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Phytochemical constituent, percentage yield and phenolic content estimation of different solvent system of Carica papaya leaves

  • Received : 2018.09.10
  • Accepted : 2018.09.20
  • Published : 2018.09.30

Abstract

Carica papaya is an important medicinal plant used in the management of different disease conditions. Phytochemical screening was carried out using different chemical test, Percentage yield and total phenolic content was evaluated using Folin Ciocalteu method in different solvent system; methanol, ethanol, ethyl acetate, n-butanol and n-hexane respectively. The phytochemical screening of the studies showed the presence of flavonoids, saponins, tannins, terpenoids, glycosides, steroids, carbonhydrate, anthraquinone and alkaloids. The percentage yield of crude extract and total polyphenol content was high in methanol, ethanol and ethyl acetate when compared with n-butanol and n-hexane. The studies show that Carica papaya leave extracts is a potent source of secondary metabolites. The use of the plant in the management of diseases is justified.

Keywords

References

  1. Amin, I., Zamaliah, M.M., & Chin, W.F. (2004). Total antioxidant activity and phenolic content in selected vegetables. Food Chemistry,87(4), 581- 586. https://doi.org/10.1016/j.foodchem.2004.01.010
  2. Bruce, S., & Peter, C.A. (2008). Handbook of environmental physiology of fruit crops (1st ed.). New York, NY: Landmark.
  3. Chaouche, M.D., Haddouchi, F., & Ksouri, R. (2013). Antioxidant activity profiling by spectrophotometric methods of phenolic extract of Prasium majus. Free Radicals and Antioxidants, 3(2), 43-46. https://doi.org/10.1016/j.fra.2013.03.004
  4. Chukwuka, K.S., Ikheloa, J.O., Okonko, I.O., Moody, J.O., & Mankinde, T.A. (2011). The antimicrobial activities of some medicinal plants on Escherichia colias an agent of diarrhea in livestock. Advanced Applied Science Research, 2(11), 37-48.
  5. Gross, D. (2003). Papaya: a tantalising taste of the Tropics. Tucson, AZ: University of Arizona Cooperative Extension.
  6. Doss, A., Mohammed, H., & Dhanabalan, R. (2009). Antibacterial activity of tannins from the leaves of Solanum trilobatum Linn. Phytochemistry, 2(2), 6774- 6846.
  7. Edeoga, H.O., Okwu, D.E., & Mbaebie. B.O. (2005). Phytochemical constituents of some Nigeria medical plants. African Journal of Biotechnology, 4(7), 685-688. https://doi.org/10.5897/AJB2005.000-3127
  8. Edeoga, H.O., & Eriata, D.O. (2001). Alkaloid, Tannin and Sapnin contents of some medicinal plants. Journal of Medicinal Aromatic Plant Science, 12(2), 344-349.
  9. Firn, R. (2010). Nature's Chemicals. Oxford, OXF: Oxford University Press.
  10. Gopakumar, G.N., Cherupally, K., & Krishnan, N. (2013). Radioprotective effects of Gallic Acid in Mice. Biomedical Research International, 3(13), 17-21.
  11. Hamburger, M., & Hostettmann, K. (1991). Bioactive plants link between Phytochemistry and Medicine. Phytochemistry, 6(3), 3864-3874.
  12. Harborne, J.B., & Williams, C.A. (2000). Advances in flavonoid research since 1992. Phytochemistry, 5(5), 481-504.
  13. Kasote, D.M. (2013). Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications. Biofactors, 3(9), 392-06.
  14. Makkar, H.P. (2007). Bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems. Journal of animal, 1(9), 1371-1391. https://doi.org/10.1017/S1751731107000298
  15. McLanghlin, J.L., Ratanyake, S., Rupprecht, J.K., & Potter, W.M. (1992). Evaluation of various parts of the pawpaw tree. Journal of Economical Entomoogy, 4(5), 2353-2356.
  16. Mead, R., & Curnow, R.N. (1982). A simple statistical method in Agricultural and Experimental Biology. Chapman Hall London, 3(2), 46.
  17. Messina, M.J. (1999). Hypolipidemic activity on experimental hypercholesterolemia in rat. Phytomedicine, 6(3), 10-5.
  18. Odebiyi, O., & Sofowora, E.A. (1978). Phytochemical screening of Nigerian medicinal plants. Phytomedicine, 4(1), 41-234. https://doi.org/10.1016/S0944-7113(97)80026-8
  19. Patrick, E.E., Atangwho, I.J., Eyong, U.E., & Egbung, G.E. (2008). Antidiabetic efficacy of Combined Extracts from two continental plants. American Journal of Biochemistry and Biotechnology, 4(3), 239-244. https://doi.org/10.3844/ajbbsp.2008.239.244
  20. Peter, R.N. (1991). Genetic sources of temperate fruit and nut trees. International Journal of nutrition, 16(6), 567-600.
  21. Quang-Vinh, N., & Jong-Bang, E. (2011). Antioxidant activity of solvent extracts from Vietnamese medicinal plants. Journal of Medicinal Plants Research, 5(13), 2798.
  22. Quideau, S., Deffieux, D., Douat‐Casassus, C., & Pouysegu, L. (2011). Plants polyphenols chemical properties. Asian International Journal, 50(3), 586-621.
  23. Shrikumar, S., & Ravi, R.K. (2007). Approaches towards development and promotion of herbal drugs. Journal of phymacognosical Research, 1(4), 180-184.
  24. Tedong, L., Dimo, T., Dzeufiet, P.D.D., Asongalem, A.E., & Sokeng, D.S.P. (2006). Antihyperglycemic and renal protective activities of Anacardiumoccidentale leaves in streptozotocin induced diabetic rats. African Journal of Traditional medicine, 3(1), 23-35.
  25. Trease, G.E., & Evans, M.D. (1989). Textbook of Pharmacognosy (13th ed). London: H. Bailliere Book Catalog.
  26. W.H.O. (2000). General guidelines for methodologies on research and evaluation of traditional medicine.
  27. Zohra, M. (2011). Impact of solvent extraction type on total polyphenols content and biological actability from Tamarix aphylla. International Journal of Pharmacy and Biology, 2(1), 609- 615.