• Title/Summary/Keyword: stepwise multiple linear regression analysis

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Is it Possible to Predict the ADI of Pesticides using the QSAR Approach?

  • Kim, Jae Hyoun
    • 한국환경보건학회지
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    • 제38권6호
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    • pp.550-560
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    • 2012
  • Objectives: QSAR methodology was applied to explain two different sets of acceptable daily intake (ADI) data of 74 pesticides proposed by both the USEPA and WHO in terms of setting guidelines for food and drinking water. Methods: A subset of calculated descriptors was selected from Dragon$^{(R)}$ software. QSARs were then developed utilizing a statistical technique, genetic algorithm-multiple linear regression (GA-MLR). The differences in each specific model in the prediction of the ADI of the pesticides were discussed. Results: The stepwise multiple linear regression analysis resulted in a statistically significant QSAR model with five descriptors. Resultant QSAR models were robust, showing good utility across multiple classes of pesticide compounds. The applicability domain was also defined. The proposed models were robust and satisfactory. Conclusions: The QSAR model could be a feasible and effective tool for predicting ADI and for the comparison of logADIEPA to logADIWHO. The statistical results agree with the fact that USEPA focuses on more subtle endpoints than does WHO.

방화 발생에 영향을 미치는 요인에 관한 연구 (A Study on the Factors Affecting the Arson)

  • 김영철;박우성;이수경
    • 한국화재소방학회논문지
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    • 제28권2호
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    • pp.69-75
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    • 2014
  • 본 연구에서는 방화발생에 영향을 미치는 요인을 도출하기 위하여 발생건수를 종속변수로 하고 경제 인구 사회적 요인을 독립변수로 하는 다중회귀분석을 실시하였다. 다중회귀분석은 선형함수, 준로그함수, 역준로그함수, 이중로그함수 4가지 함수형태에 대해 적용하였으며, 각 단계별로 변수의 선택과 제외를 고려하는 단계적선택 방식을 적용하였다. 다중공선성 문제와 자기상관 문제를 해결하기 위하여 분산확대지수(VIF)와 Durbin-Watson 계수 이용하였으며, 4가지 함수모형에 대하여 수정된 R 제곱(설명력) 값이 0.935 (93.5%)로 가장 값이 높고 통계적으로 유의한 선형함수모형을 최적의 모형으로 결정하고 모형에 대한 해석을 진행하였다. 선형함수모형 결과 방화발생에 영향을 미치는 요인은 범죄발생건수(0.829), 일반이혼율(0.151), 재정자주도(0.149), 소비자물가상승률(0.099) 순으로 도출되었다.

한국형 파킨슨 환자의 역학적 기능수행지수 개발 (Developing an Biomechanical Functional Performance Index for Parkinson's Disease Patients)

  • Shin, Sunghoon;Han, Byungin;Chung, Chulmin;Lee, Yungon
    • 한국운동역학회지
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    • 제30권1호
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    • pp.83-91
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    • 2020
  • Objective: The study aimed to develop a functional performance index that evaluates the functional performance of Parkinson's patients, i.e., to integrate biomechanical measurements of walking, balance, muscle strength and tremor, and to use multiple linear regression with stepwise methods to identify the most suitable predictors for the progression of disease. Method: A total of 60 subjects were tested for sub-variables of four factors: walking, balance, isometric strength and hand tremors. Potential independet variables were extracted through correlation analysis of the sub-variables and dependent variables, Hoehn & Yahr scale. And then, a stepwise multiple regression analysis using the potential independent variables was performed to identify predictor of Hoehn & Yahr scale. Results: First, the results of the study showed that physical composition and gait had a relatively more correlated with the progression of the disease, compared to balance and hand tremor. Second, Parkinson's functional performance is characterized by dynamic pattern of walking, such as foot clearance and turning angle (TA) of walking, and a high-explained regression model is completed. Conclusion: The study emphasized the importance of walking variables and body composition in minor pathological features compared to Parkinson's patient's balancing ability and hand tremor. Specifically, it revealed that dynamic walking patterns functionally characterize patients. The results are worth considering when assessing functional performance related to the progression of the disease at the site.

다중 회귀 분석을 이용한 한자 난이도 예측 기법 연구 (Prediction Techniques for Difficulty Level of Hanja Using Multiple Linear Regression)

  • 최정환;노지우;김순태
    • 한국인터넷방송통신학회논문지
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    • 제19권6호
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    • pp.219-225
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    • 2019
  • 한자 급수와 같이 기존 한자 난이도 선정 방식에 문제점이 있다. 실생활에서 쓰이는 한글 단어와 차이가 나며 해당 급수가 실제로 얼마나 많이 쓰이는지 알 수가 없다. 이러한 문제를 해결하기 위해 빈도수를 이용하여 다중 회귀 분석을 이용하여 한자 난이도를 측정한다. 초등 교과서를 기반으로 한자활용빈도수와 한글의미빈도수를 집계한다. 두 빈도수와 획수를 함께 사용하여 설문지를 작성하여 해당 한자의 학습 적정 시기를 답변 받아 이를 회귀에서 사용할 타겟 변수로 이용한다. 단계별 회귀분석을 이용하여 적절한 피처를 선택하고 다중 선형 회귀 분석을 한다. 모델의 R2는 0.1105가 나왔으며 RMSE는 0.1105의 결과가 나왔다.

QSPR Study of the Absorption Maxima of Azobenzene Dyes

  • Xu, Jie;Wang, Lei;Liu, Li;Bai, Zikui;Wang, Luoxin
    • Bulletin of the Korean Chemical Society
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    • 제32권11호
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    • pp.3865-3872
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    • 2011
  • A quantitative structure-property relationship (QSPR) study was performed for the prediction of the absorption maxima of azobenzene dyes. The entire set of 191 azobenzenes was divided into a training set of 150 azobenzenes and a test set of 41 azobenzenes according to Kennard and Stones algorithm. A seven-descriptor model, with squared correlation coefficient ($R^2$) of 0.8755 and standard error of estimation (s) of 14.476, was developed by applying stepwise multiple linear regression (MLR) analysis on the training set. The reliability of the proposed model was further illustrated using various evaluation techniques: leave-many-out crossvalidation procedure, randomization tests, and validation through the test set.

Characterization of Aroma Components in Barley Bran Sauce Using Statistical Analysis

  • Choi, Ung-Kyu;Kim, Mi-Hyang;Kwon, O-Jun;Lee, Tae-Jong;Lee, Nan-Hee
    • Food Science and Biotechnology
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    • 제16권1호
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    • pp.23-28
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    • 2007
  • A linear correlation was found by stepwise multiple regression analysis between the sensory score of barley bran sauce aroma and the absolute gas chromatogram (GC) data transformed with square root. In spite of highly significant relationship between the quantity of the peak and the sensory score, it is difficult to estimate the aroma quality of barley bran sauce samples on the basis of only one peak. Peak 29 (methyl 9,12,15-octadecatrienoate) contributed most to the aroma of barley bran sauce. This was followed by 27 (methyl 9,12-octadecadienoate), 28 (ethyl 9,12-octadecadienoate), 12 (phenyl acetaldehyde), and 9 (methyl furfural) in terms of absolute value. When it was calculated using absolute value transformed by square root, peak 28 (ethyl 9,12-octadecadienoate) made the highest contribution to the aroma of barley bran sauce of among the peaks. It was followed by 31 (9,12-octadecadienoic acid), 27 (methyl 9,12-octadecadienoate), 12 (phenyl acetaldehyde), and 29 (methyl 9,12,15-octadecatrienoate).

기상요소와 MODIS NDVI를 이용한 한국형 논벼 생산량 예측모형 (KRPM)의 개발 (Development of Korean Paddy Rice Yield Prediction Model (KRPM) using Meteorological Element and MODIS NDVI)

  • 나상일;박종화;박진기
    • 한국농공학회논문집
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    • 제54권3호
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    • pp.141-148
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    • 2012
  • Food policy is considered as the most basic and central issue for all countries, while making efforts to keep each country's food sovereignty and enhance food self-sufficiency. In the case of Korea where the staple food is rice, the rice yield prediction is regarded as a very important task to cope with unstable food supply at a national level. In this study, Korean paddy Rice yield Prediction Model (KRPM) developed to predict the paddy rice yield using meteorological element and MODIS NDVI. A multiple linear regression analysis was carried out by using the NDVI extracted from satellite image. Six meteorological elements include average temperature; maximum temperature; minimum temperature; rainfall; accumulated rainfall and duration of sunshine. Concerning the evaluation for the applicability of the KRPM, the accuracy assessment was carried out through correlation analysis between predicted and provided data by the National Statistical Office of paddy rice yield in 2011. The 2011 predicted yield of paddy rice by KRPM was 505 kg/10a at whole country level and 487 kg/10a by agroclimatic zones using stepwise regression while the predicted value by KOrea Statistical Information Service was 532 kg/10a. The characteristics of changes in paddy rice yield according to NDVI and other meteorological elements were well reflected by the KRPM.

수박 내부결함판정을 위한 휴대형 압전형 장갑 센서시스템 (Portable Piezoelectric Film-based Glove Sensor System for Detecting Internal Defects of Watermelon)

  • 최동수;이영희;최승렬;김학진;박종민
    • Journal of Biosystems Engineering
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    • 제33권1호
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    • pp.30-37
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    • 2008
  • Dynamic excitation and response analysis is an acceptable method to determine some of physical properties of agricultural product for quality evaluation. There is a difference in the internal viscoelasticity between sound and defective fruits due to the difference of geometric structures, thereby showing different vibration characteristics. This study was carried out to develop a portable piezoelectric film-based glove sensor system that can separate internally damaged watermelons from sound ones using an acoustic impulse response technique. Two piezoelectric sensors based on polyvinylidene fluoride (PVDF) films to measure an impact force and vibration response were separately mounted on each glove. Various signal parameters including number of peaks, energy ratio, standard deviation of peak to peak distance, zero-crossing rate, and integral value of peaks were examined to develop a regression-estimated model. When using SMLR (Stepwise Multiple Linear Regression) analysis in SAS, three parameters, i.e., zeros value, number of peaks, and standard deviation of peaks were selected as usable factors with a coefficient of determination ($r^2$) of 0.92 and a standard error of calibration (SEC) of 0.15. In the validation tests using twenty watermelon samples (sound 9, defective 11), the developed model provided good capability showing a classification accuracy of 95%.

우리나라 일부 중년층 남녀의 암에 대한 예방적 건강행위 이행에 관한 연구 (A STUDY ON MIDDLE AGED PEOPLE'S COMPLIANCE FOR PREVENTIVE HEALTH BEHAVIOR OF CANCER)

  • 김은주;문인옥
    • 보건교육건강증진학회지
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    • 제4권2호
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    • pp.9-31
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    • 1987
  • This study was conducted because of the investigator's concern for the high incidence and fatal nature of cancer in prime years of human life. The purpose of this study was to investigate risk factors on compilance for preventive health behavior of cancer. The data on which the analysis was based come from a survey of 828 married men & women, 40-59 years old. The instrument of the study were 'Health Belief Model' by Becker. The Data was analyzed using X--test, t-test, ANOVA, Pearson's Correlation Coefficient, Stepwise Multiple Regression. The followings were the result; 1. The examined group had a higher scores than the non-examined group in health belief variables. (p<0.001) 2. The higher level of health belief variables, the higher level of compliance for preventive health behavior is. (p<0.001) 3. The Stepwise Multiple Regression of compliance for preventive health behavior on the variables in the health belief model; Approximataly 65.5% of the variance of compliance for preventive health behavior was accounted for by health concern, susceptibility and barriers in combination. This meant that other factors seemed to influence preventive health behavior since the linear combination of variables failed to explain the remaining 34.5% of preventive health behavior of cancer. It tended to cost doubt on the usefulness of 5 variables in this model. Therefore further study to investigate the influential factors preventive health behavior of cancer is necessary.

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항암 화학요법을 받는 유방암 환자의 피로 관련요인 (Factors Related to Fatigue in Breast Cancer Patients Receiving Chemotherapy)

  • 권영은
    • 성인간호학회지
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    • 제17권2호
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    • pp.310-319
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    • 2005
  • Purpose: The purpose of the study is to investigate the degree of fatigue and its related factors in patients with breast cancer. Method: The subjects of this study consisted of 62 breast cancer patients receiving chemotherapy. The Revised Piper Fatigue Scale, Disruption of Usual Activity Scale, Linear Analogue Self Assessment Scale and Self-Care Diary Scale were employed to measure fatigue, disruption of usual activity, mood state and physical symptom respectively. Collected data were analyzed using SPSS-PC to obtain summary statistics for the descriptive analysis, Pearson Correlation, and Stepwise Multiple Regression. Result: The results are as follows. 1. The mean score of the degree of fatigue was 4.82 points indicating moderate level. 2. The mean score of the degree of disruption of usual activity, mood state and physical symptom were 2.66, 5.00, and 4.69 points. 3. Fatigue of the subjects was significantly correlated with disruption of usual activity(r=.517, p<.01), mood state(r=.420, p<.01) and physical symptom(r=.463, p<.01). 4. With the result of stepwise multiple regression, disruption of usual activity, mood state and physical symptom being the three variables which could explain fatigue by 39.1%. The results of this study suggest that comprehensive intervention strategy for fatigue should be developed to maintain quality of life during and following chemotherapy considering these factors.

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