• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 춘계학술대회논문집
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• pp.97-102
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• 2007

As environmental vibration requirements on precision equipments get more stringent, use of pneumatic vibration isolators becomes more crucial and, hence, their dynamic performance needs to be further improved. Dynamic behavior of those pneumatic vibration isolation tables is very important to both manufacturer and customer as performance specifications. Together with conventional transmissibility, transient response characteristics are another critical performance index especially when movements of components, e.g., x-y tables, of the precision equipments are very dynamic. In this paper, analysis on transient response of a pneumatic vibration isolation table loaded by a mass moving on it is presented. This is a conventional dynamics problem on a rigid body with 6 degree of freedom and a mass with another degree of freedom. How to obtain transient responses of the isolation table is described when the movements of the mass are prescribed relative to the table.

• 한국소음진동공학회논문집
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• 제17권6호
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• pp.515-523
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• 2007

As environmental vibration requirements on precision equipments get more stringent, use of pneumatic vibration isolators becomes more crucial and, hence, their dynamic performance needs to be further improved. Dynamic behavior of those pneumatic vibration Isolation tables is very important to both manufacturer and customer as performance specifications. Together with conventional transmissibility, transient response characteristics are another critical performance index especially when movements of components, e.g., x-y tables, of the precision equipments are very dynamic. In this paper, analysis on transient response of a pneumatic vibration isolation table loaded by a mass moving on it is presented. This is a conventional dynamics problem on a rigid body with 6 degree of freedom and a mass with another degree of freedom. How to obtain transient responses of the isolation table is described when the movements of the mass are prescribed relative to the table.

• 생명과학회지
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• 제17권6호통권86호
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• pp.847-858
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• 2007

ER-Golgi 분비 경로를 통해서 정확한 구조를 가지면서 post-translational modification 과정을 거친 재조합 단백질의 발현을 최대화하는 것은 ER stress반응에 대한 연구의 중요한 계기가 된다. 세포가 스트레스를 받지 않는 상태라도 ER stress signaling은 재조합 단백질의 생산량을 제한하고 품질을 떨어뜨리는 여러 가지 조건을 만들게 된다. ER stress signaling을 막는 여러 가지 방법들이 제시되고 있으며 표 2는 이러한 방법들 중 일부를 나타내고 있다. 일반적으로는 pro-survival 경로에 관련되어 있는 인자를 촉진하고 pro-apoptosis에 관련되어 있는 인자를 억제하는 것들이다. 그러나 ER stress 반응은 매우 복잡하고 적응과 사멸 기작(adaptation and elimination mechanism)의 중간 역할을 하기 때문에 ER stress에 관련된 주요 인자를 산업적으로 응용하기 위해선 이들의 기능에 대해 보다 깊은 연구가 이루어져야 한다. 현재까지 재조합단백질의 생산량을 최대한으로 높이는 방법은 ER stress 반응이 생기지 않도록 fed-batch process를 개선하고 세포 사멸 기작을 조절하며 단백질의 glycosylation 처리를 하는 것이다.

• Clinical and Experimental Pediatrics
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• 제63권3호
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• pp.104-109
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• 2020

Background: It is challenging to diagnose asthma in preschool children. The asthma predictive index (API) has been used to predict asthma and decide whether to initiate treatment in preschool children. Purpose: This study aimed to investigate the association between questionnaire-based current asthma with API, pulmonary function, airway hyperreactivity (AHR), fractional expiratory nitric oxide (FeNO), and atopic sensitization in preschool children. Methods: We performed a population-based cross-sectional study in 916 preschool children aged 4-6 years. We defined current asthma as the presence of both physician-diagnosed asthma and at least one wheezing episode within the previous 12 months using a modified International Study of Asthma and Allergies in Childhood questionnaire. Clinical and laboratory parameters were compared between groups according to the presence of current asthma. Results: The prevalence of current asthma was 3.9% in the study population. Children with current asthma showed a higher rate of positive bronchodilator response and loose and stringent API scores than children without current asthma. The stringent API was associated with current asthma with 72.2% sensitivity and 82.0% specificity. The diagnostic accuracy of the stringent API for current asthma was 0.771. However, no intergroup differences in spirometry results, methacholine provocation test results, FeNO level, or atopic sensitization rate were observed. Conclusion: The questionnaire-based diagnosis of current asthma is associated with API, but not with spirometry, AHR, FeNO, or atopic sensitization in preschool children.

• International Journal of Automotive Technology
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• 제7권4호
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• pp.407-413
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• 2006

The liquefied petroleum gas(LPG), mixture of propane and butane, has the potential to reduce toxic hydrocarbon emissions and inhibit ozone formation due to its chemical composition. Conventional mixer systems, however, have problems in meeting the future lower emission standards because of the difficulty in controlling air-fuel ratio precisely according to mileage tar accumulation. Liquid Phase LPG injection(LPLi) system has several advantages in more precise fuel metering and higher engine performance than those of the conventional mixer type. On the other hands, leakage problem of LPLi system at the injector tip is a main obstacle for meeting more stringent future emission regulations because these phenomena might cause excessive amount of THC emission during cold and hot restart phase. The main focus of this paper is the development of a leaked fuel recirculation system, which can eliminate the leaked fuel at the intake system with the activated carbon canister. Leaked fuel level was evaluated by using a fast response THC analyzer and gas chromatography. The result shows that THC concentration during cold and hot restart stage decreases by over 60%, and recirculation system is an effective method to meet the SULEV standard of the LPLi engine.

• 소음진동
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• 제5권3호
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• pp.413-421
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• 1995

냉난방용 회전기기에 의한 방사광가속기 건물의 진동은 내부에 설치되어 있는 광학장치나 전자장비의 성능에 영향을 미치기 때문에 건설단계에서 부터 건물 진동에 대한 평가가 매우 중요하다. 본 연구에서는 방사광가속기 건물의 진동을 평가 하기 위해서 실험적 모우드해석법을 이용하여 냉난방기기가 위치한 바닥의 동적특성 을 구하고, 하중응답 모사법을 통해 진동응답치를 계산하였다. 평가결과, 건물바닥의 진동치는 기준치를 상회하고 있으며 이를 해결하기 위해 이중방진 시스템을 설계 제작하여 냉난방기기와 바닥 사이에 설치함으로써 바닥의 진동을 허용한도 이내로 감소시켰다.

• 한국자동차공학회논문집
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• 제13권2호
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• pp.93-100
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• 2005

Stringent emission regulations and increasing demands on reductions of noise and vibration of common rail direct injection (CRDI) diesel engines lead to the advent of piezo-actuated injectors. Compared with solenoid-actuated injectors, piezo-actuated injectors generate greater force and give faster response time, resulting in more accurate and faster injections. The accurate and fast response of an injector can offer an opportunity to control the combustion process and pollutant formation. In this study, the mathematical model of a piezo-actuated injector is developed. An estimator of the injection rate of the piezo-actuated injector is designed based on this model. The sliding mode theory is applied to the estimator design in order to overcome model uncertainties. The injector model and the estimator are verified by the injection experiments in an injector test bench. The simulation and the experimental results show that the proposed sliding mode observer can effectively estimate the injection timing and the injection rate of the piezo-actuated injector.

• ETRI Journal
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• 제30권5호
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• pp.729-734
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• 2008

Wireless communication systems, such as WLAN or Bluetooth receivers, employ preamble data to estimate the channel characteristics, introducing stringent settling-time constraints. This makes the use of traditional closed-loop feedback automatic gain control (AGC) circuits impractical for these applications. In this paper, a compact feedforward AGC circuit is proposed to obtain a fast-settling response. The AGC has been implemented in a 0.35 ${\mu}m$ standard CMOS technology. Supplied at 1.8 V, it operates with a power consumption of 1.6 mW at frequencies as high as 100 MHz, while its gain ranges from 0 dB to 21 dB in 3 dB steps through a digital word. The settling time of the circuit is below 0.25 ${\mu}s$.

• Journal of Ecology and Environment
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• 제36권1호
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• pp.89-94
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• 2013

Diatoms have become an integral part of the UK's freshwater monitoring strategy over the past two decades, mostly in response to increasingly stringent European Union (EU) legislation. The use of diatoms is based on strong correlations between diatom assemblages and environmental variables, and from knowledge of the "expected" (= "reference") state of each river. The nationwide overview of the ecological health of rivers this gives allows those stretches of rivers which fail to meet EU criteria to be identified. This, in turn, allows appropriate remediation measures to be planned. Because diatom assemblages vary in space and time, even within a single water body, effective use of diatoms requires a consistent approach in order to minimise uncertainty. This includes the use of methods which comply with European Standards, a training and accreditation scheme for analysts, and a suite of quality assurance methods. Those aspects of uncertainty that cannot be readily controlled have been quantified and all estimates of ecological status are accompanied by the appropriate "confidence of class" and "risk of misclassification". This, in turn, helps planners prioritise those locations which are most likely to benefit from remediation.

• 한국공작기계학회논문집
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• 제10권5호
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• pp.96-103
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• 2001

The quality requirements for thickness accuracy in cold rolling continue to become more stringent, particularly in response to exacting design specification from automotive customers. One of the major impacts from the tighter tolerance level is more unusable product on the head end and tail end of tandem mill coils when the mill is in transition to or from steady state rolling condition. A strip thickness control system for a tandem cold steel rolling mills is composed with blocked non-interacting controller and controllers for strip thickness and tension control of each rolling stands. An intelligent mathematical model included an elastic deformation of strip has been developed and applied to the field in order to predict the rolling force. The simulated results showed that the effect of elastic recovery should be included the model, even if the effect of elastic compression was not important.