• Journal of Information Processing Systems
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• 제17권1호
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• pp.14-27
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• 2021

Strong earthquakes have caused substantial losses in recent years, and earthquake risk prevention has aroused a significant amount of attention. Earthquake risk prevention products can help improve the self and mutual-rescue abilities of people, and can create convenient conditions for earthquake relief and reconstruction work. At present, it is difficult for earthquake risk prevention information systems to meet the information requirements of multiple scenarios, as they are highly specialized. Aiming at mitigating this shortcoming, this study investigates and analyzes four user roles (government users, public users, social force users, insurance market users), and summarizes their requirements for earthquake risk prevention products in the whole disaster chain, which comprises three scenarios (pre-quake preparedness, in-quake warning, and post-quake relief). A targeted recommendation rule base is then constructed based on the case analysis method. Considering the user's location, the earthquake magnitude, and the time that has passed since the earthquake occurred, a targeted recommendation model is built. Finally, an Android APP is implemented to realize the developed model. The APP can recommend multi-form earthquake risk prevention products to users according to their requirements under the three scenarios. Taking the 2019 Lushan earthquake as an example, the APP exhibits that the model can transfer real-time information to everyone to reduce the damage caused by an earthquake.

• 산업경영시스템학회지
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• 제37권1호
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• pp.68-78
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• 2014

Recently, companies are trying to gain a competitive advantage in the market to meet the voice of customer. For this purpose, QFD has been used as product development technology in many areas to include the customer' requirements. Also, Kano model has been used to understand the customer' requirements for an effective way. Therefore integration of Kano model and QFD can more efficiently reflect the customer' requirements when designing a new service. This paper proposes PI index by taking into account the current satisfaction position of our company and competitors while IR (Improvement Ratio) value was set uniformity. This study suggests a more accurate index to predict potential improvements and calculates the final importance or priority. Through case studies targeted at elevator maintenance companies, we can have a general idea how much to improve in the near future and estimate the final importance of customer requirements.

• Journal of Korean Neurosurgical Society
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• 제61권3호
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• pp.402-406
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• 2018

In contrast to many of the malignant tumors that occur in the central nervous system in adults, the management, responses to therapy, and future perspectives of children with malignant lesions of the brain hold considerable promise. Within the past 5 years, remarkable progress has been made with our understanding of the basic biology of the molecular genetics of several pediatric malignant brain tumors including medulloblastoma, ependymoma, atypical teratoid rhabdoid tumour, and high grade glioma/diffuse intrinsic pontine glioma. The recent literature in pediatric neuro-oncology was reviewed, and a summary of the major findings are presented. Meaningful sub-classifications of these tumors have arisen, placing children into discrete categories of disease with requirements for targeted therapy. While the mainstay of therapy these past 30 years has been a combination of central nervous system irradiation and conventional chemotherapy, now with the advent of high resolution genetic mapping, targeted therapies have emerged, and less emphasis is being placed on craniospinal irradiation. In this article, the present and future perspective of pediatric brain malignancy are reviewed in detail. The progress that has been made offers significant hope for the future for patients with these tumours.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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• pp.43-46
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• 2008

This study investigated if a requirement for screen gloss is needed in the TCO Requirements and was, therefore, targeted towards finding an acceptable reflex level. The results show that a glossy surface has an impact on the visual ergonomics, and for this reason we believe that a requirement is needed. Although, the results do not point to a single value that is better than another, so a selection for a requirement level has to be augmented with additional information. Such a discussion is given and 60 gloss units at 60 degrees ($GU_{60}$) was selected as the new requirement level for the TCO Requirements (TCO '03 and TCO '05).

• 대한임베디드공학회논문지
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• 제4권2호
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• pp.50-54
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• 2009

In this paper, we address a novel system-level power management technique which is specifically targeted for an ARM 11 MPCore system. Our proposed solution is a DPM technique which includes process monitoring, real time power analysis, and policy application to reduce the power consumption while meeting the performance requirement. One of the main contributions of this paper is that we systematically infer QoS requirements of processes without getting any additional information from the application. When multiple processes are running under various user level policies, priorities of the policy application are determined in such a way that the overall system performance is maintained while power consumption is effectively managed. Experimental results show that our DPM technique is very effective in reducing power consumption without violating system's QoS requirements.

• 한국건축시공학회지
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• 제18권4호
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• pp.329-335
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• 2018

본 연구의 목적은 기존 콘크리트 건물의 단면확대 내진보강 기술에서 필요한 고유동 고접착성의 보강 모르타르 배합의 개발이다. 보강 모르타르의 목표성능(플로우 220mm 이상, 압축강도 30MPa, 접착강도 1MPa 이상)을 위해 물-결합재비, 잔골재-결합재비, 폴리머-결합재비, 증점제 사용 및 초속경시멘트의 혼입 등을 변수로 단계적으로 배합실험을 수행하였다. 모르타르의 접착강도는 기존 콘크리트의 다양한 면 처리 상태에 따라 평가하였다. 실험결과로부터 단면증설용 보강 모르타르의 배합을 위해 폴리머-결합재비는 10%, 초속경시멘트의 치환율은 5%가 추천될 수 있었는데, 이 배합은 초기 플로우 220 mm, 높은 초기강도 발현, 압축강도 35 MPa 그리고 접착강도 1.2 MPa 이상의 성능을 보였다.

• 한국건축시공학회지
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• 제18권3호
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• pp.211-218
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• 2018

이 연구에서는 국내산 인공 경량골재를 사용한 콘크리트의 실험결과를 바탕으로 콘크리트 표준시방서의 관련내용에 대한 합리성 및 개정의 필요성을 평가하였다. 국내 표준시방서의 내용은 ACI 211.2, ACI 213, ACI 301, JASS 5 및 CEB-FIP 시방내용들과 비교하였다. 국내산 인공 경량 잔골재의 연속적 입도분포를 위해서는 최대직경 2.5mm 이하의 천연모래 혼입이 요구되었다. 경량골재 콘크리트의 재료분리 및 과도한 블리딩을 제어하기 위해서는 현재 시방서에서 제시된 최대 물-결합재비와 단위수량에 대한 수정이 요구되었다. 특히, 배합 목표성능인 초기 슬럼프, 28일 압축강도, 공기량 및 기건 단위용적중량에 대해 경량골재 콘크리트의 합리적인 배합설계 절차의 확립이 요구되었다. 결과적으로 콘크리트 표준시방서는 국내산 인공 경량골재의 특성을 고려하여 전반적이 개정이 요구되었다.

• BMB Reports
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• 제53권3호
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• pp.133-141
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• 2020

The epidermal growth factor receptor (EGFR), a member of the ErbB family (EGFR, ErbB2, ErbB3 and ErbB4), plays a crucial role in regulating various cellular responses such as proliferation, differentiation, and survival. As a result, aberrant activation of EGFR, mostly mediated through different classes of genomic alterations occurring within EGFR, is closely associated with the pathogenesis of numerous human cancers including lung adenocarcinoma, glioblastoma, and colorectal cancer. Thus, specific suppression of oncogenic activity of mutant EGFR with its targeted drugs has been routinely used in the clinic as a very effective anti-cancer strategy in treating a subset of tumors driven by such oncogenic EGFR mutants. However, the clinical efficacy of EGFR-targeted therapy does not last long due to several resistance mechanisms that emerge in the patients following the drug treatment. Thus, there is an urgent need for the development of novel therapeutic tactics specifically targeting mutant EGFR with the focus on the unique biological features of various mutant EGFR. Regarding this point, our review specifically emphasizes the recent findings about distinct requirements of receptor dimerization and autophosphorylation, which are critical steps for enzymatic activation of EGFR and signaling cascades, respectively, among wildtype and mutant EGFR and further discuss their clinical significance. In addition, the molecular mechanisms regulating EGFR dimerization and enzymatic activity by a key negative feedback inhibitor Mig6 as well as the clinical use for developing potential novel drugs targeting it are described in this review.

• 의학교육논단
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• 제17권2호
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• pp.69-77
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• 2015

Including the research in the medical curriculum is regarded as an important issue for medical education. Research experience at medical school has a positive impact on students and it motivates them to undertake further research in the future. The purpose of this study is to explore the factors to activate the research of medical school students. We investigated students' perception of the research curriculum in medical school. The survey for this study was conducted among 41 targeted medical school students from across the Republic of Korea. A total of 370 students from 26 medical schools responded. Benefits through research activities were to study about the areas of interest, as researchers had the opportunity to interact with professors and career. Students, furthermore, had difficulties in research due to data collection, the lack of research space and research funding. Requirements to activate the research were the time to participate in research activities, opening regular research courses, preparation of practical research program and motivation for such research. The medical school would need to improve the medical curriculum through the analysis of the environment and situation the school is facing based upon the in-depth analysis results of what the medical school is pursuing through the research activities, what the students want, what the potential difficulties are, and what the requirements are to improve the research curriculum.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제6권9호
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• pp.2302-2322
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• 2012

Wireless Body Area Networks (WBANs) are introduced as an enabling technology in tele-health for patient monitoring. Designing an efficient Medium Access Control (MAC) protocol is the main challenge in WBANs because of their various applications and strict requirements such as low level of energy consumption, low transmission delay, the wide range of data rates and prioritizing emergency data. In this paper, we propose a new MAC protocol to provide different requirements of WBANs targeted for medical applications. The proposed MAC provides an efficient emergency response mechanism by considering the correlation between medical signals. It also reduces the power consumption of nodes by minimizing contention access, reducing the probability of the collision and using an efficient synchronization algorithm. In addition, the proposed MAC protocol increases the data rate of the nodes by allocating the resources according to the condition of the network. Analytical and simulation results show that the proposed MAC protocol outperforms IEEE 802.15.4 MAC protocol in terms of power consumption level as well as the average response delay. Also, the comparison results of the proposed MAC with IEEE 802.15.6 MAC protocol show a tradeoff between average response delay and medical data rate.