• Title/Summary/Keyword: synthetic analysis

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Study on the immunogenicity of synthetic polypeptide vaccine derived from Theileria sergenti merozoite (Theileria sergenti merozoite의 합성 polypeptide 백신의 면역원성에 관한 연구)

  • Baek, Byeong-kirl;Seo, Chang-hee;Kim, Jin-ho;Kim, Byeong-su
    • Korean Journal of Veterinary Research
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    • v.35 no.1
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    • pp.87-94
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    • 1995
  • Western immunoblot analysis of antigen of T sergenti merozoite revealed that the immunodominant proteins of this organism were characterized as the 18KD, 29KD, 34KD, 45KD and 105KD in Korea. The 34KD and 45KD among those immunodominant proteins of the parasite were isolated and their amino acid sequences from the $NH_2$-terminus were determined and synthesized. They respective polypeptides were cationized to enhance their antigenicity, fortified with Freund's adjuvant and tested for immunogenicity in rabbits and cattle. The results obtained were as follows; 1. Theileria sergenti merozoite antigen was shown in 120KD, 100KD, 66KD, 45KD, 34KD and 30KD in western immunoblot using serum of rabbits immunized with 34KD synthetic polypeptide and 70KD, 58KD, 55KD and 45KD using bovine serum. In western immunoblot, 45KD, 34KD and 30KD were recognized by immunized rabbits, and 50KD and 45KD by cattle sera immunized with 45KD synthetic polypeptide, respectively. 2. The ELISA utilizing the synthetic polypeptides demonstrated significant antibody response to the respective peptides. After the 2nd booster injection, an OD of 0.760(preimmunization 0.132) in rabbits and an OD of 0.645(preimmunization 0.488) to 34KD synthetic polypeptide in cattle were observed. In animals immunized with 45KD synthetic polypeptide, after the 2nd booster injection, an OD of 0.640(preimmunization 0.144) in rabbit, and an OD of 0.776 (preimmunization 0.477) in cattle were measured. 3. After the 2nd booster the reciprocal IFA titer was 1:64 in rabbits and 1:512 in cattle immunized with the 34KD synthetic polypeptide. The IFA titre was observed as 1:512 in rabbit and 1:1,024 in cattle in immunized with the 45KD synthetic polypeptide.

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Analysis on the Combustion Characteristics of Low-Btu Synthetic Gases in Gas Engine (저발열량 합성가스의 가스엔진 내 연소 특성에 대한 해석)

  • Lee, Chan;Cho, Sang Mok
    • Clean Technology
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    • v.12 no.2
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    • pp.78-86
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    • 2006
  • Computational analyses are conducted on the combustion characteristics of the coal- and the biomass-derived synthetic gases with low-Btu heating value in gas engine. Using thermochemical analyses on the synthetic gases, combustion pressure, temperature, exhaust gas composition, NO emission and engine power are predicted and the predicted results are compared with small-scale pilot engine test results. In order to investigate the unsteady combustion phenomena in gas engine combustion chamber, CFD analyses are carried out on the coal and the biomass synthetic gases and their computed results are compared to provide the guidelines for the design modification and the tuning of the gas engine burning the synthetic gases as alternative fuels.

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Performance Analysis of Deep Learning-Based Detection/Classification for SAR Ground Targets with the Synthetic Dataset (합성 데이터를 이용한 SAR 지상표적의 딥러닝 탐지/분류 성능분석)

  • Ji-Hoon Park
    • Journal of the Korea Institute of Military Science and Technology
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    • v.27 no.2
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    • pp.147-155
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    • 2024
  • Based on the recently developed deep learning technology, many studies have been conducted on deep learning networks that simultaneously detect and classify targets of interest in synthetic aperture radar(SAR) images. Although numerous research results have been derived mainly with the open SAR ship datasets, there is a lack of work carried out on the deep learning network aimed at detecting and classifying SAR ground targets and trained with the synthetic dataset generated from electromagnetic scattering simulations. In this respect, this paper presents the deep learning network trained with the synthetic dataset and applies it to detecting and classifying real SAR ground targets. With experiment results, this paper also analyzes the network performance according to the composition ratio between the real measured data and the synthetic data involved in network training. Finally, the summary and limitations are discussed to give information on the future research direction.

Analysis of the contents of Practice and Synthetic Application area in Yanbian Textbooks (중국 연변 수학 교과서의 실천과 종합응용 영역에 나타난 학습내용 분석)

  • Lee, Daehyun
    • Journal of the Korean School Mathematics Society
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    • v.16 no.2
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    • pp.319-335
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    • 2013
  • Chinese mathematical curriculum is divided 4 areas(number and algebra, space and figure, statistics and probability, practice and synthetic application). The purpose of this paper is to analyze the contents of the practice and synthetic application in yanbian elementary textbook. For this, 12-textbook which was published in yeonbeon a publishing company is analyze by topic, mathematical process, area of content and mathematical activity. mathematical process The following results have been drawn from this study. First, contextual backgrounds of practice are restricted in classroom. The contents of synthetic application are limited in connection of mathematical areas. Mathematical problem solving is a main in mathematical process, whereas reasoning activity is a few. Mathematical experience activity is a main in mathematical process, whereas synthetic activity is a few. We can use the suggestions of this paper for development of textbook and the contents of mathematical process.

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NOx Formation Characteristics of the Coal-derived Synthetic Gas Containing $CH_4$ and $NH_3$ Components (메탄 및 암모니아를 포함하는 석탄 합성가스의 NOx 발생 특성)

  • Lee, Chan
    • Clean Technology
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    • v.14 no.2
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    • pp.117-122
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    • 2008
  • Theoretical analysis was conducted on the combustion and the NOx formation characteristics of the coal-derived synthetic gases with medium-BTU heating value. The synthetic gas was assumed to contain the major species of CO, $H_2,\;CO_2$, and $N_2$ and the minor species of $CH_4$ and $NH_3$. Through thermochemical analysis on the combustion of the synthetic gas, the flame temperature, major and minor species of exhaust gas, and thermal and fuel NOx emissions were computed. In addition, the effects of the $CH_4$ and the $NH_3$ components in syngas fuel on combustion and NOx emission were investigated. Based on the computed results on the synthetic gases, basic direction and guidelines were provided fur the low NOx design of gas turbine combustor.

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Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits

  • Joo, Myung-Jae;Cha, Jae-Kook;Lim, Hyun-Chang;Choi, Seong-Ho;Jung, Ui-Won
    • Journal of Periodontal and Implant Science
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    • v.47 no.2
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    • pp.86-95
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    • 2017
  • Purpose: The aim of this study was to determine the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2)-loaded synthetic bone substitute on implants that were simultaneously placed with sinus augmentation in rabbits. Methods: In this study, a circular access window was prepared in the maxillary sinus of rabbits (n=5) for a bone graft around an implant (${\varnothing}3{\times}6mm$) that was simultaneously placed anterior to the window. Synthetic bone substitute loaded with rhBMP-2 was placed on one side of the sinus to form the experimental group, and saline-soaked synthetic bone substitute was placed on the other side of the sinus to form the control group. After 4 weeks, sections were obtained for analysis by micro-computed tomography and histology. Results: Volumetric analysis showed that the median amount of newly formed bone was significantly greater in the BMP group than in the control group ($51.6mm^3$ and $46.6mm^3$, respectively; P=0.019). In the histometric analysis, the osseointegration height was also significantly greater in the BMP group at the medial surface of the implant (5.2 mm and 4.3 mm, respectively; P=0.037). Conclusions: In conclusion, an implant simultaneously placed with sinus augmentation using rhBMP-2-loaded synthetic bone substitute can be successfully osseointegrated, even when only a limited bone height is available during the early stage of healing.

A study on the image formation system variable and performance analysis for optimum design of high resolution SAR (고해상도 SAR 최적 설계를 위한 영상형성 시스템 변수 및 성능분석에 관한 연구)

  • Kwak, Jun-Young;Jeong, Dae-Gwon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.40 no.1
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    • pp.49-60
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    • 2012
  • Synthetic aperture radar (SAR) has been employed in various fields due to its capability to generate high resolution images regardless of weather and visibility. This paper presents a performance analysis on the image formation of high resolution SAR according to various slant range distance and synthetic aperture lengths using a range migration algorithm simulator. Although the visual performance on the SAR image is more accurate, a numeric analysis resulted in a comparable measurement. More specifically, raw data were generated for an ideal point target upon imaging geometries and design parameters such as slant range distance and synthetic aperture lengths. Finally, spatial resolution, peak to sidelobe ratio and integrated sidelobe ratio are drawn to provide SAR capabilities in the initial concept design, final in-flight calibration and validation stages.

Structural and thermal analysis of electrochemically Li intercalated synthetic graphite (전기 화학적으로 리튬이 층간 삽입된 인조흑연의 구조와 열적 특성 분석)

  • Oh, Won-Chun
    • Analytical Science and Technology
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    • v.14 no.3
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    • pp.197-202
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    • 2001
  • The characteristics of the electrochemically Li intercalated synthetic graphite were determined from the studies with XRD method, DSC and solid $^7Li-NMR$ spectrophotometric analysis. From the results of X-ray diffraction method, it was found that the compounds in the stage 1 structure were predominantly formed. The enthalpy and entropy changes of the compounds can be obtained from the differential scanning calorimetric analysis results. From these results, it was found that exothermic and endothermic reactions of lithium intercalated into synthetic graphite are related to thermal stability of lithium ion between carbon graphene layers. From the $^7Li-NMR$ data, scientific observation found that bands are shift toward higher frequencies with increasing lithium concentration because non-occupied electron shells of Li increased in charge carrier density. Line widths of the Li intercalated synthetic graphite compounds decreased slowly because of non-homogeneous local magnetic order and the random electron spin direction for substituted Li.

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Effect of Tannin Mordanting on Gromwell-dyed Silk Fabric (견직물의 자초 염색 시 합성탄닌의 매염 효과)

  • Park, Ah-Young;Song, Wha-Soon;Kim, In-Young
    • Textile Coloration and Finishing
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    • v.20 no.6
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    • pp.51-62
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    • 2008
  • The purpose of this study was to check color change depending on dyeing conditions when silk fabrics was dyed with gromwell and to investigate mordant effect when synthetic tannin was used as a mordant. First, when silk fabrics were dyed with gromwell, the change of color, brightness and chroma were examined by measuring K/S value, a, b value, L value and C value depending on dyeing condition. Second, color, brightness and chroma differences which appeared after mordanting with synthetic tannin were investigated and muti-functional mordanting effect was confirmed with dyeing fastness, antibiosis. As a result of color analysis of gromwell, it was proved that the main pigment of gromwell was shikonin. Color was red purple at pH 3 when silk fabrics were dyed with gromwell. But It became greenish and bluish as temperature rose and time passed by. And it grew reddish and yellowish as concentration level reached higher. The color became purple at pH 5 and purple blue at pH 7. Both at pH 5 and pH 7, it became greenish and yellowish, as temperature went up and time ran by. And it became reddish with concentration increasing. Brightness and chroma decreased with temperature and concentration increasing as well as time passing by. After mordanting with synthetic tannin, the color became less reddish at pH 3 and reddish-yellowish at pH 5 and pH 7. The brightness increased and the chroma decreased. At all pH, the color, the brightness and the chroma became similarly by synthetic tannin mordanting. Dyeing fastness of synthetic tannin mordanted fabric was higher than that of non-mordanted fabric. Especially, wet fastness at pH 3 improved from 1 grade before synthetic tannin mordanting to $3{\sim}4$ grade after tannin mordanting. Antibiosis was improved by gromwell dyeing and synthetic tannin mordanting.

Dosimetric Evaluation of Synthetic Computed Tomography Technique on Position Variation of Air Cavity in Magnetic Resonance-Guided Radiotherapy

  • Hyeongmin Jin;Hyun Joon An;Eui Kyu Chie;Jong Min Park;Jung-in Kim
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.142-149
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    • 2022
  • Purpose: This study seeks to compare the dosimetric parameters of the bulk electron density (ED) approach and synthetic computed tomography (CT) image in terms of position variation of the air cavity in magnetic resonance-guided radiotherapy (MRgRT) for patients with pancreatic cancer. Methods: This study included nine patients that previously received MRgRT and their simulation CT and magnetic resonance (MR) images were collected. Air cavities were manually delineated on simulation CT and MR images in the treatment planning system for each patient. The synthetic CT images were generated using the deep learning model trained in a prior study. Two more plans with identical beam parameters were recalculated with ED maps that were either manually overridden by the cavities or derived from the synthetic CT. Dose calculation accuracy was explored in terms of dose-volume histogram parameters and gamma analysis. Results: The D95% averages were 48.80 Gy, 48.50 Gy, and 48.23 Gy for the original, manually assigned, and synthetic CT-based dose distributions, respectively. The greatest deviation was observed for one patient, whose D95% to synthetic CT was 1.84 Gy higher than the original plan. Conclusions: The variation of the air cavity position in the gastrointestinal area affects the treatment dose calculation. Synthetic CT-based ED modification would be a significant option for shortening the time-consuming process and improving MRgRT treatment accuracy.