• Title/Summary/Keyword: survivor

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Inflammatory Markers as Prognostic Factors for Patients with ARDS (급성 호흡곤란 증후군 환자에서 염증 표지자의 예후 예측인자로서의 역할)

  • Chung, Chae Uk;Hwang, Jae Hee;Park, Ji Won;Shin, Ji Young;Jung, Sun Yuong;Lee, Jeong Eun;Park, Hee Sun;Jung, Sung Soo;Kim, Ju Ock;Kim, Sun Young
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.2
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    • pp.99-104
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    • 2008
  • Background: Acute respiratory distress syndrome (ARDS) is ultimately an inflammatory state. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level are inflammatory markers. The aim of this study was to evaluate the value of the ESR, CRP and APACHE II score as prognostic factors for patient with ARDS. Methods: We retrospectively analyzed the medical records of 87 ARDS patients. The predictors (APACHE II score, ESR and CRP) and outcomes (mortality and length of the total hospital stay, the ICU stay and mechanical ventilator care) were obtained from the patients' records. The patients were grouped according to survival as the Survivor and Non survivor groups. We compared the APACHE II score, the ESR and the CRP level between the survivor group and the nonsurvivor group. We evaluated the correlation between the predictors and the outcomes. The initial ESR, CRP level and APACHE II score were checked at the time of ICU admission and the second ESR and CRP level were checked $3.3{\pm}1.2$ days after ICU admission. Results: Thirty-eight (43.7%) patients remained alive and 49 (56.3%) patients died. The APACHE II score was significantly lower for the survivor group than that for the non survivor group ($14.7{\pm}7.6$ vs $19.6{\pm}9.1$, respectively, p=0.006). The initial ESR and CRP level were not different between the survivor and non-survivor groups (ESR $64.0{\pm}37.8mm/hr$ vs $63.3{\pm}36.7mm/hr$, respectively, p=0.93, CRP $15.5{\pm}9.6mg/dl$ vs $16.3{\pm}8.5mg/dl$, respectively, p=0.68). The decrement of the CRP level for the survivor group was greater than that for the non survivor group ($-8.23{\pm}10.0mg/dl$ vs $-1.46{\pm}10.1mg/dl$, respectively, p=0.003). Correlation analysis revealed the initial ESR was positively correlated with the length of the total hospital stay and the ICU stay (correlation coefficient of the total hospital days: R=0.43, p=0.001, correlation coefficient of the ICU stay: R=0.39, p=0.014). Conclusion: The initial APACHE II score can predict the mortality of ARDS patients, and the degree of the early CRP change can be a predictor of mortality for ARDS patients. The initial ESR has positive correlation with the ARDS patients' duration of the total hospital stay and the ICU stay.

An Analysis of a Reverse Mortgage using a Multiple Life Model (연생모형을 이용한 역모기지의 분석)

  • Baek, HyeYoun;Lee, SeonJu;Lee, Hangsuck
    • The Korean Journal of Applied Statistics
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    • v.26 no.3
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    • pp.531-547
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    • 2013
  • Multiple life models are useful in multiple life insurance and multiple life annuities when the payment times of benets in these insurance products are contingent on the future life times of at least two people. A reverse mortgage is an annuity whose monthly payments terminate at the death time of the last survivor; however, actuaries have used female life table to calculate monthly payments of a reverse mortgage. This approach may overestimate monthly payments. This paper suggests a last-survivor life table rather than a female life table to avoid the overestimation of monthly payments. Next, this paper derives the distribution of the future life time of last survivor, and calculates the expected life times of male, female and last survivor. This paper calculates principal limits and monthly payments in cases of male life table, female life table and last-survivor life table, respectively. Some numerical examples are discussed.

Therapeutic Role of Inhaled Nitric Oxide for Acute Respiratory Failure in the Early Phase of Trauma (외상환자의 초기 호흡 부전에 대한 흡입산화질소의 적용)

  • Kim, Byoung Sung;Kyoung, Kyu-Hyouck;Park, Hojong
    • Journal of Trauma and Injury
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    • v.28 no.3
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    • pp.104-107
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    • 2015
  • Purpose: Nitric oxide (NO) is a vasodilator and inhaled NO (iNO) is used in acute respiratory distress syndrome (ARDS) to improve alveolocapillary gas exchange. The mechanism to improve oxygenation is likely to redistribute blood flow from unventilated areas to ventilated areas. Though improvement of oxygenation, iNO therapy has not been shown to improve mortality and considered as only rescue therapy in severe hypoxemia. We conducted the study to investigate an efficacy of iNO in trauma patients with severe hypoxemia. Methods: We reviewed the trauma patients who underwent iNO therapy retrospectively from 2010 to 2014. Degree of hypoxemia was represented as $PaO_2/FiO_2$ ratio (PFR) and the severity of patient was represented with sequential organ failure assessment (SOFA) score. Patients were divided into the survivor group and non-survivor group according to the 28-day mortality. Results: A total of 20 patients were enrolled. The mortality of 28-day was 40%. There were no significant differences between survivor and non-survivor group in age, sex, severity of injury, PFR and SOFA score. There was significant difference in initiation time of iNO after injury (p=0.047). Maximum combinations of sensitivity and specificity for timing of iNO therapy were observed using cut-off of 3-day after injury with a sensitivity of 88% and specificity of 75%. Conclusion: Though iNO therapy does not influence the mortality, iNO therapy may decrease the mortality caused by respiratory failure in the early phase of trauma.

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Analysis on the Survivor's Pension Payment with Logistic Regression Model (로지스틱 회귀모형을 이용한 유족연금 수급 분석)

  • Kim, Mi-Jung;Kim, Jin-Hyung
    • The Korean Journal of Applied Statistics
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    • v.21 no.2
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    • pp.183-200
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    • 2008
  • Research for efficient management of the National Pension has been emphasized as the current society trends toward aging and low birth rate. In this article, we suggest a statistical model for effective classification and prediction of the reserve for the survivor's pension in Korea. Logistic regression model is incorporated; correct classification rate, and distribution of the posterior probability for the reserve of survivor's pension are investigated and compared with the results from the general logistic models. Assessment of predictive model is also done with lift graph, ROC curve and K-S statistic. We suggest strategies for reducing financial risks in managing and planning the pension as an application of the suggested model.

Risk Assessment for Metalworking Fluids and Respiratory Outcomes

  • Park, Robert M.
    • Safety and Health at Work
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    • v.10 no.4
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    • pp.428-436
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    • 2019
  • Background: Metalworking fluids (MWFs) are mixtures with inhalation exposures as mists, dusts, and vapors, and dermal exposure in the dispersed and bulk liquid phase. A quantitative risk assessment was performed for exposure to MWF and respiratory disease. Methods: Risks associated with MWF were derived from published studies and NIOSH Health Hazard Evaluations, and lifetime risks were calculated. The outcomes analyzed included adult onset asthma, hypersensitivity pneumonitis, pulmonary function impairment, and reported symptoms. Incidence rates were compiled or estimated, and annual proportional loss of respiratory capacity was derived from cross-sectional assessments. Results: A strong healthy worker survivor effect was present. New-onset asthma and hypersensitivity pneumonitis, at 0.1 mg/㎥ MWF under continuous outbreak conditions, had a lifetime risk of 45%; if the associated microbiological conditions occur with only 5% prevalence, then the lifetime risk would be about 3%. At 0.1 mg/㎥, the estimate of excess lifetime risk of attributable pulmonary impairment was 0.25%, which may have been underestimated by a factor of 5 or more by a strong healthy worker survivor effect. The symptom prevalence associated with respiratory impairment at 0.1 mg/㎥ MWF was estimated to be 5% (published studies) and 21% (Health Hazard Evaluations). Conclusion: Significant risks of impairment and chronic disease occurred at 0.1 mg/㎥ for MWFs in use mostly before 2000. Evolving MWFs contain new ingredients with uncharacterized long-term hazards.

Phase Synchronization Algorithm for High-speed Satellite Communications (고속 위성 통신용 위상 동기 방식)

  • ;Duc-Long
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.7A
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    • pp.836-843
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    • 2004
  • In per survivor processing (PSP) has a better performance than conventional phase offset estimators. But itsdefect is that it has a high complexity. In this paper, we propose the adaptive reduced state estimator (ARSE) algorithm not only to reduce the complexity, but also to have a good performance. The main principle of ARSE is changing the number of estimators dynamically during the decoding process according to the channel condition.

Decision-directed channel estimation in TETRA system (TETRA 시스템에서 Decision-directed 기법을 이용한 채널 추정 기법)

  • Hwang, Won-Sik;Lee, Yong-Hwan
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.2C
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    • pp.234-241
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    • 2009
  • TETRA Enhanced Data Service (TEDS), which is an upgrade version of narrow-band ETSI TETRA Release 1 system, can support high speed packet data services in frequency selected fading channel. The performance of M-QAM transceivers employed in the TEDS is significantly affected by the accuracy of channel estimation. In this paper, we consider the design of a decision-directed channel estimation scheme robust to fast fading by estimating the channel by means of a per-survivor processing (PSP) method. The performance of the proposed channel estimation scheme is verified by computer simulation.

Fractals and Fragmentation of Survivor Grains within Gouge Zones along Boundary Faults in the Tertiary Waeup Basin (제3기 와읍분지 경계단층을 따라 발달하는 단층비지 내 잔류입자의 프랙탈과 파쇄작용)

  • Chang, Tae-Woo
    • The Journal of Engineering Geology
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    • v.20 no.2
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    • pp.183-189
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    • 2010
  • Fault gouge samples were collected from the fault cores of the boundary faults between the Cretaceous Basement and the Tertiary Waeup Basin. Fractal dimensions (D) were obtained by using survivor grains which were analysed from six thin sections of the gouges under the optical microscope. The elliptical survivor grains show a shape preferred orientation almost parallel to clay foliation in matrix, suggesting that it was formed by the rotation of the survivor grains in abundant fine-grained matrix during repeated fault slips. The size distributions of the survivor grains follow power-laws with fractal dimensions in the 2.40-3.02 range. D values of all samples but one are higher than a specific D value equal to 2.58 which predicts the self similarity of fragmentation process in constrained comminution model (Sammis et al., 1987), which indicates large fault slip and multiple faulting. Probably the higher D values than 2.58 mean the non-self-similar evolution of cataclastic rocks where fragmentation mechanism changed from constrained comminution to the grain abrasion accompanying selective fracture of larger grains.