• 제목/요약/키워드: structural adhesive

검색결과 316건 처리시간 0.027초

표적항암치료를 위한 겸형적혈구의 응용 및 치료 효과 (Application and therapeutic effects of sickle red blood cells for targeted cancer therapy)

  • 최세운
    • 한국정보통신학회논문지
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    • 제20권12호
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    • pp.2395-2400
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    • 2016
  • 암 환자들을 대상으로 하는 항암치료법은 나노입자, 폴리머 중합체, 지질, 리포솜 등을 치료 전달체로 이용하여 항암치료를 진행하는 방법들이 주로 활발하게 사용되고 있다. 이러한 전달체는 항암 치료제를 직접 암세포로 정확하게 표적 운반하는 정확성, 정확하게 운반한 후 선택적으로 항암치료제를 방출해야하는 유출제어, 다른 일반 세포들을 약물로부터 보호하는 기능 등을 동시에 가지고 있어야 하지만, 대부분 항암약물의 독성에 기인한 부작용이 발생하고 있다. 겸형적혈구는 암세포주변 혈관세포와 멤브레인 표면에 존재하는 리셉터 사이에의 점착성이 존재하며 추가적 생화학처리 없이 암세포 주변에 표적화가 가능함을 보인다. 또한, 암세포 주변의 혈관의 구조적 변화특성은 겸형적혈구의 중합화 반응을 증가시킨다. 따라서 본 논문에서는 겸형적혈구를 이용한 새로운 항암치료법의 효과를 정량적 혈관분석 방법을 통해 제시하고자 한다.

낙엽송 블록접착집성재의 접착 및 휨 강도 성능 (Bending and Bonding Strength Performances of Larix Block-glued Glulam)

  • 이인환;홍순일
    • Journal of the Korean Wood Science and Technology
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    • 제44권3호
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    • pp.315-322
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    • 2016
  • 2개 이상의 보부재 집성재 요소들의 측면접착으로 제작된 "블록접착집성재"는 대단면 목조건축물의 건축부재로 활용 가능한 구조용재다. 블록접착집성재의 측면은 접착제의 종류와 도포량 및 압체압력을 각기 다른 조합으로 접착하여 박리시험과 전단블록시험으로 접착성능을 검토하였다. 실험결과 레조시놀접착제 $500g/m^2$을 도포하고 압체압력 1.5 MPa의 조건으로 제작된 블록접착집성재의 측면접착성능이 가장 양호하였다. 양호한 측면접착조건으로 제작된 블록접착집성재는 동일단면계수의 대조군 집성재와 휨 강도 성능을 비교 검토하였다. 블록접착집성재의 휨 탄성계수는 대조군 집성재와 유사하였으며, 파괴계수는 대조군집성재 보다 27% 향상되었다. 할렬은 대조군집성재 보다 블록접착집성재에서 다량 발생하였으며, 블록접착집성재의 측면접착층에서 계면파괴나 응집파괴는 관찰되지 않았다.

경사진 CFRP로 접합된 시험편에서의 Mode 1 형 파괴역학적 거동에 관한 연구 (An Investigation on the Behavior of Fracture Mechanics as the Type of Mode I at Specimen Bonded with Tapered Carbon Fiber Reinforced Plastic)

  • 이정호;조재웅;전성식
    • Composites Research
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    • 제29권2호
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    • pp.85-89
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    • 2016
  • 본 논문에서는 복합재료 접합부의 파손거동 예측을 하는 데에 있다. CFRP를 TDCB 형태로 가공하고, 형상계수에 따른 Mode 1 정적해석을 수행하였다. 시험편은 2, 2.5, 3, 3.5의 형상계수(m)들을 가진다. 연구결과로서 시편의 접합면이 탈락이 일어나기까지의 변위는 거의 비슷하게 나왔으나 이때의 반력은 형상계수 m = 3.5에서 가장 높게 나타났으며 이 반력은 412 N으로 m = 2와 비교하면 약 14% 개선된 반력을 보여주고 있다. 접착계면의 탈락과 반력에 관한 데이터는 CFRP구조설계와 그 안전설계에 이바지 할 수 있을 것으로 사료된다.

프리프레그 제작용 에폭시 수지.경화제.경화촉진제 혼합비 변화에 따른 FRMLs의 피로거동 특성 (The Mixture Ratio Effect of Epoxy Resin, Curing Agent and Accelerator on the Fatigue Behavior of FRMLs)

  • 송삼홍;김철웅
    • 대한기계학회논문집A
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    • 제25권4호
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    • pp.592-601
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    • 2001
  • Fiber reinforced metal laminates(FRMLs) are new types of hybrid materials. FRMLs consists of high strength metal(Al 5052-H34) and laminated fiber with structural adhesive bond. The mixture ratio effect of epoxy resin$.$curing agent$.$accelerator on the fatigue behavior of FRMLs was investigated in this study. The epoxy, diglycidylether of bisphenol A(DGEBA), was cured by methylene dianiline(MDA) with or without an accelerator(K-54). Eight different kinds of resin mixture ratios were selected for the test ; five kinds of FRMLs(1) and three others of FRMLs(2). The relationship between da/dN and ΔK with variation of resin mixture ratio was studied. FRMLs(1) and FRMLs(2) indicated approximately 2 times and 2.2 times more improved maximum bending strengths in comparison with those of Al 5052-H34. The resin mixture ratio <1:1> in case of FRMLs(1) indicated the maximum fatigue life, while the resin mixture ratio <1:1:0.2> in case of FRMLs(2) indicated the maximum fatigue life. As results, FRMLs(2) turned out to have more effective characteristics on the fatigue properties and the bending strength than those of FRMLs(1).

Planar Type Flexible Piezoelectric Thin Film Energy Harvester Using Laser Lift-off

  • Noh, Myoung-Sub;Kang, Min-Gyu;Yoon, Seok Jin;Kang, Chong-Yun
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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    • pp.489.2-489.2
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    • 2014
  • The planar type flexible piezoelectric energy harvesters (PEH) based on PbZr0.52Ti0.48O3 (PZT) thin films on the flexible substrates are demonstrated to convert mechanical energy to electrical energy. The planar type energy harvesters have been realized, which have an electrode pair on the PZT thin films. The PZT thin films were deposited on double side polished sapphire substrates using conventional RF-magnetron sputtering. The PZT thin films on the sapphire substrates were transferred by PDMS stamp with laser lift-off (LLO) process. KrF excimer laser (wavelength: 248nm) were used for the LLO process. The PDMS stamp was attached to the top of the PZT thin films and the excimer laser induced onto back side of the sapphire substrate to detach the thin films. The detached thin films on the PDMS stamp transferred to adhesive layer coated on the flexible polyimide substrate. Structural properties of the PZT thin films were characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM). To measure piezoelectric power generation characteristics, Au/Cr inter digital electrode (IDE) was formed on the PZT thin films using the e-beam evaporation. The ferroelectric and piezoelectric properties were measured by a ferroelectric test system (Precision Premier-II) and piezoelectric force microscopy (PFM), respectively. The output signals of the flexible PEHs were evaluated by electrometer (6517A, Keithley). In the result, the transferred PZT thin films showed the ferroelectric and piezoelectric characteristics without electrical degradation and the fabricated flexible PEHs generated an AC-type output power electrical energy during periodically bending and releasing motion. We expect that the flexible PEHs based on laser transferred PZT thin film is able to be applied on self-powered electronic devices in wireless sensor networks technologies. Also, it has a lot of potential for high performance flexible piezoelectric energy harvester.

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Exploration of growth mechanism for layer controllable graphene on copper

  • Song, Woo-Seok;Kim, Yoo-Seok;Kim, Soo-Youn;Kim, Sung-Hwan;Jung, Dae-Sung;Jun, Woo-Sung;Jeon, Cheol-Ho;Park, Chong-Yun
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2011년도 제40회 동계학술대회 초록집
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    • pp.490-490
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    • 2011
  • Graphene, hexagonal network of carbon atoms forming a one-atom thick planar sheet, has been emerged as a fascinating material for future nanoelectronics. Huge attention has been captured by its extraordinary electronic properties, such as bipolar conductance, half integer quantum Hall effect at room temperature, ballistic transport over ${\sim}0.4{\mu}m$ length and extremely high carrier mobility at room temperature. Several approaches have been developed to produce graphene, such as micromechanical cleavage of highly ordered pyrolytic graphite using adhesive tape, chemical reduction of exfoliated graphite oxide, epitaxial growth of graphene on SiC and single crystalline metal substrate, and chemical vapor deposition (CVD) synthesis. In particular, direct synthesis of graphene using metal catalytic substrate in CVD process provides a new way to large-scale production of graphene film for realization of graphene-based electronics. In this method, metal catalytic substrates including Ni and Cu have been used for CVD synthesis of graphene. There are two proposed mechanism of graphene synthesis: carbon diffusion and precipitation for graphene synthesized on Ni, and surface adsorption for graphene synthesized on Cu, namely, self-limiting growth mechanism, which can be divided by difference of carbon solubility of the metals. Here we present that large area, uniform, and layer controllable graphene synthesized on Cu catalytic substrate is achieved by acetylene-assisted CVD. The number of graphene layer can be simply controlled by adjusting acetylene injection time, verified by Raman spectroscopy. Structural features and full details of mechanism for the growth of layer controllable graphene on Cu were systematically explored by transmission electron microscopy, atomic force microscopy, and secondary ion mass spectroscopy.

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강판으로 보강된 RC보의 에폭시-콘크리트 계면의 부착특성 (Bonding Properties of Epoxy-Concrete Interface in RC Beams Strengthened by Steel Plate)

  • 박윤제;신동혁;이광명;신현목
    • 콘크리트학회논문집
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    • 제13권3호
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    • pp.221-227
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    • 2001
  • 강판으로 철근콘크리트 보를 휨보강하면 보의 강성과 강도는 현저하게 증가하나 부착면에서의 조기파괴로 인하여 충분한 연성을 발휘하지 못하는 경우가 자주 발생한다. 본 연구에서는 에폭시와 콘크리트 계면에서의 부착파괴 메카니즘을 규명하기 위하여 Mohr-Coulomb 규준을 채택하였으며, 에폭시-콘크리트 계면의 부착특성을 결정하기 위하여 사전단 부착실험, 직접전단 부착실험 및 휨보강 부재실험을 수행하였다. 실험과 수치해석을 통하여 에폭시-콘크리트 계면의 내부마찰각이 45$^{\circ}$ 일 때 점착력은 50 kgf/$\textrm{cm}^2$~70 kgf/$\textrm{cm}^2$을 얻었으며, 이를 강판으로 보강된 RC보의 구조계산에 적용하여 파괴하중을 예측함으로써 보강보의 조기파괴를 효과적으로 방지할 수 있을 것으로 판단된다.

박막증착조건 변화에 따른 $CuInSe_2$ 박막의 특성에 관한 연구 (Characterization of $CuInSe_2$ thin film depending on deposition parameters)

  • 김영준;양현훈;소순열;정운조;박계춘;이진;정해덕
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 추계학술대회 논문집 광주전남지부
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    • pp.119-122
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    • 2006
  • Process variables for manufacturing the $CuInSe_2$ thin film were established in order to clarify optimum conditions for growth of the thin film depending upon process conditions (substrate temperature, sputtering pressure, DC/RF Power), and then by changing a number of vapor deposition conditions and Annealing conditions variously, structural and electrical characteristics were measured. Thereby, optimum process variables were derived. For the manufacture of the $CuInSe_2$, Cu, In and Se were vapor-deposited in the named order. Among them, Cu and In were vapor-deposited by using the sputtering method in consideration of their adhesive force to the substrate, and the DC/RF power was controlled so that the composition of Cu and In might be 1:1, while the surface temperature having an effect on the quality of the thin film was changed from 100[$^{\circ}C$] to 300[$^{\circ}C$] at intervals of 50[$^{\circ}C$].

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기판온도와 열처리 온도에 따른 CuInSe2 박막의 특성분석 (A Study on Properties of CuInSe2 Thin Films by Substrate Temperature and Annealing Temperature)

  • 양현훈;정운조;박계춘
    • 한국전기전자재료학회논문지
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    • 제20권7호
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    • pp.600-605
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    • 2007
  • Process variables for manufacturing the $CuInSe_2$ thin film were established in order to clarify optimum conditions for growth of the thin film depending upon process conditions (substrate temperature, sputtering pressure, DC/RF Power), and then by changing a number of vapor deposition conditions and Annealing conditions variously, structural and electrical characteristics were measured. Thereby, optimum process variables were derived. For the manufacture of the $CuInSe_2$, Cu, In and Se were vapor-deposited in the named order. Among them, Cu and In were vapor-deposited by using the sputtering method in consideration of their adhesive force to the substrate, and the DC/RF power was controlled so that the composition of Cu and In might be 1 : 1, while the surface temperature having an effect on the quality of the thin film was changed from $100^{\circ}C\;to\;300^{\circ}C$ at intervals of $50^{\circ}C$. The diffract fringe of X-ray, which depended upon the substrate temperature and the Annealing temperature of the manufactured $CuInSe_2$ thin film, was investigated. scanning electron microgaphs of represents a case that a sample manufactured at the substrate temperature of $100^{\circ}C$ was thermally treated at $200{\times}350^{\circ}C$. As a result, at $500^{\circ}C$ of the Annealing temperature, their chemical composition was measured in the proportion of 1 : 1 : 2. It could be known that under this condition, the most excellent thin film was formed, compared with the other conditions.

저항 용접을 이용한 금속 샌드위치 판재 접합에 관한 연구 : Part 1 - 공정변수의 선정 (A Study on the Resistance Welding of Metallic Sandwich Panel : Part 1 - Determination of Process Parameters)

  • 이상민;김진범;나석주
    • Journal of Welding and Joining
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    • 제23권6호
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    • pp.49-54
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    • 2005
  • Inner Structured and Bonded(ISB) panel, a kind of metallic sandwich panel, consists of two thin skin plates bonded to a micro-patterned inner structure. Its overall thickness is $1\~3mm$and it has attractive properties such as ultra-lightweight, high efficiency in stiffness-to-weight and strength-to-weight ratio. In many previous studies, resistance welding, brazing and adhesive bonding are studied for joining the panel. However these methods did not consider productivity, but focused on structural characteristics of joined panels, so that the joining process is very complicated and expensive. In this paper, a new joining process with resistance welding is developed. Curved surface electrodes are used to consider the productivity and the stopper is used between electrodes during welding time to maintain the shape of inner structure. Welding time, gap of electrodes and distance between welding points are selected as the process parameters. By measuring the tensile load with respect to the variation of welding time and gap of electrodes, proper welding conditions are studied. Welding time is proper between 1.5-2.5cycle. If welding time is too long, then inner structures are damaged by overheating. Gap of electrode should be shorter than threshold value fur joint strength, when total thickness of inner structure and skin plate is 3.3mm, the threshold distance is 3.0mm.