• 대한한방내과학회지
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• 제25권3호
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• pp.590-595
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• 2004

Conversion Disorder is a disorder whose predominant feature is a loss or alteration in physical functioning that suggests a physical disorder but that is actually a direct expression of a psychological conflict or need. The Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) guidelines for Conversion Disorder include these definitions: A psychosocial stressor produces a psychological conflict that is believed to help initiate or exacerbate the illness The symptoms are not under conscious control, etc. While functional disabilities are common with conversion disorders, physical and laboratory abnormalities are absent or minor in comparison with the patient's subjective complaints. Symptoms of Conversion Disorder are similar to those of stroke. But the mechanism of Conversion Disorder is similar as that of Stagnation Syndrome of Ki (氣鬱證) in Oriental medicine. Gaegyeolseogyeong-tang has been used to treat women who suffer from Conversion Disorder induced by the Stagnation Syndrome of Ki (氣鬱證). After application of the Gaegyeolseogyeong-tang for 7 days, symptoms and signs improved dramatically.

• 한국화재소방학회논문지
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• 제24권6호
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• pp.133-138
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• 2010

본 연구는 소방대원의 직무 관련 스트레스, 문제해결양식과 심리적 디스트레스의 관계를 검증하고 직무관련 스트레스, 문제해결양식이 심리적 디스트레스에 미치는 영향을 살펴보고자 하였다. 이를 위해 소방대원의 스트레스의 심각도를 측정하는 스트레스 척도, 문제해결양식 척도 그리고 정신진단척도를 사용하여 스트레스의 양상, 문제해결양식과 심리적 디스트레스 간의 상관분석 및 회귀분석을 시행하였다. 상관분석 결과, 두 가지 직무 관련 스트레스와 심리적 디스트레스가 정적인 상관을 보이며, 문제해결양식의 무기력감과 문제에 대한 통제감이 심리적 디스트레스와 정적인 상관관계를 나타내고, 문제해결에 대한 자신감과 접근적 문제해결양식은 심리적 디스트레스와 부적인 상관관계를 보였다. 직무관련 스트레스와 문제해결양식이 심리적 디스트레스를 예측하는 정도를 파악하기 위해 시행한 중다회귀 분석결과, 직무 관련 스트레스 중에 부정적 인지와 정서, 문제해결양식 중에는 무기력감과 접근적 문제해결양식이 심리적 디스트레스에 유의한 영향을 끼치는 것으로 나타났다. 문제해결양식 중 무기력감이 심리적 디스트레스를 가장 크게 예측하였는데, 이는 직면한 문제를 효율적으로 해결하지 못한 것에 대한 자책과 함께 직업적 자존감(selfesteem)까지 저하시켜, 효율적인 직무수행에 부정적인 영향을 줄 수 있다.

• 한국컴퓨터정보학회논문지
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• 제19권12호
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• pp.275-285
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• 2014

정보통신기술들(information and communication technology: ICT)의 진화는 우리의 의사소통과 커뮤니케이션 문화를 변모시키며 사이버커뮤니케이션 시대로의 촉진을 유인하고 있다. ICT 발달에 따라 '퍼스널'하면서도 사회적 연결과 소통을 강화시킨 '소셜'의 융합이 촉진되고 있으며, 그 중심에 소셜네트워크서비스(social network service: SNS)가 있다. SNS는 개방성, 확장성, 실시간성 등과 같은 발달된 기술을 배경으로 우리생활에 중요한 영역으로 자리매김하고 있지만, 예기치 못했던 부작용으로 사회적 우려를 낳고 있다. 이에 본 연구에서는 SNS스트레스를 발생시키는 요인인 스트레서(stressor)를 파악하고 사용중단의도에 미치는 영향을 실증하는 것을 주요목적으로 하였다. 연구결과, '정보과부하', '사생활침해', '사용불안', '사용복잡', '빠른 변화속도'가 SNS스트레스 영향요인으로 나타났다. 그리고 SNS스트레스는 사용중단의도에 유의한 영향을 미치는 것으로 확인되었다. 본 연구는 개인적 차원의 테크노스트레스 및 SNS사용중단의도에 관한 논의를 확장시키고 실무적 가이드라인을 제공한다는 점에서 의의를 찾을 수 있다.

• Journal of Ginseng Research
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• 제34권2호
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• pp.138-144
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• 2010

Ginseng (Panax ginseng C.A. Meyer) has been shown to have anti-stress effects in animal studies. However, most studies have only managed to detect altered levels of biomarkers or enzymes in blood or tissue, and the actual molecular mechanisms by which ginseng exerts these effects remain unknown. In this study, the anti-oxidative effect of Korean red ginseng (KRG) was examined in human SK-N-SH neuroblastoma cells. Incubation of SK-N-SH cells with the oxidative stressor hydrogen peroxide resulted in significant induction of cell death. In contrast, pre-treatment of cells with KRG decreased cell death significantly. To elucidate underlying mechanisms by which KRG inhibited cell death, the expression of apoptosis-related proteins was examined by Western blot analysis. KRG pre-treatment decreased the expression of the pro-apoptotic gene caspase-3, whereas it increased expression of the anti-apoptotic gene Bcl-2. Consistent with this, immunoblot analysis showed that pre-treatment of the SK-N-SH cells with KRG inhibited expression of the pro-inflammatory gene cyclooxygenase 2 (COX-2). RT-PCR analysis revealed that the repression of COX-2 expression by KRG pre-treatment occurred at the mRNA level. Taken together, our data indicate that KRG can protect against oxidative stress-induced neuronal cell death by repressing genes that mediate apoptosis and inflammation.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.552-565
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• 2016

본 연구는 물질적 어려움과 음주의 관계에서 자아존중감과 가족갈등 요인의 구조적 관계를 검증하는데 목적이 있다. 한국복지패널 최신 3개년도(2012-2014) 자료를 사용하여 가구균등화 소득의 중위소득 60%를 기준으로 저소득가구를 선정하였고, 이중 단독가구를 제외한 960명의 가구주 자료를 분석에 활용하였다. 주요 변수는 물질적 어려움, 음주행위, 자아존중감, 가족갈등이고, 이 변수들 사이의 구조적 관계를 검증하기 위해 경로분석을 사용하였다. 물질적 어려움은 음주에 직접효과를 갖지 않았지만, 가족갈등과 자아존중감을 매개로 하는 간접효과를 보여주었다. 즉, 물질적 어려움을 경험하는 것은 부정적 가족갈등 대처방법, 낮은 자아존중감과 유의미한 관계를 보여주었다. 그리고 긍정적 가족갈등 대처방법과 낮은 자아존중감은 낮은 음주행위와 유의미한 관계를 보여주었다. 이러한 결과는 저소득층이 경험하는 물질적 어려움, 가족갈등, 자아존중감이 문제음주의 결과로 이어질 가능성을 보여주고 있어 이에 대한 실천적 정책적 대응이 필요함을 시사한다.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.27-27
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• 2003

Lake Texoma is located on the border of southern Oklahoma and northern Texas. It has 93,000 surface acres, and is a focus of the recreation, and farming industries in the region. There are potential stressors around the Lake Texoma watershed that may cause adverse ecological effects in the lake. System assimilative capacity (SAC) is the ability of abiotic and biotic processes to atteuniate the stressors. SAC Exceeded indicates potential of occuring adverse eco-effects. A number of representative chemical release sites and stressor sources in the surrounding watershed were characterized, and several impact sites having stressors sources, such as being near agriculture, landfills, housing areas, oil production fields and heavy use recreational activity, were selected for surface water, sediment, and groundwater monitoring. A paired reference site, having similar physical characteristics as its impact site, was also chosen based on its proximity to the impact site. Lake water samples were collected at locations identified as marina entrance, gasoline filling station, and boat dock at five marinas selected on Lake Texoma from September 1999 to December 2001. Paired water and sediment samples were also collected. Groundwater samples were collected at about 70 producing monitoring wells. Water quality parameters measured were inorganics (nitrate, nitrite, orthophosphate, ammonia, sulfate, and chloride), dissolved methane, total organic carbon (TOC) (or DOC), volatile organic compounds (VOCs) such as methyl tert-butyl ether (MTBE) and BTEX, and a suite of metals. Biotic communities were evaluated at impact and reference sites. Five basic components were measured; two terrestirial components (plants and bird comminitires) and three aquatic components (benthic inverbrates, litteral-zone fishes, ecosystem attribures). Potential impacts to these comminites were evaluated.

• Journal of Microbiology and Biotechnology
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• 제14권2호
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• pp.243-249
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• 2004

The toxicity of inorganic sulfuric acid as a stressor was characterized in Saccharomyces cerevisiae KNU5377. In this work, we examined physiological responses to low extracellular pH $(pH_{ex})$ caused by inorganic $H_2SO_4$, which could not affect cell growth after pH was adjusted to an optimum with Trizma base. The major toxicity of sulfuric and was found to be reduction of environmental pH, resulting in stimulation of plasma membrane ${H^+}-ATPase$, which in turn contributed to intracellular alkalinization. Using a pH-dependent fluorescence probe, 5-(and-6)-carboxy SNARF-1, acetoxymethyl ester, acetate (carboxy SNARF-1 AM acetate), to determine $pH_{in}$, we found that color was dependent on the changes of intracellular pH which coincided with calculated $pH_{in}$ of alkalinization up to approximately pH 7.3. This alkalinization did not seem to affect survival of these cells exposed to 30 mM sulfuric acid, which lowered the $pH_{ex}$ of the glucose containing growth media up to approximately pH 3.0; however, the cells could grow only up to 70% of the maximum growth in the same media, when 30 mM sulfuric acid was added.

• 동의신경정신과학회지
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• 제12궈1호
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• pp.3-10
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• 2001

Psychology and esters medicine are congenital therapeutic partners. they are closer in concept and practice to each other than either is to the principles of western science and medicine. Estern medicine, like most psychotherapies, is concerned with an individual's unique physical and emotional state. The aim of this study is to review Ii-Geug-Byun-Qi(移精變氣療法) therapy which is one of the psychotherapies in estern medicine. We studied few representative books which are about in estern medicine and also studied some clinical case reports on psychotherapies by estern medicine therapy, specially about Ii-Geug-Byun-Qi(移精變氣療法) therapy. Generally we understood Chukyoo(祝由) is the eldest psychological therapy which is based on Shamanism and controlled by Shaman as a doctor. and it is similar to simple psychoanalysis in western medicine. The psychologic therapy of Ii-Geug-Byun-Qi (移精變氣療法) is typical estem medicine psychologic therapy since the principle of estern medice had built like Hwang-Chi-Nei-Ching(黃帝內經). The meaning. of Ii-Geug-Byun-Qi(移精變氣療法) therapy is holistic psychologic therapy which are based on the harmony of mind and body. The practical method of Ii-Geug-Byun-Qi(移精變氣療法) are to refresh patient's emotional condition, like ventilaltion. The second healing method of Ii-Geug-Byun-Qi(移精變氣療法) is persuasion by dialogue. The third method is to clear patient's doubt by explainning of some qutestions. Therefore, the indication of Ii-Geug-Byun-Qi(移精變氣療法) therapy are psychosomatic disease or psychogenic problems. In conclusion, I suggest that the Ii-Geug-Byun-Qi(移精變氣療法) therapy could be powerfully adopt to prevent or treat lots of disease which is related with mind and body induced by stressor.

• The Journal of Korean Physical Therapy
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• 제21권2호
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• pp.109-116
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• 2009

Purpose: $17\beta$-estradiol is the most active endogenous estrogen, which is related to favorable changes in the plasma lipid profile, to relaxation of the coronary vessels, and to a decrease in platelet aggregation and vascular smooth muscle cell migration. However, although the beneficial effect of estrogens on plasma lipoproteins (ie, lowering low-density lipoprotein and increasing high-density lipoprotein cholesterol) contributes to cardiovascular protection, it does not fully account for the protective effect, particularly in the application of physical therapy, including low frequency electrical stimulation. Methods: The aim of this study was to demonstrate the inhibition of stressors, such as endothelin-1 (ET-1), serotonin (5-hydroxytryptamine, 5-HT), prostaglandin $F2\alpha$ ($PGF2\alpha$), and a protein kinase C (PKC) activator 12-deoxyphorbol 13-isobutyrate (DPB), induced isometric tension by $17\beta$-estradiol in vascular smooth muscle strips, respectively. In addition, the effects of low frequency electrical stimulation at the meridian points (CV-3, -4, Ki-12, SP-6, LR-3, BL-25, -28, -32, -52) on the indirect antihypertensive effect were examined by monitoring the changes in the serum $17\beta$-estradiol concentration in healthy volunteers. Results: Isometric tension analysis showed that the responses of inhibited tension by $17\beta$-estradiol were similar to the same stressors in rat aortic smooth muscle strips. Furthermore, although the continued amplitude modulation (AM) type of electrical stimulation was not increased significantly by electrical stimulation, the current of the frequency modulation (FM) type of low frequency electrical stimulation increased the serum $17\beta$-estradiol concentration in normal volunteers. Conclusion: These results, in part, suggest that $17\beta$-estradiol has the capacity to supress stressor-induced muscle tension, and electrical stimulation, particularly current of the FM type, has a modulatory effect on the sex steroid hormones, particularly $17\beta$-estradiol, in healthy volunteers.

• 대한불안의학회지
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• 제10권1호
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• pp.3-10
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• 2014

Reactive disorder is a group of diagnosis with a definitely known etiology and whose etiological factor is essential to the diagnosis. In DSM system, such reactive disorders are listed as adjustment disorder, acute stress disorder, brief psychotic disorder with marked stressor and posttraumatic stress disorder (PTSD). However, a growing number of individuals is suffering from a prolonged feeling of embitterment after exceptional negative life events and this condition could be diagnosed neither PTSD nor adjustment disorder nor depressive disorder in the context of DSM-IV diagnostic system. This clinical condition can be described as 'posttraumatic embitterment disorder' (PTED). PTED is a reactive disorder triggered by exceptional, though normal negative life events such as conflict in the workplace, unemployment, death of a relative, divorce, severe illness, or experience of loss or separation. The common feature of such events is that they are experienced as unjust, as a personal insult, accompanied by psychological violation of basic beliefs and values. The central psychopathological response pattern in PTED is a prolonged feeling of embitterment. In particular, the core emotion of embitterment can lead to the rejection of treatment. Therefore, "wisdom therapy" as a new treatment approach specifically designed for PTED has been developed. It is assumed that many patients suffering from PTED are often misunderstood and misdiagnosed. This review would help to introduce PTED into the clinical field in psychiatry.