• Journal of dental hygiene science
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• v.12 no.3
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• pp.279-286
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• 2012

The aim of this study was to evaluation the association between obesity and periodontitis according to the characteristics of subjects. The subjects of this study was 429 subjects aged 19 years or older from March to May, 2010. Data were analyzed with chi-square test, Multivariable logistic regression and Statistics were analyzed linear regression analysis using SPSS 18.0. WHR had dose-effect relationship with the number of sextants with periodontitis. With regard to relationships between obesity type and periodontitis depending on characteristics of objects, the WHR obesity group showed results higher than the normal group, for twice(OR: 2.24; 95% CI: 1.17-4.28) and three times or more(OR: 3.34; 95% CI: 1.53-7.27) in frequency of daily teeth brushing, 0-3 points(OR: 2.47; 95% CI: 1.09-5.59) and 4-6 points(OR: 3.99; 95% CI: 1.75-9.08) in the self-perception of stress level, and the group with 8 hours or more(OR: 4.20; 95% CI: 2.11-8.34) in the sleeping time. If anyone is judged to have obesity by WHR, we can say that the risk to have periodontitis together with it is 2.56 times more likely(95% CI: 1.58-4.13).

• Journal of Life Science
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• v.21 no.4
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• pp.529-533
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• 2011

Metallothioneins (MT) are a group of low-molecular weight, cysteine-rich, intracellular proteins that are encoded by a family of genes containing at least 10 functional isoforms in human. The expression and induction of these proteins is associated with protection against DNA damage, oxidative stress, and apoptosis. Many studies have shown increased expression of MT in various human tumors, whereas MT is down-regulated in certain tumors such as hepatocellular carcinoma and liver adenocarcinoma. Hence, the expression of MT is not universal to all human tumors but may depend on the differentiation status and proliferative index of tumors, along with other tissue factors and gene mutations. Using Northern blot analysis, we found that laminin induced expression of MT-1 in HSG and PC12 cells, which can be differentiated by laminin, but had no effect on MB-231, MDA-435, and PC-3 cells, which cannot be differentiated by laminin. In addition, we analyzed the expression level of the MT-1 gene in five prostate cancer cell lines possessing different metastatic potential. The expression of MT-1 in normal and less malignant cells (RWPE-1 and WPE1-NA22) was high and up-regulated by laminin, whereas the expression of MT-1 in WPE1-NB14, WPE1-NB11, and WPE1-NB26 cells (malignant) was extremely low and not elevated by laminin. These results suggest that the MT-1 gene is involved in laminin-mediated differentiation and affects the metastatic potential of tumor cells.

• Research in Community and Public Health Nursing
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• v.14 no.1
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• pp.144-156
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• 2003

This study was conducted to investigate the relationship between the self-esteem, social support and health promoting lifestyle of the elderly in a community. The sample consisted of 147 elderly, and data were collected from September 1 to October 15, 2001. The instrument of this study was a structured questionnaire including Health Promoting Lifestyle (47 items), Social Support(18 items), Self-Esteem(10 items), Socio-demographic Characteristics. Analysis of the data was done by use of descriptive statistics, ANOVA, Pearson Correlation Coefficient. The results of this study are as follows: 1. The degrees of self-esteem of the elderly were mean score $25{\pm}2.98$ points, socio-demographic characteristics containing meaningful difference with self-esteem was not significant. 2. The degrees of social support by elderly were mean score $55.03{\pm}9.60$ points and social support according to the socio-demographic characteristics showed meaning difference in family structure $\ulcorner$with off spring$\lrcorner$ (F=8.50, p=.000), health status $\ulcorner$good$\lrcorner$ (t=2.19, p=.030), smoking $\ulcorner$below 1 packet daily$\lrcorner$ (F=4.88 p=.009). 3. The degrees of health enhancing lifestyle by elderly were mean score $113.61{\pm}20.12$ points and health enhancing lifestyle according to the socio-demographic characteristics showed meaning difference in education level $\ulcorner$middle school and above$\lrcorner$ (F=6.37 p=.002), occupation before retirement $\ulcorner$profession, technician, employee of company, education$\lrcorner$ (F=5.00, p=.003), health status $\ulcorner$good$\lrcorner$ (t=3.14, p=0.002), exercise $\ulcorner$weekly 2-3$\lrcorner$ (F=4.31, p=.006), drinking $\ulcorner$weekly 1$\lrcorner$ (F=2.74, p= .046). 4. The item mean score of personal relationship support field in health enhancing lifestyle were $2.90{\pm}.60$ points. item mean scores of exercise and nutrition were $2.26{\pm}.39$ points, item mean scores of stress managing field were $2.25{\pm}.49$ points, item mean scores of health responsible field were $2.14{\pm}.61$ points. 5. The relationship between self-esteem and health enhancing lifestyle revealed a significant correlation(r=.169. p=.041), but self-esteem and social support, showed no significant correlation, and health enhancing lifestyle and social support, revealed a significant correlation(r=.654, p=.001).

• Structural Engineering and Mechanics
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• v.31 no.2
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• pp.181-210
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• 2009

This paper presents the theoretical developments of an exact finite strip for the buckling and initial post-buckling analyses of isotropic flat plates. The so-called exact finite strip is assumed to be simply supported out-of-plane at the loaded ends. The strip is developed based on the concept that it is effectively a plate. The present method, which is designated by the name Full-analytical Finite Strip Method in this paper, provides an efficient and extremely accurate buckling solution. In the development process, the Von-Karman's equilibrium equation is solved exactly to obtain the buckling loads and the corresponding form of out-of-plane buckling deflection modes. The investigation of thin flat plate buckling behavior is then extended to an initial post-buckling study with the assumption that the deflected form immediately after the buckling is the same as that obtained for the buckling. It is noted that in the present method, only one of the calculated out-of-plane buckling deflection modes, corresponding to the lowest buckling load, i.e., the first mode is used for the initial post-buckling study. Thus, the postbuckling study is effectively a single-term analysis, which is attempted by utilizing the so-called semi-energy method. In this method, the Von-Karman's compatibility equation governing the behavior of isotropic flat plates is used together with a consideration of the total strain energy of the plate. Through the solution of the compatibility equation, the in-plane displacement functions which are themselves related to the Airy stress function are developed in terms of the unknown coefficient in the assumed out-of-plane deflection function. These in-plane and out-of-plane deflected functions are then substituted in the total strain energy expressions and the theorem of minimum total potential energy is applied to solve for the unknown coefficient. The developed method is subsequently applied to analyze the initial postbuckling behavior of some representative thin flat plates for which the results are also obtained through the application of a semi-analytical finite strip method. Through the comparison of the results and the appropriate discussion, the knowledge of the level of capability of the developed method is significantly promoted.

• Korean Journal of Occupational Health Nursing
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• v.13 no.2
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• pp.104-117
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• 2004

Objectives: To propose the basic data for the development of the optimum health promotion program (HPP) for the workers in a petrochemical industry complex. Methods: The subjects were 553 workers who worked at the six plants in a petrochemical industry complex. From February to March 2003, questionnaire survey was conducted by the nurses with occupational health specialty about the life styles, interests, self-cognitions, practices of health behavior, subjective symptoms thought to be related the working environments, burden to the own health, needs and intentions to participation of the HPP. Data analysis was done using SPSS program (ver 10.0) with ${\alpha}=0.05$ of statistical significance. Results: The mean age and tenure of the subjects were 39.7 years and 14.2 years, respectively, and proportion of smokers was around 50%. Two of third (66%) satisfied their own job, and 58% recognized themselves healthy. The most frequent health behavior were exercise (60%) and regular health check (87%) in individual and job based, respectively. About half of them (58%) had at least one of the symptoms thought to be related the working environments, and the most frequent one was odor (21%). These symptoms were more frequent in case of the shorter career. The needs of HPP was relatively higher in exercise (66%), cancer prevention (51%), stress control (47%), and intention to participation was also the highest in exercise (64%). Job satisfaction was higher in case of the higher interests and cognitions to their own health, and thought that the ownership's interest to workers' health be high (p<0.01), but no associations with the subjective symptoms. The mean level of burden to the own health were $14.1{\pm}13.9$ of physical, $11.7{\pm}13.6$ of emotional, $9.1{\pm}10.7$ of behavioral as out of one hundred. They felt the more burden in case of office workers, the lower interests and cognitions to their own health, the lower satisfaction to their job, the frequent drinking group, and complained the subjective symptoms (p<0.05). Abnormal results of the regular health check was higher in the frequent drinking group (p=0.083). Conclusions: For the optimum HPP for the workers in the petrochemical complex, the ownership's interest to workers' health would be enhanced, and the priority would be focused on exercise and drinking habits control.

• Journal of Environmental Health Sciences
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• v.31 no.4 s.85
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• pp.266-279
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• 2005

The present study was conducted to analyze the causes of stress on the part of Korean radiological technologists depending on their working environments. For this purpose, 890 questionnaires were distributed to and collected from radiological technologists who were working at 44 general hospitals in 16 cities and provinces of Korea during the period from the mid July to the end of August 2003. The collected data were compared between regions, divided into the capital, metropolitan, medium and small cities, whose results are as follows: 1. As factors affecting working conditions, drinking was found to exert more influence on radiological technologists in small- and medium-sized cities, while loyalty to immediate seniors and organizations was the one producing greater influence on them in metropolitan cities than other cities. Overall, position, job satisfaction and physical condition seemed to have a great effect on them (p<0.001).2. In terms of factors related to their roles, job satisfaction and physical condition played in general a greater role for radiological technologists (p<0.001). Immediate seniors and behavioral conducts were also found to have a lot influence on them (p<0.01).3. As for job conflicts, the kind of medical institutions seemed to exercise a great deal of impact on radiological technologists (p<0.05), while colleagues, immediate seniors, job satisfaction and physical conditions also produced a lot of influence on them as a whole (p<0.001).4. Regarding job autonomy, radiological technologists were found to have been less influenced by position in metropolitan cities and by immediate seniors in the capital city (p<0.01). As a whole, however, age and job satisfaction acted as decisive factors of influence on them (p<0.001). 5. Among factors related to job burden, gender played a bigger role for radiological technologists in metropolitan cities as the kind of medical institutions did in small- and medium-sized cities. Centrally, job satisfaction and behavioral conducts exercised a great impact on them (p<0.001).6. Job stability seemed to be more immensely linked to gender and physical conditions in metropolitan cities whereas position did more in the capital city. In general, how ever, job satisfaction produced a far-reaching (p<0.001).

• Microbiology and Biotechnology Letters
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• v.30 no.1
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• pp.15-20
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• 2002

Diacylglycerol kinase (DGK) phosphorylates the second messenger diacylglycerol (DAG) to phosphatidic acid and it may play a role in signal transduction in Escherichia coli as well as in eukaryotic cells. In addition, DGK is important for microorganisms to adapt to several physiological stimuli. In Bacillus subtilis, the effect of stress on dgk transcription was examined by northern hybridization. The high level of dgk transcription was induced against high osmolarity, low pH value and low temperature. Transcriptional analysis revealed that the dgk gene and dgk upstream locus (ORF2, ORF3 and ORF4) were transcribed as a polycistronic mRNA to form an approximately 2.5 kb transcript.

• Journal of Microbiology and Biotechnology
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• v.12 no.2
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• pp.318-326
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• 2002

The pathogenic marine bacterium Vibrio vulnificus is the causative agent of food-borne diseases such as life-threatening septicemia. To better understand this organism's strategies to survive osmotic stress, a mutant that was more sensitive to high osmolarity was screened from a library of mutants constructed by a random transposon mutagenesis. By a transposon-tagging method, putAP genes encoding a proline dehydrogenase and a proline permease were identified and cloned from V. vulnificus. The amino acid sequences deduced from nucleotide sequences of putAP from V. vulnificus were 38 to $59\%$ similar to those of PutA and PutP reported from other Enterobacteriaceae. Functions of putAP genes were assessed by the construction of mutants, whose putAP genes were inactivated by allelic exchanges. When proline as the sole carbon or nitrogen source was used, the putA mutant was not able to grow to the substantial level, revealing the proline dehydrogenase is the only enzyme for metabolic conversion of proline into other amino acids. Although the growth rate of the putP mutant on proline as the sole carbon or nitrogen source was significantly reduced, the mutant still grew. This indicated that at least one more proline permease is produced by V. vulnificus. The putP mutant decreased approximately $2-log_10$ CFU/ml after a hyperosmotic challenge, while the parent strain decreased approximately $l-log_10$ CFU/ml. This result suggests that the gene product of putP contributes to the osmotic tolerance of V. vulnificus.

• Journal of Preventive Medicine and Public Health
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• v.35 no.4
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• pp.282-286
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• 2002

Objectives : The level of 4-hydroxyproline (4-Hyp) in human urine was measured using high performance liquid chromatography (HPLC) with a fluorescence detector. This method is useful for medical examinations and investigating the radicals induced by physical, chemical, mental stresses. This method is superior to many published several methods in terms of its low cost and ability to analyze many samples. Methods : The urine from workers in a tire manufacturing company (22 male pre- and post-shift workers) and 18 office-workers as controls were analyzed. Data concerning age, the cumulative drinking amount and the cumulative smoking amount was collected with a questionnaire. The optimum applied amount of dansyl-Cl, the optimum reaction temperature and time, the recoveries and the optimum pH of the eluent and buffer were determined.4-Hyp from human urine was derivatized with dansyl-Cl (dimethylamino-naphthalene-1-sulfonyl chloride) after removing the a-amino acid by a treatment with phthalic dicarboxaldehyde (OPA) and cleaned with Bond Elut C18 column. The 4-Hyp derivatives were separated on a reversed phase column by gradient elution with a phosphate buffer (5 mmol, pH 8.0) and acetonitrile, and detected by fluorescence measurements at 340 nm (excitation) and 538 nm (emission). Results : The detection limit for the urinary free 4-Hyp was $0.364{\mu}mol/l$. The recovery rate of 4-Hyp was 99.7%, and the effective pH of the phosphate buffer and borate buffer were 3.0 and 8.0, respectively. From statistical analysis, age, drinking and smoking did not affect the urinary free 4-Hyp in both the controls and workers. The range of urinary 4-Hyp in the controls, pre-shift, and post-shift workers were 0.33-16.44, N.D-49.06, and $0.32-56.27{\mu}mol/l$. From the pared-sample t-test, the urinary 4-Hyp levels in post-shift workers ($11.82{\pm}6.73\;nmmol/mg\;Cre$) were 2-fold higher than in pre-shift workers ($5.36{\pm}5.53\;nmol;/mg\;Cre$) and controls ($4.91{\pm}4.89\;nmol;/mg\;Cre$). Conclusions : This method was developed with high sensitivity, accuracy, and precision. The present method was effectively applied to analyze the urinary free 4-Hyp in both controls and workers.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.1
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• pp.124-130
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• 2007

The purposes of this study were (1) to analyze price sensitivity, (2) to define the range of acceptable prices for each foreign segment, and (3) to provide a price model for Korean traditional restaurants. From October to November, 2006, a total of 781 foreigners responded to individual surveys. Statistical analyses on the survey data were performed using descriptive statistics and Price Sensitivity Measurement (PSM). Major findings from the study are as follows: First, the ranges of the acceptable prices were $98$\sim$$130 for fine dining/gourmet restaurants, $70$\sim$$90 for theme/ambience restaurants, $40$\sim$$60 for popular/family restaurants, and $18$\sim$$30 for convenience/fast food restaurants. Second, the convenience/fast food restaurants showed the highest price sensitivity. Third, a low stress level and wide range of the acceptable price were observed for the fine dining/gourmet restaurants, suggesting that the price sensitivity of the fine dining/gourmet restaurants was quite low. Finally, the price sensitivity indicated by the Japanese was higher than by the other groups. In consequence, the research findings suggest that the managers of the Korean traditional restaurants should strategically plan prices by understanding different customers' price sensitivity within and between customer segments. Through additional research, marketers can compare perceptions of specific brands, the competition, and variations within a product line.