• Title/Summary/Keyword: survival inference

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Tolerance by Electric Shock in Hippocampectomized Rats (뇌 해마가 제거된 흰쥐의 전기충격에 대한 내력(耐力))

  • Bai, Sun-Ho;Kim, Chul
    • The Korean Journal of Physiology
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    • v.9 no.1
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    • pp.57-61
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    • 1975
  • A study was designed to clarify the influence of the hippocampus upon tolerance by electric shock. Forty-eight male rats were used, of which 14 rats had their hippocampal tissue on both sides removed through an opening in the parieto-occipital cortex (hippocampal group), 17 rats received damage to the parieto-occipital cortex only (cortical control group), and 17 rats served as normal control animals. After 24 hours' fasting with water ad libitum, each animal was restrained on a plate with added electric shock (4 mA A.C., 1.5 sec in a duration, and once per minute in average) to the tail for the last 24 hours without food and water. The mortality in each animal group and the mean survival time of the dead animal during the repitition of electric shock were calculated. Results obtained were as follows: 1. The mortality was lower significantly in the hippocampal group than in the two control groups. 2. The mean survival time of the dead animal was longer insignificantly in the hippocampal group than in the two control groups. The inference from the above results is that the hippocampus exerts a inhibitory influence upon tolerance by electric shock.

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A Bayesian cure rate model with dispersion induced by discrete frailty

  • Cancho, Vicente G.;Zavaleta, Katherine E.C.;Macera, Marcia A.C.;Suzuki, Adriano K.;Louzada, Francisco
    • Communications for Statistical Applications and Methods
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    • v.25 no.5
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    • pp.471-488
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    • 2018
  • In this paper, we propose extending proportional hazards frailty models to allow a discrete distribution for the frailty variable. Having zero frailty can be interpreted as being immune or cured. Thus, we develop a new survival model induced by discrete frailty with zero-inflated power series distribution, which can account for overdispersion. This proposal also allows for a realistic description of non-risk individuals, since individuals cured due to intrinsic factors (immunes) are modeled by a deterministic fraction of zero-risk while those cured due to an intervention are modeled by a random fraction. We put the proposed model in a Bayesian framework and use a Markov chain Monte Carlo algorithm for the computation of posterior distribution. A simulation study is conducted to assess the proposed model and the computation algorithm. We also discuss model selection based on pseudo-Bayes factors as well as developing case influence diagnostics for the joint posterior distribution through ${\psi}-divergence$ measures. The motivating cutaneous melanoma data is analyzed for illustration purposes.

Cure rate proportional odds models with spatial frailties for interval-censored data

  • Yiqi, Bao;Cancho, Vicente Garibay;Louzada, Francisco;Suzuki, Adriano Kamimura
    • Communications for Statistical Applications and Methods
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    • v.24 no.6
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    • pp.605-625
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    • 2017
  • This paper presents proportional odds cure models to allow spatial correlations by including spatial frailty in the interval censored data setting. Parametric cure rate models with independent and dependent spatial frailties are proposed and compared. Our approach enables different underlying activation mechanisms that lead to the event of interest; in addition, the number of competing causes which may be responsible for the occurrence of the event of interest follows a Geometric distribution. Markov chain Monte Carlo method is used in a Bayesian framework for inferential purposes. For model comparison some Bayesian criteria were used. An influence diagnostic analysis was conducted to detect possible influential or extreme observations that may cause distortions on the results of the analysis. Finally, the proposed models are applied for the analysis of a real data set on smoking cessation. The results of the application show that the parametric cure model with frailties under the first activation scheme has better findings.

On a bivariate step-stress life test (두 개의 부품으로 구성된 시스템의 단계적 충격생명검사에 관한 연구)

  • 이석훈;박래현;박희창
    • The Korean Journal of Applied Statistics
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    • v.5 no.2
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    • pp.193-209
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    • 1992
  • We consider a Step Life Testing which is deviced for a two-component serial system with the considerably long life time. In the modelling stage we discuss the bivariate exponential distribution suggested by Block and Basu as the bivariate survival function for the two-component system, and develope the cumulative exposure model introduced by Nelson so that it can be used under the bivariate function. We consider inference on the component life time when the components are at work in the system by combining the information from system life test and that from the component tests carried out separately under the controlled environment. In data analysis, maximum likelihood estimators are discussed with the initial value obtained by an weighted least square method. Finally we discuss the optimal time for changing the stress in the simple step stress life testing.

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Development of Intelligent Multi-Agent in the Game Environment (게임 환경에서의 지능형 다중 에이전트 개발)

  • Kim, DongMin;Choi, JinWoo;Woo, ChongWoo
    • Journal of Internet Computing and Services
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    • v.16 no.6
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    • pp.69-78
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    • 2015
  • Recently, research on the multi-agent system is developed actively in the various fields, especially on the control of complex system and optimization. In this study, we develop a multi-agent system for NPC simulation in game environment. The purpose of the development is to support quick and precise decision by inferencing the situation of the dynamic discrete domain, and to support an optimization process of the agent system. Our approach employed Petri-net as a basic agent model to simplify structure of the system, and used fuzzy inference engine to support decision making in various situation. Our experimentation describes situation of the virtual battlefield between the NPCs, which are divided two groups, such as fuzzy rule based agent and automata based agent. We calculate the percentage of winning and survival rate from the several simulations, and the result describes that the fuzzy rule based agent showed better performance than the automata based agent.

Assessing Infinite Failure Software Reliability Model Using SPC (Statistical Process Control) (통계적 공정관리(SPC)를 이용한 무한고장 소프트웨어 신뢰성 모형에 대한 접근방법 연구)

  • Kim, Hee Cheul;Shin, Hyun Cheul
    • Convergence Security Journal
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    • v.12 no.6
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    • pp.85-92
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    • 2012
  • There are many software reliability models that are based on the times of occurrences of errors in the debugging of software. It is shown that it is possible to do asymptotic likelihood inference for software reliability models based on infinite failure model and non-homogeneous Poisson Processes (NHPP). For someone making a decision about when to market software, the conditional failure rate is an important variables. The finite failure model are used in a wide variety of practical situations. Their use in characterization problems, detection of outliers, linear estimation, study of system reliability, life-testing, survival analysis, data compression and many other fields can be seen from the many study. Statistical Process Control (SPC) can monitor the forecasting of software failure and there by contribute significantly to the improvement of software reliability. Control charts are widely used for software process control in the software industry. In this paper, we proposed a control mechanism based on NHPP using mean value function of log Poission, log-linear and Parto distribution.

The Assessing Comparative Study for Statistical Process Control of Software Reliability Model Based on polynomial hazard function (다항 위험함수에 근거한 NHPP 소프트웨어 신뢰모형에 관한 통계적 공정관리 접근방법 비교연구)

  • Kim, Hee-Cheul;Shin, Hyun-Cheul
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.8 no.5
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    • pp.345-353
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    • 2015
  • There are many software reliability models that are based on the times of occurrences of errors in the debugging of software. It is shown that it is possible to do parameter inference for software reliability models based on finite failure model and non-homogeneous Poisson Processes (NHPP). For someone making a decision to market software, the conditional failure rate is an important variables. In this case, finite failure model are used in a wide variety of practical situations. Their use in characterization problems, detection of outlier, linear estimation, study of system reliability, life-testing, survival analysis, data compression and many other fields can be seen from the many study. Statistical process control (SPC) can monitor the forecasting of software failure and thereby contribute significantly to the improvement of software reliability. Control charts are widely used for software process control in the software industry. In this paper, proposed a control mechanism based on NHPP using mean value function of polynomial hazard function.

The Assessing Comparative Study for Statistical Process Control of Software Reliability Model Based on Musa-Okumo and Power-law Type (Musa-Okumoto와 Power-law형 NHPP 소프트웨어 신뢰모형에 관한 통계적 공정관리 접근방법 비교연구)

  • Kim, Hee-Cheul
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.8 no.6
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    • pp.483-490
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    • 2015
  • There are many software reliability models that are based on the times of occurrences of errors in the debugging of software. It is shown that it is possible to do likelihood inference for software reliability models based on finite failure model and non-homogeneous Poisson Processes (NHPP). For someone making a decision about when to market software, the conditional failure rate is an important variables. The infinite failure model are used in a wide variety of practical situations. Their use in characterization problems, detection of outlier, linear estimation, study of system reliability, life-testing, survival analysis, data compression and many other fields can be seen from the many study. Statistical process control (SPC) can monitor the forecasting of software failure and thereby contribute significantly to the improvement of software reliability. Control charts are widely used for software process control in the software industry. In this paper, proposed a control mechanism based on NHPP using mean value function of Musa-Okumo and Power law type property.

Analysis of Survivability for Combatants during Offensive Operations at the Tactical Level (전술제대 공격작전간 전투원 생존성에 관한 연구)

  • Kim, Jaeoh;Cho, HyungJun;Kim, GakGyu
    • The Korean Journal of Applied Statistics
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    • v.28 no.5
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    • pp.921-932
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    • 2015
  • This study analyzed military personnel survivability in regards to offensive operations according to the scientific military training data of a reinforced infantry battalion. Scientific battle training was conducted at the Korea Combat Training Center (KCTC) training facility and utilized scientific military training equipment that included MILES and the main exercise control system. The training audience freely engaged an OPFOR who is an expert at tactics and weapon systems. It provides a statistical analysis of data in regards to state-of-the-art military training because the scientific battle training system saves and utilizes all training zone data for analysis and after action review as well as offers training control during the training period. The methodologies used the Cox PH modeling (which does not require parametric distribution assumptions) and decision tree modeling for survival data such as CART, GUIDE, and CTREE for richer and easier interpretation. The variables that violate the PH assumption were stratified and analyzed. Since the Cox PH model result was not easy to interpret the period of service, additional interpretation was attempted through univariate local regression. CART, GUIDE, and CTREE formed different tree models which allow for various interpretations.

Improved Method for Learning Context-Free Grammar using Tabular representation

  • Jung, Soon-Ho
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.2
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    • pp.43-51
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    • 2022
  • In this paper, we suggest the method to improve the existing method leaning context-free grammar(CFG) using tabular representation(TBL) as a chromosome of genetic algorithm in grammatical inference and show the more efficient experimental result. We have two improvements. The first is to improve the formula to reflect the learning evaluation of positive and negative examples at the same time for the fitness function. The second is to classify partitions corresponding to TBLs generated from positive learning examples according to the size of the learning string, proceed with the evolution process by class, and adjust the composition ratio according to the success rate to apply the learning method linked to survival in the next generation. These improvements provide better efficiency than the existing method by solving the complexity and difficulty in the crossover and generalization steps between several individuals according to the size of the learning examples. We experiment with the languages proposed in the existing method, and the results show a rather fast generation rate that takes fewer generations to complete learning with the same success rate than the existing method. In the future, this method can be tried for extended CYK, and furthermore, it suggests the possibility of being applied to more complex parsing tables.