• The Journal of the Korea Contents Association
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• v.19 no.6
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• pp.236-248
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• 2019

Green belts can help to set boundary for city growth, provide ecological protection system and enhance the resilience of Beijing. During the implementation period of the current overall city planning of Beijing, the proportion of green space varies much among the sub-districts, villages and towns involved in the two green belts in the research. With this as starting point, by researching the correlations of 'city system factors' and 'planning policy factors' with the change in the scale of green space, the paper discussed the influential factors of implementing the planning of green space of Beijing, and conducted quantitative research, with such possible influential factors classified into 'city system factors' and 'planning policy factors'. Through multiple linear regression model, the paper tested the correlations of city system factors and planning policy factors (independent variable) with the increment in the construction land in green belts (dependent variable). Through influence to population aggregation and the expansion force of construction land, city system factors such as mountain land and water, house rent of unit area, accessibility of public transport and the newly-defined state-owned construction land generate correlation with the change in the scale of construction land in green belts.

• Journal of Korean Society of Rural Planning
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• v.25 no.2
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• pp.89-98
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• 2019

The purpose of this study is to develop the evaluation factors for formation of the future - oriented rural residential environment and to derive the importance of this evaluation factors. The main research methods are network analysis using Net-miner, AHP analysis and importance analysis for experts. The main research results are as follows. First, 6 factors for evaluation rural residential environment(environmental-sustainability, communality, self-reliance, aesthetic, enjoyment, settlement), 3 sub-factors of each factors, and key physical facilities(10 for rural center and 28 for rural villages) were derived by literature analysis and network analysis on it. Second, key priority factors that should be considered in physical formation of rural residential environment was deducted by AHP analysis. Improving accessibility of living services in the settlement factor, improvement of garbage collection and wastewater treatment system around the residential area, and ensuring topographic continuity in the environmental-sustainability factor was derived as a priority factors. Third, as a result of evaluation of the importance of physical facilities in the rural residential environment, there was a high demand for cultural welfare facilities in common. However, when compared with the villages where the harmony between the natural environment and the living environment is emphasized, convenience of living and accessibility of transportation were important in the rural center. These results suggest that solving the qualitative conditions as residential environment will help to attract new population. This study will contribute to enhance the qualitative level of the rural residential environment by suggesting strategic priority items when carrying out projects related to the rural residential environment creation in the future.

• Journal of Korean Society on Water Environment
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• v.35 no.1
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• pp.43-54
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• 2019

The objective of this study was to assess the effect of policies on water quality management based on the changes in pollutants and water quality in Special Water Preservation Area (SWPA) of Lake Paldang watershed from 1990 to 2016. The population, total sewage and flow rate of wastewater in SWPA continuously increased from 1990 to 2016, while the location of new facilities for industrial and livestock facilities has been restricted. However, unlike the buffer zone in which industrial and livestock facilities were continuously reduced after implementing of TMDL, it was found that the effect of land-use regulations on industrial and livestock facilities in SWPA were mitigated by the increase in the size of large facilities. Since 1999 when the emission standard of public sewage treatment plants (STP) was changed, the water quality of Lake Paldang has increased despite the increase of pollutant source. Since emission standard of STP changed in 2012 (BOD 5 mg/L, TP 0.2 mg/L), BOD concentration in Lake Paldang has also improved to the level of water quality in the early 1990s where as TP concentration has remained at its lowest since 1990. BOD and TP average discharge concentration of 43 STP (${\geq}500m^3/day$) in 2016 have been maintained $1.7{\pm}0.7mg/L$ and $0.06{\pm}0.02mg/L$ respectively. While the discharged load of STP in SWPA was decreased by the concentration management, the contribution rate to the total discharged load of non-point pollutants increased to 70 % in 2015, and the contribution rate to the point discharged load of individual treatment facilities increased to 80 %.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.2
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• pp.21-37
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• 2021

Objectives : Allergic rhinitis(AR) is a common chronic disease that accounts for 10-40% of the world's population. This study aims to analyze the status of claims, prevalence, and medical utilization of allergic rhinitis patients using representative patients sample data. Methods : This study used the National Patients Sample(HIRA-NPS) of the Health Insurance Review and Assessment Service for 7 years(2010-2016). And we defined AR patients as all statements including J30 or a subcategory of J30 as the main disease, using the Korean Standard Classification of Diseases(KCD-7). The trend of AR patients by year was divided into Western medicine(WM) and Korean medicine(KM), and analyzed by subgroup analysis such as inpatient/outpatient, gender, age, insurance type, and care institution. Results : Patients with AR were mainly claimed for first sub diagnosis in WM and major diagnosis in KM, and the number of claims increased about 1.3 times and 1.4 times compared to 2010 in WM and KM, respectively. In addition, the total annual medical expenses in 2016 increased 1.3 times and 1.7 times compared to 2010, respectively. Conclusions : Both WM and KM are showing a steadily increasing trend in medical use due to allergic rhinitis. Further research is needed by considering genetic and environmental factors and individual characteristics, and linking with additional data.

• The Korean Journal of Franchise Management
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• v.10 no.4
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• pp.7-18
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• 2019

Purpose: This study identifies the relative importance of the sub - factors of initial services and continuous services using AHP (Analytic Hierarchy Process) method, and calculates the competitive index for the detailed factors. The purpose of this paper is to propose the establishment of long - term and short - term management strategy for expansion of business of food service franchise, franchisors, long - term and win - win relationship with franchisees, and rationalization of operating system. Research design, data, and methodology: The population for the survey is 92 franchisees in 46 foreign brands and 46 domestic brands in the Seoul metropolitan area (Seoul / Gyeonggi / Incheon). The survey was conducted from July 1 to August 31, 2018 through the survey agency with a telephone interview and a surveyor's direct visit. A total of 100 questionnaires were collected, but a total of 92 parts were used for analysis except 8 parts that were considered to contain false information. Using the AHP method, relative importance and competitiveness index were calculated for the details of initial services and continuous services. Results: The results shows continuous services were significantly higher for both foreign brand franchises, domestic brand franchises, and overall than initial services, This suggests that the continuous services of the affiliated franchisors has a higher relative importance than the initial services. Among the continuous services, brand reinforcement and promotion were significantly higher for both foreign brand merchants and domestic brand franchises. This can be regarded as the most important factor in brand reinforcement and promotion when selecting a food service franchisors. Conclusions: In the Standard Terms and Conditions governed by the Fair Trade Commission, the franchisors should increase the fairness by creating manuals for supporting services, especially after opening, and regularly checking whether the supporting services have been carried out like manuals since the establishment of franchisees. In addition, the Brand Strengthening and Public Relations Committee (tentative name) jointly participated by the franchisors and franchisees for the purpose of strengthening and promoting the brand, suggesting a system for transparent and efficient execution of the brand reinforcement and promotion budget and monitoring afterwards.

• 한국사회정책
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• v.24 no.1
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• pp.213-237
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• 2017

It is essential in social policy evaluation to examine how effectively they protect people from social risks. The aim of this study is to evaluate the effectiveness of five income security programs of Korea in coping with poverty, using KoWEPs data. We analyse the coverage and adequacy of these programs, joint as well as individual, for each sub-groups. As a result, it was found that 35% of the poor get none of the benefits. The coverage and adequacy for the aged is rather high. However, for the working age people, the unemployed in particular, are very poorly covered and average benefits levels are very low. These findings imply that there are much room and demand for improvement of Korean income security program, especially for working age population.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.18 no.6A
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• pp.115-127
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• 2008

The Native API is a system call which can only be accessed with the authentication of the administrator. It can be used to detect a variety of malicious codes which can only be executed with the administrator's authority. Therefore, much research is being done on detection methods using the characteristics of the Native API. Most of these researches are being done by using supervised learning methods of machine learning. However, the classification standards of Anti-Virus companies do not reflect the characteristics of the Native API. As a result the population data used in the supervised learning methods are not accurate. Therefore, more research is needed on the topic of classification standards using the Native API for detection. This paper proposes a method for re-grouping malicious codes using fuzzy clustering methods with the Native API standard. The accuracy of the proposed re-grouping method uses machine learning to compare detection rates with previous classifying methods for evaluation.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.211-215
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• 2021

The number of megacities are increasing, due to the global urbanization. Along with this change, climate change, social development and technology advance make the calamities complicated and more devastating. Especially, megacities are hyper-netted, hyper-connected and hyper-converged with population more than 10 million and their domain. When calamities break out, the damage will be aggravated for they lead to another ones. Since megacities are the center of politics, economics and culture of a nation. so when complex disaster break out in megacities, this may be developed to a peril to the national security. Therefore, pan-government effort must be concentrated in preparing abilities to forecast, react, rapid response and resilience.

• Journal of Applied Biological Chemistry
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• v.64 no.1
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• pp.97-102
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• 2021

In this study, enzymes were screened for hydrolysis of defatted perilla seed residue (DPSR) and optimal conditions for enzymatic treatment were determined to produce the hydrolysate of DPSR. Also its antioxidant activity and utilization as a culture medium were examined. The combined treatment of Alcalase and Ceremix is most effective for solubilization of protein and carbohydrate in DPSR. The optimal dosage, pH, and reaction time for enzymatic treatment were found to be 2.0% (w/w), 7.0, and 2 h, respectively. Treatment with optimal conditions of enzymes dramatically increased reducing sugar, soluble protein, and total phenolic content. The hydrolysate of DPSR possessed better scavenging activity against cation and free radicals than enzyme-untreated extract. When Leuconostoc mesenteroides 310-12 was cultured in the hydrolysate of DPSR, cell population rapidly increased compared to enzyme-untreated extract, and titratable acidity increased in proportion to the bacterial growth. In conclusion, these results imply that the hydrolysate of DPSR could be utilized as a bacteria culture medium as well as a physiologically active material with antioxidant activity.

• BMB Reports
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• v.54 no.12
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• pp.608-613
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• 2021

Melanoma, the most serious type of skin cancer, exhibits a high risk of metastasis. Although chemotherapeutic treatment for metastatic melanoma improves disease outcome and patient survival, some patients exhibit resistance or toxicity to the drug treatment regime. OTUB1 is a deubiquitinating enzyme overexpressed in several cancers. In this study, we investigated the effects of inhibiting OTUB1 expression on melanoma-cell proliferation and viability and identified the underlying molecular mechanism of action of OTUB1. We did endogenous OTUB1 knockdown in melanoma cells using short interfering RNA, and assessed the resulting phenotypes via MTT assays, Western blotting, and cell-cycle analysis. We identified differentially expressed genes between OTUB1-knockdown cells and control cells using RNA sequencing and confirmed them via Western blotting and reverse transcription polymerase chain reaction. Furthermore, we investigated the involvement of apoptotic and cell survival signaling pathways upon OTUB1 depletion. OTUB1 depletion in melanoma cells decreased cell viability and caused simultaneous accumulation of cells in the sub-G1 phase, indicating an increase in the apoptotic-cell population. RNA sequencing of OTUB1-knockdown cells revealed an increase in the levels of the apoptosis-inducing protein TRAIL. Additionally, OTUB1-knockdown cells exhibited increased sensitivity to PLX4032, a BRAF inhibitor, implying that OTUB1 and BRAF act collectively in regulating apoptosis. Taken together, our findings show that OTUB1 induces apoptosis of melanoma cells in vitro, likely by upregulating TRAIL, and suggest that approaches targeting OTUB1 can be developed to provide novel therapeutic strategies for treating melanoma.