• Title/Summary/Keyword: targeting efficiency

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Comparison between Bacterial Culture Method and Multiplex PCR for Identification of Fusobacterium nucleatum and Actinobacillus actinomycetemcomitans from the Dental Plaques (치면세균막내의 Fusobacterium nucleatum과 Actinobacillus actinomycetemcomitans의 동정을 위한 세균배양법 및 Multiplex PCR법의 비교)

  • Kim, Hwa-Sook;Lim, Sun-A
    • Journal of dental hygiene science
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    • v.9 no.2
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    • pp.249-255
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    • 2009
  • This study was carried out for the purpose of comparing bacterial culture method, single PCR, and multiplex PCR for identification of F. nucleatum and A. actinomycetemcomitans in subgingival plaque of adult periodontitis. Targeting 20 patients with adult periodontitis, the subgingival plaque was collected in teeth, respectively, for #16, #36, #44. A bacillus was cultivated by painting it over the solid selective media of F. nucleatum and A. actinomycetemcomitans. Bacterial species were detected in 0 tooth with 12 pieces, respectively. Through single PCR and multiplex PCR, the positive reaction was indicated in 43 teeth with 45 pieces, respectively, as for F. nucleatum, and in 1 tooth with 4 pieces, respectively, as for A. actinomycetemcomitans. In the comparative analysis between bacterial identification methods. F. nucleatum showed the more statistically significant difference(p=0.0(0) in comparison between single PCR and multiplex PCR. Even A. actinomycetemcomitans was indicated significantly(p=0.067) in a case that is based on 0.1 in significant level in the comparison between single PCR and multiplex PCR. In conclusion, as a result of comparing the bacterial identification methods, the detection frequency was indicated to be higher in PCR than in bacterial culture method. Single PCR and multiplex PCR showed the mutually similar detection frequency. Accordingly, given thinking of economic efficiency, quickness, and reduction in labor force, it is thought to be more efficient method to use single PCR as the bacterial identification method.

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Watershed Water Quality Management Plan Using SWAT and Load Duration Curve (SWAT와 부하지속곡선을 이용한 유역 수질 관리방안)

  • KAL, Byung-Seok;CHO, So-Hyun;PARK, Chun-Dong;MUN, Hyun-Saing;JOO, Yong-Eun;PARK, Jae-Beom
    • Journal of the Korean Association of Geographic Information Studies
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    • v.24 no.3
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    • pp.41-57
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    • 2021
  • This study evaluated the application of water quality management measures using the SWAT model and the effectiveness of the measures using the load duration curve targeting the Seohwacheon watershed located upstream of Daecheongho. As water quality management measures, artificial wetlands, reduction of neglected livestock, reduction of runoff from greenhouses, restoration of ecological rivers, application of LID technology, and management of point sources were applied. The applied technology evaluated the efficiency of water quality improvement measures by using the target water quality excess rate and the degree of load reduction for each sulfur through the load duration curve. The load duration curve was created by creating a long-term flow duration curve using SWAT and multiplying it by the target water quality. For the target water quality, the value corresponding to the 60th percentile was set as the target water quality using the 10-year data from the Okcheoncheon water quality observation point located in the downstream of Seohwacheon. Through this study, it was possible to confirm the applicability of various water quality measures through the SWAT model, and to examine the applicability of each period according to the sulfur through the load retention curve.

Development of PLGA Nanoparticles for Astrocyte-specific Delivery of Gene Therapy: A Review (별아교세포 선택적 유전자 치료전달을 위한 PLGA 나노입자 개발)

  • Shin, Hyo Jung;Lee, Ka Young;Kwon, Kisang;Kwon, O-Yu;Kim, Dong Woon
    • Journal of Life Science
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    • v.31 no.9
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    • pp.849-855
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    • 2021
  • Recently, as nanotechnology has been introduced and used in various fields, the development of new drugs has been accelerating. Nanoparticles have maintained blood drug concentration for extended periods of time with a single administration of the drug. The drug can then be selectively released only at the pathological site, thereby reducing side effects to other non-pathological sites. In addition, nanoparticles can be modified for selective target sites delivery for other specific diseases, with polymers being widely used in the manufacture of these nanoparticles. Poly (D,L-lactic-co-glycolic acid ) (PLGA) is one of the most extensively developed biodegradable polymers. PLGA is widely used in drug delivery for a variety of applications. It has also been approved by the FDA as a drug delivery system and is widely applied in controlled release formulations, such as in gene therapy treatments. PLGA nanoparticles have been developed as delivery systems with high efficiency to specific cell types by using passive and active targeting methods. After the development of a drug delivery system using PLGA nanoparticles, the drug is selectively delivered to the target site, and the effective blood concentration for extended periods of time is optimized according to the disease. In this review paper, we focus on ways to improve cell-specific treatment outcomes by examining the development of astrocyte selective nanoparticles based on PLGA nanomaterials for gene therapy.

Secure File Transfer Method and Forensic Readiness by converting file format in Network Segmentation Environment (망분리 환경에서 파일형식 변환을 통한 안전한 파일 전송 및 포렌식 준비도 구축 연구)

  • Han, Jaehyeok;Yoon, Youngin;Hur, Gimin;Lee, Jaeyeon;Choi, Jeongin;Hong, SeokJun;Lee, Sangjin
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.29 no.4
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    • pp.859-866
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    • 2019
  • Cybersecurity attack targeting a specific user is rising in number, even enterprises are trying to strengthen their cybersecurity. Network segmentation environment where public network and private network are separated could block information coming from the outside, however, it is unable to control outside information for business efficiency and productivity. Even if enterprises try to enhance security policies and introduce the network segmentation system and a solution incorporating CDR technology to remove unnecessary data contained in files, it is still exposed to security threats. Therefore, we suggest a system that uses file format conversion to transmit a secure file in the network separation environment. The secure file is converted into an image file from a document, as it reflects attack patterns of inserting malicious code into the document file. Additionally, this paper proposes a system in the environment which functions that a document file can keep information for incident response, considering forensic readiness.

Analysis of the Structural Characteristics of the Chungnam Display Industry (충남 디스플레이 산업의 구조적 특성 분석)

  • Kim, Dae-Jung;Ko, Kyoung-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.620-626
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    • 2021
  • The purpose of this study is to examine the characteristics and industrial structure and to present a future vision through analysis of industrial agglomeration, growth, and industrial efficiency targeting the Chungnam display industry nurtured by regional industrial policies since 2002. The industrial scale and aggregate status were analyzed through the business scale quotient and location quotient, and the growth and pace of structural change in the industry were analyzed through the industrial growth rate and change of industrial structure. Analysis results found the display industry shows its solid status based on industrial agglomeration. The RLQ, added value ratio, and employment coefficient have a relatively high comparative advantage. However, the growth rate has declined, and the pace of structural change has become lower. The regional competitiveness has been deteriorating. It is necessary to develop strategies to help the industry evolve into a convergence display industry to secure competitiveness by forming value chains. The regional industrial policy 'Regional Innovation Growth Plan' should be utilized to foster local industries that consider the regional characteristics and development directions and to promote the shared growth of related subsidiary industries through fostering specialized complexes for materials, parts, and equipment.

A Study on Traditional Darangyi-Rice Terrace as Design Factors of Agricultural Landscape (농업경관의 디자인적 요소인 전통다랑논 조사연구)

  • Son, Ho-Gi;Kim, Sang-Bum;Kim, Eun-Ja;Rhee, Sang-Young
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.29 no.1
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    • pp.157-165
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    • 2011
  • This study is to be used as a fundamental material of rural amenity resources researches, such as excavating, establishing and modifying national agricultural landscape resources, so as to efficiently manage them. It is carried out with targeting traditional Darangyi-Rice terrace which has design factors of agricultural landscape resources. We have set up the standard range with practicable similar standard(Marginal Farmland and Less Favored Areas and etc), those of Japan, and the results of analyzing the characteristics of Darangyi-Rice terrace already known. As a result of the field investigation, it has been revealed that a great deal of Darangyi-Rice terrace are being used for not corresponding purposes, or damaged and disappeared. For preserving and well-managing Darangyi-Rice terrace as a rural landscape resource which has rural design factors, it should be advanced detailed and accurate studies on present conditions and changes of Darangyi-Rice terrace, with researches on significances, values, utilities and economical efficiency of Darangyi-Rice terrace by regions. In addition, we utilized various spatial imagery data in the researching process. Consequently, it is concluded that if high resolution imagery data is used, it can establish rather minute and accurate large-scale DB, and monitor elaborate changes as well. It is therefore thought that its application can be higher as actualizing DB hereafter.

Model Inversion Attack: Analysis under Gray-box Scenario on Deep Learning based Face Recognition System

  • Khosravy, Mahdi;Nakamura, Kazuaki;Hirose, Yuki;Nitta, Naoko;Babaguchi, Noboru
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.3
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    • pp.1100-1118
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    • 2021
  • In a wide range of ML applications, the training data contains privacy-sensitive information that should be kept secure. Training the ML systems by privacy-sensitive data makes the ML model inherent to the data. As the structure of the model has been fine-tuned by training data, the model can be abused for accessing the data by the estimation in a reverse process called model inversion attack (MIA). Although, MIA has been applied to shallow neural network models of recognizers in literature and its threat in privacy violation has been approved, in the case of a deep learning (DL) model, its efficiency was under question. It was due to the complexity of a DL model structure, big number of DL model parameters, the huge size of training data, big number of registered users to a DL model and thereof big number of class labels. This research work first analyses the possibility of MIA on a deep learning model of a recognition system, namely a face recognizer. Second, despite the conventional MIA under the white box scenario of having partial access to the users' non-sensitive information in addition to the model structure, the MIA is implemented on a deep face recognition system by just having the model structure and parameters but not any user information. In this aspect, it is under a semi-white box scenario or in other words a gray-box scenario. The experimental results in targeting five registered users of a CNN-based face recognition system approve the possibility of regeneration of users' face images even for a deep model by MIA under a gray box scenario. Although, for some images the evaluation recognition score is low and the generated images are not easily recognizable, but for some other images the score is high and facial features of the targeted identities are observable. The objective and subjective evaluations demonstrate that privacy cyber-attack by MIA on a deep recognition system not only is feasible but also is a serious threat with increasing alert state in the future as there is considerable potential for integration more advanced ML techniques to MIA.

A Study on Research Trends in the Smart Farm Field using Topic Modeling and Semantic Network Analysis (토픽모델링과 언어네트워크분석을 활용한 스마트팜 연구 동향 분석)

  • Oh, Juyeon;Lee, Joonmyeong;Hong, Euiki
    • Journal of Digital Convergence
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    • v.20 no.2
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    • pp.203-215
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    • 2022
  • The study is to investigate research trends and knowledge structures in the Smart Farm field. To achieve the research purpose, keywords and the relationship among keywords were analyzed targeting 104 Korean academic journals related to the Smart Farm in KCI(Korea Citation Index), and topics were analyzed using the LDA Topic Modeling technique. As a result of the analysis, the main keywords in the Korean Smart Farm-related research field were 'environment', 'system', 'use', 'technology', 'cultivation', etc. The results of Degree, Betweenness, and Eigenvector Centrality were presented. There were 7 topics, such as 'Introduction analysis of Smart Farm', 'Eco-friendly Smart Farm and economic efficiency of Smart Farm', 'Smart Farm platform design', 'Smart Farm production optimization', 'Smart Farm ecosystem', 'Smart Farm system implementation', and 'Government policy for Smart Farm' in the results of Topic Modeling. This study will be expected to serve as basic data for policy development necessary to advance Korean Smart Farm research in the future by examining research trends related to Korean Smart Farm.

Folding Analysis of Paper Structure and Estimation of Optimal Collision Conditions for Reversal (종이구조물의 접기해석과 반전을 위한 최적충돌조건의 산정)

  • Gye-Hee Lee
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.36 no.4
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    • pp.213-220
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    • 2023
  • This paper presents a model simulating the folding process and collision dynamics of "ddakji", a traditional Korean game played using paper tiles (which are also referred to as ddakji). The model uses two A4 sheets as the base materials for ddakji. The folding process involves a series of boundary conditions that transform the wing part of the paper structure into a twisted configuration. A rigid plate boundary condition is also adopted for squeezing, establishing the shape and stress state of the game-ready ddakji through dynamic relaxation analysis. The gaming process analysis involves a forced displacement of the striking ddakji to a predetermined collision position. Collision analysis then follows at a given speed, with the objective of overturning the struck ddakji--a winning condition. A genetic algorithm-based optimization analysis identifies the optimal collision conditions that result in the overturning of the struck ddakji. For efficiency, the collision analysis is divided into two stages, with the second stage carried out only if the first stage predicts a possible overturn. The fitness function for the genetic algorithm during the first stage is the direction cosine of the struck ddakji, whereas in the second stage, it is the inverse of the speed, thus targeting the lowest overall collision speed. Consequently, this analysis provides optimal collision conditions for various compression thicknesses.

A Study on the Priority of Sustainability Areas and Indicators of Domestic Smart Ports (국내 스마트 항만의 지속가능성 영역과 지표의 우선순위에 관한 연구)

  • Lee, Jae-Hoon;Chang, Myung-Hee
    • Journal of Korea Port Economic Association
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    • v.38 no.4
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    • pp.65-85
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    • 2022
  • In this study, in order to derive the priority of indicators and sustainability areas of smart ports, which means ports in the digital era, previous studies and ESG, which have recently been indispensably introduced in all industries worldwide, were studied together. A hierarchical structure was established with upper evaluation items and 20 lower evaluation items in four areas (operational, environmental, social, and governance), and a relative evaluation method of weighting items among the AHP techniques was applied. The pairwise comparison questionnaire consisted of a 9-point scale proposed by Satty (1980). A survey was conducted targeting working-level workers who perform sustainability or ESG(Environmental, Social, Governance)-related work at four representative port authorities in Korea (Busan, Incheon, Ulsan, Yeosu Gwangyang). In order to increase the accuracy of the analysis results, AHP analysis was conducted on 17 questionnaires with a consistency ratio of 0.1 or less. As a result of the analysis, it was confirmed that among the four areas representing the sustainability of domestic smart ports, the operation area had the highest priority, followed by the environment area. In addition, looking at the overall priorities for the 20 detailed indicators, indicators such as operational efficiency, operational planning, energy management, and pollution measurement and management system were found to have high priority. On the other hand, it was confirmed that the social and the governance areas had relatively low importance compared to other areas.