• 약학회지
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• 제53권2호
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• pp.74-77
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• 2009

Food deprivation decreases hepatic glutathione (GSH) levels, which is ascribed to alterations in availability of hepatic cysteine, a rate limiting factor for the GSH synthesis. The present study examines the effects of food deprivation on hepatic metabolism of sulfur amino acid in male rats. In rats fasted for 24 or 48 hours, hepatic GSH levels were decreased from $6.70{\pm}0.16{\mu}mol/g$ liver to $4.02{\pm}0.20$ or $4.06{\pm}0.07{\mu}mol/g$ liver, respectively. Hepatic S-adenosylmethionine levels were also decreased in fasted rats, but S-adenosylhomocysteine levels were increased. Hepatic methionine levels were not changed by food deprivation for 48 hours. On the other hand, hepatic cysteine or taurine levels were increased from $106.2{\pm}4.1$ to $130.0{\pm}2.7$ nmol/g liver or from $2.45{\pm}0.43$ to $5.07{\pm}0.78{\mu}mol/g$ liver, respectively, in 48-hour fasted rats. Activity of cystathionine beta-synthase catalyzed homocysteine to cystathionine, was markedly decreased, but activity of betaine homocysteine methyltransferase was increased in fasted rats, indicating that methylation of homocysteine to methionine is activated. Also activity of cysteine dioxygenase, involved in taurine synthesis, was increased. These results suggested that hepatic methionine levels were maintained in rats fasted for 48 hours through increase in homocysteine methylation, and hepatic GSH may serve as a cysteine supplier reservoir in fasting state.

• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 2001년도 The Seoul International Simulation Conference
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• pp.37-43
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• 2001

New product development has been a key element fur organizational evolution. The bulk of research about new product strategy has focused solely on new product development function itself. This paper investigates cross-functional elements in new product development. More specifically, we suggest that there must exist a fit between new product strategy and value chain strategy. It means that, in order to support new product development activity, there must exist a relevant value chain strategy. We consider three types of integration - internal integration, customer integration, and supplier integration - as strategic elements of value chain strategy. For the case of new product strategy, we consider market newness and product technology unfamiliarity as strategic elements. We also consider two types of learning characteristic, i.e., \\\"fast-adaptive learning\\\" and \\\"slow-adaptive leaning\\\" as control factor. Learning characteristic represents firms organizational capability related with organizational learning. For example, fur fast-adaptive learning case, the effect of integration appears early in time. System dynamics simulation is employed to verify our research framework. The results exhibit that there must exist cross-functional relationships between value chain strategy and new product strategy in order to shorten total development time.al development time.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2010년도 춘계 학술논문 발표대회 1부
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• pp.125-129
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• 2010

The ultimate goal of construction is to complete the given work in the most economical and safest way within the required construction period while meeting the quality standards specified in the design drawing. There are a few characteristics of finish work. First, executed in subdivided processes, finish work involves a very diverse and complex structure. Second, there are no criteria for each segmented process with regard to the appropriate time of input. Third, it is not very necessary to set priorities for lead and lag works. This study intends to provide information on the completion of a project in accordance with the required duration by setting priorities in the delay of each detailed process of finish work to minimize delay in finish work. In this study, finish work is divided into wet work and other types of finish work, and the importance of each process is classified based on the given details of each process. In addition, the study employs a survey to analyze delay factors of a designer, a constructor, and a supplier. Using the survey results, the study sets priorities in delay of final work to provide information on the completion of an apartment project within the planned construction period.

• Asia pacific journal of information systems
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• 제9권2호
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• pp.77-97
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• 1999

industry each which are using a kind of EDI, supplier-oriented Electronic Data Interchange(SOEDI) to procure materials, equipment and supplies more effectively. The major objective of this study are to determine the basic nature of the impact of SOEDI on the structure and procedure in purchasing. The other is to identify the variables or determinants which influence the benefits which can be experienced in purchasing organizations. This study was conducted through interviewing of organizations which are currently active in the use of EDI. Samples of 107 purchasing organizations were collected. Some key findings of this study are ; 1) There were remarkable differences on influencing level and relationship of determinants which influence the benefits of purchasing organizations. There was the most remarkable one in trading industry. 2) The more suppliers, the more benefits. The transaction rate with suppliers who are affiliated with EDI is low as a whole but suppliers who are affiliated with EDI can be a critical factor on selection of buyers. 3) Procedure related to purchasing order was mainly changed. There is a development on signature but still exists. 4) The number of employees were reduced a little bit.

• 한국연초학회지
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• 제22권1호
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• pp.91-98
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• 2000

This study was carried out to evaluate the uncertainty in the analysis of menthol content from the mentholated cigarette. Menthol in the sample cigarette was extracted with methanol containing an anethole as an internal standard, and then analyzed by gas chromatography. As the sources of uncertainty associated with the analysis of menthol, were the following points tested, such as the weighing of sample, the preparation of extracting solution, the pipetting of extracting solution into the sample, the preparation of standard solution, the precision of GC injections for standard & sample solution, the GC response factor of standard solution, the reproducibility of menthol analysis, and the determination of water content in tobacco, etc. For calculating the uncertainties, type A of uncertainty was evaluated by the statistical analysis of a series of observation, and type B by the information based on supplier's catalogue and/or certificated of calibration. Sources of uncertainty were subsequently included and mathematically combined with the uncertainty arising from the assessment of accuracy to provide the overall uncertainty. It was shown that the main source of uncertainty came from the errors in the reproducibility of menthol and water determination, the purity of menthol reference material in the preparation of standard solution, and the precision of GC injections for sample solution. The errors in sample weighing and volume measurement contributed relatively little to the overall uncertainty. The expanded uncertainty in the mentholated cigarettes, Korean and American brand, at 0.95 level of statistical confidence was $\pm$0.06 and $\pm$0.07 mg/g for a menthol content of 1.89 and 2.32 mg/g, respectively.

• Journal of Information Technology Applications and Management
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• 제22권4호
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• pp.205-224
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• 2015

Information System is a critical success factor for overcoming the limitations of asset and capacity of Small and Medium Enterprises (SME), and for acquiring competitiveness. Although, the rate of adopting information system by SME has grown, the rate of its utilization has been stagnant. The purpose of this study is to identify the influencing factors that increase SME's information system utilization. We identify perception of strategic value, supplier's support capacity, and organizational characteristic by examining previous researches on information system utilization by SMEs, and verify their the influencing relationship with the information system utilization. This study verifies the research model and hypothesis using structural model. A date-set of 1209 samples from a survey on employees in charge of information system of SME was applied in verifying the research hypothesis. The result of this study shows that the information system utilization influences perception of strategic value and support of supply company, and partly, the structural characteristics. This study presents directions to establish strategy and policy making, and theoretically presents core factors of SME's information system utilization.

• 펄프종이기술
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• 제32권5호
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• pp.67-71
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• 2000

The history of the paper industry has shown a strong technological evolution which has been an essential factor in achieving low cost, high quality paper products and in sustaining the strength of the industry. In the last decades paper machine development has been rapid. This has helped to establish paper as a "low cost" material. In future, the pressure from the competing media will only accelerate the technological efforts to improve cost and functional'||'&'||'not;ity of paper. In addition, in the future, technological advances will be combined with innovation in busi'||'&'||'not;ness concepts. Certain production methods are likely to be developed which will distribute current process stages outside the paper mill. Papermakers can begin to reduce their invest'||'&'||'not;ment risk by subcontracting large-scale base paper production but taking responsibility for the higher value finishing process stages. Finishing will be more closely integrated with the final use. The role of technology supplier to the paper industry will naturally evolve to reflect all these changes. Metso is already actively collaborating downstream in the different paper-related business chains. This collaboration will be crucial for implementation of new business and technology innovations in P'||'&'||'P industry and Metso will certainly benefit from its catalyst role in this transition.

• 유통과학연구
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• 제20권12호
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• pp.89-98
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• 2022

Purpose: Due to the rapid growth of e-commerce in Thailand, the operational excellence of distribution service providers has been elevated. Thus, this research investigated the key drivers of operational performance of e-commerce distributors in Thailand. The research contains key variables: the analytics capabilities of an organization, supply chain disruption orientation, innovation capability, and operational performance. Research design, data, and methodology: An online survey is administered to top managers and key personnel (N=425) employed for at least one year in Thailand's top five e-commerce distributors. The sampling methods were conducted using purposive sampling, quota sampling, and convenience sampling. Confirmatory Factor Analysis and Structural Equation Model were applied to analyze and confirm the model's goodness-of-fit and hypothesis testing. Results: The findings reveal that an organization's analytics capabilities significantly affect supply chain disruption orientation and supply chain resilience. Furthermore, operational performance is affected by supply chain disruption, supplier quality management, and innovation capability. Nevertheless, supply chain resilience and digital supply chain have no significant effect on operational performance. Conclusions: The results imply that supply chain digitalization could drive higher operational performance. Distribution businesses are encountering transformation and disruption, which should address the high level of a digital supply chain, innovation, and quality management to maximize their profit margin and delivery service quality.

• 한국융합학회논문지
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• 제9권9호
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• pp.217-228
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• 2018

중소 제조 기업 중심으로 ERP를 도입함에 있어 경쟁회사와의 차별화, 비용 우위 전략이 필요하다고 보는 관점에서 효과적인 ERP 구축전략을 할 수 있는 길잡이 역할을 목표로 하고 있다. 구축 전략으로 차별화 및 비용우위와 서비스 품질이 도입성과에 종속관계, 매개효과를 살펴보았다. 첫째, 차별화 나 비용우위전략은 재무적 성과에는 선행연구 결과를 지지하고 있다. 하지만 차별화 전략에서는 비재무적 관점에서만 유의하였다. 둘째, 차별화와 비용우위 전략은 서비스 품질 요인 확신성만 재무적 성과가 있고 나머지 서비스 품질은 도입 성과에는 유의하지 않은 것으로 분석되었다. 셋째, 컨설팅 서비스 품질의 매개효과 분석은 차별화나 비용우위 전략 경로에서 모두 유의하지 않았다. 결론적으로 시스템 구축은 구축 전략으로는 재무적 관점에서 차이가 있으며, 서비스 품질 요인에서는 공급업체가 제공하는 확신성 즉 지식 및 확신과 믿음을 줄 수 있는 능력에 영향이 있다.

• 한국의류학회지
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• 제31권1호
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• pp.95-106
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• 2007

The purpose of this study is to investigate the relationship between the implementation and the performance of the eSCM in internet shopping malls, and to suggest collaborated strategy for internet shopping malls. We performed the surveys of suppliers for 3 fashion-specialized internet shopping malls and 3 general internet shopping mall. Additional surveys was performed by surveying the shopping mall merchandisers to research the differences of understandings on the performance of the eSCM between shopping malls and their suppliers. Total 143 questionnaries were distributed and collected from January 23 to February 28, 2006 and analyzed by SPSS 10.0. The results are as follows; 1) the efficiency of eSCM is related the factors of partnership and information, and among the subordinated factors the understanding and support of the top management, good communications, product and operating information sharing were find out to be significant. 2) The effectiveness of eSCM is influenced by the organizational and partnership factor. As the subordinated factors, the understanding and supports of the top management, the participations of members, good communications, good relationship and supports, and the technology level of eSCM were identified as significant. 3) Examining the differences of understandings on the performance of eSCM between the suppliers and the shopping mall merchandisers, the suppliers and the merchandisers show different opinions on the operating efficiency, and the customer service.