• Tuberculosis and Respiratory Diseases
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• 제81권2호
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• pp.116-122
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• 2018

Background: Chronic obstructive pulmonary disease (COPD) is a serious chronic condition with a global impact. Symptoms of COPD include progressive dyspnea, breathlessness, cough, and sputum production, which have a considerable impact on the lives of patients. In addition to the human cost of living with COPD and the resulting death, COPD entails a huge economic burden on the Chinese population, with patients spending up to one-third of the average family income on COPD management in some regions is clinically beneficial to adopt preventable measures via prudent COPD care utilization, monetary costs, and hospitalizations. Methods: Toward this end, this study compared the relative effectiveness of six indices in predicting patient healthcare utilization, cost of care, and patient health outcome. The six assessment systems evaluated included the three multidimensional Body mass index, Obstruction, Dyspnea, Exercise capacity index, Dyspnea, Obstruction, Smoking, Exacerbation (DOSE) index, and COPD Assessment Test index, or the unidimensional measures that best predict the future of patient healthcare utilization, cost of care, and patient health outcome among Chinese COPD patients. Results: Multiple linear regression models were created for each healthcare utilization, cost, and outcome including a single COPD index and the same group of demographic variables for each of the outcomes. Conclusion: We conclude that the DOSE index facilitates the prediction of patient healthcare utilization, disease expenditure, and negative clinical outcomes. Our study indicates that the DOSE index has a potential role beyond clinical predictions.

• 사상체질의학회지
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• 제20권2호
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• pp.43-52
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• 2008

1. Objectives This study aims to find out the factors that affect to healthy level according to Sasang Constitutions by comparing THI health state with Sasang Health Index. 2. Methods One hundred twenty one healthy students from Korean oriental medical colleges participated in this study. We used the Questionnaire for Sasang Constitution Classification II(QSCC II) and expert opinion to diagnose Sasang Constitution, and used Sasang Health Index and THI questionnaire to take health information about Sasang Constitution, from 121 people of Sasang Constitution Information Bank. 3. Results 1) The 'Good Sweat' in Taeumin health level was higher than others, especially in case of 'Refreshness after Sweat' and the 'Good Feces' also higher in case of 'Much Volume in Defecation' 'Regularity in Defecation' 'Refreshness after Evacuation'. 2) The 'Good Feces' in Soyangin health level was higher than others, especially in case of 'Thickness'. 3) The 'Good Digestion' in Soeumin health level was not significantly higher than others. 4) The better symptoms in 'Good Sweat', the better health in Taeumin. 4. Conclusions Sasang Constitution Health Level is significantly related with Sasang Health Index.

• 대한임상검사과학회지
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• 제38권3호
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• pp.212-217
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• 2006

Obstructive sleep apena syndrome (OSAS) is accompanied by the following symptoms: apnea caused by upper respiratory tract obstruction while sleeping, repetitive lowering of $SpO_2$, severely affected excessive daytime sleepiness (EDS), suffocation/frequent awakeness while sleeping, daytime lethargy, and lack of concentration. OSAS was investigated with sex, age, body weight, body mass index (BMI), neck circumference and snoring sound as clinical characteristics and the anticipating factors of OSAS were studied in relation with the apnea-hypopnea index (AHI). The subjects were 42 people (male 34/female 8) who visited the clinic due to snoring and had polysomnography evaluation. AHI was differenciated into normal (less than 0~5/hr), mild (5~15/hr), moderate (15~30/hr) and severe (more than 30/hr). As the apnea-hypopnea index (AHI) gets higher, the snoring sound was louder (p<0.01), neck circumference was thicker (p<0.05) and also there were relative correlations with body weight (p<0.01), body mass index (p<0.05), snoring sound (p<0.01) and neck circumference (p<0.01). Since the snoring sound and neck circumference explained 32.8% of the AHI distribution, if the patient was severely snoring or had a thick neck circumference due to obesity, the apnea-hypopnea index showed a predisposition to the obstructive sleep apnea syndrome.

• 한방안이비인후피부과학회지
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• 제27권1호
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• pp.17-36
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• 2014

Objectives : The purpose of this study is to investigate the efficacy of external preparation containing herbal extract(Sophorae Radix, Aurantii Immaturus Fructus, Schizonepetae Spica, Forsythia fructus and Portulacea Herba) on atopic dermatitis patients. Methods : A total of 33 patients who visited the Dept. of Ophthalmology, Otolaryngology & Dermatology of Korean Medicine of Korean Medical hospital of Daejeon university from February 2012 to February 2013 were engaged in this study. Patients who corresponded the requirements were enrolled in the study. This study shows symptom comparisons before and after the use of this product. Effectiveness was evaluated through SCORAD(SCORing Atopic Dermatitis) Index, and the quality of life scale was conducted through Skindex-29. Results : 1. Comparison of the general changes through SCORAD Index indicated that the experimental group showed more statistically significant declines than the placebo group after the two-week use. 2. Comparison of changes in intensity criteria(Erythema, Edema, Oozing, Excoriation) through SCORAD Index indicated that the experimental group showed more statistically significant declines than the placebo group after the two-week use. 3. Comparison of changes in subjective symptoms through SCORAD Index indicated that the experimental group showed no statistically remarkable changes. 4. Comparison of changes in the body parts(Upperlimb) through SCORAD Index indicated the experimental group showed statistically significant changes after the two-week use. 5. Comparison of the general changes in quality of life through Skindex-29 indicated that the total score from experimental group showed statistically significant changes after the four-week use. Conclusions: This study, evaluated through SCORAD Index, indicated that the treatment with the external preparation containing herbal extract has a statistically marginal significance of efficacy on atopic dermatitis patients in the short term.

• 대한예방한의학회지
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• 제23권1호
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• pp.61-72
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• 2019

Introduction : The aim of this study was to investigate menstrual pattern according to Mibyeong Index(MBI) and compare Mibyeong symptom score according to severity of menstrual pain. Mibyeong Index was designed to measure inconvenience and resilience of subject's complains including four physical symptoms(fatigue, pain, low sleep quality, indigestion) and mental distress including anxiety, anger, depression. Method : We used the clinical data of Korean medicine Date Center(KDC) for subjects who participated in the study of 'Clinical research for collecting of clinical cases based on the personal type of Mibyeng' conducted in Seoul, from June 26, 2015 to June 26, 2017. A total of 566 fertile women aged 30 to 50 who completed the questionnaires were included in this study. In this study, we used items of Mibyeong Index and the menstrual pattern by self-report questionnaires. The date were analyzed through Kruskal Wallis test, Pearson's chi-square test, and one-way ANOVA using SPSS statistics 19.0. Results : Mibyeong status was significantly associated with severity of menstrual pain(p<0.001), worst day of menstrual pain(p<0.05), and type of menstrual pain(low back pain, nausea, depression, and none (respectively, p<0.05)). In addition, The 7-subtype score (fatigue (p<0.001), pain(p<0.001), low sleep quality(p<0.001), indigestion(p<0.001), anxiety(p<0.05), anger(p<0.05) and depression(p<0.05)) of Mibyeong index and total score of Mibyeong Index (p<0.001) showed significant difference for severity of menstrual pain. Conclusion : This result indicates that a close relationship between Mibyeong status and severity of menstrual pain. Further studies are needed but, we hope that this results will be used as the basic data to improve mibyeong status through health care to alleviate dysmenorrhea.

• 수면정신생리
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• 제21권1호
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• pp.5-13
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• 2014

목 적: 노인성 우울증에서의 수면장애와 인지기능 저하의 동반은 흔히 나타나는 증상이다. 본 연구의 목적은 지역 사회에 살고 있는 노인 우울증 환자에서 나타나는 수면장애와 인지기능 저하의 양상을 파악하고 수면장애가 인지기능 저하와의 상관관계를 살펴보는 것이다. 방 법: 본 연구의 대상자들은 지역사회에 거주하고 치매 등의 인지기능 장애를 가지고 있지 않으며 수면 및 기분, 인지기능에 영향을 주는 정신과 약물을 복용하고 있지 않은 282명의 65세 이상 노인으로 하였다. 우울증의 평가를 위해 노인성 우울척도(Geriatric depression Scale, GDS)를 평가하였으며 GDS 점수에 따라 10점 미만을 대조군으로 하였고 10점 이상 17점 미만을 경도 우울증군, 17점 이상을 중증도 우울증군으로 분류하였다. 모든 대상자들에게 1회의 야간수면다원검사를 시행하여 객관적인 수면지표를 얻었고 피츠버그 수면의 질 지수(PSQI)를 평가하여 주관적인 수면의 질을 평가하였으며 CERAD-K 신경심리검사를 통하여 인지기능을 평가하였다. 결 과: 연구 대상자들의 평균연령, 성별, 내과적 질환 여부는 세 군 간에 유의한 차이가 없었으나 교육 연한은 대조군에 비해 중증도 우울증군에서 유의하게 낮은 결과를 보였다(p=0.015). 수면다원검사와 피츠버그 수면의 질 지수를 통하여 얻어진 수면지표들 중 REM수면시간, 무호흡-저호흡 지수, 산소 탈포화 지수, PSQI 점수는 세 군 간에 유의한 차이가 있었다(모든 p<0.05). 신경인지기능검사 결과에서는 단어목록재인검사, 스트룹 색깔 및 단어검사, 벤톤 시각 기억 검사-A, 길 만들기 검사-B에서 세 군 간에 통계적으로 유의한 차이가 나타났다(모든 p<0.05). 우울증군에서의 수면장애와 인지기능 저하 간에 상호 인과 관계를 알아보기 위한 Pearson 상관분석과 단계적 다중선형회귀분석 결과 수면장애와 인지기능 저하 간에 상호 관련성은 없는 것으로 나타났다. 결 론: 본 연구에서 노인성 우울증 환자에서 나타나는 수면무호흡증을 제외한 수면장애는 인지기능 저하에 직접적인 영향을 미치지는 않는 것으로 나타났다. 이러한 결과는 노령화에 따른 수면장애 및 수면구조의 변화와 연령, 교육 수준 등의 영향으로 인한 것으로 보인다. 그러나 노인 인구에서의 수면장애의 높은 유병률과 잠재적으로 인지기능에 미칠 수 있는 부정적인 영향력을 고려할 때 후속 연구를 통한 노인성 우울증 환자에서의 수면장애와 인지기능 저하의 상호 관련성에 대한 논의가 요구된다.

• Journal of Hospice and Palliative Care
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• 제12권4호
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• pp.177-193
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• 2009

완화의학에서 환자의 평가는 치료의 의사결정과 그 결과에 이르기까지 중요한 역할을 한다. 평가도구의 사용 목적은 이를 환자 진료에 반영하여 개개인 환자와 가족들에 대한 돌봄의 질을 높이는 데 있다. 환자의 기능 상태와 통증 및 비 통증 증상을 평가하는 다양한 단일 영역 및 다차원 평가 척도들이 사용 가능하며, 삶의 질을 측정하는 다양한 도구들이 존재한다. 삶의 질이나 증상 측정에서 우월하다고 추천되는 단일 도구는 없는 실정이다. 도구마다 측정하는 시간의 틀이 다르고, 특성이 다르므로 사용 목적과 상황에 따라 적절한 도구를 선택하여야 한다. 여명 예측을 위해서는 예후 지수의 병용이 권고되는 추세이고, 웹을 기반으로 하는 예측 프로그램들도 등장하였다. 예후지수로는 최근 우리나라에서 다기관 연구를 통해 개발한 객관적 예후지수가 임상적인 여명 예측을 포함하지 않으면서 새로운 객관적인 예후 요인을 반영하여, 누구나 쉽게 사용이 가능하다. 완화의학 입문자의 경우 상대적으로 사용이 용이한 도구가 좋다. 따라서 기능의 평가에는 Eastern Cooperative Oncology Group 기능지수를 사용하고, 통증에서는 10점만점의 숫자 통증 등급(Numeric Rating Scale) 도구를 활용하면서 초기 통증 평가로는 간이 통증 조사지를 추천한다. 여러 가지 증상을 한꺼번에 측정하기 위해서는 숫자 등급으로 직접 물어보거나 혹은 M.D. Anderson 증상조사지(the Korean version of MD Anderson Symptom Inventory) 설문지를 사용하기 바란다. 삶의 질을 평가하는데에는 European Organization Research and Treatment Quality of Life Questionnaire Core 15 for Palliative Care, 예후 지수로는 객관적 예후 지수(Objective Prognostic Score)를 사용하기를 권한다. 향후 완화의학에서 평가도구의 발전방향은 국제 공동 연구의 활성화와 디지털 기기를 통한환자 보고의 전산화이고, 머지않은 앞날에 우리나라에도 이러한 경향이 도입될 것이다.

• 생물정신의학
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• 제20권2호
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• pp.54-60
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• 2013

Objectives The purpose of this study is to find the influential clinical and physical characteristics which affect apnea-hypopnea index (AHI) in suspected obstructive sleep apnea (OSA) patients. Methods We evaluated the comprehensive factors including sleep related symptoms, clinical scales, medical history, substance use, and anthropometric data of the 119 participants who complained of the symptoms of OSA. All the participants underwent attended-full night laboratory polysomnography. The correlation and multiple regression analysis were conducted to find the influential and predictive factors of AHI. Results A multiple linear regression model 1 showed that higher AHI was associated with higher body mass index (BMI)(p < 0.001) and higher frequency of observed apnea (p = 0.002). In multiple linear regression model 2, AHI was associated with higher BMI (p < 0.001) and loudness of snoring (p = 0.018). Conclusions The present preliminary results suggest that BMI and observed apnea are most influential factors that affect AHI in suspected OSA patients. In the future study we will design the prediction formula for the OSA and AHI, which is useful in the clinical medical field.

• 대한한방내과학회지
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• 제34권4호
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• pp.428-437
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• 2013

Objectives : The aim of this study was to examine if there is a significant correlation between the changes of Fire- and Heat- related symptoms and motor function recovery in acute cerebral infarction patients. Methods : We studied inpatients within a month after the onset of cerebral infarction who were admitted at Kyunghee University Medical Center from May 2011 to January 2013. We executed correlation analysis between Fire-heat pattern score and motricity index score at visit 1 and visit 2, and checked if there was a significant correlation between the changes of Fire-heat pattern score and changes of motricity index score. Also, we compared the changes of both scores in patients taking Fire-heat and non Fire-heat pattern prescriptions. Results : There was a significant correlation between the Fire-heat pattern score and Motricity index score at visit 1 and visit 2, and changes of Fire-heat pattern score showed significant correlation with changes of motricity index score. Patients taking Fire-heat pattern prescriptions showed significant change in Fire-heat pattern score after herb-medication treatment while patients taking non-Fire-heat prescriptions showed insignificant change in Fire-heat pattern score. Conclusions : This study provides evidence that taking a Fire-heat pattern prescription could be considered as a first line herb-medication treatment in acute cerebral infarction patients.

• 한국가정과교육학회지
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• 제34권3호
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• pp.85-99
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• 2022

본 연구는 한국 폐경 후 여성을 대상으로 우울증과 식이성 염증지수 간의 관련성을 살펴보기 위하여 국민건강영양조사 2016~2020년의 자료를 이용하여 식이성 염증지수 수준에 따른 식행동, 항염증과 염증유발 항목의 영양소 및 식품 섭취량, 식이성 염증지수와 우울증과의 관계에 관하여 비교 분석하였다. 본 연구결과 염증성 식이군은 항염증 식이군에 비해 혼자서 거주하는 비율이 높고, 교육수준과 소득수준이 낮았다. 건강행태 요인으로 염증성 식이군은 흡연율이 높고 신체활동율과 삶의 질이 낮으며, 식행동 요인으로는 아침, 점심, 저녁 식사 결식률과 가족 동반 아침식사 비율, 영양표시 인지율이 낮았다. 식이성 염증지수 점수가 높을수록 우울증상 선별도구인 PHQ-9 점수와 우울증 교차비는 증가하였다. 식이성 염증지수의 항염증 항목 중 MUFA, PUFA, n-3계 지방산, n-6계 지방산 항목은 식이성 염증지수 점수가 증가할수록 우울증 유병위험도가 증가하였다. 따라서 본 연구는 폐경 후 여성의 우울증 관리를 위한 바람직한 식생활과 항염증성 식사 섭취 지침에 기초자료를 제시할 수 있을 것으로 기대한다.