• 제목/요약/키워드: structure-function relationship

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Mathematical Programming Models for Establishing Dominance with Hierarchically Structured Attribute Tree (계층구조의 속성을 가지는 의사결정 문제의 선호순위도출을 위한 수리계획모형)

  • Han, Chang-Hee
    • Journal of the military operations research society of Korea
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    • v.28 no.2
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    • pp.34-55
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    • 2002
  • This paper deals with the multiple attribute decision making problem when a decision maker incompletely articulates his/her preferences about the attribute weight and alternative value. Furthermore, we consider the attribute tree which is structured hierarchically. Techniques for establishing dominance with linear partial information are proposed in a hierarchically structured attribute tree. The linear additive value function under certainty is used in the model. The incompletely specified information constructs a feasible region of linear constraints and therefore the pairwise dominance relationship between alternatives leads to intractable non-linear programming. Hence, we propose solution techniques to handle this difficulty. Also, to handle the tree structure, we break down the attribute tree into sub-trees. Due to there cursive structure of the solution technique, the optimization results from sub-trees can be utilized in computing the value interval on the topmost attribute. The value intervals computed by the proposed solution techniques can be used to establishing the pairwise dominance relation between alternatives. In this paper, pairwise dominance relation will be represented as strict dominance and weak dominance, which ware already defined in earlier researches.

Assignment of the Carbonyl Carbon Resonances in Anti-Dansyl Antibodies (항 단실 항체의 카르보닐탄소 유래 시그날의 귀속)

  • ;;Koichi Kato;Yoji Arata
    • YAKHAK HOEJI
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    • v.39 no.5
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    • pp.516-520
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    • 1995
  • The anti-dansyl antibodies were specifically labeled with stable isotope by growing hybridoma cells in serum-free medium. Assignments of the observed carbonyl carbon resonances have been determined by using $^{13}C-{15}N$ double labeling method in order to assign the Leu resonances. However, when the identical dipeptide appears more than twice in the polypeptide sequences, we applied the proteolytic fragments in the fragment-specific method. Carboxypep-tidase B-treated antibody has also been used to assign the Lys-447 in C terminal amino acid. These unambiguously assigned carbonyl carbon resonances in antibodies are thought to be useful in elucidating not only the structure of antibodies but also the structure-function relationship in the antibody by $^{13}C$ neuclear magnetic resonance spectroscopy.

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APPLICATION OF THE BIFOCUSING METHOD IN MICROWAVE IMAGING WITHOUT BACKGROUND INFORMATION

  • SEONG-HO SON;WON-KWANG PARK
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.27 no.2
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    • pp.109-122
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    • 2023
  • In this study, we consider the application of the bifocusing method (BFM) for identifying the locations and shapes of small anomalies from scattering parameter data when the exact values of background permittivity and conductivity are unknown. To this end, an imaging function using numerical focusing operator is introduced and its mathematical structure is revealed by establishing a relationship with an infinite series of Bessel functions, antenna arrangements, and anomaly properties. On the basis of the revealed structure, we demonstrate why inaccurate location and size of anomalies were retrieved via the BFM. Some simulation results are illustrated using synthetic data polluted by random noise to support the theoretical result.

Changing Wheat Quality with the Modification of Storage Protein Structure

  • Tamas, Laszlo;Bekes, Ferenc;Morrell, Matthew K.;Appels, Rudi
    • Journal of Plant Biotechnology
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    • v.1 no.1
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    • pp.13-19
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    • 1999
  • The visco-elastic properties of gluten are major determinants of the processing properties of doughs. These visco-elastic properties are strongly influenced by the ratio of monomeric and polymeric proteins and the size distribution of the polymeric proteins, which make up the gluten fraction of the dough. Recent studies have revealed that other features, such as the number of the cysteine residues of the HMW-GS, also play an important role in determining the functional characteristics. To modify the processing properties at molecular level, the relationship between the structure of molecules and dough properties has to be understood. In order to explore the relationships between individual proteins and dough properties, we have developed procedures for incorporating bacterially expressed proteins into doughs, and measuring their functional properties in small-scale equipment. A major problem in investigating the structure/function relationships of individual seed storage proteins is to obtain sufficient amounts of pure polypeptides from the complex families of proteins expressed in the endosperm. Therefore, we have established a simplified model system in which we produce specific protein genes through bacterial expression and test their functional properties in smallscale apparatus after incorporation into base flour. An S poor protein gene has been chosen as a template gene. This template gene has been modified using standard recombinant DNA techniques in order to test the effects of varying the number and position of cysteine residues, and the size of the protein. Doughs have been mixed in small scale apparatus and characterized with respect to their polymeric composition and their functional properties, including dough mixing, extensibility and small scale bating. We conclude that dough characteristics can be manipulated in a predictable manner by altering the cysteine residues and the size of high molecular weight glutenins.

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Sediment Bacterial Community Structure under the Influence of Different Domestic Sewage Types

  • Zhang, Lei;Xu, Mengli;Li, Xingchen;Lu, Wenxuan;Li, Jing
    • Journal of Microbiology and Biotechnology
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    • v.30 no.9
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    • pp.1355-1366
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    • 2020
  • Sediment bacterial communities are critical to the biogeochemical cycle in river ecosystems, but our understanding of the relationship between sediment bacterial communities and their specific input streams in rivers remains insufficient. In this study, we analyzed the sediment bacterial community structure in a local river receiving discharge of urban domestic sewage by applying Illumina MiSeq high-throughput sequencing. The results showed that the bacterial communities of sediments samples of different pollution types had similar dominant phyla, mainly Proteobacteria, Actinobacteria, Chloroflexi and Firmicutes, but their relative abundances were different. Moreover, there were great differences at the genus level. For example, the genus Bacillus showed statistically significant differences in the hotel site. The clustering of bacterial communities at various sites and the dominant families (i.e., Nocardioidaceae, and Sphingomonadaceae) observed in the residential quarter differed from other sites. This result suggested that environmentally induced species sorting greatly influenced the sediment bacterial community composition. The bacterial co-occurrence patterns showed that the river bacteria had a nonrandom modular structure. Microbial taxonomy from the same module had strong ecological links (such as the nitrogenium cycle and degradation of organic pollutants). Additionally, PICRUSt metabolic inference analysis showed the most important function of river bacterial communities under the influence of different types of domestic sewage was metabolism (e.g., genes related to xenobiotic degradation predominated in residential quarter samples). In general, our results emphasize that the adaptive changes and interactions in the bacterial community structure of river sediment represent responses to different exogenous pollution sources.

Digital Item Purchase Model in SNS Channel Applying Dynamic SNA and PVAR

  • LEE, Hee-Tae;JUNG, Bo-Hee
    • Journal of Distribution Science
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    • v.18 no.3
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    • pp.25-36
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    • 2020
  • Purpose: Based on previous researches on social factors of digital item purchase in digital contents distribution platforms such as SNS, we aim to develop the integrated model that accounts for the dynamic and interactive relationship between social structure indicators and digital item purchase. Research design, data and methodology: A PVAR model was used to capture endogenous and dynamic relationships between digital item purchase and network indicators. Results: We find that there exist considerable endogenous and dynamic relationships between digital item purchase and network structure variables. Not only lagged in-degree and out-degree but also in-closeness and out-closeness centrality have significant and positive impacts on digital item purchase. Lagged clustering has a significant and negative effect on digital item purchase. Lagged purchase has a significant and positive impact just on the present in-closeness and out-closeness centrality; but there is no significant effect of lagged purchase on the other two degree variables and clustering coefficient. We also find that both closeness centralities have much higher carryover effect on digital item purchase and that the elasticity of both closeness centralities on the purchase of digital items is even higher than that of other network structure variables. Conclusions: In-closeness and out-closeness are the most influential factors among social structure variables of this study on digital item purchase.

A Study of the Curved Line as a Survival -Especially Centered on the Physical Structure- (생존으로서의 곡선(曲線)에 관한 연구 -물리적 구조법칙을 중심으로-)

  • 박규현;신기봉;박영민
    • Archives of design research
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    • v.15 no.1
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    • pp.181-190
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    • 2002
  • Every object's patterns is the balancing-relationship between the object's inner-energy and outer-stress. To see this as a balancing-relationship between an organism, inner-energy would be the occurrence of thermodynamic entropy which is for its existing maintenance. Outer-stress would be the friction that comes from the surrounding environment. Namely, we can see that object's figure exists in the balance between an extort to survive and fiction that disturb it. However, it is fourth that these figures are consisted of a curve and curved-surface which is not a straight line. So, it is impossible to find a figure made up of straight lines and surfaces in the existing object's world. It's true that we have regarded only a curve as the beautiful. Here, we have presented that in a curve, there exists an important function which protect our survival from the ancient humanity. And by closely observing the function in a physical dynamic-pattern sight, we've searched what is important in the design's origin that handle curve-patterns. Of course it would be more reasonable to analyze it in the standpoint of Mathematics, Chemistry, or Biology, and synthesize the points. However, due to the limitation of the researchability, we will concern about the physical structure in the design. Deficient details will be replenished through the study between educational systems. As a result, we have confirmed that, devoting the curve's physical structure-phenomenon (occurred in nature) to the design, is more beautiful in our eyes, too.

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Diagnostics of Diffuse Two-Phase Matter Using Techniques of Positron Annihilation Spectroscopy in Gamma-Ray and Optical Spectra

  • Doikov, Dmytry;Yushchenko, Alexander;Jeong, Yeuncheol
    • Journal of Astronomy and Space Sciences
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    • v.36 no.3
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    • pp.115-119
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    • 2019
  • This paper is a part of the series on positron annihilation spectroscopy of two-phase diffuse gas-and-dust aggregates, such as interstellar medium and the young remnants of type II supernovae. The results obtained from prior studies were applied here to detect the relationship between the processes of the annihilation of the K-shell electrons and incident positrons, and the effects of these processes on the optical spectra of their respective atoms. Particular attention was paid to the Doppler broadening of their optical lines. The relationship between the atomic mass of the elements and the Doppler broadening, ${\Delta}{\lambda}_D$ (${\AA}$), of their emission lines as produced in these processes was established. This relationship is also illustrated for isotope sets of light elements, namely $^3_2He$, $^6_3Li$, $^7_3Be$, $^{10}_5B$ and $^{11}_5B$. A direct correlation between the ${\gamma}-line$ luminosity ( $E_{\gamma}=1.022MeV$) and ${\Delta}{\lambda}_D$ (${\AA}$) was proved virtually. Qualitative estimates of the structure of such lines depending on the positron velocity distribution function, f(E), were made. The results are presented in tabular form and can be used to set up the objectives of further studies on active galactic nuclei and young remnants of type II supernovae.

Inverse model for pullout determination of steel fibers

  • Kozar, Ivica;Malic, Neira Toric;Rukavina, Tea
    • Coupled systems mechanics
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    • v.7 no.2
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    • pp.197-209
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    • 2018
  • Fiber-reinforced concrete (FRC) is a material with increasing application in civil engineering. Here it is assumed that the material consists of a great number of rather small fibers embedded into the concrete matrix. It would be advantageous to predict the mechanical properties of FRC using nondestructive testing; unfortunately, many testing methods for concrete are not applicable to FRC. In addition, design methods for FRC are either inaccurate or complicated. In three-point bending tests of FRC prisms, it has been observed that fiber reinforcement does not break but simply pulls out during specimen failure. Following that observation, this work is based on an assumption that the main components of a simple and rather accurate FRC model are mechanical properties of the concrete matrix and fiber pullout force. Properties of the concrete matrix could be determined from measurements on samples taken during concrete production, and fiber pullout force could be measured on samples with individual fibers embedded into concrete. However, there is no clear relationship between measurements on individual samples of concrete matrix with a single fiber and properties of the produced FRC. This work presents an inverse model for FRC that establishes a relation between parameters measured on individual material samples and properties of a structure made of the composite material. However, a deterministic relationship is clearly not possible since only a single beam specimen of 60 cm could easily contain over 100000 fibers. Our inverse model assumes that the probability density function of individual fiber properties is known, and that the global sample load-displacement curve is obtained from the experiment. Thus, each fiber is stochastically characterized and accordingly parameterized. A relationship between fiber parameters and global load-displacement response, the so-called forward model, is established. From the forward model, based on Levenberg-Marquardt procedure, the inverse model is formulated and successfully applied.

Depression in Schizophrenia Patients with Tardive Dyskinesia (지연성 이상운동이 있는 조현병 환자의 우울증)

  • Cha, Seongjae;Oh, Keun;Kim, Misuk;Park, Seon-Cheol;Kim, Young Hoon
    • Korean Journal of Biological Psychiatry
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    • v.25 no.4
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    • pp.110-117
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    • 2018
  • Objectives This study aimed to investigate the relationship between depressive and anxiety symptoms and tardive dyskinesia (TD) and reveal the association of cognitive function and TD in patients with schizophrenia. Methods We recruited 30 schizophrenia patients with TD and 31 without TD from a national mental hospital in South Korea. To assess depressive and anxiety symptoms, the Beck Depression Inventory-II (BDI-II) and the Beck Anxiety Inventory (BAI) were conducted. Using the five-factor structure of the BDI-II and BAI, somatic anxiety, cognitive depression, somatic depression, subjective anxiety, and autonomic anxiety were assessed. Computerized neurocognitive function test (CNT) was performed to assess levels of cognitive functions. We compared the clinical characteristics, levels of cognitive functions, and depressive and anxiety symptoms between schizophrenia patients with TD and without TD. Chi-square test, Fisher's exact test, independent t-test and Mann Whitney U test were conducted to compare two groups. Pearson correlation analysis was conducted to evaluate relationships among the abnormal involuntary movement scale (AIMS), BDI-II, BAI, somatic anxiety, cognitive depression, somatic depression, subjective anxiety, and autonomic anxiety. Results The subjects with TD had significantly lower score on the cognitive depression than those without TD (t = -2.087, p = 0.041). There were significant correlations between the AIMS score and the BDI-II score (r = -0.386, p = 0.035) and between the AIMS score and cognitive depression score (r = - 0.385, p = 0.035). Conclusions Our findings suggest the inverse relationship between severities in TD and depression and support the assumption that there is an inverse relationship between the pathophysiology of TD and depression.

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