• Journal of Microbiology and Biotechnology
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• 제30권8호
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• pp.1252-1260
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• 2020

(R)-2-(4-hydroxyphenoxy)propionic acid (HPOPA) is a key intermediate for the preparation of aryloxyphenoxypropionic acid herbicides (R-isomer). In order to improve the HPOPA production from the substrate (R)-2-phenoxypropionic acid (POPA) with Beauveria bassiana CCN-A7, static cultivation and H₂O₂ addition were attempted and found to be conducive to the task at hand. This is the first report on HPOPA production under static cultivation and reactive oxygen species (ROS) induction. On this premise, the cultivation conditions and fermentation medium compositions were optimized. As a result, the optimal carbon source, organic nitrogen source, and inorganic nitrogen source were determined to be glucose, peptone, and ammonium sulfate, respectively. The optimal inoculum size and fermentation temperature were 13.3% and 28℃, respectively. The significant factors including glucose, peptone, and H₂O₂, identified based on Plackett-Burman design, were further optimized through Central Composite Design (CCD). The optimal concentrations were as follows: glucose 38.81 g/l, peptone 7.28 g/l, and H₂O₂ 1.08 g/l/100 ml. Under the optimized conditions, HPOPA titer was improved from 9.60 g/l to 19.53 g/l, representing an increase of 2.03-fold. The results obtained in this work will provide novel strategies for improving the biosynthesis of hydroxy aromatics.

• 한국방재학회 논문집
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• 제10권6호
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• pp.17-25
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• 2010

본 연구는 U-채널 세그멘탈 콘크리트 교량의 차량 충돌 안전성에 대한 연구를 수행하였다. U-채널 세그멘탈 콘크리트 교량은 추가 고정하중을 감소시키고, 측보가 방호벽 역할을 동시에 수행하는 교량이라는 장점을 가지고 있다. 그러나 측보의 파괴는 전체 교량의 붕괴로 이어질 수 있는 위험 요소를 가지고 있다. 따라서, U-채널 세그멘탈 콘크리트 교량 측보의 차량 충돌에 따른 거동분석 및 특성파악이 필요하다고 판단된다. 본 논문에서는 AASHTO LRFD 설계기준 (2007)의 정적 및 동적 차량 충돌해석 기준을 적용하여 U-채널 세그멘탈 콘크리트 교량의 충돌해석을 수행하였다. 정적차량충돌해석의 경우에는 AASHTO LRFD 설계기준 (2007)에서 제시하고 있는 등가정적하중 재하하여 해석을 수행하고, 동적차량충돌의 경우에는 AASHTO LRFD 설계기준 (2007)의 방호벽 충돌실험기준에 근거한 실제 차량을 모델링하여 충돌해석을 통한 안전성 검토를 수행하였다. 검토결과, AASHTO LRFD 설계기준 (2007)을 만족하는 정적 및 동적 충돌하중에 대해 U-채널 교량시스템은 안전성을 확보하고 있는 것으로 판단된다.

• The Journal of Advanced Prosthodontics
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• 제8권5호
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• pp.388-395
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• 2016

PURPOSE. The purpose of this study was to evaluate the resistance to deformation under static overloading by measuring yield and fracture strength, and to analyze the failure characteristics of implant assemblies made of different titanium grades and connections. MATERIALS AND METHODS. Six groups of implant assemblies were fabricated according to ISO 14801 (n=10). These consisted of the combinations of 3 platform connections (external, internal, and morse tapered) and 2 materials (titanium grade 2 and titanium grade 4). Yield strength and fracture strength were evaluated with a computer-controlled Universal Testing Machine, and failed implant assemblies were classified and analyzed by optical microscopy. The data were analyzed using the One-way analysis of variance (ANOVA) and Student's t-test with the level of significance at P=.05. RESULTS. The group $IT4_S$ had the significantly highest values and group IT2 the lowest, for both yield strength and fracture strength. Groups $IT4_N$ and ET4 had similar yield and fracture strengths despite having different connection designs. Group MT2 and group IT2 had significant differences in yield and fracture strength although they were made by the same material as titanium grade 2. The implant system of the similar fixture-abutment interfaces and the same materials showed the similar characteristics of deformation. CONCLUSION. A longer internal connection and titanium grade 4 of the implant system is advantageous for static overloading condition. However, it is not only the connection design that affects the stability. The strength of the titanium grade as material is also important since it affects the implant stability. When using the implant system made of titanium grade 2, a larger diameter fixture should be selected in order to provide enough strength to withstand overloading.

• Physical Therapy Rehabilitation Science
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• 제9권2호
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• pp.105-112
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• 2020

Objective: To investigate the effects of training using a trunk control robot (TCR) system combined with conventional therapy (CT) on balance and gait abilities in persons with chronic stroke. Design: Two-group pretest-posttest design. Methods: Thirty-five subjects with chronic stroke were randomly assigned to either the TCR group (n=17) or the trunk extension-training (TET) group (n=18). Both groups performed CT for 30 minutes, after which the TCR group performed TCR training and the TET group performed trunk extension training for 20 minutes. Both groups performed the therapeutic interventions 3 days per week for 6 weeks. Balance ability was evaluated using the Berg Balance Scale (BBS), and the Timed Up-and-Go (TUG) test. Gait ability was measured using the 10 m Walk Test (10MWT) and the NeuroCom Smart Balance Master. Results: TCR group showed significant improvements in static balance (weight bearing) and dynamic balance (weight shifting speed, weight shifting direction, BBS, and TUG), 10MWT, gait speed, and step width (p<0.05); step length was not significant. The TET group showed a significant partial improvement of dynamic balance (weight shifting speed, weight shifting direction, BBS, and 10MWT (p<0.05), but the improvements in static balance, TUG, gait speed, and step width and step length was not significant. Additionally, significant differences in static balance, dynamic balance (weight shifting speed, weight shifting direction, BBS, and TUG), 10MWT, gait speed, and step width were detected between groups (p<0.05). Conclusions: TCR training combined with CT is effective in improving static and dynamic balance, as well as gait abilities in persons with chronic stroke.

• 한국강구조학회 논문집
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• 제18권2호
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• pp.173-180
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• 2006

구조물의 지진응답은 기초지반조건의 영향을 받는다. 이 연구에서는 고정지반과 연약지반을 고려한 3, 5, 7층 철골 건축구조물의 밑면전단력을 산정하기 위해 선형 시간이력지진해석과 비선형 Pushover 정적지진해석을 수행하였다. 등가정적강성식으로 구한 기초지반강성은 SAP2000의 Link 요소 중 Damper 요소를 사용하여 입력하였다. 범용구조해석 프로그램 SAP2000에 의한 시간이력으로 구한 철골건축구조물의 밑면전단력을 국내내진설계기준, UBC-97 설계응답스펙트럼, Pushover 정적 비선형해석으로 구한 밑면전단력과 비교하였다. 중력하중과 풍하중으로 설계된 철골 건축구조물은 0.11g의 중진에 대해 탄성응답을 보였고, 탄성 연약지반에서 구조물-지반의 상호작용과 지반 증폭에 의해 구조물의 변위와 밑면전단력이 증가되었다. 따라서, 중약진 지역에서의 건축구조물은 연약지반의 특성을 고려하여 탄성지진해석을 수행하는 것이 더 합리적이다.

• Tribology and Lubricants
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• 제36권6호
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• pp.332-341
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• 2020

High-speed turbomachinery implements gas foil bearings (GFBs) due to their distinctive advantages, such as high efficiency, lesser part count, and lower weight. This paper provides the test results of the static structural stiffnesses and loss factors of bump-type foil thrust bearings with increasing preload and bearing deflection. The focus of the current work is to experimentally quantify variability in structural stiffnesses and loss factors among the four test thrust bearings with identical design values and material of the bump and top foil geometries using the same (open-source) fabrication method. A simple test setup, using a rigidly mounted non-rotating shaft and thrust disk, measures the bearing bump deflections with increasing static loads on the test bearing. The inner and outer diameters of the test bearings are 41 mm and 81 mm, respectively. The loss factor, best-representing energy dissipation in the test bearings, is estimated from the area inside the local hysteresis loop of the load versus the bearing deflection curve. The measurements show that structural stiffnesses and loss factors of the test bearings significantly rely on applied preloads and bearing deflections. Local structural stiffnesses of the test bearings increase with applied preloads but decrease with bearing deflections. Changes of loss factors are less sensitive to applied preloads and bearing deflections compared to those of structural stiffnesses. Up to 35% variability in static load structural stiffnesses is found between bearings, while up to 30% variability in loss factors is found between bearings.

• Steel and Composite Structures
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• 제48권2호
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• pp.113-130
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• 2023

The present manuscript aims to investigate the deviation between the middle surface (MS) and neutral surface (NS) formulations on the static response of bi-directionally functionally graded (BDFG) porous plate. The higher order shear deformation plate theory with a four variable is exploited to define the displacement field of BDFG plate. The displacement field variables based on both NS and on MS are presented in detail. These relations tend to get and derive a new set of boundary conditions (BCs). The porosity distribution is portrayed by cosine function including three different configurations, center, bottom, and top distributions. The elastic foundation including shear and normal stiffnesses by Winkler-Pasternak model is included. The equilibrium equations based on MS and NS are derived by using Hamilton's principles and expressed by variable coefficient partial differential equations. The numerical differential quadrature method (DQM) is adopted to solve the derived partial differential equations with variable coefficient. Rigidities coefficients and stress resultants for both MS and NS formulations are derived. The mathematical formulation is proved with previous published work. Additional numerical and parametric results are developed to present the influences of modified boundary conditions, NS and MS formulations, gradation parameters, elastic foundations coefficients, porosity type and porosity coefficient on the static response of BDFG porous plate. The following model can be used in design and analysis of BDFG structure used in aerospace, vehicle, dental, bio-structure, civil and nuclear structures.

• 항공우주기술
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• 제4권1호
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• pp.129-142
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• 2005

KSLV-I의 위성 어댑터의 구조 형식으로 결정된 세미 모노코크 형식의 잘려진 원뿔형 구조체를 제작하고, 정적 구조 시험을 수행하였다. 설계 하중에 따라 순수 압축, 순수 굽힘, 순수 전단, 복합 하중을 가하여 변형률 및 변위를 측정하고, 구조의 건전성을 확인하였다. 최종적으로 파괴 시험을 수행하여, 국부 좌굴 모드 및 파괴 형상을 관찰하였으며, 파괴하중 및 모드를 유한 요소법으로 해석하여 비교한 결과 정확한 파괴 하중의 예측이 가능하였다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2009년도 추계학술대회 논문집
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• pp.473-477
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• 2009

In general, the softer the stiffness of a linear vibration isolator the better the performance of isolation can be achieved. However, the stiffness of the isolator cannot be made too soft because it needs a sufficient stiffness to hold the load. This is the most critical limitation of a linear vibration isolator. Recently, a HSLDS (High-Static-Low-Dynamic-Stiffness) magnetic vibration isolator was proposed to overcome this fundamental limitation. The suggested isolator utilizes two pairs of attracting magnets that that introduces negative stiffness. Previously, this new type of vibration isolator was merely introduced and showed a possibility of practical use. In this paper, detailed dynamics of the HSLDS magnetic isolator are studied using computer simulations. Then, the isolation performance is examined for various design parameters to aid the practical use.

• 한국정밀공학회지
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• 제25권8호
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• pp.96-103
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• 2008

In this study, we performed the biomechanical analysis of cervical plate systems by using a computer simulation based on finite element method to derive reliable model by analysis of design variables and fatigue behavior. To simulate the cervical spine movement in-vivo state by surgery, we modeled the cervical plate system which consisted of screws, rings, rivets, and plate and Ultra High Molecular Weight Polyethylene (UHMWPE) Block. The experiment of cervical plate system followed the ASTM F1717 standards that covered the materials and methods for the static and fatigue testing. The result of computer simulation is compared with experimented test. We expected this study is to derive reliable results by analysis of design variables and fatigue behavior for developing a new model.