• Hip & pelvis
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• 제34권4호
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• pp.211-218
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• 2022

Purpose: We report on the 10-year clinical hip function and radiologic outcomes of patients who underwent hip arthroplasty using a COREN stem. Materials and Methods: A consecutive series of 224 primary cementless hip arthroplasty implantations were performed using a COREN stem between 2009 and 2011; among these, evaluation of 128 hips was performed during a minimum follow-up period of 10 years. The mean age of patients was 65.4 years (range, 40-82 years) and the mean duration of follow-up was 10.8 years (range, 10-12 years). Evaluation of clinical hip function and radiologic implant outcomes was performed according to clinical score, thigh pain, and radiologic analysis. Results: Dramatic improvement of the mean Harris hip score (HHS) from 59.4 preoperatively to 93.5 was observed at the final follow-up (P≤0.01). Stable fixation was demonstrated for all implants with no change in position except for one case of Vancouver type B2 periprosthetic femur fracture. A radiolucent line (RLL) was observed in 16 hips (12.5%). Thigh pain was observed in only two hips (1.6%) at the final follow-up. There were no cases of osteolysis around the stem. The survival rate for the COREN stem was 97.7%. Conclusion: Good long-term survival with excellent clinical and radiological outcomes can be achieved using the COREN femoral stem regardless of Dorr type.

• 한국산림과학회지
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• 제90권3호
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• pp.331-337
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• 2001

본 연구에서는 PC기반의 Windows운영체제에서 운용될 수 있는 수간석해 프로그램(Stemwin1.0)을 개발하였다. Stemwin1.0에서는 연륜측정기에서 1/100mm 단위로 측정된 l년 단위의 연륜폭 자료를 입력받아 흉고직경 및 단면적, 수고, 재적 등 각종 생장량을 다양한 방법으로 계산할 수 있다. 즉, 수령별 평균 흉고직경 및 단면적은 산술 및 단면적 평균법을 적용해 계산할 수 있으며, 수고생장은 평행선법, 직선연장법, 수고곡선법 등에 의해 다양하게 추정할 수 있다. 재적은 Huber식, Smalian식, Spline식 등을 선택적으로 적용해 추정할 수 있다. 선택된 계산방법에 따라 상가 각 생장인자의 총, 평균 및 연년 생장량 뿐만 아니라 이용재적 및 수고, 형수, 생장률 이용률 등의 생장 관련 정보가 1년 단위로 자동 계산된다. 또한, 1년 단위의 정밀한 간곡선도를 다양한 축척으로 출력할 수 있으며 간곡선식 유도를 위한 통계분석용 자료(단판 높이별 직경)도 제시된다. Stemwin1.0에서는 계산결과를 MS-Excel로 전환할 수 있도록 하여 사용자가 손쉽게 활용할 수 있도록 하였다.

• 한국환경과학회지
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• 제31권11호
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• pp.941-950
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• 2022

This study was conducted to provide data and stem information to establish a local volume table of Cryptomeria japonica in Jeju Island. Stem analysis was performed on 26 trees by selecting two average trees from each site of the 13 plots of C. japonica stands in 2021 and 2022. During the analysis stage, one outlier tree was rejected, and a total of 260 observations of the specific stem height of 25 trees were used. Of the seven major taper equation models applied for parameter estimation and statistical verification, the Muhairwe 1999 model was found to be the best fit and selected as the optimal model. Stem shape-related estimates were acquired through the selected model, and sectional measurements according to the Smalian formula applied at an interval of 10 cm from the height of the stem were used to develop a volume table. A paired t-test comparison between the C. japonica volume obtained from the present study and those selected from the current yield table by NIFoS(2020), revealed significant differences (p<0.05), highlighting the necessity of a local volume table for C. japonica in Jeju Island.

• 한국환경과학회지
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• 제33권7호
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• pp.453-462
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• 2024

This study was carried out for the purpose of selecting the most appropriate taper equation for the actual stands of Pinus thunbergii in the southern coastal region of Korea and then developing a stem volume table to provide basic data for rational management. To develop a volume table of Pinus thunbergii in this region of Korea, 59 sample trees with various diameter distributions were selected and stem analysis was performed. As a result of stem analysis, two trees with abnormal diameter and height growth as the age increased were rejected, and 57 trees were analyzed. To develop the taper equation, seven major variable exponential equations were used, including Kozak 1988, 1994, 2001, 2002, Bi 2000, Muhairwe 1999, and Sharma and Parton 2009. As a result of parameter estimation and statistical verification, the Kozak 1988 model showed the highest goodness of fit with Fit I (Fit Index), RMSE 1.5620, Bias 0.0031, and MAD 1.0784. The diameter of each 10cm stem ridge for the selected model was estimated, and a stem volume table was produced using the mensuration of division (end area formula) using the Smalian equation. As a result of two-sample T-test for volume table of this study and current yield table, the volume for this study was found to be significantly larger at all observation points (p < 0.001). Even for the same tree species, it is judged that differentiated volume tables are needed for each growth environment characteristic.

• Asian-Australasian Journal of Animal Sciences
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• 제24권1호
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• pp.37-44
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• 2011

Parthenogenetic embryonic stem (pES) cells could provide a valuable model for research into genomic imprinting and X-linked diseases. In this study, pES cell lines were established from oocytes of hybrid offspring of Kunming and 129/Sv mice, and pluripotency of pES cells was evaluated. The pES cells maintained in the undifferentiated state for more than 50 passages had normal karyotypes with XX sex chromosomes and exhibited high activities of alkaline phosphatase (AKP) and telomerase. Meanwhile, these cells expressed ES cell molecular markers SSEA-1, Oct-4, Nanog, and GDF3 but not SSEA-3 detected by immunohistochemistry and RT-PCR. The pES cells could be differentiated into various types of cells from three germ layers in vitro by analysis of embryoid bodies (EBs) with immunohistochemistry and RT-PCR, and in vivo by observation of pES cell-derived teratoma sections. Therefore, the established pES cell lines contained all features of mouse ES cells. This work provides a new strategy for isolating pES cells from Kunming mice, and the pES cell lines could be applied as the cell model in research into genomic imprinting and epigenetic regulation of Kunming mice.

• 대한영양사협회학술지
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• 제15권2호
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• pp.168-178
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• 2009

Hematopoietic stem cell tranntation is being widely used in an attempt to treat many hematological diseases such as leukemia, anemia, and lymphoma. To evaluate the success of hematopoietic stem cell transplantation, it is very important to determine how rapidly engraftment occurs. Therefore, this retrospective study was conducted to determine which factors affected the term of engraftment during hematopoietic stem cell transplantation, while focusing on the oral intake status. To accomplish this, 416 patients who underwent transplant operations at St. Mary's hospital from May 2006 to April 2008 were evaluated. The long-term engraftment group was characterized as having longer fasting days and more frequent vomiting, diarrhea, and oral mucositis incidences than the short-term engraftment group. In addition, the inhibitors of oral intake such as vomiting, diarrhea, and oral mucositis developed frequently between the pre-transplantation and 2 weeks after transplantation. A significantly negative correlation was observed between the oral intake volume and the duration of the oral intake inhibitors. A multiple regression analysis revealed that the frequency of vomiting and oral mucositis during hematopoietic stem cell transplantation, the length of hospitalization, and the hematocrit level in the 2 weeks after hematopoietic stem cell transplantation were significant predictors of engraftment. The results of this study could be used to establish a guideline for nutritional assessment, nutritional goals, and nutritional support for patients during hematopoietic stem cell transplantation.

• 농업생명과학연구
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• 제46권6호
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• pp.43-49
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• 2012

본 연구는 수간곡선식을 이용하여 아까시나무의 입목 수간재적표를 개발하고자 수행하였다. 이용한 수간곡선식은 Kozak 모형이었으며, 모형의 모수를 추정하였다. 추정한 모형은 통계적으로 적합성이 인정되었으며, 잔차분석 결과도 양호한 것으로 판정되었다. 따라서 본 모형이 아까시나무 수간재적표를 조제함에 있어 충분히 이용될 수 있을 것으로 사료된다. 그리고 수간재적표는 이용자의 편의를 위하여 수피 포함 및 수피제외 재적표를 조제하고자, 수피두께추정식을 개발하여 이용하였다. 수피두께추정식 역시 통계적으로 유의성이 인정되었다. 따라서, 본 모형이 아까시나무 수간재적표를 조제함에 있어 충분히 이용될 수 있을 것으로 사료된다. 또한, 국내에서 처음으로 개발한 아까시나무의 수간재적표는 임학뿐 만 아니라 타 분야에 널리 사용되기를 기대한다.

• Journal of Korean Neurosurgical Society
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• 제62권2호
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• pp.153-165
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• 2019

Objective : Spinal cord injury (SCI) is a very serious health problem, usually caused by a trauma and accompanied by elevated levels of inflammation indicators. Stem cell-based therapy is promising some valuable strategies for its functional recovery. Nestin-positive progenitor and/or stem cells (SC) isolated from pancreatic islets (PI) show mesenchymal stem cell (MSC) characteristics. For this reason, we aimed to analyze the effects of rat pancreatic islet derived stem cell (rPI-SC) delivery on functional recovery, as well as the levels of inflammation factors following SCI. Methods : rPI-SCs were isolated, cultured and their MSC characteristics were determined through flow cytometry and immunofluorescence analysis. The experimental rat population was divided into three groups : 1) laminectomy & trauma, 2) laminectomy & trauma & phosphate-buffered saline (PBS), and 3) laminectomy+trauma+SCs. Green fluorescent protein (GFP) labelled rPI-SCs were transplanted into the injured rat spinal cord. Their motilities were evaluated with Basso, Beattie and Bresnahan (BBB) Score. After 4-weeks, spinal cord sections were analyzed for GFP labeled SCs and stained for vimentin, $S100{\beta}$, brain derived neurotrophic factor (BDNF), 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase), vascular endothelial growth factor (VEGF) and proinflammatory (interleukin [IL]-6, transforming growth factor $[TGF]-{\beta}$, macrophage inflammatory protein [MIP]-2, myeloperoxidase [MPO]) and anti-inflammatory (IL-1 receptor antagonis) factors. Results : rPI-SCs were revealed to display MSC characteristics and express neural and glial cell markers including BDNF, glial fibrillary acidic protein (GFAP), fibronectin, microtubule associated protein-2a,b (MAP2a,b), ${\beta}3$-tubulin and nestin as well as anti-inflammatory prostaglandin E2 receptor, EP3. The BBB scores showed significant motor recovery in group 3. GFP-labelled cells were localized on the injury site. In addition, decreased proinflammatory factor levels and increased intensity of anti-inflammatory factors were determined. Conclusion : Transplantation of PI-SCs might be an effective strategy to improve functional recovery following spinal cord trauma.

• Journal of the Korean Wood Science and Technology
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• 제51권5호
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• pp.345-357
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• 2023

The present study conducted a stem analysis to trace growth information of Japanese larch (Larix kaempferi) and predict the future changes in growth volume. For this purpose, six L. kaempferi trees over 47 years old were cut at 1-2 m intervals from a height of 0.2 m, and circular plates of 5 cm thickness were collected for stem analysis. The analysis indicated that approximately 1-8 years are required to grow up to chest height. The annual height and diameter growth increased rapidly until the trees are 15 years old and gradually decreased after 20 years. The volume of 30-year-old trees in Oegam-ri forests, which were well-managed after artificial reforestation, was 0.4837 m³, whereas that in unmanaged Singi-ri forests was 0.1956 m³. Although the volume of individual trees differed greatly depending on the forest management status, it was found that the volume increased by 1.67-1.76, 2.49, and 3.49 times at 40, 50, and 60 years age, respectively, compared to the legal harvesting age 30. Therefore, factors such as the carbon dioxide reduction effect, forest management benefits, and the condition of trees at the site should be considered before harvesting trees.

• Clinics in Shoulder and Elbow
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• 제15권2호
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• pp.65-72
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• 2012

목적: 세가지 기원의 줄기 세포 분화능과 면역표현형을 평가하고자 하였다. 대상 및 방법: 견봉하 점액낭과 골수, 탯줄 혈액 세 개의 군에서 세포를 채취하였다. 견봉하 점액낭과 골수는 견관절 수술 환자군에게 임상적 동의 하에 수술중 채취하였다. 각각의 채취된 세포 및 탯줄 혈액에 대하여 계대 배양을 시행하여 신경 분화군, 지방 분화군, 골 분화군을 평가하였으며 세포 표면 항체를 밝히기 위해 유동세포분석법을 이용하였다. 결과: 견봉하 점액낭 유래 세포에서는 신경분화와 지방 분화는 8예 모두 (100%)에서, 골분화는 8례 중 5예 (62.5%)에서 성공할 수 있었으며 골수 유래 세포의 경우 신경 및 지방 분화 유도한 6례 및 5예 모두 (100%) 분화에 성공하였으나 골분화 유도는 5예 중 4예 (80%)에서 얻을 수 있었다. 반면 탯줄 유래 세포 분화 연구의 경우 신경 분화 유도 67례 중 65예 (97%)에서 지방 분화 연구 54예 중 29예 (53.7%)에서 골 분화 연구 57예 중 39예 (68.4%)에서 성공할 수 있었다. 결론: 탯줄 유래 줄기세포의 분화능과 비교하였을 때 견봉하 점액낭 및 골수 유래 줄기세포의 분화능이 우수함을 알 수 있으며 이는 향후 세포 치료에 있어서 안정성 있는 치료 제공자가 될 수 있을 것으로 보이며 향후 생체 실험 연구의 참고 자료로서도 가치가 있을 것으로 보인다.