• Title/Summary/Keyword: t-stress term

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Study on the Efficacy of Paeonia Japonica, Cucurbita Moschata and Prunus Cerasus Complex Extract for Alleviating Stress Associated with Chronic Skin Conditions (만성 피부 질환으로 발생하는 스트레스 개선을 위한 호박, 작약, 타트체리 복합물의 효능 연구)

  • Su-Jin Park;Dong-Hee Kim;Ki-Sung Kwak;Hyun-Jeong Kim
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.459-471
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    • 2024
  • In modern society, where tension and stress are ubiquitous, individuals often experience psychological imbalances. These stressors not only affect mental well-being but also manifest physically, through the skin. Consequently, a new term psychodermatology combining psychiatry and dermatology, has emerged, garnerning attention and research focus. In this study, we aimed to develop materials improving chronic skin conditions caused by stress by utilizing a compound of Cucurbita moschata, Paeonia japonica, and Prunus cerasus known to alleviate skin disorders. We sought to develop and validate the efficacy of materials alleviating chronic skin conditions induced by stress in keratinocytes..Therefore, in this study we analyzed the effects of a complex extract using Cucurbita moschata, Paeonia japonica, and Prunus cerasus on HaCaT keratinocyte cells to understand how it influences them. The complex extract on HaCaT keratinocyte cells showed a concentration-dependent decrease in the expression levels of TNF-α, IL-1β, IL-6, MDC, and TARC at concentrations of 12.5, 25, 50 and 100 ㎍/mL. Particularly noteworthy was the efficacy observed in inhibiting IL-1β, with a reduction of over 40% at a concentration of 100 ㎍/mL. Additionally, the production levels of AQP-3, HA, and filaggrin exhibited a significant concentration-dependent increase. The protein expression of p-ERK, p-JNK, and p-p38, which were elevated by TNF-α/IFN-γ, was significantly decreased with the treatment of the complex extract. These findings suggest that the compound extract may be utilized as a material for treating and preventing skin conditions, potentially mitigating the adverse effects of the mutual relationship between skin disorders and stress.

Diabetes - Increased Risk for Cancers through Chromosomal Aberrations?

  • Anand, Sudhaa;Nath, Badari;Saraswathy, Radha
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4571-4573
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    • 2014
  • Diabetes, a comprehensive genetic disease, is principally due to the deregulation of glucose levels in the blood. In addition to contemporary epidemiological studies, systematic substantiation suggests that long-term diabetes leads to cancers due to a variety of reasons. In this study, blood samples were collected with informed consent from confirmed type I diabetic (T1DM, n=25) and type II Diabetic patients (T2DM, n=25) with equal numbers of controls. Further depending on the lifestyle habits they were subdivided into smokers/non-smokers and alcoholics/non-alcoholics. Chromosomal assays were performed for these cases and it was found that there was a significant increase in chromosomal aberration frequency in diabetic patient groups who are exposed to smoking and alcohol than that of normal diabetic groups (T1DM and T2DM). On the other hand, patient groups who were non-smoking and non-alcoholics also showed higher chromosomal aberrations when compared to that of controls. While the mechanisms for these increased chromosomal aberrations in diabetic groups are not clear, they may be due to increased oxidative stress leading to oxidative damage and resulting in genomic instability, which in turn may contribute to an increased risk for cancer.

The convergent influence of Perceived Stress and the Empowerment on Rehabilitation motive of Stroke patients (뇌졸중 환자가 지각한 스트레스와 임파워먼트가 재활동기에 미치는 융복합적 영향)

  • Kang, Hyo-Jeong;Kwon, Suhye;Youn, Soon-Chul
    • Journal of Digital Convergence
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    • v.14 no.1
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    • pp.291-303
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    • 2016
  • The purpose of this study has been done to identify the influencing factors on rehabilitation motive of stroke patients. A sample of 138 stroke patients in Long-term Care and rehabilitation hospitals completed questionnaires through face - to - face interviews. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and Stepwise multiple regression. Rehabilitation motive of stroke pacients was correlated with empowerment (r=.467, p<.001), but not with perceived stress(r=.-.186, p=.029). In a multiple regression, empowerment (${\beta}=.432$, p<.001) and primary care-giver (${\beta}=.175$, p=.023) were associated with rehabilitation motive. These factors attributed to 24% of the total variance in rehabilitation motive. Therefore, the study finding suggests that these significant factors should be considered when developing and implementing convergent care strategies for stroke patients in order to promote their rehabilitation motive.

Thallium-201 Perfusion Scan in Peripheral Arterial Disease (말초성 동맥 질환에 있어서 $^{201}T1$을 이용한 말초혈관 관류스캔의 유용성)

  • Nah, Jung-Il;Woo, In-Sook;Kim, Deog-Yoon;Koh, Eun-Mi;Kim, Jin-Woo;Kim, Young-Seol;Kim, Kwang-Won;Choi, Young-Kil
    • The Korean Journal of Nuclear Medicine
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    • v.25 no.2
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    • pp.192-199
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    • 1991
  • Peripheral arterial disease, because of it's significant and prolonged morbidity and related mortality is a major medical and surgical problem. Contrast angiogram remains the essential standard for the anatomic demonstration of disease. It does not, however, provide data suitable for quantification or any evaluation of the microcirculation. For these reasons, radionuclide studies are playing an increasingly important role by not only confirming the diagnosis and offering objective data on the physiologic significance of anatomic lesions, but by offering prognosis of healing and prediction of therapeutic results. In addition, radionuclide procedures offer means to safely and repeatedly monitor response to therapy and long term follow up. The object of this study was to evaluate the clinical availability of $^{201}T1$ perfusion scan in patients with peripheral arterial diseases. We performed $^{201}T1$ perfusion scans in patients with five Buerger' s disease (10 legs), six DM gangrenes (12 legs) and classified three perfusion pattern groups. Finally we compared treatment modalities among each groups and compaired T1-201 perfusion scan findings with angiographic findings in six patients with Buerger's disease. The results were as follows: 1) Seven legs showed increased perfusion in stress image and normal or increased perfusion in resting image (type 1). Six legs showed decreased perfusion in stress image and improved in resting image (type II). Of total 13 legs, only 1 leg needed to amputation. 2) Three legs showed decreased perfusion in stress and resting image (type III), and subsequently all cases were received surgical amputation. 3) In six Buerger's disease patients, there were disagreements in two patients (2 legs) between $^{201}T1$ scan and angiography, in which angiograms were normal but $^{201}T1$ scans showed 'type II' perfusion patterns.

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Depression Related Factors of Elderly Residence in Homeless Shelters (노숙인 쉼터 거주 노인의 우울 관련 요인)

  • Han, Young-Ran;Yoon, Hee-Sang;Choi, Ae-Sook
    • Journal of Korean Public Health Nursing
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    • v.25 no.2
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    • pp.289-301
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    • 2011
  • Purpose: This study was conducted to investigate the level of health behaviors, perceived health status, emotional and cognitive conditions and depression of the elderly residence in homeless shelters, and to identify related factors on their depression. Method: This was a descriptive study using a questionnaire. Geriatric Depression Scale (GDS-15) was used for examining depression, and other questionnaire were adopted and modified from the customized visiting health care service. Result: The 41 subjects displayed mild depression ($5.34{\pm}3.33$). The majority were non-smokers (73.2%) and non-drinkers (85%), and 81.1% of the subjects did light activities with 74.4 % performing regular exercise more than once per week. Perceived health status was above average in 70.7%, and feeling stress (70.7%), suicidal thoughts (12.2%) and abnomal KDSQ-C (29.3%) were shown in emotional and cognitive conditions. Depression had a significant relationship with regular exercise (t=3.61, p=.001), perceived health status (t=3.47, p=.041) and suicidal thoughts (t=2.85, p=.007). Conclusion: It is necessary to increase shelters for the elderly homeless and construct the system for examining not only their physical health but also their psychological problems, and to ensure long- term care recognizing their unique characteristics and needs, and their increasing number.

The Effects of Work Sense, Job Stress, Job Satisfaction on Turnover Intention of Caregivers in Long-Term Care Hospitals (요양병원 간병인의 직업의식, 직무스트레스, 직무만족도가 이직의도에 미치는 영향)

  • Hyeon-Suk Han;Wang-keun Yoo;Eun-Su Do
    • Korea Journal of Hospital Management
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    • v.28 no.4
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    • pp.23-32
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    • 2023
  • Purposes: Caregivers are placed in a poor working environment because there is no special legal basis or definition in the current medical system, and they have difficulty in supplying manpower due to frequent job change and retirement. Therefore, this study aimed to find out the effect on job consciousness, job stress, job satisfaction, and turnover intention of caregivers in nursing hospitals for the elderly. Methodology: In this study, a survey was conducted from May 2nd to 16th, 2022, targeting caregivers with more than 6 months of work experience working at 10 nursing hospitals in D City. Data were collected through convenience sampling, and a self-administered questionnaire method was used, in which subjects filled out a questionnaire. A total of 240 questionnaires were distributed, and 220 copies were considered for the final analysis after excluding non-response or inappropriate questionnaires for data use. Data analysis used t-test, ANOVA, Pearson's correlation coefficient, and multiple linear regression analysis, and the main results are as follows. Findings: Job stress and job satisfaction showed a significant correlation with the level of turnover intention, and were also found to be major determinants. On the other hand, among the occupational characteristics of the study subjects, employment type, job motivation, service period, number of patients, injury experience, and license status showed a significant difference from turnover intention. Conclusion: As a result of the above research, in order to prevent job turnover and retirement by improving job stress and job satisfaction of caregivers engaged in nursing hospitals, it is necessary not only to legalize caregivers, but also to secure an appropriate level of caregivers for nursing hospitals and improve specific treatment for caregivers. Ultimately, a policy alternative that can provide quality nursing service is required.

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Effects of Combat Related PTSD on Memory Function : in Vietnam Veterans (월남전 참전 재향군인들에서 외상 후 스트레스 장애가 기억기능에 미치는 영향)

  • Woo, Deuk-Ku;Kang, Hyun-Sook;Choi, Young-An
    • Korean Journal of Psychosomatic Medicine
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    • v.6 no.2
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    • pp.136-146
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    • 1998
  • Objectives : This study was performed to evaluate the effects of PTSD on memory function, to investigate the difference of memory function between PTSD and non-PTSD patients, and to identify major variables correlated to PTSD scale and Memory Assessment Scale. Methods: The authors used PTSD-scale(Mississippi scale and Combat Exposure Scale) for measuring PTSD severity. And, Beck Depression Inventory was also used. Memory assessment scale was assessed by well trained psychologist. Thirty one Vietnam veterans who had been hospitalized were collected consecutively. These patients were evaluated by psychiatrists with interview and measurement for fifteen months since March, 1997. The collected data were analyzed by SPSS and the stastistic methods used for analysis Chi-square, t-test, and Pearson's correlation. Results : 1) There were significant differences in short-term memory and verbal memory between PTSD and non-PTSD in Vietnam veterans. 2) Mississippi scale and Combat Exposure Scale were negatively correlated to short-term memory and verbal memory(Pearson's correlation). 3) Religion status was a significant variable between PTSD and non-PTSD in Vietnam veterans. 4) There is no significant difference in visual memory and total memory scale between PTSD and Non-PTSD in Vietnam veterans Conclusions : Neuropsychological changes were found in the posttraumatic stress disorder. There were significant differences in short-term memory and verbal memory between PTSD and non-PTSD in Vietnam veterans. Mississippi scale and Combat Exposure Scale were negatively correlated to short-term memory and verbal memory. We suggest that neuropsychological test might be used for an objective assessment of patients with the combat related PTSD and be considered helpful in the assessment of patients with the diagnosis. And we also suggest rehabilitation strategies would be used to compensate for memory deficits in PTSD patients.

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Construction Monitoring Methods of FCM Bridge Using Temperature Data (온도데이터를 활용한 현장타설 캔틸레버 교량의 시공 중 계측)

  • Kim, Hyun-Joong;Moon, Dae Joong;Nam, Soon Sung;Jeong, Ju Yong
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.29 no.3
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    • pp.219-227
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    • 2016
  • In this study, we have proposed a method of monitoring of bridges under construction in view of the long-term behavior of the prestress concrete bridge of which the Free Cantilever Method is applied. As a method to confirm the ability of the long-term behavior of the concrete box girder, temperature sensors and strain gauges were installed, and the measured data was used to calculate creep coefficient. Moreover, we have measured the stress of the concrete box girder during construction which was applied with creep coefficient and compared with the changes in temperature to analyze the vertical displacement along the segment. In conclusion, monitoring of the FCM bridge during construction in consideration of the long-term behavior can be analyzed efficiently by suing temperature and displacement data without the use of laser displacement meter or laser delfectometer.

Mixed Layer Variability in Northern Arabian Sea as Detected by an Argo Float

  • Bhaskar, T.V.S. Udaya;Swain, D.;Ravichandran, M.
    • Ocean Science Journal
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    • v.42 no.4
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    • pp.241-246
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    • 2007
  • Northern Arabian Sea (NAS) between $17^{\circ}N-20.5^{\circ}N$ and $59^{\circ}E-69^{\circ}E$ was observed by using Argo float daily data fur about 9 months, from April 2002 through December 2002. Results showed that during April - May mixed layer shoaled due to light winds, clear sky and intense solar insolation. Sea surface temperature (SST) rose by $2.3^{\circ}C$ and ocean gained an average of 99.8 $Wm^{-2}$. Mixed layer reached maximum depth of about 71 m during June - September owing to strong winds and cloudy skies. Ocean gained abnormally low $\sim18Wm^{-2}$ and SST dropped by $3.4^{\circ}C$. During the inter monsoon period, October, mixed layer shoaled and maintained a depth of 20 to 30 m. November - December was accompanied by moderate winds, dropping of SST by $1.5^{\circ}C$ and ocean lost an average of 52.5 $Wm^{-2}$. Mixed layer deepened gradually reaching a maximum of 62 m in December. Analysis of surface fluxes and winds suggested that winds and fluxes are the dominating factors causing deepening of mixed layer during summer and winter monsoon periods respectively. Relatively big]h correlation between MLD, net heat flux and wind speed revealed that short term variability of MLD coincided well with short term variability of surface forcing.

Characteristics of Wildbirds Habitat of Artificial Green Corridor in Gangseo-gu, Seoul (서울시 강서구 조성녹지축의 야생조류 서식처 특성 연구)

  • Choi, Jin-Woo;Lee, Kyong-Jae
    • Journal of Environmental Science International
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    • v.19 no.1
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    • pp.47-59
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    • 2010
  • This study was to examine the characteristics of wirdbirds habitat for improvement plan in green corridor. The target site, Gangseo-gu artificial green corridor was set up with the structure in which small scale of core green space with Goongsan and Yeomchang neighborhood parks in urbanized city was connected with the artificial green space with Gongamnaru, Hwanggeumnae neighborhood parks with 28~42.5 m in width. Wild birds six~eleven species; Dendrocopos spp, Paradoxornis webbiana, Parus major, Phasianus colchicus, etc. were observed in core green, but wild birds of two~five species: Columba livuia, Passer montanus, Pica pica, Hypsipetes amaurotis, etc. were observed in artificial green space. Thus wild birds of artificial and generalist species only moved in artificial green space. The artificial green space where vegetation structure was consisted of single-layer with poorness chose target species laying stress on generalist species and edge species of Parus major, P. palustris, Paradoxornis webbiana etc. for short-term and interior species of Dendrocopos major, Picus canus, etc. for long-term. The result suggested enhancement methods for target species's habitat in green corridor: to secure at least a corridor 30 meters in artificial corridor, to secure ecological pond, to offer the various shelterer and environment of prey-resources through the multi-layer structure.