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Pytochemical Constituents of the Aerial Parts from Solidago virga-aurea var. gigantea  

Choi, Sang-Zin (Natural Products Laboratory, College of Pharmacy, SyngKyunKwan University)
Choi, Sang-Un (Korea Research Institute of Chemical Technology)
Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, SyngKyunKwan University)
Publication Information
Archives of Pharmacal Research / v.27, no.2, 2004 , pp. 164-168 More about this Journal
Abstract
The chromatographic separation of the MeOH extract of the aerial parts of Solidago virga-aurea var. gigantea $M_{IQ}$ . (Compositae) led to the isolation of six terpenoids and four phenolic compounds, trans-phytol (1), ent-germacra-4(15),5,10(14 )-trien-1$\alpha$-ol (2), $\beta$-amyrin acetate (3), ent-germacra-4(15),5,10(14)-trien-1$\beta$-ol (4), $\beta$-dictyopterol (5), oleanolic acid (6), kaempferol (7), kaempferol-3-O-rutinoside (8), methyl 3,5-di-O-caffeoyl quinate (9), and 3,5-di-O-caffeoyl quinic acid (10). Their structures were established by chemical and spectroscopic methods. Compounds 4, 5, and 10 showed moderate cytotoxicity against five cultured human tumor cell lines in vitro with its E $D_{50}$ values ranging from 1.52∼18.57 $\mu\textrm{g}$/mL.L.
Keywords
Solidago virga-aurea var. gigantea $M_{IQ}$; Compositae; Terpenoid; Flavonoid; Quinic acid; Cytotoxicity;
Citations & Related Records

Times Cited By Web Of Science : 16  (Related Records In Web of Science)
Times Cited By SCOPUS : 23
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