• 보건의료산업학회지
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• 제13권4호
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• pp.19-31
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• 2019

Objectives: The purpose of this study was to analyze research trends in age-friendly research and suggest directions for future research. Methods: For this study, 112 articles related to age-friendly research were selected, from 605 published articles in The Korean Journal of Health Service Management (2007-2018). Content analysis and text network analysis were conducted using SPSS 23.0 and NetMiner 4. Results: First, 2 authors (30.4%) and 4 keywords (45.5%) were the most studied. Most of the studies used quantitative research (93.8%). Primary data (61.9%) and SPSS (77.7%) were the most used for analysis. Second, there were seven common keywords in the top 10 in all the centralities. They were Elderly, Geriatric Hospital, Depression, Care Workers, Long-Term Care Facilities, Experience, and Attitude. Conclusions: This study shows the need for diversity of research topics, subjects, research methods, and analytical tools in future age-friendly related studies. In addition, it suggests activating convergence research in this field linked to various industries and services.

• 한국약용작물학회지
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• 제10권1호
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• pp.29-36
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• 2002

예로부터 우리나라와 중국을 비롯한 동양에서는 음양곽을 강정제 및 정력강화제로 사용되어왔다. 본 연구는 흰쥐에게 장기간 음양곽 물 추출물을 공급하고(0.025%,w/v) 노화에 따른 생리적인 변화와 간의 이물질 대사 효소군의 활성도에 미치는 영향을 조사하였다. 흰쥐에 음양곽의 물 추출물 공급으로 특이한 질병은 발견되지 않았으나 24개월에서 간과 신장의 무게는 대조군에 비해 다소 증가하였으며 혈청의 glutamate-oxaloacetate transminase와 glutamate-pyruvate transminase 활성도도 증가하였다 간의 이물질 대사효소 중 cytochrome P450 NADPH-cytochrome P450 reductase, benzphetamine N-demethylase ethoxycoumarine O-deethylase, glutathione S-transferase의 활성도는 두 그룹 모두 노화에 따라 감소하였으며, 음양곽 물 추출물 투여에 의해 감소현상이 악화되었다. 간의 cytochrome B5의 함량과 NADH cytochrome b5 reductase의 활성도도 노화에 따라 감소되었으나 같은 나이에서 두 그룹간의 뚜렷한 차이를 보이지 않았다. 이상의 결과로 보아 흰쥐에 장기간 음양곽 물 추출물을 공급은 노년기에 노화에 따라 감소하는 간의 이물질 대사 기능에 부담을 수도 있다는 것을 암시해 준다.

• Clinics in Shoulder and Elbow
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• 제26권3호
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• pp.231-237
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• 2023

Background: In the past decade, the number of anatomic total shoulder arthroplasty (aTSA) procedures has steadily increased. Patients over 65 years of age comprise the vast majority of recipients, and outcomes have been well documented; however, patients are opting for definitive surgical treatment at younger ages.We aim to report on the effects of age on the long-term clinical outcomes following aTSA. Methods: Among the patients who underwent TSA, 119 shoulders were retrospectively analyzed. Preoperative and postoperative clinical outcome data were collected. Linear regression analysis (univariate and multivariate) was conducted to evaluate the associations of clinical outcomes with age. Kaplan-Meier curves and Cox regression analyses were performed to evaluate implant survival. Results: At final follow-up, patients of all ages undergoing aTSA experienced significant and sustained improvements in all primary outcome measures compared with preoperative values. Based on multivariate analysis, age at the time of surgery was a significant predictor of postoperative outcomes. Excellent implant survival was observed over the course of this study, and Cox regression survival analysis indicated age and sex to not be associated with an increased risk of implant failure. Conclusions: When controlling for sex and follow-up duration, older age was associated with significantly better patient-reported outcome measures. Despite this difference, we noted no significant effects on range of motion or implant survival. Level of evidence: IV.

• Archives of Plastic Surgery
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• 제44권3호
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• pp.202-209
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• 2017

Background No consensus exists on the optimal treatment protocol for orofacial clefts or the optimal timing of cleft palate closure. This study investigated factors influencing speech outcomes after two-stage palate repair in adults with a non-syndromal complete unilateral cleft lip and palate (UCLP). Methods This was a retrospective analysis of adult patients with a UCLP who underwent two-stage palate closure and were treated at our tertiary cleft centre. Patients ${\geq}17$ years of age were invited for a final speech assessment. Their medical history was obtained from their medical files, and speech outcomes were assessed by a speech pathologist during the follow-up consultation. Results Forty-eight patients were included in the analysis, with a mean age of 21 years (standard deviation, 3.4 years). Their mean age at the time of hard and soft palate closure was 3 years and 8.0 months, respectively. In 40% of the patients, a pharyngoplasty was performed. On a 5-point intelligibility scale, 84.4% received a score of 1 or 2; meaning that their speech was intelligible. We observed a significant correlation between intelligibility scores and the incidence of articulation errors (P<0.001). In total, 36% showed mild to moderate hypernasality during the speech assessment, and 11%-17% of the patients exhibited increased nasalance scores, assessed through nasometry. Conclusions The present study describes long-term speech outcomes after two-stage palatoplasty with hard palate closure at a mean age of 3 years old. We observed moderate long-term intelligibility scores, a relatively high incidence of persistent hypernasality, and a high pharyngoplasty incidence.

• 대한유전성대사질환학회지
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• 제17권1호
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• pp.18-23
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• 2017

${\beta}$-ureidopropionase 결핍증(${\beta}$-UPD)은 UPB1 유전자 변이에 의한 피리미딘 대사 이상에 의해 생기는 매우 드문 상염색체 열성 유전 질환으로 현재까지 전 세계에서 30여명 정도만 보고되었다. ${\beta}$-UPD는 무증상인 경우부터 심한 발달 지연, 소두증, 발작, 인지 저하의 증상을 보이는 경우까지 다양하다. 국내에서 진단된 유일한 ${\beta}$-UPD 여자 환자는 8세 10개월에 targeted next-generation sequencing 검사로 UPB1 유전자 변이를 확인 한 후, Sanger sequencing을 통해 확진하였다. 환자는 성장 장애, 발단 지연, 소두증, 반복되는 감염 및 난치성 뇌전증 증상을 보였으며, 11세 5개월에 원인 미상으로 갑자기 사망하였다. 이에 저자들은 ${\beta}$-UPD 환자의 장기간의 임상경과에 대해 보고하는 바이다.

• 한국콘텐츠학회논문지
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• 제14권7호
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• pp.346-355
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• 2014

본 연구의 목적은 시설거주 여성노인의 일상생활동작이 반영된 기초신체활동을 측정하여 대상자들의 기초신체활동의 기본적인 필수 측정요소와 측정항목을 제시하기 위함이다. 대상자는 대전과 충남에 소재한 장기요양시설 4곳의 만 65세 이상 여성노인 105명이며, 일상생활동작이 반영된 8개 항목(악력, 스텝 테스트, 의자에서 앉았다 일어나기, 한발 서기, 기능적 팔 뻗기, 8자 보행, 5m 보행, 일어서고 걷기)을 측정하였다. 자료는 평균과 표준편차, 요인분석, ANOVA, 그리고 피어슨의 상관관계로 분석하였다. 연령집단 간각 종목의 평균을 분석한 결과 연령이 증가함에 따라 각 측정항목의 결과에 유의한 차이를 나타냈다. 8개 측정항목은 요인분석을 통해 근력과 이동능력 두 영역으로 제시하였다. 시설거주 여성노인에게 중요한 체력요소인 이 근력과 이동능력 영역은 연령이 증가할수록 모두 유의하게 감소하였다. 따라서 시설거주 여성노인의 운동을 위한 간호전략에 있어 근력 및 이동능력의 요소가 고려되어야 하며, 이 두 영역에 대한 측정항목 또한 객관적인 지표가 마련되어야 한다.

• 한국약용작물학회지
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• 제15권5호
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• pp.352-356
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• 2007

The present study was investigated the anti-oxidative effects of aloe vera ingestion on brain and kidney in aged rats by monitoring several oxidative-related parameters. Male specific pathogen-free Fischer 344 rats were randomly divided into four groups of five rat each: Group A was fed test chow without aloe supplementation; Group B was fed a diet containing a 1% freeze-dried aloe filet; Group C was fed a diet containing a 1% charcoal-processed, freeze-dried aloe filet; and Group D was fed a diet containing a charcoal-processed, freeze-dried, whole leaf aloe in drinking water. Analyses of tissues were done at 4 months and 16 months of age. Results showed that a long-term intake of aloe, regardless of the preparation used, enhanced antioxidant defenses against lipid peroxidation, as indicated by reduced phosphatidylcholine hydroperoxide levels in both brain and kidney. The additional benefit of aloe intake on the anti-oxidative action was evidenced by enhanced superoxide dismutase and catalase activity in all aloe-ingested groups. Another beneficial effect of aloe shown in this study, although not an anti-oxidative parameter, was its cholesterol-lowering effect as detected in brain and kidney with significant decreases at age16 months of aloe-fed rats. Based on these findings, we conclude that a long-term dietary aloe supplementation modulated the anti-oxidative defense systems and cholesterol level.

• 한국지반공학회지:지반
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• 제14권2호
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• pp.21-30
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• 1998

쓰레기 매립지는 쓰레기 고형물이 장기간에 걸쳐 생물학적으로 분해됨으로 말미암아 상당한 양의 침하가 유발되는 독특한 침하특성을 갖고 있다. 분해에 의한 총 압축량은 분해가능한 쓰레기의 고형물 함량 및 매립연한에 크게 의존하며. 매립지 침하의 안정화 속도는 분해조건에 의존한다. 쓰레기 매립지의 이러한 독특한 침하거동을 규명하기 위하여 제안되었던 침하모델을 매립 연한이 서로 다른 쓰레기 매립지 침하자료들에 대하여 적용하였다. 모델 변수 값들이 각각 구해 졌으며, 그 경향들이 분석되었다. 쓰레기 매립지의 장기 침하 양상이 제안된 모델에 의해 잘 예측될 수 있으며, 매립연한 및 두개의 적합한 설계변수에 근거하여 잔존 침하량을 예측할 수 있다.

• 대한치과기공학회지
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• 제20권1호
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• pp.61-89
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• 1998

Having taken as cause of dental technicians separation from their service a variety of individual idiosyncrasies, function-related factors, external environment factors, functional satisfaction, organizational commitment, and intention to remain, the present study conducted a mail questionnaire poll and interviews on those dental technicians who are mow in the service with private dental technical workshops and dental technical workshops in general hospitals and private dental clinics. The resultant findings from analysis of the repondent's general characteristics of cause of separation form service were revealed, as follows : 1) It was shown that the higher the academic career, the considerably higher cause of position commitment among causes of individual idio-syncrasies, reflecting a statistically significant result(P<0.05) 2) The less the number of working hours as viewed from the average number of working hours per day, the higher the positive emotion, reflecting a significant relation(P<0.01) 3) Causes from performing duties among function-related causes diclosed a statistically significant relation among marital status, career, monthly income, and positions(P<0.01) 4) Causes from wages showed a statistically significant relation in the average number of working hours per day(P<0.01), monthly income(P,0.05), and positions(P<0.05) 5) Causes from supervision exposed a significant relation in workplaces(P<0.01) 6) Causes from promotion represented a significant relation in positions(P<0.001) 7) Causes from opportunnities for taking a job as seen from external environment causes also disclosed a statistically significant relation in workplaces(P<0.05) 8) Reponsibility for family sustenace reflected a statistically significant relation in sex, age, marital status, career, monthly income, work fields, term of employment, positions, and experience of separation(P<0.001) 9) Functional satisfaction showed a statistically significant relation in marital status, career, monthly income, and the average number of hours a day(P<0.05) 10) Oraganizational commitment disclosed a statistically significant relation in work experience, monthly income, term of employment, positions(P<0.05) and the average number of working hours a day(P<0.001) 11) The intention to remain indicated a statistically significant relation in age, marital status, work experience, monthly income, positions(P<0.001) and term of employment. the average number of working hours a day(P<0.01), and in the performing work field(P<0.05)

• Clinical and Experimental Pediatrics
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• 제61권3호
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• pp.78-83
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• 2018

Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables. Methods: Nineteen preterm infants with feeding desaturation (group 1) and 19 age-matched full-term infants (group 2) were evaluated. Oromotor function was evaluated using video recording. The root-mean-square (RMS) envelope of the electromyography signal was calculated to quantify the activities of muscles involved in respiration. The differences in RMS between both groups and the correlation with clinical variables including gestational age (GA), birth weight (BW), and Apgar scores (AS) at 1 and 5 minutes after birth were evaluated. Results: The RMS values of the diaphragm (RMS-D) and rectus abdominis (RMS-R) were significantly greater in group 1 compared to group 2, and the 1- and 5-min AS were significantly lower in group 1 compared to group 2. RMS-D and RMS-R were inversely correlated with GA, BW, 1- and 5-min AS in all infants. Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.