• Nutrition Research and Practice
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• v.9 no.1
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• pp.37-42
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• 2015

BACKGROUND/OBJECTIVES: Red grape seeds as functional food are a good source of important bioactive components such as phenolics and antioxidants, which decrease oxidative stress that contributes to the pathogenesis of hepatotoxicity. The current study was conducted in order to evaluate the protective effect of red grape dried seeds (RGDS) on antioxidant properties, lipid metabolism, and liver and kidney functions of rats with paracetamol (750 mg/kg) induced hepatotoxicity. MATERIALS/METHODS: RGDS was added to the basal diet at 5, 10, and 20%. Thirty five adult male rats were assigned to five groups (n = 7) for a six-week feeding period; group (1) normal control, group (2) induced control, groups (3, 4, and 5) fed a diet with RGPS at different levels, 5, 10, and 20%, respectively. At the end of the feeding period, animals' blood and tissues were collected for estimation of serum lipid profile, serum liver, and kidney biomarkers. The protection was measured by detecting lipid peroxidation (LPO), glutathione (GSH), superoxide dismutase (SOD), Catalase (CAT) (in liver tissues), and liver histological examination. RESULTS: The results showed a significant (P < 0.05) decrease in levels of serum cholesterol, triglycerides, low density lipoprotein (LDL-C), and very low density lipoprotein (VLDL-C), with a significant increase in level of high density lipoprotein (HDL-C) for RGDS groups compared to induced control. Rats administered a diet containing RGDS levels produced significant (P < 0.05) hepatoprotection by decreasing the activities of liver enzymes, kidney parameters, and lipid peroxidation, while levels of GSH, SOD, and CAT were increased significantly to near the normal levels. CONCLUSION: The RGDS 20% group was more effective than others against hepatotoxicity of paracetamol, which may be attributed to RGDS total phenols and antioxidant contents, which were 1.438 mg and 1.231 mg, respectively.

• Journal of the Korean Institute of Gas
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• v.17 no.1
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• pp.19-25
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• 2013

The joining methods of steel structures of gas facilities, bridges, ships etc. by welding are composed mostly of T-type or cruciform fillet welding and full penetration or partial penetration according to the uses and the shape of the structures. In this study, it was examined the characteristics of fatigue crack according to penetration depth in relation to material thickness in the cruciform fillet welded joints. From the results, it was investigated the safe design stresses within the range of infinite life. When the LOP length is long the range of infinite life is small with root failure and when the LOP length is short the range of infinite life is large with teo failure. For the specimen of material thickness, 20mm welded by 3 pass compared with 10mm, 15mm welded by 2 pass, the fatigue strength and the range of infinite life was more improved by increasing of notch toughness from formation of micro-ferrite acicular structure.

• Journal of the Korean Society of Marine Environment & Safety
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• v.10 no.2 s.21
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• pp.41-47
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• 2004

Plate has cutout inner bottom and girder and Door etc. in hull construction absence is used much, and this is strength in case must be situated, but establish in region that high stress interacts sometimes fatally in region that there is no big problem usually by purpose of weight reduction, a person and freight movement, piping etc.. Because cutout‘s existence is positioning in this place, and, elastic bucking strength by load causes large effect in ultimate strength. Therefore, perforated plate elastic bucking strength and ultimate strength is one of important design criteria to decide structural elements size at early structure design step of a ship. Therefore, we need reasonable & reliable design formula for elastic bucking strength of the perforated plate. The author computed numerically ultimate strength change about several aspect ratios, cutout dimension, and plate thickness by using ANSYS Finite element analysis code based on finite element method in this paper.

• International Journal of Automotive Technology
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• v.5 no.3
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• pp.215-219
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• 2004

A vehicle structure needs to be more precisely analyzed because of complexities and varieties. Structural fatigue which is generated by fluctuations of stresses during the service life of a mechanical system is the primary concern in the structural design for safety. A fatigue life is difficult to obtain in structural components during the service life of mechanical systems since the fluctuating stress contributes to fatigue. This study introduces new procedures to measure the lethargy coefficient and to predict the fatigue life of a mechanical structure by using molecular dynamic simulation. A lethargy coefficient is the total defect-estimating coefficient, which was obtained by using the results of a simple tensile test in this study. With this lethargy coefficient, fatigue life was estimated. The proposed method will be useful in predicting the fatigue life of a structurally-modified vehicle design. The effectiveness of the proposed method using lethargy coefficient measurement to predict the fatigue life of a structure was examined by applying this method to predict the fatigue life of SS41 steel, used extensively as material of vehicle structures. Two types of specimen such as pre-cracked plate and simple plate is discussed. equation of fatigue life using the lethargy coefficient and failure time, both obtained from a simple tensile test, will be useful in engineering. This measurement and prediction technology will be extended for use in analysis of any geometric shapes of modified automotive structures.

• Journal of Korean Tunnelling and Underground Space Association
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• v.18 no.2
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• pp.183-193
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• 2016

Estimation of the stability of an operating tunnel through a back analysis is a difficult concept to analyze. Specially, when a relatively thick lining is constructed as in case of a subsea tunnel, there will be a limit to the use of displacement-based tunnel back analysis because the corresponding displacement is too small. In this study, DEA is adopted for tunnel back analysis and the feasibility of DEA for back analysis is evaluated. It is implemented in the finite difference code FLAC3D using its built-in FISH language. In addition, the stability of a tunnel lining will be evaluated from the development of displacement-based algorithm and its expanded algorithm with conformity of several parameters such as stress measurements.

• International Journal of Highway Engineering
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• v.6 no.4 s.22
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• pp.101-108
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• 2004

Asphalt overlay method is a general method to extend the of life old concrete pavements. However, reflection cracks are the typical problem of the AC overlay on distressed concrete pavement. Joint sealing, stress absorbtion layer have been used to prevent reflection cracks however partial success of to delay the timing of reflection cracking was recognized. Reflection crack problem can be eliminated by using rubblization method, which crush concrete pavement slab into piece of aggregate size that can be used base material. Previous research on rubblization method indicated that the size of rubblized PCC ranged 40-70mm at upper layer, and more than 100mm at lower layer. In this study, the adequate depth of rubblized PCC that ran prevent reflection cracking of AC overlay is estimated base on the simulation test of reflection cracking with 0, 10, 20cm rubblized PCC base.

• Tunnel and Underground Space
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• v.21 no.2
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• pp.109-116
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• 2011

In this study, we estimated the dynamic tensile strength and strain rate from Brazilian tensile test using Split Hopkinson Pressure Bar (SHPB) system. A pulse shaping technique, which controls the shape of the impactinduce incident waves, was used for achieving the dynamic stress equilibrium and constant strain rate before fracture of rock samples. Three kinds of rock type, Inada granite, Kimachi sandstone and Tage tuff were prepared as 50mm in diameter and 26 mm in thickness. The high-speed videography system was used to observe the fracture processes of the rock samples. As the results of the tests, the ratio of dynamic tensile strength and static tensile strength was 11.9 for Inada granite, 8.5 for Kimachi sandstone and 9.2 for Tage tuff.

• Journal of the Society of Naval Architects of Korea
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• v.41 no.6
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• pp.75-83
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• 2004

Ice rubble pieces broken by the bow impact load and side hull of an icebreaking vessel usually pass along the ship's bottom hull and may hit the propeller/rudder or other stern structures causing serious damage to ship's hull . Therefore it is important to estimate the size of broken ice pieces during the icebreaking process. The dynamic interaction process of icebreaker with infinite ice sheet is simplified as a wedge type beam of finite length supported by elastic foundation. The wedge type ice beam is leaded with vertical impact forces due to the inclined bow stem of icebreaking vessels. The numerical model provides locations of maximum dynamic bending moment where extreme tensile stress arises and also possible fracture occurs. The model can predict a failure length of broken ice sheet given design parameters. The results are compared to Nevel(1961)'s analytical solution for static load and observed pattern of ice sheet failure onboard an icebreaker. Also by comparing computed failure length with the characteristic length, the meaning of ice rubble sizes is discussed.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.581-584
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• 2008

In this study, it is willing to present that fundamental data for proposing quantitatively shrinkage cracking evaluation method such as plat-ring type restrained test method. To examine suitable size of specimen of plat-ring type restrained test method, Evaluated concrete about restrained shrinkage crack properties of numerical analysis of 3D solid element using the MIDAS program, drying shrinkage deformation, restrained shrinkage stress, crack area and crack point with inside ring diameter of specimen in 100mm, 150mm, 200mm and high of Specimen in 30mm, 50mm after curing in condition of constant temperature and usual habit of temperature 20${\pm}$3$^{\circ}$C, humidity 60${\pm}$5%. As a result, it was available about suitable estimation with inside ring diameter of specimen in more than 150mm and high of Specimen in 50mm. Hereafter, it is considered that the study concerning environmental condition and mixing factor in plat-ring type restrained test method is need.

• Journal of the Korean Geotechnical Society
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• v.19 no.5
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• pp.175-187
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• 2003

The earth pressure acting on the cylindrical retaining wall in cohesionless soils is different from that on the retaining wall in plane strain condition due to three dimensional arching effect. Accurate estimation of earth pressure is required for the design of vertical cylindrical retaining wall. Failure modes of the ground behind vertical shaft are dependent on ground in-situ stress conditions. Failure modes are actually divided into two modes of cylindrical failure mode and funnel-shaped mode with truncated cone surface. Several researchers have attempted to estimate the earth pressure on cylindrical wall for each failure mode, but they have some limitations. In this paper, several equations for estimating the earth pressure on cylindrical wall in cohesionless soils are investigated and new formulations for two failure modes are suggested. It rationally takes into account the overburden pressure, wall friction, and force equilibriums on sliding surface.