• Title/Summary/Keyword: supercritical carbon dioxide extraction

Search Result 134, Processing Time 0.023 seconds

The Study on the Composition of Yongdamsagan-tang(龍膽瀉肝湯)'s Essential Oil Obtained by Supercritical Carbon Dioxide Extraction (초임계 유체 추출법을 이용한 용담사간탕(龍膽瀉肝湯) 약침액(藥鍼液)의 정유(精油)성분에 대한 연구(硏究))

  • Lee, Jae-Eun;Kim, Byeong-U;Im, Tae-Jin;Kim, Dong-Hui;Shin, Min-Seop;Yook, Tae-Han;Gwon, Gi-Rok
    • Journal of Pharmacopuncture
    • /
    • v.11 no.1
    • /
    • pp.177-187
    • /
    • 2008
  • Objectives : This study was performed to analyze the effective components of essential oil obtained from Yongdamsagantang, which has been efficacious against leukorrhea in gynecologic diseases. Methods : I obtained the essential oils of Yongdamsagan-tang by hydrodistillation extraction method and supercritical fluid extraction(SFE) method, and then I analyzed those by GC/MS(Gas Chromatography/Mass Spectrum). Results : 1. The optimum SFE(Supercritical Fluid Extraction) condition was obtained in the following experiment conditions: pressure 200atm, temperature $45^{\circ}C$, duration of extraction 25minutes. 2. With GC(Gas Chromatography) and GC/MS(Gas Chromato- graphy/Mass Spectrum) analysis, I identified 37 compounds in the Yongdamsagan-tang's essential oil obtained through the SFE method. The main compounds were as follows : 3-Methyl-but-2-enoic acid,2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H -pyrano[3,2-g]chromen-3-yl ester(49.81%), (Z)-6-Pentadecen-1 -ol(3.19%), (-)-Spathulenol(2.40%). 3. I identified 4 compounds in the Yongdamsagan-tang's essential oil obtained through the hydrodistillation method. The main compounds were as follows : 3-Methyl-but-2-enoic acid, 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano [3,2-g]chromen-3-yl ester(2.61%). 4. 3-Methy I-but-2-enoic acid, 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g] chromen-3-yl ester, all were identified in both the SFE method and the hydrodistillation method, but the others were not identified in common. 5. I also conducted an additional test in order to examine the essential oil's antimicrobial action against bacteria. Both MIC(Minimum Inhibitory Concentrations) and MBC(Minimum Bactericidal Concentrations) were $0.125mg/m{\ell}$ against N. meningitidis, however MIC and MBC were $1.0mg/m{\ell}$ in antimicrobial action against 12 different genera of bacteria.

Ultrasound-Assisted Extraction of Canola Oil Using Supercritical Fluid Process (초음파가 적용된 초임계 유체 공정을 이용한 캐놀라오일 추출)

  • Hwang, Ah-Reum;Lim, Gio-Bin;Ryu, Jong-Hoon
    • KSBB Journal
    • /
    • v.25 no.5
    • /
    • pp.437-442
    • /
    • 2010
  • The objective of this study was to investigate the effect of ultrasound on the extraction of oil from canola seeds when supercritical carbon dioxide ($SCCO_2$) was used as an extraction solvent. The ultrasound-assisted $SCCO_2$ extraction were carried out while varying such operating parameters as particle size of crushed canola seed, flow rate of $SCCO_2$, aspect ratio of the extraction vessel, and ultrasound power. The extraction rate decreased with increasing particle size of samples, showing a maximun at a $CO_2$ flow rate of 6.2 L/min. Both the extraction rate and extraction yield increased with a decrease in the aspect ratio of the extraction vessel. For the ultrasoundassisted $SCCO_2$ extraction, the extraction yield was slightly increased when the $CO_2$ flow rate was below 6 mL/min with sample A and B.

Process conditions of valuable compound for benign prostatic hyperplasia(BPH) from saw palmitto by supercritical CO2 (초임계 CO2를 이용한 Saw palmitto로부터 전립선 비대 유효 성분의 추출 조건)

  • 류병호;조경자
    • Journal of Life Science
    • /
    • v.13 no.5
    • /
    • pp.569-575
    • /
    • 2003
  • Supercritical $CO_2$ extraction was applied to extraction of the valuable compound for benign prostatic hyperplasia from saw palmitto. Three levels of parameters, temperature $(35^{\circ}C,\; 60^<\circ}C)$, pressure 22∼30 Mpa and ethanol modified solvent concentration, were used as the independent variables of central composite to rotate the design. The extracting pressure and temperature interaction was significantly affected the extraction of valuable compounds. The ethanol was an efficient modifier to extract valuable compound by supercritical carbon dioxide. The optimal processing conditions were extracting pressure, 30 Mpa, extracting temperature, $60^<\circ}C$, ethanol modifier, 15% for extracts of the valuable compounds from saw palmitto. In conclusion, it was found that supercritical $CO_2$ extraction can successfully be applied to extract high quality extracts from saw palmitto.

Preparation of Poly(N-vinyl-2-pyrrolidone) Microparticles Using Supercritical Anti-solvent (초임계 반용매법을 이용한 폴리비닐피롤리돈 미세입자의 제조)

  • Shin, Moon-Sam;Kim, Hwa-Yong
    • Clean Technology
    • /
    • v.14 no.4
    • /
    • pp.242-247
    • /
    • 2008
  • Poly(N-vinyl-2-pyrrolidone) (PVP) has been used as biocompatible and biodegradable polymer in cosmetics, pharmaceuticals and electronics. Micro-particles of PVP were produced using an aerosol solvent extraction system (ASES). Dichloromethane (DCM) and supercritical carbon dioxide were used as solvent and antisolvent, respectively. The mean diameter of the obtained polymer particles ranged from 0.184 to $0.249\;{\mu}m$. The relationship between particle size and initial drop size was also considered.

  • PDF

Physicochemical properties of supercritical carbon dioxide defatted mealworm (Tenebrio molitor) powder and protein isolate (초임계이산화탄소 탈지 밀웜(Tenebrio molitor) 분말 및 분리단백의 이화학적 품질 특성)

  • Kim, Yangji;Kim, Seok Joong
    • Korean Journal of Food Science and Technology
    • /
    • v.52 no.5
    • /
    • pp.516-523
    • /
    • 2020
  • Supercritical carbon dioxide (SCO2) extraction was applied for the defatting of mealworm to prepare defatted powder (DP) and protein isolate (PI) and compare the process to press and hexane extraction, with respect to DP and PI physicochemical properties. SCO2 DP was obtained by extracting 34.40% oil at 41.37 MPa, 40℃ for 180 min, and the product contained 71.66% crude protein, which is similar to that of hexane DP and higher than that of press DP. In using alkali protein extraction to prepare PI from DP, SCO2 was as effective as hexane and better than press. SCO2 produced brighter DP and PI than press, but not as much as hexane. Protein solubility was similar in all DP, with minimum values at pH 5. The highest water adsorption capacity was noticeable for SCO2 PI, and SCO2 DP showed an oil adsorption capacity comparable to that of hexane DP. SCO2 DP and PI had better foaming capacity than press DP and PI and showed superior emulsion activity compared to others.

Phospholipids Isolation from Squid Viscera Residues After Supercritical Carbon Dioxide Extraction (오징어 내장의 초임계 이산화탄소 추출 잔류물로부터 인지질의 분리)

  • U, Pyoung-Ook;Chun, Byung-Soo
    • Korean Chemical Engineering Research
    • /
    • v.48 no.6
    • /
    • pp.741-746
    • /
    • 2010
  • Phospholipids were recovered from squid viscera residues by ethanol extraction after supercritical carbon dioxide($SCO_2$) extraction and from squid viscera was not processed $SCO_2$ by various organic solvent extraction. $SCO_2$ extraction were performed at $45^{\circ}C$ and 20 MPa for removal of non polar lipid molecules from freeze dried squid viscera sample. Phospholipids were extracted from freeze dried squid viscera sample by chloroform, hexane, methanol, and ethanol and from $SCO_2$extracted squid viscera sample by ethanol. The pH was fixed at 5.7 for all phospholipids extraction conditions. Phospholipid classes were analyzed by HPLC equipped with evaporative light scattering detector (ELSD). Phosphatidyl choline(PC) extracted by ethanol from $SCO_2$ extracted residues was higher than that of extracted by ethanol from squid viscera. But phosphatidyl ethanolamine(PE) and phosphatidic acid(PA) were extracted higher percentage in raw squid viscera. The fatty acid compositions in phospholipids extract by ethanol extract from $SCO_2$ extracted residues were analyzed by gas chromatography(GC). Docosahexanoic acid(DHA) was found in highest percentage in phospholipid extract.

Extraction of Glabridin from Licorice Using Supercritical Carbon Dioxide (초임계 이산화탄소를 이용한 감초 중의 glabridin 추출)

  • Cho Yun-Kyoung;Kim Hyun-Seok;Kim Ju-Won;Lee Sang-Yun;Kim Woo-Sik;Ryu Jong-Hoon;Lim Gio-Bin
    • KSBB Journal
    • /
    • v.19 no.6 s.89
    • /
    • pp.427-432
    • /
    • 2004
  • The purpose of this study is to investigate the feasibility of a cosolvent-modified supercritical $CO_2\;(scCO_2)$ extraction technique for the production of licorice extracts with high levels of glabridin. The effects of various parameters such as the type and amount of modifiers, extraction temperature ($40{\sim}80^{\circ}C$) and pressure ($10{\sim}50.0\;MPa$) on the extraction efficiency were examined at a fixed flow rate of 1 mL/min. The organic solvent extraction with pure methanol was also conducted for a quantitative comparison with the $scCO_2$ extraction. The recovery of glabridin from licorice was found to be extremely small for pure $scCO_2$. However, the addition of modifiers such as ethanol and acetone to $scCO_2$ resulted in a significant improvement in the recovery of glabridin. The recovery of glabridin was observed to increase with pressure at a constant temperature. Furthermore, the purity of the glabridin obtained from the $scCO_2$ extraction was higher compared with the organic solvent extraction.

Lipid Extraction from Nannochloropsis sp. Microalgae for Biodiesel Production Using Supercritical Carbon Dioxide (초임계 이산화탄소를 이용한 Nannochloropsis sp. 미세조류로부터 바이오디젤 생산용 지질의 추출)

  • Choi, Kyung-Seok;Ryu, Jae-Hun;Park, Dong-Jun;Oh, Sea-Cheon;Kwak, Hyun
    • Korean Chemical Engineering Research
    • /
    • v.53 no.2
    • /
    • pp.205-210
    • /
    • 2015
  • In this paper, microalgae lipid extractions were performed using conventional organic solvent and supercritical carbon dioxide (SC-$CO_2$) for biodiesel-convertible lipid fractions. The highest levels (58.31%) of fatty acid methyl ester (FAME) content in the lipid extracted by SC-$CO_2$ was obtained, and 18.0 wt.% crude lipid yield was achieved for Bligh-Dyer method. In the SC-$CO_2$ extraction, methanol as a co-solvent was applied to increase the polarity of extract. The experimental results indicated that crude lipid yield, FAME content and yield extracted by combination of SC-$CO_2$ with methanol were 12.5 wt.%, 56.32% and 7.04 wt.%, respectively, and this method could reduce the extraction time from 2 hour to 30 min when compared to SC-$CO_2$ extraction. Therefore, SC-$CO_2$ extraction is proven to be an environmentally-friendly and an effective method for lipid extraction from microalgae.

Extraction of Ginger Oil from Korean-Grown Ginger-root using Supercritical Carbon Dioxide (초임계 이산화탄소를 이용한 국산 생강뿌리로부터 생강유의 추출)

  • 천재기
    • Journal of the Korean Graphic Arts Communication Society
    • /
    • v.16 no.1
    • /
    • pp.69-79
    • /
    • 1998
  • The type photographic optical system is designed by using numerical method. Initially the paraxial quantites, numerical solutions are found for the system which is free from the Seidel seven aberrations. The final system has f/4 with the half field angle 20$^{\circ}$, and the image size is 36mm with the focal length of 50mm.

  • PDF