The development of a city is closely linked to the construction and operation of its subway system. However, constructing a new subway tunnel under an existing station is an extremely complex task, and the deformation characteristics and mechanical behavior of the new subway tunnel during the excavation process can greatly impact the normal operation of the existing station. Although the previous studies about the case of underpass engineering have been carried out, there is limited research on the condition of a newly-built subway tunnel that closely undercrossing an existing station with zero distance between them. Therefore, this study analyzes the deformation law and mechanical behavior characteristics of the preliminary lining of the underpass tunnel during the excavation process based on the real engineering case of Chengdu Metro Line 8. This study also makes an in-depth comparison of the influence of different excavation methods on this issue. Finally, the accuracy of numerical simulation is verified by comparing it with on-site result. The results indicate that the maximum bending moment mainly occurs at the floor slab of the preliminary lining, while that of the ceiling is small. The stress state at the ceiling position is less affected by the construction process of the pilot tunnel. Compared to the all-in-one excavation method, although the process of partial excavation method is more complicated, the deformation of preliminary lining caused by it is basically less than the upper limit value of the standard, while that of the all-in-one excavation method is beyond standard requirements.
Objectives : This study evaluates how various traditional Korean herbal medicines assess MUC5AC expression for esophageal mucosal defense and analyzes the associated mechanisms involved in inflammation. Methods : Forty types of traditional Korean herbal medicines were assessed for in vitro antioxidant activities, and the real-time PCR method was employed to analyze MUC5AC expression under pH 4.5 conditions in human esophageal epithelial cells (HET-1A). Eight types of Korean herbal medicines were evaluated for in vitro antioxidant activities, and Reactive oxygen specise (ROS) expression was analyzed under bile salt (480 𝜇M) and pH 5.5 conditions in human esophageal epithelial cells (HET-1A). Simulation experiments involving bile salts and acidity were conducted for one hour to assess the efficacy of four drugs, and the activities of Mitogen-activated Protein Kinase (MEK), Nuclear Factor Kappa B (NF-𝜅B), and Cyclooxygenase-2 (COX-2) were detected through Western blot analysis. Results : Compared to the Normal group, the Control group exhibited higher ROS generation. Such increased ROS levels were significantly reduced by four extracts: Citrus Unshius Pericarpium (CUP), Cnidium officinale Rhizoma (CR), Ginseng Radix (GR), and Linderae Radix (LR). The protein expression of COX-2 decreased with the treatment of LR, CUP, and CR. Particularly, CUP and CR exhibited superior effects compared to other groups in inhibiting the phosphorylation of NF-𝜅B. Conclusion : Based on the results obtained, we have identified drugs that inhibit oxidative stress and inflammation caused by bile acid in esophageal epithelial cells. Our future plans involve comparing and analyzing the efficacy of these herbal medicines through animal experiments.
Hyeon-Woo Kang;Jung-Hoe Kim;Young-Ki Cho;Won-Seok Choi;Hyun-Ji Lee;Hun-Kee Kim
The Journal of the Korea institute of electronic communication sciences
/
v.19
no.3
/
pp.589-602
/
2024
Thermoelectric generator (TEG) generally do not have high heat conversion efficiencies. The performance of a thermoelectric generator module depends on the shape of the legs as well as the properties of the material and the number of legs. In this study, the leg shapes of thermoelectric elements are modeled into various geometric structures such as cylinder and cube shaped to efficiently harvest waste heat, and the electrical characteristics are compared numerically. The temperature gradient and power generation according to the bridge shape are found to be highest at the existing Cube shape. As a result of comparing the power generation using the cooling effect, the Cone shape was the highest in natural convection and the Hourglass shape was highest in forced convection. Research results confirm that geometry can affect the efficiency of thermoelectric generators.
Ning Jiao;Xing Wan;Jianwen Ding;Sai Zhang;Jinyu Liu
Geomechanics and Engineering
/
v.36
no.2
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pp.131-143
/
2024
Shield tunneling construction commonly crosses underground pipelines in urban areas, resulting in soil loss and followed deformation of grounds and pipelines nearby, which may threaten the safe operation of shield tunneling. This paper investigated the pipeline deformation caused by double curved shield tunnels in soil-rock composite stratum in Nanjing, China. The stratum settlement equation was modified to consider the double shield tunneling. Moreover, a three dimensional finite element model was established to explore the effects of hard-layer ratio, tunnel curvature radius, pipeline buried depth and other influencing factors. The results indicate the subsequent shield tunnel would cause secondary disturbance to the soil around the preceding tunnel, resulting in increased pipeline and ground surface settlement above the preceding tunnel. The settlement and stress of the pipeline increased gradually as buried depth of the pipeline increased or the hard-layer ratio (the ratio of hard-rock layer thickness to shield tunnel diameter within the range of the tunnel face) decreased. The modified settlement calculation equation was consistent with the measured data, which can be applied to the settlement calculation of ground surface and pipeline settlement. The modified coefficients a and b ranged from 0.45 to 0.95 and 0.90 to 1.25, respectively. Moreover, the hard-layer ratio had the most significant influence on the pipeline settlement, but the tunnel curvature radius and the included angle between pipeline and tunnel axis played a dominant role in the scope of the pipeline settlement deformation.
Han Xiao;Wei Wang;Chen Xu;Sheraz Abbas;Zhiping Lin
Steel and Composite Structures
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v.50
no.6
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pp.659-674
/
2024
Casting Ultra High-Performance Concrete (UHPC) on an orthotropic steel deck and forming a composite action by connectors could improve the steel deck fatigue performance. This study presents the mechanical performance of a proposed post-combination connection between UHPC and steel, which had a low constraint effect on UHPC shrinkage. A total of 10 push-out tests were conducted for static and fatigue performance investigations. And the test results were compared with evaluation methods in codes to verify the latter's applicability. Meanwhile, nonlinear simulation and parametric works with material damage plasticity models were also conducted for the static and fatigue failure mechanism understanding. The static and fatigue test results both showed that fractures at stud roots and surrounding local UHPC crushes were the main failure appearances. Compared with normally arranged studs, group arrangement could result in reductions of static stud shear stiffness, strength, and fatigue lives, which were about 18%, 12%, and 27%, respectively. Compared with the test results, stud shear capacity and fatigue lives evaluations based on the codes of AASHTO, Eurocode 4, JSCE and JTG D64 could be applicable in general while the safety redundancies tended to be smaller or even insufficient for group studs. The analysis results showed that arranging studs in groups caused obviously uneven strain distributions. The severer stress concentration and larger strain ranges caused the static and fatigue performance degradations of group studs. The research outcome provides a very important basis for establishing a design method of connections in the novel post-combination steel-UHPC composite deck.
Zakaria Belabed;Abdeldjebbar Tounsi;Abdelmoumen Anis Bousahla;Abdelouahed Tounsi;Mohamed Bourada;Mohammed A. Al-Osta
Structural Engineering and Mechanics
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v.90
no.3
/
pp.233-252
/
2024
This research explores a new finite element model for the free vibration analysis of bi-directional functionally graded (BDFG) beams. The model is based on an efficient higher-order shear deformation beam theory that incorporates a trigonometric warping function for both transverse shear deformation and stress to guarantee traction-free boundary conditions without the necessity of shear correction factors. The proposed two-node beam element has three degrees of freedom per node, and the inter-element continuity is retained using both C1 and C0 continuities for kinematics variables. In addition, the mechanical properties of the (BDFG) beam vary gradually and smoothly in both the in-plane and out-of-plane beam's directions according to an exponential power-law distribution. The highly elevated performance of the developed model is shown by comparing it to conceptual frameworks and solution procedures. Detailed numerical investigations are also conducted to examine the impact of boundary conditions, the bi-directional gradient indices, and the slenderness ratio on the free vibration response of BDFG beams. The suggested finite element beam model is an excellent potential tool for the design and the mechanical behavior estimation of BDFG structures.
Park, Kyong-Ok;Ahn, Young-Mee;Kang, Na-Rae;Lee, Mi-Jin;Sohn, Min
Child Health Nursing Research
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v.19
no.2
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pp.85-93
/
2013
Purpose: The study purposes were to describe the process of developing the Korean versions of the Six Dimension Scale of Nursing Performance (Six-D) and Student Nurse Stress Index (SNSI) and psychometric evaluation of the two measurements. Methods: This was a methodology study using a descriptive cross-sectional design with 51 nursing students in 4th year of university. Internal consistency reliability was assessed using Cronbach alphas. Construct validity was determined by exploring correlations among Six-D, SNSI, objective structured clinical examination (OSCE), self-efficacy and grade point average (GPA). Results: Internal consistency reliability of Six-D and SNSI was acceptable with Cronbach's ${\alpha}$ of .95 and .82. Correlation analysis to determine construct validity revealed that Six-D presented positive correlations with OSCE (r=.109~.272) and self-efficacy (r=.005~.161) and negative correlation with GPA (r=-.246~-.394), although all were not statistically significant. SNSI presented all negative correlations with OSCE (r= -.007~-.238), self-efficacy (r=-.246~-.394), and GPA (r=-.092~-.426) and were mostly statistically significant except OSCE. Conclusion: Six-D needs more evidence to confirm validity to predict observed clinical competency and theoretical relationships with self-efficacy and GPA. However, SNSI presented trends of expected relationships with relevant variables. Therefore, further research is recommended in testing validity of Six-D with other student populations.
Concrete pavement may suffer from material deterioration or structural problems, which lead to surface cracks and deflection of a concrete pavement. Degraded concrete pavement, when it is still under operation, should be recovered by an urgent maintenance to avoid the discontinued service leading to the significant traffic problems and economic loss. Seismic techniques are good tools to assess the structural integrity of concrete runway. It is because seismic techniques can evaluate engineering properties nondestructively and quickly and the evaluation can be extended to subgrade. In this study, a series of numerical simulations of stress-wave propagation were performed to verify feasibility of seismic techniques as an assessment tool. Based on the results of the numerical simulation, a framework of using seismic techniques was presented fur the nondestructive integrated assessment fur structural integrity of concrete runway. And the presented framework was applied to $\bigcirc\bigcirc$ concrete runway with surface cracks, which required urgent maintenance, to identify the causes of the surface cracks. The results obtained from the structural integrity assessment were compared with the measurements of the cores collected from the same runway for verification of the presented framework.
Overpopulation has significantly increased the use of underground spaces in urban areas, and led to the developments of shallow-depth underground space. Due to unexpected rock fall, however, it is very necessary to understand and categorize the rock mass behaviors prior to the tunnel excavation, by which unnecessary casualties and economic loss could be prevented. In case of cave-in, special attention should be drawn since it occurs faster and greater in magnitude compared to rock fall and plastic deformation. Types of cave-in behavior are explained and categorized using seven parameters - Uniaxial Compressive Strength (UCS), Rock Quality Designation (RQD), joint surface condition, in-situ stress condition, ground water condition, earthquake & ground vibration, tunnel span. This study eventually introduces a new index called Cave-in Behavior Index (CBI) which explains the behavior of cave-in under given in-situ conditions expressed by the seven parameters. In order to assess the mutual interactions of the seven parameters and to evaluate the weighting factors for all the interactions, survey data of the experts' opinions and Rock Engineering Systems (RES) were used due to lack of field observations. CBI was applied to the tunnel site of Seoul Metro Line No. 9. UDEC analyses on 288 cases were done and occurrences of cave-in in every simulation were examined. Analyses on the results of 288 cases of simulations revealed that the average CBI for the cases when cave-in for different patterns of tunnel support was estimated by a logistic regression analysis.
Proceedings of the Korean Society of Precision Engineering Conference
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2002.05a
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pp.121-123
/
2002
The design of an air seat cushion for preventing decubitus ulcer includes many design factors such as the even distribution of interface pressure, the minimization of mean and peak interface pressure values, and the reduction of interface shear force and pressure gradient. It involves the anatomic condition of plegia's buttock as well as air pressure in air cells of cushion. As a result, a suitable design of the cushion satisfying the all requirements is a difficult problem. Therefore, an appropriate and effective numerical tool to develop an air cushion orthosis is required. The purpose of the present study was to develop an air seat cushion orthosis having optimized air cells for evenly distributed interface pressure between the buttock and cushion surface. For the purpose, an advanced finite element (FE) model for the design of air cushion was developed. Since the interface pressure and shear force behavior, as well as stress analyses were primary concern, a FE air cell model was developed and verified by the experiments. Then, the interactions of two cells were checked. Also, the human part of the developed numerical model includes every material property and geometry related to buttock and femoral parts. For construction of dimension data of buttock and femoral parts, CT scans were performed. A commercial FE program was employed for the simulation representing the seating process on the orthosis. Then, sensitive analyses were performed with varying design parameters. A set of optimal design parameters was found satisfying the design criteria of the orthosis. The results were utilized to produce a prototype of the orthosis. Experimentally, the buttock interface pressure distributions from the optimized and previous ones were compared. The new seat orthosis showed a significantly improved interface pressure characteristics compared to the most popular one in the market. The new orthosis will be used for the development of the AI(artificial intelligent) controlled seat orthosis fur prevention of decubitus ulcer fur various plegic patients and the elderly.
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