• Journal of Integrative Natural Science
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• v.9 no.2
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• pp.86-93
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• 2016

The peptide sequences, GHK(Gly-His-Lys) and KTTKS(Lys-Thr-Thr-Lys-Ser), using a collagen stimulator recently were manipulated at N-terminal as a multifunctional peptide derivative with PEG(polyethyleneglycol) linker connected to gallic acid which presents anti-inflammatory activity. The multifunctional peptide derivatives were obtained in a normal peptide preparation method through SPPS(solid phase peptide synthesis) using Fmoc chemistry and a carboxyl group insertion reaction of PEG-3,4,5-triacetoxy benzoate by using potassium tert-butoxide and ethyl bromoacetate, which was separated by Sephadex DEAE. It gave a good compromise to a cosmetic application for cell cytotoxicity, anti-wrinkle, and anti-inflammation.

• International journal of advanced smart convergence
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• v.6 no.4
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• pp.19-25
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• 2017

After 40 years of age, the saliva glands are aged and the saliva is not made enough to cause xerostomia symptoms. Side effects such as hypertension medication or diuretics that the elderly take mainly can cause xerostomia syndrome. In addition, autoimmune diseases, diabetes, anemia, depression and other common diseases that cause xerostomia symptoms. If the saliva secretion is insufficient, tooth decay and gum disease are likely to occur, and the digestive ability of the saliva is also reduced due to the lack of amylase, which is a digestive element. Once the degenerated salivary gland is restored to its normal state, it is difficult to recover. In this paper, we give electrical stimulation to the masseter which is in contact with the large pituitary gland, and stimulate the salivary gland to the utmost by using speech recognition using words corresponding to oral gymnastics. Use the STM32F407VG to implement a system to relieve xerostomia.

• Journal of the Korean Institute of Landscape Architecture
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• v.26 no.1
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• pp.36-43
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• 1998

We compared the electroencephalogram, blood pressure, and sensory evaluation inspectioni several color of Petunia hybrida to analyze the physiopsychological effects of a plant. Considering occipital is related to visuosensory field, green color is thought as mild visual stimulator unlike to pink color. The results are coincident with the well-known facts that green color is less stimulating color. It is also accorded with the sensory evaluation results that green color showed te feeling of blue and stable. In case of green color is showed the feeling of blue and stable. In case of green color the generatioin of alpha waves increased according to the increase color area. Therefore it is thought that green color helps decrease of visual stimulation and increase in visual stability. However it is thought that pink has less physiopsychological effects on human beings depending on area sizes than green has.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.289-293
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• 2003

Schizophyllum commune belongs to Basidiomycetes is able to produce an extracellular polysaccharide, beta-glucan, which has been well known as an effective immune stimulator. In other to obtain the optimum conditions for the polysaccharide production, Schizophyllum commune was cultivated in different cultivation media containing various carbon and nitrogen sources. For the cell growth and the polysaccharide production, the optimum synthetic medium was developed with YMP medium an a basal midium. The flask culture conditions for the polysaccharide production were $27^{\circ}C$ and 150rpm with the initial pH 5.5.

• The Korean Journal of Ecology
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• v.15 no.2
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• pp.127-135
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• 1992

The effects of nacl concentration, temperatura, light and growth regulator(GA3, kinetin) on the tuber germination of s. maritimus were investigated. The germination percentage increased with decreasing nacl, showing salt tolerance through time, and with increasing temperature untile 20~30oC light / dark (12/12 hr) of optimal temperature. The multiplication of nacl and temperature on germination percentage and velocity, increased significantly in higher temperature than lower temperature in saline. The germination percentage showed high value in dark condition than in light condition which is the charracteristics of underground organ. and ga3 act as germination stimulator to overcome the inhibitory effect of nacl. The effect of ga3 showed significant differances on tubers of s. maritimus of germination but that of kinetin had a litter sffects on germination. Factors of nacl and temperature interacted significantly and the effects of nacl on germination percentage and velocity depended on temperature condition.

• Journal of information and communication convergence engineering
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• v.6 no.4
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• pp.411-416
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• 2008

When compose magnetic field curer by belt and band style and need by magnetic field ripple last month, produce self-discipline roof. Bred in muscle disease (lumbago, backbone disease, corpulence) back. Result that study, manufactured various variableness band style - magnetic field probe firstly. Can establish self-discipline treatment pulse price by disease secondly. Could seek correct variableness band punishment, - magnetic field probe relationship implementation and property in waist, and so on, shoulder, neck, arm, leg, ankle, wrist etc. by third. Could find variableness band style energy value that need in-magnetic field Probe's treatment by fourth. This research could design pulse of self-discipline in band form and apply each according to disease.

• BMB Reports
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• v.30 no.6
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• pp.385-389
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• 1997

Many cell types are known to stimulate $CD8^+$ T cells in allogeneic recognition such as mixed lymphocyte reaction (MLR). Whereas dendritic cells are most potent among them. T cells are usually considered very poor in stimulating $CD8^+$ T cells although there are some tumor cells that are weakly stimulatory. T cells, as a stimulator, cultured in the presence of concanavalin A that were otherwise nonstimulatory to $CD8^+$ T cells appeared to stimulate $CD8^+$ T cells strongly when they were pretreated with neuraminidase. The enhancement of MLR by neuraminidase could be achieved by treating either the stimulators or responders with neuraminidase. Removal of negatively-charged sialic acid moieties from the cell surface, which reduced electrostatic repulsion between responders and stimulators to give better cell-cell contact might be responsible for the enhanced MLR. In addition, neuraminidase treatment also appeared to deliver activation signal to responding T cells since it could activate $CD8^+$ T cells in synergy with phorbol myristate acetate. The maximal responses were observed when both responders and stimulators were treated with neuraminidase.

• Journal of Biomedical Engineering Research
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• v.12 no.1
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• pp.1-7
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• 1991

This paper describes and discusses the employment of HMG pattern analysis to provide upper-motor-neuron paraplegics with patient-responsive control of FES ( functional electrical stimulation) for the purpose of walker-supported walking. The use of above-lesion EMG signals as a solution to the control problem is considered. The AR(autoregressive)parameters are identified by time-varying nonstationary Kalman filler algorithm using DSP chip and classified by fuzzy theory. The control and stimuli part of the below-lesion are based on micro-processor(8031). The designed stimulator is a 4-channel version. The experiments described above have only attempted to discriminate between standing function and sit-down function A further advantge of the this system Is applied for motor rehabilitation of social readaption of paralyzed humans.

• Proceedings of the KAIS Fall Conference
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• 2012.05b
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• pp.808-811
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• 2012

매년 높은 비율의 전기안전사고가 발생하지만 예방교육은 단순한 영상홍보나 단순 텍스트를 이용한 교육 수준에서 주입식으로 이루어지고 있다. 항공, 군사, 전력산업 등 다양한 분야에서는 가상현실을 이용한 체험형 교육 시스템이 개발되어 운영되지만 전기안전 예방교육은 감전사고와 같은 특수한 상황의 체험과 사고를 유발시킬 수 있다는 측면에서 체험형 교육시스템이 개발 및 적용이 어렵다. 따라서 본 연구에서는 전기감전 체험교육 시스템에 저주파 자극 장치를 사용할 수 있도록 저주파 간섭형 자극기를 이용한 인체 자극의 임계값 산출시험을 실시하고 대표적으로 성별, 연령별(아동 및 성인 구분)로 구분하여 적절한 자극값을 산출하였다. 본 연구의 결과는 향후 전기안전사고 예방을 위한 체험형 예방 교육 시스템에 활용이 가능할 것이다.

• The Korean Journal of Pain
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• v.23 no.1
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• pp.78-81
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• 2010

Spinal cord stimulation (SCS) has become an established clinical option for treatment of refractory chronic pain. Current hardware and implantation techniques for SCS are already highly developed and continuously improving; however, equipment failures over the course of long-term treatment are still encountered in a relatively high proportion of the cases treated with it. Percutaneous SCS leads seem to be particularly prone to dislocation and insulation failures. We describe our experience of lead breakage in the inserted spinal cord stimulator to a complex regional pain syndrome patient who obtained satisfactory pain relief after the revision of SCS.