• 한국자기공명학회논문지
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• 제23권1호
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• pp.26-32
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• 2019

${\alpha}B$-crystallin (${\alpha}BC$) is a member of a small heat-shock protein (sHSP) superfamily and plays a predominant role in cellular protein homeostasis network by rescuing misfolded proteins from irreversible aggregation. ${\alpha}BC$ assembles into dynamic and polydisperse high molecular weight complexes containing 12 to 48 monomers; this variable stereochemistry of ${\alpha}BC$ has been linked to quaternary subunit exchange and its chaperone activity. The chaperone activity of ${\alpha}BC$ poses great potential as therapeutic agents for various neurodegenerative diseases. In this mini-review, we briefly outline the recent advancement in structural characterization of ${\alpha}BCs$ and its potential role to inhibit protein misfolding and aggregation in various human diseases. In particular, nuclear magnetic resonance (NMR) spectroscopy and its complimentary techniques have contributed much to elucidate highly-dynamic nature of ${\alpha}BCs$, among which notable advancements are discussed in detail. We highlight the importance of resolving the structural details of various ${\alpha}BC$ oligomers, their quaternary dynamics, and structural heterogeneity.

• Structural Monitoring and Maintenance
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• 제9권4호
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• pp.305-321
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• 2022

Bridge structural health monitoring with the aim of continuously assessing structural safety and reliability represents a topic of major importance for worldwide infrastructure managers. In the last two decades, due to their potential economic and operational advantages, drive-by approaches experienced growing consideration from researcher and engineers. This work addresses two technical topics regarding indirect frequency estimation methods: bridge and vehicle dynamics overlapping, and bridge expansion joints impact. The experimental campaign was conducted on a mixed multi-span bridge located in Lombardy using a Ford Galaxy instrumented with a mesh of wireless accelerometers. The onboard time series were acquired for a number of 10 passages over the bridge,performed at a travelling speed of 30 km/h, with no limitations imposed to traffic. Exploiting an ad-hoc sensors positioning, pitch vehicle motion was compensated, allowing to estimate the first two bridge bending frequencies from PSD functions; moreover, the herein adopted approach proved to be insensitive to joints disturbance. Conclusively, a sensitivity study has been conducted to trace the relationship between estimation accuracy and number of trips considered in the analysis. Promising results were found, pointing out a clear positive correlation especially for the first bending frequency.

• 농촌지도와개발
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• 제30권1호
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• pp.31-41
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• 2023

This study aims to examine the structural relationships among rurality perception, tourism attitude, and behavioral intention in rural healing tourism. Particularly, this study focused on the mediation effect of attitude. Data were collected from 658 rural healing tourists by online survey. SPSS 28.0 and AMOS 28.0 were used for frequency, exploratory factor, confirmatory factor, and structural equation modeling analyses. The results of structural equation modeling indicate perception of rurality had a positive effect on attitude and behavioral intention. In addition, attitude mediated the relationships between perception of rurality and behavioral intention. The results of this study suggest the importance of understanding the interests and pursuits of rural healing tourists and providing them with the values they want. Since rurality has a direct influence on attracting healing tourists, it is necessary to establish a positive image of rural healing tourism.

• Structural Engineering and Mechanics
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• 제86권2호
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• pp.249-260
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• 2023

The uncertainties involved in structural performances are of importance when the optimum number and property of seismic retrofit devices are determined. This paper proposes a seismic retrofit design framework for asymmetric soft-first-story buildings, considering uncertainties in the soil condition and seismic retrofit device. The effect of the uncertain parameters on the structural performance is used to find a robust and optimal seismic retrofit solution. The framework finds a robust and optimal seismic retrofit solution by finding the optimal locations and mechanical properties of the seismic retrofit device for different realizations of the uncertain parameters. The structural performance for each realization is computed to evaluate the effect of the uncertainty parameters on the seismic performance. The framework utilizes parallel processing to decrease the computationally intensive nonlinear dynamic analysis time. The framework returns a robust design solution that satisfies the given limit state for every realization of the uncertain parameters. The proposed framework is applied to the seismic retrofit design of a five-story asymmetric soft-first-story case study structure retrofitted with a viscoelastic damper. Robust optimal parameters for retrofitting a structure to satisfy the limit state for the different realizations of the uncertain parameter are found using the proposed framework. According to the performance evaluation results of the retrofitted structure, the developed framework is proved effective in the seismic retrofit of the asymmetric structure with inherent uncertainties.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2022년도 봄 학술논문 발표대회
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• pp.227-228
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• 2022

In order to achieve the goal of cost management, which is one of the three major management goals of building production, this paper introduces an approximate cost estimating automation technology in the design stage as the importance of predicting construction costs increases. BIM is used for accurate estimating, and the quantity of structural members and finishing materials is calculated by creating a 3D model of the actual building. However, only 2D basic design drawings are provided when making an estimating. Therefore, for accurate quantity calculation, digitization of 2D drawings is required. Therefore, this research calculates the quantity of concrete structural members by calculating the area for the recognition area through 2D drawing recognition technology incorporating computer vision. It is judged that the development technology of this research can be used as an important decision-making tool when predicting the construction cost in the design stage. In addition, it is expected that 3D modeling automation and 3D structural analysis will be possible through the digitization of 2D drawings.

• 한국콘텐츠학회논문지
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• 제15권8호
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• pp.532-543
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• 2015

자연재해에 따른 SOC시설물의 피해는 구조물 자체의 안전성에 위험뿐 아니라 시설물을 이용하는 국민들에게 경제 사회적인 측면에서 직간접적으로 막대한 영향을 미친다. 특히, 인구밀도가 높은 대도시지역에서는 이러한 영향이 더 크게 나타나기에 재난재해등의 위험이 발생하였을 경우 지역내 중요시설물이 어떤 것이 있는가를 파악하고 관리해야 할 것이다. 본 논문에서는 시설물이 가지고 있는 시설물별 중요한 인자를 도출하고 전문가를 대상으로 AHP분석기법을 통해서 가중치를 부여하여 시설물별 중요도평가시스템을 개발하였다. 이러한 시설물의 중요도는 시설물을 관리하는 지자체 및 시설물관리자로 하여금 평상시에 관리하는 시설물의 우선순위를 제공하고 재난발생등 위급한 시나리오에서 어느 시설물부터 사전에 관리하고 재난이후에 한정된 예산을 어느 시설물부터 투입하여 보수 보강할 것인가에 대한 체계적인 의사결정지원을 지원할 수 있을 것이다.

• 한국정보시스템학회지:정보시스템연구
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• 제28권4호
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• pp.49-64
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• 2019

Purpose The purpose of this paper is to observe the relative priorities of importances among IT services for Smart tourism as well as the relative priorities of importances among ways for developing the IT Services. Design/methodology/approach AHP analysis model was designed with 3 layers in order to recognize the relative importances priorities of IT services and the ways developing the IT services in Smart tourism. The factors in the top layer consist of Pre-trip IT services, During-trip IT services and Post-trip IT services. The lower factors in second layer of the Pre-trip IT services consists of Tourism information search, Online reservation and Price comparison. The lower factors of the During-trip IT services consists of Context recognition, Virtual Reality and Drone Application. The lower factors of the Post-trip IT services consists of Interactive Sharing and Tagging. The factor of third layer, the ways of developing the IT services consist of Company leading, University leading and Industry-University Collaboration. The structural questionnaire based on the AHP analysis model was designed and used to survey experts in IT and tourism areas. The collected data by the question investigation was analyzed by AHP analysis technique. Findings The importance priority of During-trip IT service was highest among in the three type IT services of tourism life cycle. The importance priority of Price comparison service was highest among IT services for Pre-trip. The importance priority of the Context recognition service was highest among IT services for During-trip. The Interactive sharing service was highest among IT services for Post-trip. It would be confirmed for the IT service development ways of Company leading to be suitable for most of the It services, such as Tourism information search, Online reservation, Price comparison, Context recognition, Virtual reality, Drone application, Interactive sharing.

• 한국의류산업학회지
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• 제10권2호
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• pp.191-197
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• 2008

Despite increasing consumption of luxury brands, research about consumption of luxury brands is limited.The purpose of this article is to gain a deeper understanding of important role of intrinsic consumption motivations in consumption of luxury brands. This article investigated the relationships among consumption motivations, conspicuous consumption belief, Product quality belief, and attitude toward consumption of luxury brands using structural equation modeling. The results reveal that, other-oriented consumers were likely to have strong conspicuous consumption belief,whereas consumers with strong self-oriented value tended to place more importance on product quality attribute of luxury brands. Moreover, Consumers who take into account extended-self tended to have strong conspicuous consumption belief while consumer who put more importance on experientialism were more likely to have greater importance on product quality atthbute. And both conspicuous consumption belief and product quality belief influenced positive attitude formation toward luxury brands.

• 유통과학연구
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• 제15권6호
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• pp.5-12
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• 2017

Purpose - This study is to investigate the effects of consumption values of retailers on the importance of store attributes, and to determine the influence on the consumption values of consumers who shop at complex shopping malls on the empirical and functional attributes in those malls as well as on the influence of on/off-line channels. Research design, data, and methodology - With 344 surveyed questionnaires, this study was conducted by using SPSS 22.0 to verify the reliability and validity of the measured variables. Structural equation model (SEM) was employed as a statistical method for the hypotheses test of this study. Results - The results showed that hedonic value has more influence on the importance of empirical attribute than that of functional attribute in shopping malls. In addition, practical value has more influence on functional attributes than empirical properties of shopping malls. However, these relationships showed the difference in on/off-line channels. As for off-line channels, consumers' consumption values were more influential on empirical attributes, while functional attributes were more important in on-line channels Conclusions - This study analyzed the influence on the importance of the consumption values in store attributes, and the effects of each channel with suggesting practical implications.

• 한국컴퓨터정보학회논문지
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• 제21권11호
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• pp.141-149
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• 2016

In a rapidly changing global environment and the massive development in IT technology, Manufacturing SMEs have difficulties in lack of resources and competencies continued to have strong growth potential "Korean Hidden Champion(K Champ)". In order to overcome the difficulties of Manufacturing SMEs, we examined the core competencies using the AHP and proposed the K Champ development strategy. The implications in the academic is as follows: First, the suggestions for development strategy plan was drawn for the K Champ's core competencies with the recognized importance by the CEO or business executives. Secondly, the manufacturing SMEs were broken down by industry structural characteristics variables(sales amounts, industry sectors, business types and delivery methods) and the importance was investigated, analyzed and clarified. This study is intended to develop strategies of Gyeongsangnam-do manufacturing SMEs for K Champ such as German 'Hidden Champion'. We identified the importance of the level of core competencies and the coherent alternative policy direction and practical alternative were proposed. These mean the concrete relationship of core competencies for the K Champ transition and suggest a realistic directional needed for the local manufacturing SMEs in the proposed 'Government's Development Policy for Korean Hidden Champion'.