• Title/Summary/Keyword: symptom-free period

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A Case Report on the Effect of Jeongjeongamiijin-tang-gamibang on Halitosis Patients (정전가미이진탕가미방으로 치료한 구취환자 증례보고)

  • Kang, Kiwon;An, Jihye;Jang, Younyong;Park, Jisan;Jo, Youngju;Jung, Seungwon;Kim, Jeongkyun
    • Herbal Formula Science
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    • v.28 no.4
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    • pp.443-450
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    • 2020
  • Objectives : The aim of this study is to evaluate the long-term effect of Jeongjeongamiijin-tang-gamibang by measuring the symptom-free-period after treatment through sensory and subjective evaluation. Methods : We administered Jeongjeongamiijin-tang-gamibang to 10 patients diagnosed with stomach heat pattern. The asymptomatic period was measured from the end of treatment by sensory and subjective evaluation. Results : The total dose of medication administered to the patients was dose of 3 to 7 months and the mean was 4.1 months. Symptom-free period from the end of treatment was 24.5 to 69.4months, and the mean of treatment was 46.97 months. Conclusions : Jeongjeongamiijintanggamibang is effective for the treatment of halitosis and its effect is sustained for a long time.

Pattern of Cerebral Glucose Metabolism on F-18 FDG Brain PET during Vomiting and Symptom Free Periods in Cyclic Vomiting Syndrome (주기성 구토 증후군 환아에서 보인 F-18 FDG PET에서의 뇌 포도당 대사 소견)

  • Kim, Yu-Kyeong;Lee, Dong-Soo;Kang, Eun-Joo;Seo, Jeong-Kee;Yeo, Jeong-Seok;Chung, June-Key;Lee, Myung-Chul
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.3
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    • pp.198-204
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    • 2001
  • Cyclic Vomiting Syndrome (CVS) is characterized by recurrent, periodic, self-limiting vomiting. However, its pathogenesis is not yet established. We investigated the changes of the cerebral glucose metabolism using F-18 FDG during the vomiting attack and symptom free period in two children with CVS. FDG PET study showed the markedly increased metabolism in both temporal lobes and also in the medulla and cerebellum during the vomiting period. Also, FDG PET showed the decreased metabolism un the parieto-occipital and occipital areas during the vomiting period. The area with decreased metabolism seemed to be related with the region showing abnormalities in EEG and perfusion SPECT studies. We expect that what we observed would be a helpful finding in clarifying the pathogenesis of the CVS.

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Percutaneous C2 Ganglionotomy in the Management of Occipital Neuralgia -A case report- (후두신경통 환자에서 시행한 경피적 제2경추신경절 절제술 -증례 보고-)

  • Lim, So-Young;Kim, Su-Gwan;Shin, Keun-Man;Hong, Soon-Yong;Choi, Young-Ryong
    • The Korean Journal of Pain
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    • v.9 no.1
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    • pp.200-205
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    • 1996
  • Radiofrequency thermocoagulation(RF) techniques are safe and effective methods as compared to neurodestructive procedure. Other advantages are: ability to perform RF lesions under local or sedative anesthesia, rapid recovery period, low incidence of morbidity and mortality, ability to repeat RF lesions, and leaves no significant scarring. We performed C2 ganglionotomy by RF lesion generator on a patient, suffering post-traumatic occipital neuralgia, as the patient did not respond to conservative therapies such as: trigger point injection, TENS, cryotherapy and stretch, occipital nerve block, C2 ganglion block. Prognostic nerve block was performed usng local anesthetics. Excellent effect was conformed before C2 ganglionotomy. This procedure was performed under fluoroscopy. Type RCK-2A Rosomoff Cordotomy kit was used to stabilize the head and neck. Postoperatively, the patient was free of occipital pain and head motions no longer triggered pain. To date, the patient remains symptom free except for some cervical discomfort.

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Intraneural Ganglion of the Digital Nerve of the Hand - A Case Report - (수부에서 수지 신경의 신경내 결절종 - 증례 보고 -)

  • Park, Do-Young;Lee, Yu-Sang;Han, Kyeong-Jin
    • Archives of Reconstructive Microsurgery
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    • v.20 no.1
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    • pp.78-81
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    • 2011
  • Intraneural ganglia in the upper extremity are rare, and the involvement of the digital nerve of hand has not been reported. The following case report demonstrates a 57-year-old woman with a symptomatic nodular mass on the thenar area of the left hand. Magnetic resonance images showed a lobulated, homogeneous mass of high signal intensity on T2-weighted images and low signal intensity with peripheral enhancement on T1-weighted images. Excisional biopsy and histopathologic examination revealed an intraneural ganglion of the digital nerve of the thumb. Her symptom disappeared immediately after the surgery, and has remained free of abnormal sensation and parestheia for the 3-year follow-up period.

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Cross-sectional Study on Health Status and Symptom Recognition of Adolescents by Grade (학년에 따른 청소년의 건강상태와 증상인식에 대한 단면조사 연구)

  • Shin, Seon Mi;Park, Jeong Su;Go, Ho Yeon;Kim, Dong Su;Sung, Hyun Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.32 no.6
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    • pp.403-410
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    • 2018
  • Lifestyle of adolescents cause a lot of health effects in the future. Therefore, in Korea, school health law was enacted and relevant business such as school education program is being carried out. This study was conducted to recognize symptom according to grade. A survey of youth health status was conducted at 19 middle and high schools in Seongnam city from May 2015 to December 2015. The survey made up of 14 questions which was about the health status satisfaction on the adolescent was conducted to investigate frequency by year and the respective health status of 6 grades. A total of 9,584 students responded to the survey, 58.22% answered that they were not free of constipation. 25.69% of respondents had no symptoms of headache, consequently over 70% of respondents had headache. 57.06% of respondents had no symptoms of low back pain and 34.7% had no symptoms of neck & shoulder pain, therefore over 50% of respondents had muscular skeletal symptoms. In menstrual history, only 17.95% of respondents said their period was regular and painless. In respiratory history, except cold, no nasal drop & obstruction has appeared in the group of 54.02%. And 62.97% of respondents had persistent cough usually with cold and 23.41% had cough with cold breeze even if not catch cold. In the third grade of high school students, there were many complaints of pain in various parts such as headache, back pain and shoulder pain, neck pain and menstrual pain, and there was a high rate of complaints of digestive system symptom and defecation symptom. More than half of respondent had constipation discomfort, headache and musculo-skeletal symptoms, menstrual problems and cough. In the third grade of high school students, the rate of complaints of pain complaints, digestive system symptoms, and bowel symptoms was high. Therefore, there is a need for measures and management for continuous health care and health promotion in accordance with students' symptoms and age at each grade level.

Congenital Esophago-Bronchial Fistula without Esophageal Atresia (Report of 6 Cases) (성인의 선천성 식도.기관지루 6례 보고)

  • Hur, Y.; Kang, K.H.;Moon, K.H.;Kim, B.Y.;Lee, J.H.;Yu, H.S.;Sohn, J.H.;Park, H.S.
    • Journal of Chest Surgery
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    • v.21 no.3
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    • pp.594-600
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    • 1988
  • We had been experienced 6 cases of congenital esophagobronchial fistula which underwent surgical intervention in all cases. Of the 6 patients, 5 patients were male, one patient was female. The mean age of patients was 37.8 years old and clinical symptom free period was 27.1 years. According to Braimbridge`s classification, they were belonged to the type II[3 cases], type III[2 cases], <% type I[1 case]. Pre-operative diagnosis was available in 4 cases and the 2 cases could be diagnosed at operation field. The fistulectomy were performed in all cases, concomitant segmental resection[1 case], lobectomy[1 case], bi-lobectomy[1 case], and pneumonectomy[3 cases] were combined.

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Clinical Experience of Management of Lower Leg Pain due to Chloroma of Lumbosacral Bone in Chronic Myelogenous Leukemia (만성골수성 백혈병 환자에서 발생한 요천추부 Chloroma로 인한 좌하지통증의 치료경험 1예 보고)

  • Sung, Choon-Ho;Chung, Woon-Hyok
    • The Korean Journal of Pain
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    • v.2 no.1
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    • pp.61-65
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    • 1989
  • Chloroma is a localized myeloblastic tumor which may develop during the course of myelogenous leukemia or as a presenting sign of the disease. A 47-year-old female diagnosed as chronic myelogenous leukemia in her hematologic remission period complained of left lower leg pain. The lumbar-spine series showed multiple osteolytic changes in the left lateral border of the lumbar spine. An inhomogenous soft tissue mass involving left lateral aspects of lumbar vertebrae was identified by CT-scanning. At the first pain attack, lumbar epidural steroid and local anesthetic injection could abolish her pain and the patient could go a few days without pain. The following radiation therapy could also improve the symptom and retain the pain free interval. One month later, a second pain attack occurred and lumbar and caudal epidural steroid and local anesthetic injections could result only in an incidental relief of pain. Radiation and chemotherapy were started but failed to relieve pain. A neurolytic block was considered but the patient's general condition was aggravated and even verbal communication with her became impossible.

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Studies on the Potato Virus X and Potato Leaf Roll Virus for Disease-free Seed Potato Production (무병종서 생산을 위한 감자X바이러스 및 엽권바이러스에 관한 연구)

  • Jhung-Il Choi
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.7 no.1
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    • pp.31-63
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    • 1969
  • A series of experiment was carried out to study on the production of disease-free seed potatoes at the Alpine Experiment Station from 1960 to 1968, which initiated a study of comparison on degeneration of plain warm region and high altitude products and the effect of latent potato virus X (PVX) and potato leaf roll virus(PLRV) on degeneration. Particular observations were made on some aspect of the nature of potato virus disease and its control such as concentrations of PVX, range of host plants, physical properties such as concentrations of PYX, range of host plants, physical properties and carrying effect of insects, by investigating 9 different areas of the main potato producing regions (Kimhae, Taegu, Choongju, Taejoen, Suwon, Kwangju, Chonju, Cheju and Chinju). Highly purified anti-serum was separated and tested for control of the virus disease and also various method of prevention and control of PLRV were observed, using cultivation of sprouted seed tubers, early harvesting method, and systemic chemicals. The results obtained are summarized as follows; 1. Potato yield in the plain region decreased by 32.8~66.3% in the first year cultivation of seed potatoes from colder region, and the rate of virus infection was 92.9 to 95.4%. 2. Plants of three families including, 20 species were susceptible to the PVX, and among the plants Salvia officinalis of a habits only was the carrier while the symptom of Digitalis purpurea of Screphulariaceae was masked. Necrosis and ring spot was occurred in most pJants of the Solanaceae and ring spot symptom also was observed in Nicotiana tabacum L. var. White Burley and in N. glutinosa. 3. The 8$C_2$ strain of virus had the following physical properties; thermal inactivation point, 68-$72^{\circ}C$ : dilution inactivation point, above 1, 000, 000 dilution: ageing in vitro, 240-360 days: and ageing in dry plant tissue, 30 days. 4. Myzus persicae and Oxya spp. did not transmit the 8$C_2$ strain of potato virus. 5. Virus was purified through the ammonium sulphate isolating method, and higher titer value, 1/2048 was obtained through anti-serum test. 6. Inhibition Chenopodiacae on the virus infection of potato was remarkable, and inhibition of local lesion host also was observed. 7, By earlier planting of sprouted seed tubers, growth period could be prolonged by 10 to 12 days. 8. Earlier harvest decreased much the rate of virus infection of seed potatoes. 9. According to the results of aphid control trial using systemic soil insecticides at Kangnung and Taekwanlyung, PSP 204, Disyston and Thimet was effective to aphid control. In particular, control effect of twice treatments of PSP 204 was great. 10. Treatmental effect of those chemicals lasted about 60-70 days. However, single foliar application of emulsified chemicals was not effective to potato virus control. 11. The effect of PSP 204, Disyston, and Thimet on the control of potato leaf roll virus was great, particularly in the case of two treatments of PSP 204, at Kangnung as well as at Taekwanlyung. Higher negative correlationship between the control effect of potato leaf roll virus and potato yield was observed showing the value r=-0.85 at Kangnung, and r=-0.87 at Taekwanlyung. 12. Differences in the control effects among PSP 204, Disyston, and Thimet was not noticed.

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Brain Metastasis after a Gastrectomy for Gastric Cancer (위암의 근치적 절제 후 발생한 뇌 전이)

  • Kim, Yong-Il;Lee, Jun-Ho;Yun, Seong-Hyeon;Noh, Sung-Hoon;Min, Jin-Sik
    • Journal of Gastric Cancer
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    • v.1 no.2
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    • pp.113-118
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    • 2001
  • Purpose: The common features of brain metastases from gastric cancer are unknown because brain metastasis is an uncommon pattern of metastasis. The purpose of this study was to investigate the clinical features of and the prognosis for patients with brain metastases after a curative resection for gastric cancer. Materials and Methods: Twenty-one (21) cases of patients with brain metastases of gastric cancer, who had been treated at the Department of Surgery, Yonsei University College of Medicine, were assessed retrospectively. Results: The mean age was $55.8\pm9.6$ years (range: $34\~70$ years), and the male-to-female ratio was 2.5 : .1. The most common neurologic symptom was headache ($38.5\%$), and no patient was free from the neurologic symptoms. The incidence of parenchymal metastasis (PM: $76.2\%$) was higher than that of leptomeningeal metastasis (LM: $19.0\%$). Patients with gastric cancer and brain metastasis showed high rates of blood and lymphatic vessel invasion (lymphatic vessel invasion: $85.7\%$; blood vessel invasion: $80.9\%$). According to Lauren's classification, the incidence of intestinal types was 14/21 ($66.7\%$), that of diffuse types was 3/21 ($14.3\%$) and that of mixed types was 4/21 ($19.0\%$). The mean interval between the gastrectomy and the diagnosis of brain metastasis was $24.7\pm4.0$ months (PM: 26.8 months; LM: 20.3 months). The median period of survival after diagnosis of brain metastasis was 2 months for paren chymal metastasis and 0 months for leptomeningeal metastasis. Conclusion:.. During a follow-up period, patients with neurologic symptoms should be suspected of having brain metastasis. Early diagnosis and treatment is the only hope to prolong survival in such patients.

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RADIATION DAMAGE IN THE HUMAN BODY ACUTE RADIATION SYNDROME AND MULTIPLE ORGAN FAILURE

  • AKASHI, MAKOTO;TAMURA, TAIJI;TOMINAGA, TAKAKO;ABE, KENICHI;HACHIYA, MISAO;NAKAYAMA, FUMIAKI
    • Nuclear Engineering and Technology
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    • v.38 no.3
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    • pp.231-238
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    • 2006
  • Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.