-7,8-methylenedioxycoumarin (5) by chemical and spectroscopic analysis. This is the first report of the isolation of $\alpha$-amyrin, $\beta$-amyrin, 5,6,7-trimethoxycoumarin and 6-methoxy-7,8-methylene-dioxycoumarin from this plant.

Phytochemical constituent, percentage yield and phenolic content estimation of different solvent system of Carica papaya leaves

  • Sheneni, Victor Duniya;Usman, Oman Salifu;Musa, Quasim
    • 식품보건융합연구
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    • 제4권2호
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    • pp.17-23
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    • 2018
  • Carica papaya is an important medicinal plant used in the management of different disease conditions. Phytochemical screening was carried out using different chemical test, Percentage yield and total phenolic content was evaluated using Folin Ciocalteu method in different solvent system; methanol, ethanol, ethyl acetate, n-butanol and n-hexane respectively. The phytochemical screening of the studies showed the presence of flavonoids, saponins, tannins, terpenoids, glycosides, steroids, carbonhydrate, anthraquinone and alkaloids. The percentage yield of crude extract and total polyphenol content was high in methanol, ethanol and ethyl acetate when compared with n-butanol and n-hexane. The studies show that Carica papaya leave extracts is a potent source of secondary metabolites. The use of the plant in the management of diseases is justified.

한국산 주목의 세포배양에 의한 Taxane 유도체의 생산 (I) (Production of Taxane Derivatives by Cell Culture of Korean Taxus Species (I))

  • 김유선;신승원
    • 생약학회지
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    • 제27권3호
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    • pp.262-266
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    • 1996
  • Undifferentiated callus were induced from the young leaves of Taxus cuspidata by treatment with various combinations of plant growth hormones. The effects of light and culturing temperature on production of baccatin III, the precursor of taxol, were studied. The contents of baccatin III in the cultured callus were analysed by HPLC. The illumination of fluorescence and administration of isoleucine, one of the possible substrates in biosynthesis of terpenoids, to the culturing media increased the production of baccetin III.

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Antibiotic Components from the Rhizomes of Curcuma zedoaria

  • Jeong, Choon Sik;Shim, Sang Hee
    • Natural Product Sciences
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    • 제21권3호
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    • pp.147-149
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    • 2015
  • Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay. Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.

Pytochemical Constituents of the Aerial Parts from Solidago virga-aurea var. gigantea

  • Choi, Sang-Zin;Choi, Sang-Un;Lee, Kang-Ro
    • Archives of Pharmacal Research
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    • 제27권2호
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    • pp.164-168
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    • 2004
  • The chromatographic separation of the MeOH extract of the aerial parts of Solidago virga-aurea var. gigantea $M_{IQ}$ . (Compositae) led to the isolation of six terpenoids and four phenolic compounds, trans-phytol (1), ent-germacra-4(15),5,10(14 )-trien-1$\alpha$-ol (2), $\beta$-amyrin acetate (3), ent-germacra-4(15),5,10(14)-trien-1$\beta$-ol (4), $\beta$-dictyopterol (5), oleanolic acid (6), kaempferol (7), kaempferol-3-O-rutinoside (8), methyl 3,5-di-O-caffeoyl quinate (9), and 3,5-di-O-caffeoyl quinic acid (10). Their structures were established by chemical and spectroscopic methods. Compounds 4, 5, and 10 showed moderate cytotoxicity against five cultured human tumor cell lines in vitro with its E $D_{50}$ values ranging from 1.52∼18.57 $\mu\textrm{g}$/mL.L.