• Journal of The Korea Institute of Healthcare Architecture
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• v.10 no.1
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• pp.39-45
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• 2004

This thesis is a case study of hospital design corresponding to substance of hospital components. The substance of each divisions and functional elements of hospital architecture is analyzed and the appropriate forms corresponding to each substance are tried in design. The researcher is convinced, that healthcare facilities for patients must be differently designed from post-modernism or deconstructivism. He suggests new design method in designing of jeju university hospital competition.

• Journal of the Korean Society of School Health
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• v.13 no.1
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• pp.161-169
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• 2000

이 연구에서 우리는 건강 교육 프로그램을 통해서 청소년 건강 복지를 향상시키는 방법을 추구해본다. 흡연, 음주, 약물 남용의 패턴은 전형적으로 틴에이지 시기에 형성되어진다. 청소년들은 다양한 심리 사회적 이유 때문에 substance 사용을 시작한다. 정책 수립자들의 우선 과제는 청소년들을 교육시키는 것이어야한다. 이 연구에서는 청소년 substance 사용 행위가 종단적 관점에서 연구되어진다. 청소년 substance 사용 행위 예방 교육 프로그램으로부터 얻어진 종단 데이터가 이 연구에서 사용되어진다. 건강 교육 프로그램을 도입했던 학교들에서 청소년 substance 사용 행위가 더 작은 율로 중가되는 것이 보여지고, 그 효과성이 검증되어진다.

• Applied Biological Chemistry
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• v.35 no.3
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• pp.202-209
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• 1992

In order to study on the viscous substance produced during Chungkookjang fermentation, one strain which produce a lot of viscous substance was isolated from the rice straw and identified as Bacillus sp; This strain produced the most viscous substance in 48 hours at $42^{\circ}C$, in splite of little change of amino type nitrogen and ammonia type nitrogen when added M.S.G., while the yield of viscous substance and amino type nitrogen was increased but that of ammonia type nitrogen was decreased when added susrose. Molecular weight of viscous substance estimated between 15,000 and 65,000. Viscous substance was confirmed mostly composed of glutamate and fructose by G.C. and HPLC analysis. Composition of viscous substance would be controlled according to the changes of media.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.135-148
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• 2005

Objective : The purpose of this study is to take around the oriental medical treatment about substance related disorder in china. Method : We review the studies which are published by six different journal in China since 1992 to 2002 involved in substance related disorders. Result 1. The kinds of substance which is the subject of each study. It suggest that the narcotics-withdrawal patients in china take kinds of opium many more than phillopon or barbiturate, cocain etc. especially the heroine takes the most portion in the kinds of opium. 2. The type of chinese medicine demonstration which is about the addiction and withdrawal. There are many symptoms in the each period of withdrawal, According to the each period demonstration, the herbal formula must be different. 3. The formula used in treatment and the substance which is used in common Codonopsis radix is widely used, and pinellia ternata, aractylodes japonica, citrus nobilis, vegetable worms, angelica gigas, zizyphus jujuba, panax ginseng, astragalus membranaceus etc are also used in treatment. 4. The methods of acupunture treatment Hapkok(LI-4), Naegwan(PC6), and Sanyinjiao(SP6) are the widely used acu-points. in addition to these acupoints, there are waegwan(TE5) choksamli(ST36) hanggan(LR2)etc. Conclusion : We expect that this review about substance related disorders in TCM help the clinical study of substance related disorders in Korean medicine.

• Journal of Preventive Medicine and Public Health
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• v.51 no.1
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• pp.23-32
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• 2018

Objectives: To identify the associations of characteristics of the neighborhood environment with substance abuse among clients receiving treatment for drug abuse in Thailand. Methods: A cross-sectional study was conducted of 1128 drug addicts from 28 neighborhoods who were receiving treatment at all 7 compulsory drug detention centers in Thailand. A trained interviewer conducted structured interviews with the subjects about substance use and the perceived neighborhood environment in their community. A multilevel logistic regression model was applied to estimate the effects of the neighborhood environment on substance use. Results: The majority of participants, 53.8% only used methamphetamine pills, 31.3% used other illicit drugs as well as methamphetamine pills, and 14.9% used an illicit drug other than methamphetamine. Three neighborhood characteristics were associated with substance use. A 1-unit increase in the perceived neighborhood cohesion score was associated with a 15% reduction in methamphetamine pill use and an 11% reduction of the use of both methamphetamine pills and another illicit drug. Conversely, a 1-unit increase in perceived neighborhood crime predicted 19 and 14% increases in the use of methamphetamine pills and the use of both methamphetamine pills and another illicit drug, respectively. In addition, a 1-unit increase in the scores for stigma surrounding addiction corresponded to a 25% increase of the use of methamphetamine pills and a 12% increase in the use of both methamphetamine pills and another illicit drug. Conclusions: Substance use among drug addicts was influenced by characteristics of the neighborhood environment. Therefore, prevention and intervention strategies should be designed based on a consideration of the impact of neighborhood context on substance use behaviors.

• The Korean Journal of Pain
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• v.19 no.2
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• pp.168-174
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• 2006

Background: Several biochemical mediators, such as substance P, calcitonin gene-related peptide (CGRP) and prostaglandin $E_2$, have been demonstrated to be involved in herniated or degenerated disc-induced radiculopathy. The authors tested the hypothesis that these mediators would existed in the epidural space of humans. Methods: Thirty nine patients were divided into two groups; 27 patients, who were diagnosed with spinal stenosis (stenosis group), and 12 scheduled for epidural anesthesia, without a history of back pain (control group). Under fluoroscopic guidance, an epidural catheter was introduced through the caudal space and placed into the anterior and posterior spaces, up to and around the epidural adhesive area, in the stenosis group. In the control group, the catheter was placed into the posterior epidural space through the L3⁣-4 or L4⁣-5 intervertebral space. Epidural irrigation was performed with 10 ml of saline, via an epidural catheter. Aspirated lavage fluid was collected, and the concentrations of biochemical mediators (substance P, CGRP and prostaglandin $E_2$) measured using an enzyme immunoassay kit. Results: Substance P, CGRP and prostaglandin $E_2$ were detected in all the epidural lavage fluids from both groups. The concentrations of substance P and prostaglandin $E_2$ in the stenosis group were higher than those of the control (P < 0.05). However, there was no difference in the CGRP levels between the two groups. In the stenosis group, the concentrations of these three mediators in the anterior epidural space were no different to those in the posterior space. Conclusions: These results suggest that biochemical mediators, such as substance P and prostaglandin $E_2$, in the epidural space might be partly involved in pain mechanism associated with spinal stenosis.

• Advances in Traditional Medicine
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• v.6 no.2
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• pp.112-120
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• 2006

The purpose of this study was to analyze whether quantitative evaluation of the color of the tongue substance using $L^*a^*b^*$ color coordinates system could minimize the problems arising from the different illuminating conditions or not. In controlled 4 different illuminating conditions (by natural light, flashlight, f-number, shutter speed),12 healthy subjects were photographed of their tongue substance through a digital camera (C-2100uz, Olympus Co.), both on the top surface and on the bottom surface of the tongue substance by two examiners, twice at 3 day intervals. Clinician evaluation was also performed grading the redness of the tongue substance in the form of 5-points scale by 6 clinicians. As a result, there was no significant difference in color differences between the color of the tongue substance and the reference red card in the 4 different illuminating conditions. Intra-rater reliability was satisfied and even though limitedly, inter-rater reliability was satisfied. Color differences were significantly correlated with the results by the clinicians, although they were applicable limitedly to specific illuminating conditions. Our results indicate that the application of the color differences in tongue diagnosis could not only evaluate the color information quantitatively, but also minimize the problems arising from the different illuminating conditions and that there was the significant difference in the visual evaluation of the red color of the tongue substance, both between the clinicians and between the illuminating conditions.

• The Journal of the Korea Contents Association
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• v.21 no.11
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• pp.723-732
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• 2021

The aim of this study is to investigate the effect of substance use experience with adolescents on the problem gambling and to verify moderating effect of irrational gambling beliefs. A part of data from Korea Center on Gambling Problems, in which 1,500 adolescents participated was analyzed. The research findings were as follows. First, among the demographics factors, sex, monthly allowance, among the independent variable, substance use experience and irrational gambling beliefs showed significant difference on problem gambling. Second, substance use experience and irrational gambling beliefs tended to increase problem gambling. Third, the interaction of substance use experience and irrational gambling beliefs moderated the relationship between substance use experience and problem gambling. Based on these results, this study discussed practical measures to manage substance use and to prevent problem gambling among adolescents.

• Microbiology and Biotechnology Letters
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• v.20 no.1
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• pp.110-113
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• 1992

In the screening process of anti- or desmutagenic substance from the various microbial metabolites with the method of Ames and Rec-assay, a desmutagenic substance producing bacterial strain which inactivates the mitomycin C-induced mutagenicity was isolated and identified as Psudomonas sp. AM-10.

• Analytical Science and Technology
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• v.15 no.4
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• pp.1039-1050
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• 2002