• Structural Engineering and Mechanics
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• 제52권2호
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• pp.261-274
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• 2014

An accurate finite element (FE) model of a structure is essential for predicting reliably its dynamic characteristics. Such a model is used to predict the effects of structural modifications for dynamic design of the structure. These modifications may be imposed by design alterations for operating reasons. Most of the model updating techniques neglect damping and so these updated models can't be used for accurate prediction of vibration amplitudes. This paper deals with the basic formulation of damped finite element model updating method and its use for structural dynamic modifications. In this damped damped finite element model updating method, damping matrices are updated along with mass and stiffness matrices. The damping matrices are updated by updating the damping coefficients. A case involving actual measured data for the case of F-shaped test structure, which resembles the skeleton of a drilling machine is used to evaluate the effectiveness of damped FE model updating method for accurate prediction of the vibration levels and thus its use for structural dynamic modifications. It can be concluded from the study that damped updated FE model updating can be used for structural dynamic modifications with confidence.

• 한국정밀공학회지
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• 제6권4호
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• pp.126-135
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• 1989

본 연구에서는 공작기계의 동적설계를 합리적이고 효율적으로 수행하기 위하여 부분구조 합성법을 이용하여 부분구조의 감쇠 및 결합부의 특성행렬을 고려한 구조해석이론을 유도하고, 동적성능인 채터안정성 해석을 위하여 3차원 절삭동역학 이론을 사용하였다. 이를 결합하여 공작기계의 동적설계를 위한 전산프로그램 팩케지를 개발하고 국산 NC 선반의 성능개선에 응용하였으며, 부분구조 변경에 따른 전체 성능의 변화를 검토하였다.

• Coupled systems mechanics
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• 제8권2호
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• pp.169-184
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• 2019

This research work presents a study that aims to assess the dynamic structural behaviour and also investigate the human comfort levels of a reinforced concrete building, when subjected to nondeterministic wind dynamic loadings, considering the effect of masonry infills on the global stiffness of the structural model. In general, the masonry fills most of the empty areas within the structural frames of the buildings. Although these masonry infills present structural stiffness, the common practice of engineers is to adopt them as static loads, disregarding the effect of the masonry infills on the global stiffness of the structural system. This way, in this study a numerical model based on sixteen-storey reinforced concrete building with 48 m high and dimensions of $14.20m{\times}15m$ was analysed. This way, static, modal and dynamic analyses were carried out in order to simulate the structural model based on two different strategies: no masonry infills and masonry infills simulated by shell finite elements. In this investigation, the wind action is considered as a nondeterministic process with unstable properties and also random characteristics. The fluctuating parcel of the wind is decomposed into a finite number of harmonic functions proportional to the structure resonant frequency with phase angles randomly determined. The nondeterministic dynamic analysis clearly demonstrates the relevance of a more realistic numerical modelling of the masonry infills, due to the modifications on the global structural stiffness of the building. The maximum displacements and peak accelerations values were reduced when the effect of the masonry infills (structural stiffness) were considered in the dynamic analysis. Finally, it can be concluded that the human comfort evaluation of the sixteen-storey reinforced concrete building can be altered in a favourable way to design.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 춘계학술대회논문집
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• pp.77-81
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• 2003

SDM (Structural Dynamics Modification) is a tool to improve dynamic characteristics of a structure, more specifically of a base structure, by adding or deleting auxiliary (modifying) structures. In this paper, the goal of the optimal SDM is set to maximize the natural frequency of a base plate structure by attaching serially-connected beam stiffeners. The design variables are chosen as positions of the attaching beam stiffeners, where the number of stiffeners is considered as a design space. The problem of non-matching interface nodes between the base plate and beam stiffeners is solved by using localized Lagrange multipliers, which act to glue the two structures with non-matching interface nodes. As fer the cases of non-matching interface nodes problem, the governing equation of motion of a structure can be considered from the viewpoint of a topological modification, which involves the change of the number of structural members and DOFs. Consequently, the eigenpairs of the beam-stiffened plate structure are obtained by using an eigen reanalysis technique of topological modifications. Evolution Strategies (ES), which is a probabilistic population-based optimization technique that mimics the principles from biological evolution in nature, is utilized as a mean for the optimization.

• Smart Structures and Systems
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• 제10권4_5호
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• pp.427-442
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• 2012

An effective approach for updating finite element model is presented which can provide reliable estimates for structural updating parameters from identified operational modal data. On the basis of the dynamic perturbation method, an exact relationship between the perturbation of structural parameters such as stiffness change and the modal properties of the tested structure is developed. An iterative solution procedure is then provided to solve for the structural updating parameters that characterise the modifications of structural parameters at element level, giving optimised solutions in the least squares sense without requiring an optimisation method. A regularization algorithm based on the Tikhonov solution incorporating the generalised cross-validation method is employed to reduce the influence of measurement errors in vibration modal data and then to produce stable and reasonable solutions for the structural updating parameters. The Canton Tower benchmark problem established by the Hong Kong Polytechnic University is employed to demonstrate the effectiveness and applicability of the proposed model updating technique. The results from the benchmark problem studies show that the proposed technique can successfully adjust the reduced finite element model of the structure using only limited number of frequencies identified from the recorded ambient vibration measurements.

• BMB Reports
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• 제48권3호
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• pp.131-138
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• 2015

Cardiac hypertrophy is a form of global remodeling, although the initial step seems to be an adaptation to increased hemodynamic demands. The characteristics of cardiac hypertrophy include the functional reactivation of the arrested fetal gene program, where histone deacetylases (HDACs) are closely linked in the development of the process. To date, mammalian HDACs are divided into four classes: I, II, III, and IV. By structural similarities, class II HDACs are then subdivided into IIa and IIb. Among class I and II HDACs, HDAC2, 4, 5, and 9 have been reported to be involved in hypertrophic responses; HDAC4, 5, and 9 are negative regulators, whereas HDAC2 is a pro-hypertrophic mediator. The molecular function and regulation of class IIa HDACs depend largely on the phosphorylation-mediated cytosolic redistribution, whereas those of HDAC2 take place primarily in the nucleus. In response to stresses, posttranslational modification (PTM) processes, dynamic modifications after the translation of proteins, are involved in the regulation of the activities of those hypertrophy-related HDACs. In this article, we briefly review 1) the activation of HDAC2 in the development of cardiac hypertrophy and 2) the PTM of HDAC2 and its implications in the regulation of HDAC2 activity.

• Structural Engineering and Mechanics
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• 제54권1호
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• pp.55-67
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• 2015

Taking the mid-span/center-point of the structure as the reference point of capturing the maximum dynamic response is very customary in the available literature of the moving load problems. In this article, the absolute maximum dynamic response of an Euler-Bernoulli beam subjected to a moving mass is widely investigated for various boundary conditions of the base beam. The response of the beam is obtained by utilizing a robust numerical method so-called OPSEM (Orthonormal Polynomial Series Expansion Method). It is underlined that the absolute maximum dynamic response of the beam does not necessarily take place at the mid-span of the beam and thus the conventional analysis needs modifications. Therefore, a comprehensive parametric survey of the base beam absolute maximum dynamic response is represented in which the contribution of the velocity and weight of the moving inertial objects are scrutinized and compared to the conventional version (maximum at mid-span).

• 한국자동차공학회논문집
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• 제14권3호
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• pp.164-169
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• 2006

A systematic methodology has been proposed to establish a reliable design of water pump system. A simplified steady-state dynamic model of water pump system has been developed to study the response of water pump system to the dynamic load mainly due to the run-out and unbalance. Design modifications are needed to strengthen the structural integrity of existing designs. Increasing the natural frequency of system is pursued to prevent a resonance from occurring in the engine excitation range. A computational reliability methodology combined with finite element analysis is used to identify the most significant factor affecting the system performance. This method considered influence of design control parameters for the performance of design. By including control factors to the system model in a systematic way, more reliable design is expected.

• 풍력에너지저널
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• 제14권3호
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• pp.91-99
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• 2023

In research conducted on a southwestern Korean offshore meteorological tower, acceleration datasets were gathered over half a year with time-history sensors. To enhance data credibility, a parallel measurement system was used for verification. A model of the tower was configured using beam elements, and with modifications accounting for added stiffness from auxiliary structures. Ground interactions were considered as calibrated springs based on soil layer properties. The tower's dynamic attributes and mass sensitivity were discerned using eigenvalue analysis. The structural natural frequency was consistent, with variations primarily due to new equipment adding approximately 1400 kgs. With free vibration damping assumptions, a damping ratio of roughly 1 % was derived.

• BMB Reports
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• 제57권9호
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• pp.381-387
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• 2024

The nucleus, a highly organized and dynamic organelle, plays a crucial role in regulating cellular processes. During cell differentiation, profound changes occur in gene expression, chromatin organization, and nuclear morphology. This review explores the intricate relationship between nuclear architecture and cellular function, focusing on the roles of the nuclear lamina, nuclear pore complexes (NPCs), sub-nuclear bodies, and the nuclear scaffold. These components collectively maintain nuclear integrity, organize chromatin, and interact with key regulatory factors. The dynamic remodeling of chromatin, its interactions with nuclear structures, and epigenetic modifications work in concert to modulate gene accessibility and ensure precise spatiotemporal control of gene expression. The nuclear lamina stabilizes nuclear shape and is associated with inactive chromatin regions, while NPCs facilitate selective transport. Sub-nuclear bodies contribute to genome organization and gene regulation, often by influencing RNA processing. The nuclear scaffold provides structural support, impacting 3D genome organization, which is crucial for proper gene expression during differentiation. This review underscores the significance of nuclear architecture in regulating gene expression and guiding cell differentiation. Further investigation into nuclear structure and 3D genome organization will deepen our understanding of the mechanisms governing cell fate determination.