• Korean Journal of Remote Sensing
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• v.34 no.2_1
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• pp.203-211
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• 2018

Dam discharge is carried out for the management of rivers and area around rivers due to rainy season or drought. Dam discharge should be based on an accurate understanding of the flow rate that can be accommodated in the river. Therefore, understanding the allowable storage capacity of river is an important factor in the management of the environment around the river. However, the methods using water level meters and images, which are currently used to determine the allowable flow rate of rivers, show limitations in terms of accuracy and efficiency. In order to solve these problems, this paper proposes a method to automatically calculate the allowable storage capacity of river based on the images taken by drone. In the first step, we create a 3D model of the river by using the drone images. This generation process consists of tiepoint extraction, image orientation, and image matching. In the second step, the allowable storage capacity is calculated by cross section analysis of the river using the generated river 3D model and the road and river layers in the target area. In this step, we determine the maximum water level of the river, extract the cross-sectional profile along the river, and use the 3D model to calculate the allowable storage capacity for the area. To prove our method, we used Bukhan river's data and as a result, the allowable storage volume was automatically extracted. It is expected that the proposed method will be useful for real - time management of rivers and surrounding areas and 3D models using drone.

• Applied Chemistry for Engineering
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• v.29 no.5
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• pp.503-509
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• 2018

In this study, we used the ultrasonic extraction process as a method to extract antioxidant substances from kudzu, and measured the content of iso-flavonoids puerarin, daidzein, daidzin contained in kudzu. The response surface methodology which is a statistical analysis method for optimizing the extraction amount of iso-flavonoids from the kudzu and the process condition for maximizing the yield was applied. It is the final objective of this study to effectively derive the condition of the process that matches the target response with a minimum number of experiments and analyze the effect of each process condition on the response. In the response surface methodology, the central composite design was applied and the optimum condition was analyzed, and the three independent variables were set to ultrasonic irradiation time, volume ratio of ethanol/ultrapure water, ultrasonic irradiation power. Using the response surface methodology, the optimum conditions with the maximum extraction yield and the content of iso-flavonoids were evaluated as ultrasonic irradiation time (24.75 min), ethanol / ultrapure water volume ratio (39.75 vol%), ultrasonic irradiation power (592.36 W). The overall satisfaction level appears as high as 0.8938, which is recognized at a significance level within 5%. As a result of analyzing the optimization process, it was confirmed that the ultrasonic irradiation time is the factor that most affects the responses.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.4
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• pp.661-667
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• 2010

Astragali Radix (AR) has been used in traditional medicinal herb, which is known to tonify the qi and blood. It has been asserted to be a tonic that can improve the function of the lungs, adrenal glands and the gastrointestinal tract, increase metabolism, promote healing and reduce fatigue. Also, Plantago asiatica (PA) has the anti-inflammatory, antiseptic, antitussive, cardiac, diuretic, expectorant, haemostatic effects, though it is considered to be less powerful than the seed. Recent research is showing that it is promising in lowering cholesterol and controlling diabetes. Obesity is characterized at the cellular level by an increase in the number and size of adipocytes differentiated from fibroblastic preadipocytes in adipose tissue. In the present study, we investigated the effects of 3 to 7 extracts of mixed medicinal herbs (water and ethanol extract of Astragali Radix; ARW and ARE, water and ethanol extract of Plantago asitica; PAW and PAE, and those mixed extracts; ARW+PAE, ARW+PAW and ARE+PAE) on adipogenesis and apoptosis in 3T3-L1 adipocytes by MTT assay, Oil-Red-O staining and TUNEL assay. And then, we determined total contents of phenolic compounds and flavonoid compounds in mixed herbal extracts. These result showed that herbal extracts (ARW, PAE and ARW+PAE) affected on adipogenesis and apoptosis in 3T3-L1 adipocytes among 3 to 7 extracts tested. Especially herbal mixed extracts (ARW+PAE) had the highest inhibition on differentiation of preadipocytes and lipoid accumulation of maturing adipocytes. And it did not affect cell viability of mature adipocytes, but herbal mixed extracts (ARW+PAE) increased apoptosis in mature adipocytes, as proved by highest concentration $200\;{\mu}g/m{\ell}$ using TUNEL assay. In addition, contents of total phenoilc compounds and flavonoids showed the highest level in ARE+PAE and PAE than ARW. These results suggest that this main target for adipocyte functions could be effective in improving the metabolic syndrome including obesity.

• The Korea Journal of Herbology
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• v.30 no.6
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• pp.7-15
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• 2015

Objectives : Rosa laevigata Michx. has been used for the treatment of renal disease in traditional Korean medicine. In this study, we investigated cytoprotective effect of R. laevigata water extract (RLE) against oxidative stress induced by arachidonic acid (AA) + iron.Methods : To evaluate the protective effects of RLE against AA + iron-induced oxidative stress in HepG2 cell, cell viability and changes on apoptosis-related proteins were assessed by MTT and immunoblot analyses. The effects of RLE on reduced glutathione level, production of reactive oxygen species and mitochondrial membrane potential were also monitored. Furthermore, to verify underlying molecular mechanism, NF-E2-related factor 2 (Nrf2) was examined by immunoblot analysis. Additionally, Nrf2 transactivation and its downstream target genes expression were also determined by reporter gene and realtime RT-PCR analyses.Results : RLE pretreatment (30-300 μg/ml) prevented cells from AA + iron-mediated cell death in a concentration dependent manner. In addition, 100 μg/ml RLE inhibited AA + iron-induced glutathione depletion, reactive oxygen species production and mitochondrial dysfunction. RLE accumulated nuclear Nrf2 and also transactivated Nrf2, which was evidenced by antioxidant response element- and glutathione S-transferase A2-driven luciferase activities and mRNA level of glutamate-cysteine ligase catalytic subunit, NAD(P)H:quinone oxidoreductase 1 and sestrin 2. Moreover, protective effect of RLE against AA + iron was abolished in Nrf2 knockout cells.Conclusions : These results indicate that RLE has the ability to protect hepatocyte against oxidative stress through Nrf2 activation.

• Journal of Korea Water Resources Association
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• v.45 no.8
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• pp.783-794
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• 2012

The analysis for unsteady flow is necessary to design the hydraulic structures affected by water level and discharge changes through time. The numerical model has been generally used for unsteady flow analysis, however it is difficult to acquire field data to calibrate and validate the numerical model. Even though it is possible to collect field data for some case, high cost and labor are required and sometimes it is considered that the confidence of measured data is very low. In this case, the experimental data for unsteady flow can be used to calibrate and validate the numerical model as an alternative. Therefore, the discharge-supply system which could generate various type of unsteady flow hydrograph was developed in this study. Also, the accuracy of the unsteady flow hydrograph generated by developed dischargesupply system in the experiment was evaluated by comparing with target hydrograph. Accuracy errors and Root Mean Square Error (RMSE) were analyzed for the rectangular-type hydrograph with sudden changes of flow, triangular-type hydrograph with short peak time, and bell-type flood hydrograph. As a result, the generating error of the discharge-supply system for the rectangular-type hydrograph was about 59% which was maximum error among various types. Also, it was represented that RMSE for the triangular-type hydrographs with single and double peaks were approximately corresponding to 10%. However, RMSE for the bell-type flood hydrograph was lower than 2%.

• Journal of the Korean Recycled Construction Resources Institute
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• v.3 no.1
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• pp.1-6
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• 2015

Recently, lots of researches on concrete with high volume mineral admixture such as ground granulated blast furnace slag (GGBFS) have been carried out to reduce $CO_2$. It is known that the precast concrete has an advantage of high strength at early age due to steam curing, even if concrete has high replacement level of mineral admixture. However it demands the investigation of compressive strength properties according to steam curing regimens. In this study, concretes with water-binder ratio of 32, 35% and water content of 135, 150, $165kg/m^3$ were produced to investigate compressive strength properties of high volume (60% by mass) GGBFS cement concrete according to steam curing regimens. Then steam curing was implemented with the maximum temperature of 50, $60^{\circ}C$ and steaming time of 5, 6, 7 hours. From the test results, it was found that steam curing was effective to raise early strength of high volume GGBFS cement concrete, but 28 day compressive strengths of steam cured specimens were lower than those of water cured specimens. Thus, a further study would be needed for the optimum steam curing regimens to satisfy target demolded strength and specified strength for the application of high volume GGBFS cement concrete to precast concrete members.

• Journal of the Korean Society of Marine Environment & Safety
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• v.20 no.2
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• pp.193-201
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• 2014

This study provided safe sailing speed and appropriate passing time to areas of known strong current water to prevent marine accident of the ships. To the interpretation of these data which target Myeongnyang waterway, AIS data of the ship was collected from $12^{th}$ July to $15^{th}$ July 2010 and site environment was investigated on $4^{th}$ September 2010. On the basis of the collected data, the 'Minimum Navigation Speed' and 'Optimum Navigation Speed' were calculated. It has also considered the 'Spare control force' or allowance and the 'Respond Rudder Angle' for each tidal current speed. Additionally, it suggested the safe passing time to strong current area by analyzing tidal level and tidal current speed. The conclusion of the research are as follows : (1) If the flow rate is greater than 4.4 kn, it is difficult for the model ship to control herself by her own steering power and to cope with tidal current pressure force and yaw moment caused by the tidal current.. (2) The minimum navigation speed should be over 2.3 times the tidal current and the optimum navigation speed should be over 4.0 times the tidal current. (3) When spring tide, the optimum passing time at Myeongnyang waterway is between 30 minutes to 1 hour before the time of high/low water, and at 5 hours after high/low water, passing of ships should be avoided because it is time when the flow rate is over 4 kn.

• Journal of Korea Water Resources Association
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• v.44 no.6
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• pp.497-510
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• 2011

A levee height is determined by adding a deterministic freeboard to a flood water level in Korea. In the USA, a levee height is determined by choosing a value conditionally among the freeboard criteria and the levels resulted from a probabilistic method. The probabilistic method adopts a conditional non-exceedance probability (CNP) which is the probability that the target stage will not be exceeded given a specific flood event. The purpose of the study is to compare Korean criterion for levee height estimation with that of the USA. Levee heights were determined according to the above two criteria at twenty-five cross sections in five streams. The results show that Korean criterion on average yields levee heights 20 cm higher than those calculated by the criterion of the USA. The larger the flood discharges become, the higher the levee height differences are usually. It is caused by the freeboard estimation criterion of Korea that the larger design flood is, the higher freeboard is given. Korean criterion, however, resulted in lower levee heights for smaller streams than those by the criterion of the USA. To sum it up, the Korean levee height criteria can result in overestimation or underestimation depending on flood discharge amount, being compared with the criteria of the USA. The Korean freeboard especially needs to be increased for smaller flood discharges.

• Journal of Korean Society on Water Environment
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• v.34 no.4
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• pp.375-381
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• 2018

The monitoring of phytoplankton biomass and community structure is essential as a first step to control the harmful cyanobacterial blooms in freshwater systems, such as seen in rivers and lakes, due to the process of eutrophication and climate change. In order to quantify the biomass of phytoplankton with a wide range in size and shape, the measurement of cell biovolume along with cell density is required for a comprehensive review on this issue. However, most routine monitoring programs preserve the gathered phytoplankton samples before analysis using chemical additives, because of the constraint of time and the number of samples. The purpose of this study was to investigate the cell biovolume change characteristics of six cyanobacterial species, which are common bloom-causing cyanobacteria in the Nakdong River, after the preservation with Lugol's iodine solution. All species showed a statistically significant difference after the addition of Lugol's iodine solution compared to the live cell biovolume, and the cell biovolume decreased to the level of 34.0 ~ 56.3 % at maximum in each species after the preservation. The nonlinear regression models for determining the shrinkage ratio by a preservation period were derived by using the cell biovolume measured until 180 days preservation of each target species, and the equation to convert the cell biovolume measured after preservation for a certain period to the cell biovolume of viable cell was derived using that formula. The conversion equation derived from this study can be used to estimate the actual cell biovolume in the natural environment at the time of sampling, by using the measured biovolume after the preservation in the phytoplankton monitoring. Moreover this is expected to contribute to the final interpretation of the water quality and aquatic ecosystem impacts due to the cyanobacterial blooms.

• Korean Journal of Medicinal Crop Science
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• v.26 no.2
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• pp.157-169
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• 2018

Background: Cassia tora L., an annual or perennial plant of the Fabaceae family, is traditional medicine with various biological activities, including anti-constipation and, anti-inflammation. Chemical compounds such as anthraquinone glycoside and naphthalene derivatives have been isolated from this plant. Cassia tora L. is a common contaminant of agricultural commodities, but is toxic to cattle and poultry. Methods and Results: To investigate the potential toxicity, Cassia tora L. aqueous extract (CO) was administered orally to rats for 26 weeks at 0 (control), 300, 1,500 and 3,000 mg/kg/day (n = 10 for male rats for each dose). The positive control comprised animals orally administered anthraquinone 100 mg/kg/day. There was no treatment-related mortality. An increase in the kidney weight was observed at 3,000 mg/kg/day of CO and anthraquinone 100 mg/kg/day. Macrophage infiltration in the colon was observed at CO 1,500 and 3,000 mg/kg/day and anthraquinone 100 mg/kg/day, but there were no significant toxicological changes in the incidence and severity of the finding. Conclusions: The oral no-observed-adverse-effect level (NOAEL) of CO was 3,000 mg/kg/day in male rats and no target organs were identified. In addition, 300 mg/kg was found to be the no-observed-effect level (NOEL) for systemic toxicity under the conditions of the study.