• Title/Summary/Keyword: steady-state

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Safety and efficacy of target controlled infusion administration of propofol and remifentanil for moderate sedation in non-hospital dental practice

  • Douglas Lobb;Masoud MiriMoghaddam;Don Macalister;David Chrisp;Graham Shaw;Hollis Lai
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.23 no.1
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    • pp.19-28
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    • 2023
  • Background: Fearful and anxious patients who find dental treatment intolerable without sedative and analgesic support may benefit from moderate sedation. Target controlled infusion (TCI) pumps are superior to bolus injection in maintaining low plasma and effect-site concentration variability, resulting in stable, steady-state drug concentrations. We evaluated the safety and efficacy of moderate sedation with remifentanil and propofol using TCI pumps in non-hospital dental settings. Methods: A prospective chart review was conducted on 101 patients sedated with propofol and remifentanil using TCI pumps. The charts were completed at two oral surgeons and one general dentist's office over 6 months. Hypoxia, hypotension, bradycardia, and over-sedation were considered adverse events and were collected using Tracking and Reporting Outcomes of Procedural Sedation (TROOPS). Furthermore, patient recovery time, sedation length, drug dose, and patient satisfaction questionnaires were used to measure sedation effectiveness. Results: Of the 101 reviewed sedation charts, 54 were of men, and 47 were of women. The mean age of the patients was 40.5 ±18.7 years, and their mean BMI was 25.6 ± 4.4. The patients did not experience hypoxia, bradycardia, and hypotension during the 4694 min of sedation. The average minimum Mean Arterial Pressure (MAP) and heartbeats were 75.1 mmHg and 60.4 bpm, respectively. 98% of patients agreed that the sedation technique met their needs in reducing their anxiety, and 99% agreed that they were satisfied with the sedation 24 hours later. The average sedation time was 46.9 ± 55.6 min, and the average recovery time was 12.4 ± 4.4 min. Remifentanil and propofol had mean initial effect-site concentration doses of 0.96 µ/.ml and 1.0 ng/ml respectively. The overall total amount of drug administered was significantly higher in longer sedation procedures compared to shorter ones, while the infusion rate decreased as the procedural stimulus decreased. Conclusion: According to the results of this study, no patients experienced adverse events during sedation, and all patients were kept at a moderate sedation level for a wide range of sedation times and differing procedures. The results showed that TCI pumps are safe and effective for administering propofol and remifentanil for moderate sedation in dentistry.

Geomorphological and Sedimentological Characteristics of Jangdo Wetland in Shinan-gun, Korea (신안 장도습지의 지형과 퇴적물 특성)

  • CHOI, Kwang Hee;CHOI, Tae-Bong
    • Journal of The Geomorphological Association of Korea
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    • v.17 no.2
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    • pp.63-76
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    • 2010
  • The Jangdo wetland is located on a very gentle slope of the mountain area in Daejangdo island, Shinan-gun, Korea, in which the area of the watershed is estimated at 147,000 m2. The wetland has been regarded as a peat bog without any sedimentological evidence. This study was conducted to analyze the geomorphological and sedimentological characteristics of the wetland. The geographic information system (GIS) was used to analyze the drainage system, and field surveys were conducted to measure the range and depth of wetland deposits. The grain size analysis, organic matter determination, elements analysis and radiocarbon dating were performed on samples from the wetland. As a result, the wetland deposits were about 30 cm deep on average, the mean grain sizes ranged from 50 to 500 μm, and the average C/N ratio was 11.5. The portion of organic matter it contained was only 5~26%, which did not satisfy the peat standards. The radiocarbon ages from the wetland deposits range 180±50 14C yr BP to modern, which indicated that natural and anthropogenic interferences including agricultural activities have continuously happened. We conclude that the Jangdo wetland is still in its infancy, not a steady state, so that it could be very sensitive to a small disturbance.

Characteristics of Noise Induced Hearing Loss of Fishermen Visiting a General Hospital (일개 종합병원을 방문한 어선원에서 발생한 소음성 난청의 특징)

  • You Sun Chung;Chang Hoi Kim
    • Journal of agricultural medicine and community health
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    • v.48 no.1
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    • pp.41-49
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    • 2023
  • Objectives: To obtain audiologic basic data to diagnose the noise induced hearing loss of workers in fisheries. Methods: The charts of the referred fishermen with noise induced hearing loss from November 2022 to February 2023 at a general hospital were retrospectively reviewed. Pure tone audiometry, speech audiometry, auditory brainstem response test and auditory steady state response test were conducted. Results: All of them were men over 60 years of age, and the average duration of exposure to noise was 38.9 ± 10.8 years, and the average symptom duration of hearing loss was 13.4 ± 4.3 years. Although the hearing thresholds in the high frequencies were higher than thresholds in the low frequencies, the audiogram showed a down-sloping pattern without rebound at 8 kHz. 10.5% of the cases had thresholds greater than 75 dB in high frequencies, but 57.9% had thresholds greater than 40 dB in low frequencies. Other hearing test results of fishermen were similar to those of general noise-induced hearing loss. Conclusions: Although the fishermen were exposed to noise for a long time, they recognized hearing loss late. The hearing threshold in lower frequencies of the fishermen was higher than expected. Further studies will be needed to analyze the audiologic characteristics of noise-induced hearing loss of the fishermen after confirming noise exposure by conducting a survey on the working environment, such as the noise level and working hours.

Process Control and Dynamic Optimization of Bio-based 2,3-butanediol Distillation Column (바이오 기반 2,3-butanediol 증류 공정의 제어 및 동적 최적화)

  • Giyeol Lee;Nahyeon An;Jongkoo Lim;Insu Han;Hyungtae Cho;Junghwan Kim
    • Korean Chemical Engineering Research
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    • v.61 no.2
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    • pp.217-225
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    • 2023
  • 2,3-Butanediol (2,3-BDO), which is used in various fields such as cosmetics and fertilizers, is a high value-added substance and the demand for it is gradually increasing. 2,3-BDO produced from the fermentation of microorganisms not only contains by-products of fermentation, but also varies greatly in feed composition depending on fermentation conditions, so it is difficult to efficiently operate the separation process to reach the target purity of the product. Therefore, in this study, through dynamic optimization of the bio-based 2,3-BDO distillation process, the optimal control route was explored to control the 2,3-BDO concentration of the bottom product to 99 wt% or more, when feed concentration changes. Steady and dynamic state process simulation, proportional integral (PI) controller design, and dynamic optimization were sequentially performed. As a result, the error between the 2,3-BDO concentration and the set point of the bottom product was reduced by 75.2%.

Horizontal-Axis Screw Turbine as a Micro Hydropower Energy Source: A Design Feasibility Study (마이크로 수력 에너지원의 수평축 스크류 터빈 : 설계 타당성 연구)

  • SHAMSUDDEEN, MOHAMED MURSHID;KIM, SEUNG-JUN;MA, SANG-BUM;KIM, JIN-HYUK
    • Journal of Hydrogen and New Energy
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    • v.33 no.1
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    • pp.95-104
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    • 2022
  • Micro hydropower is a readily available renewable energy source that can be harvested utilizing hydrokinetic turbines from shallow water canals, irrigation and industrial channel flows, and run-off river stream flows. These sources generally have low head (<1 m) and low velocity which makes it difficult to harvest energy using conventional turbines. A horizontal-axis screw turbine was designed and numerically tested to extract power from such low-head water sources. The 3-bladed screw-type turbine is placed horizontally perpendicular to the incoming flow, partially submerged in a narrow water channel at no-head condition. The turbine hydraulic performances were studied using Computational Fluid Dynamics models. Turbine design parameters such as the shroud diameter, the hub-to-shroud ratios, and the submerged depths were obtained through a steady-state parametric study. The resulting turbine configuration was then tested by solving the unsteady multiphase free-surface equations mimicking an actual open channel flow scenario. The turbine performance in the shallow channel were studied for various Tip Speed Ratios (TSR). The highest power coefficient was obtained at a TSR of 0.3. The turbine was then scaled-up to test its performance on a real site condition at a head of 0.3 m. The highest power coefficient obtained was 0.18. Several losses were observed in the 3-bladed turbine design and to minimize losses, the number of blades were increased to five. The power coefficient improved by 236% for a 5-bladed screw turbine. The fluid losses were minimized by increasing the blade surface area submerged in water. The turbine performance was increased by 74.4% after dipping the turbine to a bottom wall clearance of 30 cm from 60 cm. The final output of the novel horizontal-axis screw turbine showed a 2.83 kW power output at a power coefficient of 0.63. The turbine is expected to produce 18,744 kWh/year of electricity. The design feasibility test of the turbine showed promising results to harvest energy from small hydropower sources.

A Review of Quantitative Landslide Susceptibility Analysis Methods Using Physically Based Modelling (물리사면모델을 활용한 정량적 산사태 취약성 분석기법 리뷰)

  • Park, Hyuck-Jin;Lee, Jung-Hyun
    • The Journal of Engineering Geology
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    • v.32 no.1
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    • pp.27-40
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    • 2022
  • Every year landslides cause serious casualties and property damages around the world. As the accurate prediction of landslides is important to reduce the fatalities and economic losses, various approaches have been developed to predict them. Prediction methods can be divided into landslide susceptibility analysis, landslide hazard analysis and landslide risk analysis according to the type of the conditioning factors, the predicted level of the landslide dangers, and whether the expected consequence cased by landslides were considered. Landslide susceptibility analyses are mainly based on the available landslide data and consequently, they predict the likelihood of landslide occurrence by considering factors that can induce landslides and analyzing the spatial distribution of these factors. Various qualitative and quantitative analysis techniques have been applied to landslide susceptibility analysis. Recently, quantitative susceptibility analyses have predominantly employed the physically based model due to high predictive capacity. This is because the physically based approaches use physical slope model to analyze slope stability regardless of prior landslide occurrence. This approach can also reproduce the physical processes governing landslide occurrence. This review examines physically based landslide susceptibility analysis approaches.

Behavior of Asphalt Pavement Subjected to a Moving Vehicle I: The Effect of Vehicle Speed, Axle-weight, and Tire Inflation Pressure (이동하중에 의한 시험도로 아스팔트 포장의 거동 분석)

  • Seo, Young Gook;Lee, Kwang-Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.5D
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    • pp.831-838
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    • 2006
  • An experimental/analytic study has been conducted to understand the adverse effects of low vehicle speed, high axle load and high tire pressure on the performance of asphalt pavements. Of 33 asphalt sections at KHC test road, two sections having different base layer thickness (180 mm versus 280 mm) are adopted for rollover tests. During the test, a standard three-axle dump truck maintains a steady state condition as moving along the wheel path of a passing lane, and lateral offsets and real travel speed are measured with a laser-based wandering system. Test results suggest that vehicle speed affects both longitudinal and transverse strains at the bottom of asphalt layer (290 mm and 390 mm below the surface), and even slightly influences the measured vertical stresses at the top of subbase and subgrade due to the dynamic effect of rolling vehicle. Since the anisotropic nature of asphalt-aggregate mixtures, the difference between longitudinal and transverse strains appears prominent throughout the measurements. As the thickness of asphalt pavement increases, the measured lateral strains become larger than its corresponding longitudinal strains. Over the limited testing conditions, it is concluded that higher axle weight and higher tire pressures induce more strains and vertical stresses, leading to a premature deterioration of pavements. Finally, a layered elastic analysis overestimates the maximum strains measured under the 1st axle load, while underestimating the maximum vertical stress in both pavement sections.

A Study on Moisture Transport of Artificial Lightweight Concrete (인공경량골재 콘크리트의 수분이동 특성에 관한 연구)

  • Lee, Chang Soo;Choi, Sang Hyun;Park, Jong Hyok;Kim, Young Ook
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.4A
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    • pp.373-384
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    • 2009
  • For the first step on the quantitative evaluation of shrinkage reduction and differential shrinkage analysis of lightweight aggregate concrete, this study sets the moisture transport model of concrete by pre-absorbed water of porous lightweight aggregates and measured effective moisture diffusion coefficient, moisture capacity, degree of humidity supply and degree of humidity consumption by water binder ratio and aggregate type. The effective moisture diffusion coefficient in steady state caused by humidity difference between inside and outside of concrete had low value as low water-binder ratio. And in case of same water-binder ratio, effective moisture diffusion of mixtures used normal aggregates were lower than those used lightweight aggregates. To determine moisture store capability of concrete - moisture capacity, moisture contents were measured in 9 humidity conditions. As a result moisture contents of mixtures used lightweight aggregates was higher than mixtures used normal aggregates in all humidity conditions. This study measured lightweight aggregates' degree of humidity supply that applicable to normal atmospheric environment (above RH 50%) and made it quantitatively. Also amount of moisture release was set as a exponential function that represents a clear trend proportion to time and inverse proportion to humidity of the surroundings. As the result of measurement about degree of moisture consumption inside concrete following the internal consumption caused by cement hydration self-drying, it was showed that rapid decrease of humidity, around 10%, at early ages (7~10 days) when water-binder ratio is 0.3 and slow decrease around 5% and 1% when water-binder ratio is 0.4 and 0.5.

A Comparative Analysis of Efficiency Between Korean and Chinese Banks (한국과 중국 은행의 효율성 비교에 관한 연구)

  • Cho, Dae-Woo;Lee, Dong-Kuk
    • International Area Studies Review
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    • v.15 no.1
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    • pp.341-365
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    • 2011
  • This study used a non-parametric linear program, Data Envelopment Analysis to compare the efficiency of South Korean and Chinese banks from 2000 to 2008, which is said to be the reformation period of their financial structure. The sample banks were 10 commercial banks and 6 regional banks in Korea, and 4 state-owned commercial banks and 11 stock commercial banks in China. The main objective of our research is to compare their efficiency, as well as the changes in efficiency periodically according to the types of the banks. According to the periodical analysis, both of the countries showed steady increase in efficiency. This shows that finance restructure and merging were positive factors for bank's efficiency during the revolution of finance structure. The study showed that between Korea and China, the bank of Korea has higher efficiency than that of China. Although the reconstruction period happened around the same time, due to the earlier acceleration period to opening Korea's financial market, made the difference in efficiency.

Design approach of passive vibration control using damping tape for quadrotor drone in hover (제자리 비행 조건에서 쿼드로터의 감쇠 테이프를 이용한 수동적 진동 제어 설계 방법 연구)

  • Sejun Kim;Hyungmo Kim;Seongwoo Cheon;Sungjun Kim;Haeseong Cho;Lae-Hyong Kang
    • Journal of Aerospace System Engineering
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    • v.18 no.1
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    • pp.37-45
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    • 2024
  • This paper presents a design approach for passive vibration control to reduce vertical vibrations transmitted to the control unit during hovering flight of a quadrotor drone. Ground vibration test simulation based on finite element model was performed for forced vibration analysis of the quadrotor drone. First, modal analysis was performed to evaluate dynamic characteristics. Forced vibration response analysis was then performed to obtain the steady-state response within the operating frequency range under the hovering flight condition. Furthermore, to obtain the vibration reduction effect, a viscous damping tape was applied at positions that could induce vibrations transmitted to the control unit under the same conditions. Such a passive vibration control approach was investigated. Relevant vibration reduction effect was assessed with respect to the application of damping materials and the attachment position.