• 대한치주과학회:학술대회논문집
• /
• 대한치주과학회 2005년도 제45회 종합학술대회 연제초록
• /
• pp.225-225
• /
• 2005

• 한국공작기계학회:학술대회논문집
• /
• 한국공작기계학회 1997년도 추계학술대회 논문집
• /
• pp.265-270
• /
• 1997

Helical gear system is utilized to transmit motion between parallel shafts. The axial thrust loads on the shafts are existed. On each of the support shafts, at least one of the bearings should be able to support the axial loads. The reliability and life analysis are based on the two-parameter Weibull distribution lives of the component gears and bearings. The computer calculates the system lives and dynamic capacities of the components and their system. The system life is defined as the life of the component or the helical gear system at an output torque at which the probability of survival is ninety percent.

• Journal of the Korean Data and Information Science Society
• /
• 제7권2호
• /
• pp.263-272
• /
• 1996

임의의 기계에 대한 수명의 분포는 와이블분포를 하는 경우가 흔하다. 그리고 현실적으로 기계의 수명시간을 검정할 때, 시험시간및 여러 환경적인 제약에 의하여 표본으로 주어진 기계의 수명을 모두 관측하기는 어렵다. 그래서, 본 연구에서는 임의 중단모형 하에서 와이블분포의 모수를 최소제곱법(least squares method)을 이용하여 추정하고 기존의 최대우도추정량(maximum likelihood estimates)과 효율성의 측면에서 비교하고자 한다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권16호
• /
• pp.6935-6938
• /
• 2014

Gastric cancer (GC) is one of the most common malignancies worldwide. The ABCB1 protein, a member of the ATP-binding cassette (ABC) transporter family, encoded by the ABCB1 gene, considerably influences the distribution of drugs across cell membranes as well as multidrug resistance (MDR) of antineoplastic drugs. In contrast to the extensive knowledge on the pharmacological action of ABCB1 protein, the correlation between the clinical-pathological data and ABCB1 protein expression in patients with GC remains unclear. The aim was to investigate association between ABCB1 expression and overall survival in GC patients. Human tumor fragments from 57 GC patients were examined by immunohistochemistry assay. We observed lower survival rate of patients with GC who were positive for ABCB1 expression (p=0.030). Based on these observations, we conclude that GC patients with positive ABCB1 protein immunohistochemical expression in their tumors suffer shorter overall survival.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권16호
• /
• pp.7359-7363
• /
• 2015

Background: As a result of significant progress made in treatment of many types of cancers during the last few decades, there have been an increased number of patients who do not experience mortality. We refer to these observations as cure or immune and models for survival data which include cure fraction are known as cure rate models or long-term survival models. Materials and Methods: In this study we used the data collected from 438 female patients with breast cancer registered in the Cancer Research Center in Shahid Beheshti University of Medical Sciences, Tehran, Iran. The patients had been diagnosed from 1992 to 2012 and were followed up until October 2014. We had to exclude some because of incomplete information. Phone calls were made to confirm whether the patients were still alive or not. Deaths due to breast cancer were regarded as failure. To identify clinical, pathological, and biological characteristics of patients that might have had an effect on survival of the patients we used a non-mixture cure rate model; in addition, a Weibull distribution was proposed for the survival time. Analyses were performed using STATA version 14. The significance level was set at $P{\leq}0.05$. Results: A total of 75 patients (17.1%) died due to breast cancer during the study, up to the last follow-up. Numbers of metastatic lymph nodes and histologic grade were significant factors. The cure fraction was estimated to be 58%. Conclusions: When a cure fraction is not available, the analysis will be changed to standard approaches of survival analysis; however when the data indicate that the cure fraction is available, we suggest analysis of survival data via cure models.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권10호
• /
• pp.4219-4222
• /
• 2015

Background: Hydronephrosis is frequently encountered in advanced stage cervical cancers, and may be associated with mortality. In the present study, we aimed to demonstrate the effect of hydronephrosis on survival in patients with inoperable advanced stage cervical cancer. Materials and Methods: The study data were acquired by retrospective analysis of the patient records belonging to 165 women with FIGO (International Federation of Gynecology and Obstetrics) stage-IIIB or more advanced cervical cancer, which were not surgical candidates. Parameters including patient age, pathological diagnosis, disease stage, pelvic sidewall extension, presence of hydronephrosis and administration of chemoradiation were analyzed. Further, the effects of these variables on survival were assessed. P values less than 0.05 were considered statistically significant. Results: The distribution of the study patients according to disease stage was as follows: 131 (79.4%) had stage-IIIB, 18 (10.9%) had stage-IVB and 16 (% 9.7) patients had stage-IVA disease. Hydronephrosis was not evident in 91 (55.2%) of these patients, whereas 41 (24.8%) had unilateral and 33 (20%) patients had bilateral hydronephrosis. When compared to mean survival in patients who did not have hydronephrosis, survival was significantly shortened in patients who had bilateral and unilateral hydronephrosis (p<0.05). There was no significant survival difference between patients with unilateral and bilateral hydronephrosis (p>0.05). Although patient age, pathological type, pelvic involvement, and chemotherapy treatment rates were similar (p>0.05), radiotherapy requirement rate and disease stage were significantly different among the study groups (p<0.05). Conclusions: Hydronephrosis was found to be a significant predictor of poor survival in patients with advanced stage cervical cancer, irrespective of unilateral or bilateral involvement.While waiting for future studies with larger sample sizes, we believe that the FIGO stages in advanced cervical cancer could further be stratified into subgroups according to presence or absence of hydronephrosis.

• 한국시스템다이내믹스연구
• /
• 제16권2호
• /
• pp.53-74
• /
• 2015

Nutria(Myocastor coypus) is one of the most notorious invasive species in many countries. The Nutria's original range was South America like Brazil, Chile and Argentina. But it has been introduced to North America, Europe, Africa, and Asia including Korea, by fur ranchers. Like most invasive and disturbing species, nutria not only destroys habitats but also impacts many native species throughout most of its range with destructive feeding behavior. The purpose of this study is to investigate the dynamics of survival mechanism, population increase and spatial distribution, and eradication effect of Nutria on Nakdong River Area with the systems thinking. The result of this study revealed that Nutria can survive during winter with the behavior that the colder the winter was, the more deeply it burrowed. Further, the study uncovered the dynamics that nutria has survived more and more strongly during the extreme cold winter in almost every region and their population has increased dramatically as a result of the uncontrolled reproduction. Finally, the result showed that the action delay in eradicating Nutria, which was originated from the information delay of perception of nutria's survival and reproduction structure, reinforced the spread of Nutria across the nation.

• 식물분류학회지
• /
• 제51권3호
• /
• pp.181-191
• /
• 2021

Tulips are bulbous geophytes that have considerable commercial value worldwide. This genus primarily originated in the Tien Shan and Pamir-Alai mountain ranges, which surround the Ferghana Valley. The Ferghana Valley is home to five sections of the genus Tulipa L, represented by 23 taxa (22 species). However, there is a lack of detailed information about the distribution of Tulipa species in the natural geographic area of the Ferghana Valley. Therefore, to address this knowledge gap, we comprehensively investigated the spatial distribution of all Tulipa species in the valley. To assess the spatial distribution, the entire area was divided into 32 squares consisting of four latitudinal and eight longitudinal zones. The results showed that latitudinal zones B and C with 15 and 13 taxa, respectively, along with five longitudinal zones (A5, B3, B4, C2, and C3) with 5 to 10 taxa were hotspots for this genus. Additionally, the spatial distributions of the species in terms of the corresponding state borders, mountain ranges, endemism, and conservation issues were assessed. The findings of this study provide comprehensive information about the distribution of Tulipa species to assist with conservation initiatives ultimately to ensure the survival of various species.

• 한국통계학회:학술대회논문집
• /
• 한국통계학회 2003년도 추계 학술발표회 논문집
• /
• pp.39-45
• /
• 2003

Ghosh and Ramamoorthi (1996) studied the posterior consistency for survival models and showed that the posterior was consistent, when the prior on the distribution of survival times was the Dirichlet process prior. In this paper, we study the posterior consistency of survival models with neutral to the right process priors which include Dirichlet process priors. A set of sufficient conditions for the posterior consistency with neutral to the right process priors are given. Interestingly, not all the neutral to the right process priors have consistent posteriors, but most of the popular priors such as Dirichlet processes, beta processes and gamma processes have consistent posteriors. For extended beta processes, a necessary and sufficient condition for the consistency is also established.

• 응용통계연구
• /
• 제25권3호
• /
• pp.423-434
• /
• 2012

A two-sample test for equality of survival distribution is one of the important issues in survival analysis, especially for clinical and epidemiological research. With interval censored data, some testing methods have been developed. This study introduces some testing methods and compares them under various situations through simulation study. Based on simulation result, it provides some useful information on choosing the most appropriate testing method in a given situation.