• Title/Summary/Keyword: survival extension

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Effect of Korean Mistletoe (Viscum album coloratum) Extract (KME) on the Extensions of Life span in Silkworm Moth, Bombyx Mori (누에 나방에 있어서 한국산 겨우살이(Viscum album coloratum) 추출물의 생명연장 효과)

  • Jung, Hoe-Yune;Lee, An-Na;Kim, Sae-Jung;Park, Sung-Min;Song, Tae-Jun;Ko, Byung-Woong;Kim, Young-Hoon;An, Hyo-Sun;Yoo, Yung-Choon;Min, Byeng-Ryel;Kim, Jong-Bae
    • Korean Journal of Pharmacognosy
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    • v.39 no.4
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    • pp.310-315
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    • 2008
  • Viscum album coloratum (Korean mistletoe; KM) is a semi-parasitic plant growing on various trees. This plant hasbeen shown to possess a variety of biological functions such as immunomodulation, apoptosis-induction and antitumor activity. However, there is no information about how the extract of KM affects life span of the host. In this study, in order to examine the effect of KM on the longevity of the host, we investigated whether a Korean mistletoe extract (KME) was able to extend the life length in an experimental model using the spring silkworm moth of Bombyx mori (Lepidoptera bombycidae). We established a model test for survival in which all of the male and female moths died within 18 days after the beginning of the experiment. Mean survival time of female moths was longer than that of male moths. Both male and female moths fed with KME containing diet (200 or 400 ${\mu}g$/head/day) showed significantly higher mean survival times than those of the control moths. Studying the effect of KME on prolongation of mean survival time showed that male moths were more susceptible than female moths. The moths fed with KME-containing diet showed a slight decrease in body weight. Interestingly, however, no difference in food intake was observed between moths fed with KME-containing diet and those with control diet. In analysis for mRNA increase in the SIRT2 gene, a member of the Sir2 gene family playing important roles in regulation of cell death and prolongation of life span, moths fed with KME-containing diet showed a significant increase in SIRT2 gene expression. These results suggest that KME has a potential to extend the life span in Bombyx mori, and its effect is partly associated with increase in SIRT2 gene expression.

Comparison of the Colony Development of the Bumblebees, Bombus terrestris Produced from Domestic and Foreign Bumblebees Companies (국내 및 국외 뒤영벌 생산업체별 서양뒤영벌(Bombus terrestris)의 봉세발달 비교)

  • Yoon, Hyung-Joo;Kim, Ji-Yeong;Lee, Kyeong-Yong;Lee, Sang-Beom;Park, In-Gyun;Noh, Si-Kab
    • Korean journal of applied entomology
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    • v.47 no.1
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    • pp.95-100
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    • 2008
  • We compared colony development and survival rate after artificial hibernation between the bumblebees, Bombus terrestris, produced from domestic and foreign companies. The number of worker and queen produced from foundation colony of three domestic and one foreign companies was 232.4-270.8 and 62.0-181.8, respectively, but there was no statistical difference. In colony development of B. terrestris queens which were terminated diapause by $CO_2$ narcosis at different companies, oviposition rate, colony foundation and progeny-queen production of bumblebees produced from domestic companies were superior to those from foreign company. But foreign company in the number of worker and queen was superior to domestic companies. On the other hand, survival rate and colony development of B. terrestris queens, which were terminated diapause by artificial hibernation at three domestic and two foreign companies, were no significant differences. These results indicate that oviposition, colony foundation, progeny-queen production, and survival rate after artificial hibernation showed no differences between the bumblebees produced from domestic and foreign companies.

Prognostic Factors and Clinical Outcome in Parotid Gland Tumors: a Single Institution Experience from the Eastern Black Sea Region of Turkey

  • Kandaz, Mustafa;Soydemir, Gulsen;Bahat, Zumrut;Canyilmaz, Emine;Yoney, Adnan
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1169-1174
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    • 2016
  • Purpose: To review clinical characteristics, treatment outcomes and prognostic factors in patients with parotid gland tumors treated with surgery and postoperative radiotherapy. Materials and Methods: We retrospectively reviewed 69 patients with parotid gland tumors, with a median follow-up of 52 months (range, 2-228 months). and a median radiotherapy dose of 60Gy (range, 30-69 Gy). Results: There were 24 (35%) females and 45 (65%) males, at a ratio of 1/1.9. Median age at presentation was $58.9{\pm}17.2$ (range 13-88) years. The most common histology was adenoid cystic carcinoma (33%) and mucoepidermoid carcinoma (28%). The mean overall survival (OS) was $65.3{\pm}8$ (95% confidence interval [CI], 49.6-81.1) months and the median overall survival was $40.0{\pm}7$ (95% CI, 26.2-53.7) months. The -1, -3, -5 and -10 year OS rates were 78%, 52.4%, 35.3% and 19.6% respectively. The mean disease free survival (DFS) was $79.2{\pm}10$ (95% CI, 59.3-97.1) months and the median disease free survival was $38{\pm}13$ (95% CI, 7.05-88.7) months. The -1,-3,-5 and -10 year DFS rates were 71.9%, 50.1%, 43.7% and 30.1% respectively. On univariate analysis, the OS was significantly better with female sex (p<0.005), < 50 age (p<0.021), T stage (p<0.0001), absence of lymph node involvement (p<0.0001), lower tumor grade (p<0.0001), absence of lymphovascular invasion (p<0.002), absence of perineural invasion (p<0.0001), absence of extracapsuler extension (p<0.0001), surgical margin negativity (p<0.006), ${\leq}60Gy$ radiotherapy dose (p<0.0001) and absence of distant metastasis (p<0.027). Conclusions: Employing existing standards of postoperative radiotherapy is a possible treatment that was found to be mainly effective in patients with parotid gland carcinomas.

Tributyltin chloride (TBTCl) toxicity on the survival rate and burrowing activity of the equilateral venus, Gomphina veneriformis (Bivalvia: Veneridae) (대복, Gomphina veneriformis의 생존 및 저질 잠입성에 미치는 TBTCl의 독성)

  • Park, Jung-Jun;Jin, Young-Guk;Lee, Jung-Sick
    • Journal of fish pathology
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    • v.21 no.1
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    • pp.45-56
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    • 2008
  • This study was conducted to find out biological responses of bivalves exposed to organotin compound.The results of the study confirmed that tribultyltin chloride (TBTCl) induce reduction of survival rate andburrowing activity, and histopathological feature in the foot structure of the equilateral venus, Gomphinaveneriformis. The experimental period was 36 weeks. The experimental groups consisted of a control and 3TBTCl exposure groups (0.4, 0.6, 0.8 ym TBTCl L'). The survival rate and burrowing activity were record-ed daily. For histological analysis, foot tissues were fixed in Bouin' s fluid and then stained H-E stain, AB-PAS (PH 2.5) reaction and Masson's trichrome stain after having serially sectioned the tissue by paraffinmethod at thickness of 4-6 ym. The survival rate was not significantly different between the control andexposure groups for 20 weeks, but in 0.8 Um TBTCl L', it was on the decreased ever since the exposure. Theburrowing activity was not significantly different in the exposure group compared to the control up to 12weeks, but in 0.6 and 0.8 ym TBTCl L', it measured the lowest level after 20 weeks. The foot is composedof the epidermal layer, connective tissue, and muscular layer. The epidermal layer is composed of simplecolumnar, cuboidal epithelia and mucous cells. The cilia were well developed on the apical surface ofepithelium, Circular, longitudinal and transverse muscle bundle were well developed in the muscular layer.The majority mucous cells showed blue color (542c) when it subjected to AB-PAS (PH 2.5) reaction. Nohistopathological alterations in the foot were observed up to 12 weeks. After 20 weeks of exposure to 0.8 (anTBTCl L'', the foot samples of exposed G. veneriformis showed disappearance of cilia and striated borderpartially and extension of hemolymph sinus. The mucous cell increased in the marginal of foot. At 28-weekof exposure to 0.4 ym TBTCl L', it observed weekly acid (564c), neutral (264c) and mixed mucous cell. At36-week of exposure to 0.6 ym TBTCl L', it showed fragmentation of the muscle and collagen fiber bundle,and also diappearance of cilia on epithelia and edema of epithelium in 0.8 ym TBTCl L''.

Effect of Shading and Nitrogen Level on the Accumulation of $NO_3\;^-$ in Leaf of Lettuce(Lactuca Sativa. L.) (차광 및 질소시비량이 상추내 질산염 함량에 미치는 영향)

  • Lee, Gyeong-Ja;Kang, Bo-Goo;Kim, Hyun-Ju;Min, Kyeong-Beom
    • Korean Journal of Environmental Agriculture
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    • v.19 no.4
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    • pp.294-299
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    • 2000
  • In order to find out the effects of shading and nitrogen fertilization on the accumulation of $NO_3\;^-$ in leaves of lettuce, lettuce plants were cultivated in the pots under glasshouse condition with different rates of shading(0, 50%) and nitrogen fertilization(100, 180, 200, 300, $400\;kg{\cdot}ha^{-1}$). The pH value was lower in soil after experiment than before experiment, whereas, contents of EC and $NO_3-N$ were higher. As the amounts of nitrogen fertilization were increased, pHs were decreased, but EC and the contents of $NO_3-N$ were increased. At the nitrogen fertilizations of 100, 180, 200, 300 and $400\;kg{\cdot}ha^{-1}$, the germination rates of lettuce were decreased to 84, 78, 76, 72 and 74%, and survival rates were also decreased to 94, 94, 90, 60 and 46%, respectively. However, the fresh weight of lettuce was highest at $45\;g{\cdot}plant^{-1}$ in the recommended fertilizer $plot(180\;kg{\cdot}ha^{-1})$ with non-shading condition. The contents of $NO_3\;^-$ in the leaves of lettuce were increased 2.8-4.1 times under 50% shading conditions than that under non-shading condition. It kept increasing up to seven order of growth phase; however, it started to decrease after eight order phase. Nitrate reductase activity of lettuce in non-shading condition was higher than that in 50% shading condition.

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The Heterogeneity of T2NO Glottic Carcinoma Treated by Irradiation (T2NO 병기 성문암의 방사선치료-예후인자 분석)

  • Lee Hyung Sik;Moon Sun Rock;Ahn Ki Jung;Chung Eun Ji;Suh Chang Ok;Kim Gwi Eon;Loh John J K
    • Radiation Oncology Journal
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    • v.8 no.2
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    • pp.199-205
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    • 1990
  • During a ten-year period from 1978 through 1987, 44 patients with T2NOMO glottic cancer were treated with radical radiation therapy at the Yonsei University Medical Center. Forty-two patients had a minimum follow-up of 3 years, and $81\%$ had at least five years of follow-up. Patients were staged according to the AJCC system. Forty-two patients have been analyzed in detail with respect to two variables: the status of vocal cord mobility and the degree of local extension of the disease. Five-year local recurrence free survival rates were as follows: All 42 patients, $53.3\%$ patients with normal vocal cord mobility (n =18), $69.1\%$ versus patients with impaired vocal cord mobility (n=24), $43.4\%$(p<0.05); patients with subglottic extension (n=15), $36.7$ versus patients without subglottic extension (n=29), $61.9\%$ (p<0.05). The most favorable Prognostic group included the patients with normal mobility without subglottic extension (n=14), $83.1\%$. On the basis of this analysis, we confirmed the presence of heterogeneity in T2NOMO glottic cancer This study indicates that further randomized controlled trials are warranted to evaluate.

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The Land Use Change and the Desertification in the East Inner Mongolia, China - A Case Study on Horqin Desert - (중국 내몽고 동부지역의 토지이용 변화와 사막화 -커얼친 사지의 사례 -)

  • Lee Kang-Won
    • Journal of the Korean Geographical Society
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    • v.40 no.6 s.111
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    • pp.694-715
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    • 2005
  • I examine in this paper the change of land use and the development of desertification in Horqin desert, east Inner Mongolia, China. The change of land use in this area can be summarized as the increase of agricultural field and intensive livestock farming. The agriculture and livestock farming in semi-arid area such as Horqin desert raised the problem in the management and use of water and vegetation. This problem led to desertification. The types of development of desertification in this area could be classified as follows: the mobile sand dune extension, the riverside shifting sand flat extension, the shifting sand speck extension around settlements, and the shifting sand speck extension in agricultural Held and grassland. There have been political or social movements such as the Great Leap Forward, the Cultural Revolution and the Reform and Open Policy in the background of land use change and desertification. Specially, the Great Leap Forward and the Cultural Revolution played an important role in the land use change and desertification in this area. Since 1990s, there has been some kind of policy in the control of desertification. However, it is necessary for the controling desertification of this area to consider the globalization and marketization, the survival and profit of peasants and livestock farmers, and the disturbrd and fixed population and land use structure in this area since 1949.

Determination of Optimal Collecting Date and Exogenous Auxin Dipping Treatments in Cutting Transplants of 'Seolhyang' Strawberry (Fragaria × ananassa Duch.) ('설향' 딸기 삽목묘의 최적 삽수 채취시기와 오옥신 처리 구명)

  • Kim, Eun Ji;Uhm, Mi Jeong;Jung, Hyun Soo;Kim, Jong Yeob;Lee, Jun Gu
    • Journal of Bio-Environment Control
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    • v.29 no.3
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    • pp.252-258
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    • 2020
  • The aim of this study was to investigate the effects of timing of collecting date and concentration of IBA and NAA, in order to enhance initial activity and seedling quality of domestic strawberry. Strawberry cuttings were separately taken twice, in June 7 and in July 5, and IBA and NAA were treated with the concentrations of 0.025, 0.05 and 0.1% at cutting date, respectively. The seedlings were evaluated for the percentage of survival during 18 days at 6 times after tunnel cultivation. The NAA treatment was inappropriate for strawberry cutting due to the high rate of seedling mortality, regardless of the collecting date. The vitality of the seedlings was highest at IBA 0.1% in June collecting and at IBA 0.05% in July collecting. The seedlings from June collecting had a higher quantum yield at IBA 0.1% and the seedlings from July collecting at IBA 0.05%. Therefore, IBA could be more effectively applied than NAA to promote the vitality and quality with the appropriate concentration of 0.1% at June collecting and 0.05% at July collecting, respectively.

Effects of Temperature on the Development of Gypsy moth (Lymantria dispar) (매미나방(Lymantria dispar) 발육에 미치는 온도의 영향)

  • A-Hae Cho;Hyo-Jeong Kim;Jin-Hee Lee;Ji-in Kim
    • Korean journal of applied entomology
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    • v.62 no.4
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    • pp.385-388
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    • 2023
  • Gypsy moth (Lymantria dispar), a polyphagous insect pest belonging to the family Lymantriidae, is widely distributed in Korea, Japan, Siberia, Europe, and North America. They pose a threat to various host plants including pear trees, apple trees, and blueberries. Traditionally considered a forest pest, the increasing incursion of gypsy moths into agricultural land near forested areas has intensified damage to crops lacking effective control methods. This study aimed to investigate the temperature-dependent development of gypsy moths to enhance outbreak prediction and advance technology development. The effects of temperature on development of each life stage were investigated under constant temperature conditions of 18, 21, 24, 27, 30, and 33℃ (14L:10D, RH 60±5%) utilizing egg masses collected in Jeollanam-do Jangheung-gun in 2021. The results revealed that higher temperatures accelerated the development rate of the gypsy moth larvae with optimal development occurring at 30℃. However, the survival rate was lowest at 33℃. At the favorable temperature of 30℃, the total development period was 43.8 days for females and 42.5 days for males. The developmental threshold temperature were 13.1℃ for females and 12.5℃ for males, with effective accumulated temperature of 641.1 DD and 657.8 DD, respectively.

Several Factors Affecting Seed Emergence, Seedling Quality and Survival of Potted Seedling on Ligularia fischeri (곰취 종자의 발아, 유묘특성 및 분화묘 활착에 미치는 몇 가지 요인)

  • Lee, Ki Cheol;Lee, Su Gwang;Lee, Uk;Noh, Hee Sun;Lee, Jeong Ho
    • Journal of Korean Society of Forest Science
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    • v.105 no.1
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    • pp.63-72
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    • 2016
  • A study was conducted to evaluate the effect of collected region(Bongpyeong in Gangwon, 690 m, Mt. Halla in Jeju, 1,085 m), pre-treatment (stratification, soaked in distilled water or $GA_3$) and shading (control, 50%, 80%) on seed emergence and seedlings growth of Ligularia fischeri. The result showed that seed emergence (%) of L. fischeri were 6.9~75.5% (Gangwon : 6.9~32.8%, Halla : 22.2~75.5%). Maximum seed emergence (%) of 32.8 (Gangwon) and 75.5 (Halla) were achieved for seeds were stratified, soaked in distilled water, and under non-shading for L. fischeri (Gangwon), whereas seeds were stratified, soaked in $GA_3$ 100 ppm, and under 80% shading for L. fischeri (Halla). In this study, the best seedling vigor index (SVI) of L. fischeri (Gangwon) and L. fischeri (Halla) were obtained when seeds were stratified, soaked in distilled water, and under 50% shading. The survival rate of potted seedlings for L. fischeri (Halla) were 100% of all shading conditions, but there were decreased by 77.8%, 61.1%, 55.6%, as an increasing shading rate (con, 50%, 80%) for L. fischeri (Gangwon). Therefore, good seedlings were obtained when seed (Mt. Halla) of L. fischeri were stratified, soaked in distilled water, and under 50% shading, and then seedlings were transferred in pot.