• 대한임상전기생리학회지
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• 제2권3호
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• pp.1-12
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• 2004

Estrogens are critical to the functioning and maintenance of a diverse array of tissues and physiological systems in mammals. The actions of estrogen on such classical targets as the reproductive tract, gonads, mamary tissue, and hypothalamic/pituitary axis have been well characterized. A role in nonreproductive tissues, such as maintenance of bone mineral density and cardiovascular health in woman, as has been described. There were ne significant differences in the average of body weights, testis weights, among the experimental groups. The lumen of rate testis began to dilate from the day 8 and continued to the 59 post-treatment. The average diameter of dilate of rate testis in ICI 182,780 treated group increased 2.3-fold compared to the control group. Epithelical cell height in the rate testis of the treated mice decreased all the time periods, compared to the control.

• 음성과학
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• 제4권2호
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• pp.41-54
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• 1998

Speech signals are, depending on the characteristics of waveform, classified as voiced sound, unvoiced sound, and silence. Voiced sound, produced by an air flow generated by the vibration of the vocal cords, is quasi-periodic, while unvoiced sound, produced by a turbulent air flow passed through some constriction in the vocal tract, is noise-like. Silence represents the ambient noise signal during the absence of speech. The need for deciding whether a given segment of a speech waveform should be classified as voiced, unvoiced, or silence has arisen in many speech analysis systems. In this paper, a voiced/unvoiced/silence classification algorithm using spectral change in the wavelet transformed signal is proposed and then, experimental results are demonstrated with our discussions.

• 셀메드
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• 제9권2호
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• pp.3.1-3.5
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• 2019

Zingiber officinale is a spice which is having a strong historical medicinal background and used by different systems of medicine for various ailments. It is also used to maintain the characteristic sharpness and tangy essence of food and beverages and used in carbonated drinks, as a conserve in sugar syrup. Ginger considered as an incredible drug for inflammation, gastrointestinal problems, pain and sexual problems since centuries. There are many studies carried out in recent years, which proves that the active constituents of ginger shows a variety of pharmacological effects like antiemetic, hepatoprotective, anti hyperlipidemic and antibacterial. The most momentous among all the nutraceutical aspects of ginger are its positive control on gastrointestinal tract including digestive stimulant action, anticancer effect and anti-inflammatory effect.

• Tuberculosis and Respiratory Diseases
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• 제86권1호
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• pp.23-32
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• 2023

Everyone is aware that air and environmental pollutants are harmful to health. Among them, indoor air quality directly affects physical health, such as respiratory rather than outdoor air. However, studies that have examined the correlation between environmental and health information have been conducted with public data targeting large cohorts, and studies with real-time data analysis are insufficient. Therefore, this research explores the research with an indoor air quality monitoring (AQM) system based on developing environmental detection sensors and the internet of things to collect, monitor, and analyze environmental and health data from various data sources in real-time. It explores the usage of wearable devices for health monitoring systems. In addition, the availability of big data and artificial intelligence analysis and prediction has increased, investigating algorithmic studies for accurate prediction of hazardous environments and health impacts. Regarding health effects, techniques to prevent respiratory and related diseases were reviewed.

• 한국석유지질학회지
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• 제5권1_2호
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• pp.1-8
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• 1997

한국남동해 대륙붕에서 획득된 고해상탄성파탐사자료의 탄성파층서적 해석에 의하면 본 연구해역의 퇴적층은 서로 다른 4개의 퇴적층, 즉 하부로부터 퇴적층 D,퇴적층 C,퇴적층 B 및 퇴적층 A로 구성된다. 양산단층 연장부의 서쪽에 발달하는 퇴적층 D는 분지가 침강함에 따라 천해환경에서 퇴적된 것이나, 동쪽에 발달하는 것은 사면전면 충진형태로 형성되었다. 퇴적과 동시에 경동조구조운동이 일어나 육지쪽에 발달하는 사면전면 충진 퇴적층은 침식되어 인접한 사면에 퇴적되었다. 이 조구조운동은 울릉분지의 닫힘과 수반되어 일어난 것으로 보인다. 양산단층 연장부의 서쪽에 발달하는 퇴적층 C는 저해수면 하성퇴적물, 해침퇴적물, 그리고 고해수면 해성퇴적물이 겹쳐 쌓여서 형성된 것으로 추측된다. 동쪽에 발달하고 있는 퇴적층 C는 대륙붕단에서 퇴적된 것으로 해석되며, 이러한 작용으로 대륙붕단 외해로 전진하게 되었다. 퇴적층 C가 형성되는 동안에도 경동조구조운동은 계속되었으나, 퇴적층 D가 형성되는 동안에 있었던 것보다는 약하였다. 퇴적층 B가 형성되기 시작하면서 경동조구조운동은 멈추고, 선근원에서 점근원의 퇴적이 일어나기 시작하였다. 연구지역에 발달하는 본 퇴적층은 고해수면퇴적계, 저해수면퇴적계 그리고 해침퇴적계로 구분된다. 고해수면퇴적계는 욕지도주위에 부분적으로 보존되어 있으며, 저해수면퇴적계는 대한해곡에 비교적 잘 발달되어 있다. 해침퇴적계는 욕지도 및 거제도 남쪽앞 바다에 잘 보존되어 있다. 경동조구조운동이 멈추면서, 울릉분지의 닫힘작용에 의한 압축력은 주향단층들에 의해 해소되는 것으로 보인다./투스칼루사(Tuscaloosa) 사암층, 테일러(Taylor) 나바로(Navarro) 사암층과 오스틴(Austin) 백악 및 탄산염암층이 있다. 이 저류암층에 탄화수소를 공급했던 근원암층으로는 경사방향 하부의 셰일층이, 그리고 덮개암층은 경사방향 상부의 계일층이 그 역할을 담당했던 것으로 해석된다. 뗘악기 하부와 상부 퇴적층의 주요 트랩(trap)으로는 완만한 기둥형(pillow)으로부터 복잡한 다이아피어(diapir) 형태의 암염층 관련 배사구조와 하단 단층블록위에 놓여 있으며 롤오버(rollover) 배사구조를 갖는 성장단층이 있다. 투수 장애(permeability barrier), 상부 경사방향으로 첨멸하는 사암체(up-dip pinch-out sand body깥 침식부정합면(unconformity truncation)도. 걸프만 석유부존에 중요한 역할을 한 트랩들이다. 백악기의 주요한 저류암층들은 범세계 해수면곡선의 하강시기와 잘 일치하고 있는데 이는 백악기동안 형성된 걸프만의 퇴적층서가 범세계 해수면곡선을 전반적으로 잘 반영하고 있음을 의미한다. 즉 퇴적작용을 주로 지배하는 세 즌요 변수인 지구조적인 분지의 침강운동,퇴적물의 공급,해수면 변동오그÷중에서 해수면 변동요소가 이 시기동안 가장 중요한 역할을 했음을 의미한다.

• 한국지구과학회지
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• 제36권7호
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• pp.617-631
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• 2015

태백산 분지에 분포하는 탄산염 및 규질쇄설성 혼합 퇴적물로 구성된 세송층(late Middle Cambrian to Furongian)은 ${\delta}^{13}C$값이 1.14에서 2.81‰을 갖는 SPICE (Steptoean positive carbon excursion)를 15 m 두께의 층서구간에서 보여준다. SPICE는 Fenghuangella laevis대, Prochuangia mansuyi대 그리고 Chuangia대로 구성된 삼엽충 생물대에서 산출되며 이는 Paibian Stage의 하부에 해당된다. 세송층은 엽층리 이암, 단괴상 셰일, 엽층리 사암, 균질사암, 석회역암, 석회암-셰일 쌍을 포함한 6개의 암상으로 구성된다. 세송층은 폭풍파도기저면 아래의 외대륙붕에서 퇴적된 것으로 알려져 있다. 시기적으로 Paibian Stage에 속하는 SPICE는 세송층에서 고수위 퇴적계 다발, 대비 정합면과 해침퇴적계 다발에서 발견된다. SPICE의 최대 안정 탄소 동위원소 값은 상대적인 해수면 하강에 의해 형성된 대비 정합면과 일치한다. 세송층에서 SPICE의 산출은 SPICE가 화석의 산출이 결여된 지층의 전세계적 대비를 위해 사용될 수 있는 도구임을 암시한다.

• Journal of Veterinary Science
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• 제25권3호
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• pp.40.1-40.19
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• 2024

Importance: The creation of robust maternal-embryonic interactions and implantation models is important for comprehending the early stages of embryonic development and reproductive disorders. Traditional two-dimensional (2D) cell culture systems often fail to accurately mimic the highly complex in vivo conditions. The employment of three-dimensional (3D) organoids has emerged as a promising strategy to overcome these limitations in recent years. The advancements in the field of organoid technology have opened new avenues for studying the physiology and diseases affecting female reproductive tract. Observations: This review summarizes the current strategies and advancements in the field of 3D organoids to establish maternal-embryonic interaction and implantation models for use in research and personalized medicine in assisted reproductive technology. The concepts of endometrial organoids, menstrual blood flow organoids, placental trophoblast organoids, stem cell-derived blastoids, and in vitro-generated embryo models are discussed in detail. We show the incorportaion of organoid systems and microfluidic technology to enhance tissue performance and precise management of the cellular surroundings. Conclusions and Relevance: This review provides insights into the future direction of modeling maternal-embryonic interaction research and its combination with other powerful technologies to interfere with this dialogue either by promoting or hindering it for improving fertility or methods for contraception, respectively. The merging of organoid systems with microfluidics facilitates the creation of sophisticated and functional organoid models, enhancing insights into organ development, disease mechanisms, and personalized medical investigations.

• Animal cells and systems
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• 제3권2호
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• pp.193-197
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• 1999

A peroxidase-antiperoxidase method was used to detect the cells showing immunoreactivities to six hormone antibodies in the alimentary tracts of six frog species, Rana nigromaculata, R. rugosa, R. amurensis coreana, R. catesbeiana, Bombina orientalis, and Hyla arborea japonica, inhabiting Korea. The cells immunoreactive to gastrin and cholecystokinin-8 were observed in the pylorus of the stomachs and in the small intestines of all frog species examined. In contrast, these somatostatin-immunoreactive cells were identified in the esophagus and the whole gastrointestinal tracts, but were absent from the large intestines in R. rugosa, R. catesbeiana, B. orientalis and H. arborea japonica. The pancreatic polypeptide (PP)-immunoreactive cells represented their distribution limited to the small intestines of R. amurensis coreana and H. arborea japonica, and they were additionally identified in the pylorus of the stomachs in the other four species. Serotonin- and glucagon- Immunoreactive cells revealed different regional distributions in which the former were observed throughout the whole alimentary tracts in all frog species investigated, whereas the latter were not found in these regions at all. Endocrine cells were relatively abundant in the pyloric portion of the stomach compared to other organs. The present study showed that all endocrine cells except for PP had a similar distribution in the alimentary tracts of all frog species used.

• 대한세포병리학회지
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• 제11권2호
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• pp.65-73
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• 2000

Cytologlc evaluation of cerebrospinal fluid(CSF) is an effective mean for diagnosing many disorders involving the central nervous systems(CNS). One of the most important reasons for cytologic examination of CSF is to detect metastatic or primary neoplasms of the CNS. We did a retrospective study of 1,438 CSF specimens obtained between 1992 and 1996. A total of 1,205 adult and 233 pediatric CSF specimens from 947 patients were accessed at the Department of Pathology of Seoul National University Hospital and Children's Hospital, respectively. Among 1,438 CSF cytology specimens, 169 cases(11.8%, 77 patients) including 135 adult cases(59 patients) and 34 pediatric cases(18 patients) were positive for malignant cells. Diagnoses included 50 metastatic carcinomas(adult, 60; pediatric, 0); 46 malignant lymphomas(adult, 44; pediatric, 2); 21 leukemias(adult, 20; pediatric, 1); 4 retinoblastomas(adult, 0; pediatric 4); 2 rhabdomyosarcomas(adult, 0; pediatric, 2); 1 multiple myeloma(adult, 1; pediatric, 0), and 35 primary CNS neoplasms(adult, 10; pediatric, 25). The most commonly identified metastatic carcinomas in adults were adenocarcinoma. Their primary sites were the lung, gastrointestinal tract, and breast in order of frequency. The most common primary CNS neoplasm in children was medulloblastoma.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.1915-1919
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• 2004

In this paper, we propose a new discrete-time predictive current controller for a PMSM(Permanent Magnet Synchronous Motor). The main objectives of the current controllers are to ensure that the measured stator currents tract the command values accurately and to shorten the transient interval as much as possible, in order to obtain high-performance of ac drive system. The conventional predictive current controller is hard to implement in full digital current controller since a finite calculation time causes a delay between the current sensing time and the time that it takes to apply the voltage to motor. A new control strategy in this paper is seen the scheme that gets the fast adaptation of transient current change, the fast transient response tracking and is proposed simplified calculation. Moreover, the validity of the proposed method is demonstrated by numerical simulations and the simulation results will be verified the improvements of predictive controller and accuracy of the current controller.